keyword
MENU ▼
Read by QxMD icon Read
search

Pandya

keyword
https://www.readbyqxmd.com/read/28424389/-brodmann-areas-8-and-9-including-the-frontal-eye-field
#1
Masataka Watanabe
Based on cytoarchitectonic analyses, Brodmann assigned numbers 8 and 9 to certain areas of the dorsal and medial prefrontal cortex (PFC) in humans and monkeys. Petrides and Pandya re-analyzed the cytoarchitectures of the human and monkey PFCs, and proposed slightly different brain maps for both species. They assigned numbers 8, 9 and 9/46 to the areas that were originally named areas 8 and 9. Areas 8 and 9 have both lateral and medial regions respectively. The lateral area 8 is important for conditional discrimination learning...
April 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28418614/efficacy-and-safety-of-low-dose-heparin-in-hemodialysis
#2
Mariana Murea, Gregory B Russell, Pirouz Daeihagh, Anita M Saran, Karan Pandya, Mark Cabrera, John M Burkart, Barry I Freedman
INTRODUCTION: The dose of unfractionated heparin (UFH) administered during hemodialysis (HD) varies widely. This prospective study evaluated the safety and efficacy of UFH dose de-escalation. METHODS: Sixty-six prevalent patients on HD receiving UFH per standard-dose protocol (load dose [LD] 50-75 units/kg, maintenance dose [MD] 500-1000 units/hour) had heparin prescription converted to low-dose protocol (start LD 15 units/kg and MD 500 units/hour; dose adjusted in small increments based on assessments of extracorporeal blood circuit)...
April 18, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28415411/quality-by-design-approach-for-an-in-situ-gelling-microemulsion-of-lorazepam-via-intranasal-route
#3
Vidhi Shah, Mukesh Sharma, Radhika Pandya, Rajesh K Parikh, Bhavesh Bharatiya, Atindra Shukla, Hsieh-Chih Tsai
The present study illustrates the application of the concept of Quality by Design for development, optimization and evaluation of Lorazepam loaded microemulsion containing ion responsive In situ gelator gellan gum and carbopol 934. A novel approach involving interactions between surfactant and polymer was employed to achieve controlled drug release and reduced mucociliary clearance. Microemulsion formulated using preliminary solubility study and pseudo ternary phase diagrams showed significantly improved solubilization capacity of Lorazepam with 54...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28413271/assist-patient-satisfaction-survey-in-postoperative-pain-management-from-indian-subcontinent
#4
Balavenkata Subramanian, Naman Shastri, Lutful Aziz, Ramachandran Gopinath, Anil Karlekar, Yatin Mehta, Anand Sharma, Jitendra Suhas Bapat, Pradeep Jain, Aveek Jayant, Tanvir Samra, Ajantha Perera, Anil Agarwal, Vijay Shetty, Sushma Bhatnagar, Sunil T Pandya, Paramanand Jain
INTRODUCTION: To compare pain scores at rest and ambulation and to assess patient satisfaction between the different modalities of pain management at different time points after surgery. SETTINGS AND DESIGN: The ASSIST (Patient Satisfaction Survey: Pain Management) was an investigator-initiated, prospective, multicenter survey conducted among 1046 postoperative patients from India. MATERIAL AND METHODS: Pain scores, patient's and caregiver's satisfaction toward postoperative pain treatment, and overall pain management at the hospital were captured at three different time points through a specially designed questionnaire...
January 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28412225/enhancing-tissue-permeability-with-mri-guided-preclinical-focused-ultrasound-system-in-rabbit-muscle-from-normal-tissue-to-vx2-tumor
#5
Yao Sun, Xiaobing Xiong, Darpan Pandya, Youngkyoo Jung, Akiva Mintz, Satoru Hayasaka, Thaddeus J Wadas, King C P Li
High Intensity Focused Ultrasound (HIFU) is an emerging noninvasive, nonionizing physical energy based modality to ablate solid tumors with high power, or increase local permeability in tissues/tumors in pulsed mode with relatively low power. Compared with traditional ablative HIFU, nondestructive pulsed HIFU (pHIFU) is present in the majority of novel applications recently developed for enhancing the delivery of drugs and genes. Previous studies have demonstrated the capability of pHIFU to change tissue local permeability for enhanced drug delivery in both mouse tumors and mouse muscle...
April 12, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28411101/-surgical-management-of-primary-spindle-cell-sarcoma-of-prostate
#6
Keval N Patel, Rohit K Jha, Shashank J Pandya
Primary spindle cell sarcoma of prostate is an extremely rare malignancy and very few cases of it have been reported [1, 2]. We searched literature through Med-Line database using Pub-Med and Scopus for the articles published between January 1988 and September 2016. Our search was limited to the following keywords: "spindle cell sarcoma", "prostate" and "surgical management". Most of the papers focused on histopathology of the tumour; very few were found discussing the surgical management. We here present a case of localized primary spindle cell sarcoma of prostate operated at our institute with the difficulties we faced and their management...
April 11, 2017: Urology
https://www.readbyqxmd.com/read/28403653/congenital-pseudoarthrosis-of-the-distal-radius-treated-with-physeal-sparing-double-barrel-vascularized-free-fibula-transfer-a-case-report
#7
David Y Ding, Joey LaMartina, Chau Tai, Nirav K Pandya
BACKGROUND: Neurofibromatosis type 1 is a hereditary disease that can lead to pseudoarthrosis of various long bones. Rarely, pseudoarthrosis affects the forearm, and to the best of our knowledge, this is the first reported case of pseudarthrosis of the distal radius treated by this unique method. METHODS: We present a case of a 7-year-old male who underwent multiple operations to treat pseudoarthrosis of the distal radius. RESULTS: After failed conservative and operative fixation augmented with autologous iliac crest bone grafting, the patient underwent a successful double-barrel vascularized free fibula graft while preserving the physis of the distal radius...
April 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28397485/large-area-cross-aligned-silver-nanowire-electrodes-for-flexible-transparent-and-force-sensitive-mechanochromic-touch-screens
#8
Seungse Cho, Saewon Kang, Ashish Pandya, Ravi Shanker, Ziyauddin Khan, Youngsu Lee, Jonghwa Park, Stephen L Craig, Hyunhyub Ko
Silver nanowire (AgNW) networks are considered to be promising structures for use as flexible transparent electrodes for various optoelectronic devices. One important application of AgNW transparent electrodes is the flexible touch screens. However, the performances of flexible touch screens are still limited by the large surface roughness and low electrical to optical conductivity ratio of random network AgNW electrodes. In addition, although the perception of writing force on the touch screen enables a variety of different functions, the current technology still relies on the complicated capacitive force touch sensors...
April 12, 2017: ACS Nano
https://www.readbyqxmd.com/read/28382833/dr-john-mclennan-md-aberdeen-frcp-lond-1801-1874-and-the-medical-school-of-bombay-that-failed
#9
Sunil K Pandya
In 1826, Dr John McLennan was asked by Governor Mounstuart Elphinstone of Bombay to set up the first school to teach modern medicine to Indian citizens. He was expected to create textbooks on a variety of subjects in local languages and teach medicine to poorly educated students in their native tongues. Despite his valiant efforts, the school was deemed a failure and was abolished by the Government in 1832. Sir Robert Grant, appointed Governor of Bombay in 1835, analysed records pertaining to this medical school and concluded that the school failed since Dr McLennan was not provided the assistance he needed and as his suggestions for access to a hospital to teach medicine were not heeded...
January 1, 2017: Journal of Medical Biography
https://www.readbyqxmd.com/read/28380672/randomized-clinical-trial-of-deep-brain-stimulation-for-post-stroke-pain
#10
Scott F Lempka, Donald A Malone, Bo Hu, Kenneth B Baker, Alexandria Wyant, John Ozinga, Ela B Plow, Mayur Pandya, Cynthia S Kubu, Paul J Ford, Andre G Machado
OBJECTIVE: The experience with deep brain stimulation (DBS) for pain is largely based on uncontrolled studies targeting the somatosensory pathways, with mixed results. We hypothesized that targeting limbic neural pathways would modulate the affective sphere of pain and alleviate suffering. METHODS: We conducted a prospective, double-blinded, randomized, placebo-controlled, crossover study of DBS targeting the ventral striatum/anterior limb of the internal capsule (VS/ALIC) in 10 patients with post-stroke pain syndrome...
April 5, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28379638/meeting-report-vitiligo-global-issues-consensus-conference-vgicc-workshop-outcome-measurement-instruments-and-vitiligo-international-symposium-rome-nov-30-dec-3-rd
#11
Nanja van Geel, Katia Boniface, Julien Seneschal, Clément Jacquemin, Reinhart Speeckaert, Albert Wolkerstorfer, Marcel Bekkenk, Janny E Lommerts, Iltefat Hamzavi, Amit Pandya, Viktoria Eleftheriadou, Khaled Ezzedine, Diana Giannarelli, Maria Gnarra, Isabella Sperduti, Cecilia Prinsen, John Harris, Alain Taieb, Mauro Picardo
The international vitiligo community had last December its first "vitiligo only" research meeting in the Eternal City. Vitiligo is a well-recognized but poorly addressed public health concern worldwide. The Vitiligo International Symposium (VIS) is a strong signal for the medical world of the coming of age of vitiligo as a major research field. Because of the gathering of the majority of world experts, the meeting was preceded by a clinical research methodology workshop held at the San Gallicano Institute. This report gives a combined account of the two parts...
April 5, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/28371753/a-microfluidic-platform-for-drug-screening-in-a-3d-cancer-microenvironment
#12
Hardik J Pandya, Karan Dhingra, Devbalaji Prabhakar, Vineethkrishna Chandrasekar, Siva Kumar Natarajan, Anish S Vasan, Ashish Kulkarni, Hadi Shafiee
Development of resistance to chemotherapy treatments is a major challenge in the battle against cancer. Although a vast repertoire of chemotherapeutics is currently available for treating cancer, a technique for rapidly identifying the right drug based on the chemo-resistivity of the cancer cells is not available and it currently takes weeks to months to evaluate the response of cancer patients to a drug. A sensitive, low-cost diagnostic assay capable of rapidly evaluating the effect of a series of drugs on cancer cells can significantly change the paradigm in cancer treatment management...
March 27, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28362388/analyzing-dendritic-morphology-in-columns-and-layers
#13
Chun-Yuan Ting, Philip G McQueen, Nishith Pandya, Evan S McCreedy, Matthew McAuliffe, Chi-Hon Lee
In many regions of the central nervous systems, such as the fly optic lobes and the vertebrate cortex, synaptic circuits are organized in layers and columns to facilitate brain wiring during development and information processing in developed animals. Postsynaptic neurons elaborate dendrites in type-specific patterns in specific layers to synapse with appropriate presynaptic terminals. The fly medulla neuropil is composed of 10 layers and about 750 columns; each column is innervated by dendrites of over 38 types of medulla neurons, which match with the axonal terminals of some 7 types of afferents in a type-specific fashion...
March 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28360947/a-novel-method-for-isolation-of-histones-from-serum-and-its-implications-in-therapeutics-and-prognosis-of-solid-tumours
#14
Divya Reddy, Bharat Khade, Riddhi Pandya, Sanjay Gupta
BACKGROUND: Dysregulation in post-translational modifications of histones and their modifiers are now well-recognized as a hallmark of cancer and can be used as biomarkers and potential therapeutic targets for disease progression and prognosis. In most solid tumours, a biopsy is challenging, costly, painful or potentially risky for the patient. Therefore, non-invasive methods like 'liquid biopsy' for analysis of histone modifications and their modifiers if possible will be helpful in the better clinical management of cancer patients...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28352668/genomic-profiling-reveals-mutational-landscape-in-parathyroid-carcinomas
#15
Chetanya Pandya, Andrew V Uzilov, Justin Bellizzi, Chun Yee Lau, Aye S Moe, Maya Strahl, Wissam Hamou, Leah C Newman, Marc Y Fink, Yevgeniy Antipin, Willie Yu, Mark Stevenson, Branca M Cavaco, Bin T Teh, Rajesh V Thakker, Hans Morreau, Eric E Schadt, Robert Sebra, Shuyu D Li, Andrew Arnold, Rong Chen
Parathyroid carcinoma (PC) is an extremely rare malignancy lacking effective therapeutic intervention. We generated and analyzed whole-exome sequencing data from 17 patients to identify somatic and germline genetic alterations. A panel of selected genes was sequenced in a 7-tumor expansion cohort. We show that 47% (8 of 17) of the tumors harbor somatic mutations in the CDC73 tumor suppressor, with germline inactivating variants in 4 of the 8 patients. The PI3K/AKT/mTOR pathway was altered in 21% of the 24 cases, revealing a major oncogenic pathway in PC...
March 23, 2017: JCI Insight
https://www.readbyqxmd.com/read/28351882/rahi-sathi-indo-u-s-collaboration-the-evolution-of-a-trainee-led-twinning-model-in-global-health-into-a-multidisciplinary-collaborative-program
#16
Apurv Soni, Nisha Fahey, Abraham Jaffe, Shyamsundar Raithatha, Nitin Raithatha, Anusha Prabhakaran, Tiffany A Moore Simas, Nancy Byatt, Jagdish Vankar, Michael Chin, Ajay G Phatak, Shirish Srivastava, David D McManus, Eileen O'Keefe, Harshil Patel, Niket Patel, Dharti Patel, Michaela Tracey, Jasmine A Khubchandani, Haley Newman, Allison Earon, Hannah Rosenfield, Anna Handorf, Brittany Novak, John Bostrom, Anindita Deb, Soaham Desai, Dipen Patel, Archana Nimbalkar, Kandarp Talati, Milagros Rosal, Patricia McQuilkin, Himanshu Pandya, Heena P Santry, Sunil Thanvi, Utpala Kharod, Melissa Fischer, Jeroan Allison, Somashekhar M Nimbalkar
BACKGROUND: In recent years there has been a surge in the number of global health programs operated by academic institutions. However, most of the existing programs describe partnerships that are primarily faculty-driven and supported by extramural funding. PROGRAM DESCRIPTION: Research and Advocacy for Health in India (RAHI, or "pathfinder" in Hindi) and Support and Action Towards Health-Equity in India (SATHI, or "partnership" in Hindi) are 2 interconnected, collaborative efforts between the University of Massachusetts Medical School (UMMS) and Charutar Arogya Mandal (CAM), a medical college and a tertiary care center in rural western India...
March 24, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28343834/evaluating-the-impact-of-obesity-on-safety-and-efficacy-of-weight-based-norepinephrine-dosing-in-septic-shock-a-single-center-retrospective-study
#17
Paul J Wong, Komal A Pandya, Alexander H Flannery
OBJECTIVE: Norepinephrine is the first-line vasopressor recommended for patients in septic shock. Weight-based dosing may increase drug exposure and the risk of adverse effects in obese patients. The objective was to evaluate the safety and efficacy of weight-based norepinephrine dosing using actual body weight in the morbidly obese compared with normal weight patients. METHODS: This was a single centre, retrospective study of adult patients admitted with septic shock requiring norepinephrine for at least 12hours...
March 23, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28343151/gastric-outlet-obstruction-an-unusual-case-of-primary-duodenal-tuberculosis
#18
Sanket Kalpande, Jayashri Sanjay Pandya, Ajeet Tiwari, Devbrata Adhikari
BACKGROUND: Tuberculosis is a major health problem worldwide. Gastrointestinal tuberculosis presenting as isolated involvement of the duodenum is a rare case. CASE PRESENTATION: A 13 year male, presented with features of gastric outlet obstruction. CT enterography scan showed circumferential mural thickening in first and second part of duodenal junction causing luminal narrowing. Upper GI endoscopy confirmed the narrowing of D1-D2 junction. Duodenal biopsy showed duodenitis with negative result for AFB stain, Helicobacter Pylori...
March 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28341789/met-tyrosine-kinase-inhibition-enhances-the-antitumor-efficacy-of-an-hgf-antibody
#19
Pamela J Farrell, Jennifer Matuszkiewicz, Deepika Balakrishna, Shweta Pandya, Mark S Hixon, Ruhi Kamran, Shaosong Chu, J David Lawson, Kengo Okada, Akira Hori, Akio Mizutani, Hidehisa Iwata, Ron de Jong, Barbara Hibner, Patrick Vincent
Receptor tyrosine kinase therapies have proven to be efficacious in specific cancer patient populations, however, a significant limitation of tyrosine kinase inhibitor (TKI) treatment is the emergence of resistance mechanisms leading to a transient, partial or complete lack of response. Combination therapies using agents with synergistic activity have potential to improve response and reduce acquired resistance. Chemoreagent or TKI treatment can lead to increased expression of HGF and/or MET and this effect correlates with increased metastasis and poor prognosis...
March 24, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28341718/relationships-among-cortical-glutathione-levels-brain-amyloidosis-and-memory-in-healthy-older-adults-investigated-in-vivo-with-1-h-mrs-and-pittsburgh-compound-b-pet
#20
G C Chiang, X Mao, G Kang, E Chang, S Pandya, S Vallabhajosula, R Isaacson, L D Ravdin, D C Shungu
BACKGROUND AND PURPOSE: Oxidative stress has been implicated as an important pathologic mechanism in the development of Alzheimer disease. The purpose of this study was to assess whether glutathione levels, detected noninvasively with proton MR spectroscopy, are associated with brain amyloidosis and memory in a community-dwelling cohort of healthy older adults. MATERIALS AND METHODS: Fifteen cognitively healthy subjects were prospectively enrolled in this study...
March 24, 2017: AJNR. American Journal of Neuroradiology
keyword
keyword
73525
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"