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https://www.readbyqxmd.com/read/29141266/-impact-of-abdominal-ultrasound-on-the-identification-of-the-site-of-infection-in-the-emergency-department-analysis-whether-it-makes-sense-to-perform-abdominal-ultrasound-examination-for-the-identfication-of-the-site-of-infection-if-medical-history-and-clinical
#1
Barbara Werkmeister, Julia Langgartner, Doris Schacherer, Arno Mohr
Introduction A very high number of patients presenting in emergency departments suffer from an unknown infection or rather fever. If diagnostic imaging is necessary ultrasound can be performed. Whether ultrasound is superior to medical history and clinical examination considering the significantly enhanced technology in recent years and hence has to be performed in patients without abdominal symptoms with non-obvious focus cannot be answered by review of the literature. The objective of this study was to evaluate the relevance of abdominal ultrasound in the determination of the site of infection and to analyse whether an abdominal ultrasound for the identification of the source of infection is dispensable in patients in whom history and clinical examination do not indicate an abdominal focus...
November 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29132465/-application-of-flexible-bronchoscopy-in-children-with-respiratory-diseases
#2
Li-Ping Wang, Shou-Ping Chen, Yu-Ying Huang, Fang-Fang Qin, Wen Ou, Hong-Dong Liu, Xiao-Fang Deng, Lei Lou, Jing Tao, Yu-Xia Cui
OBJECTIVE: To investigate the significance of flexible bronchoscopy in children with respiratory diseases. METHODS: A retrospective analysis was performed for the clinical data of 80 children who were hospitalized due to respiratory diseases (including severe pneumonia, Mycoplasma pneumoniae pneumonia with atelectasis/lung consolidation/local emphysema, protracted pneumonia, coughing and wheezing of unknown cause, chronic cough of unknown cause, and laryngeal stridor) and who underwent flexible bronchoscopy/alveolar lavage...
November 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29123888/cardiac-arrest-caused-by-rapidly-increasing-ascites-in-a-patient-with-tafro-syndrome-a-case-report
#3
Masatoshi Okumura, Atsushi Ujiro, Yasunori Otsuka, Hiroshi Yamamoto, Sho Wada, Hirofumi Iwata, Toshiaki Kan, Seiji Miyauchi, Atsushi Hashimoto, Yuko Sato, Yoshihito Fujita, Yoshihiro Fujiwara, Hideki Shimaoka
Case: Thrombocytopenia, anasarca, fever, renal insufficiency, and organomegaly (TAFRO) syndrome is a newly defined systemic inflammatory disorder with gradual progression of symptoms. A 59-year-old man with fever and ascites of unknown cause developed sudden-onset shock and respiratory failure in the general ward. Cardiac arrest immediately followed. Although he was resuscitated, frequent administration of adrenaline was required to maintain his blood pressure. His circulation was most effectively stabilized by drainage of fluid from his distended abdomen...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29121947/interleukin-1%C3%AE-signaling-in-fenestrated-capillaries-is-sufficient-to-trigger-sickness-responses-in-mice
#4
J Gabriel Knoll, Stephanie M Krasnow, Daniel L Marks
BACKGROUND: The physiological and behavioral symptoms of sickness, including fever, anorexia, behavioral depression, and weight loss can be both beneficial and detrimental. These sickness responses are triggered by pro-inflammatory cytokines acting on cells within the brain. Previous research demonstrates that the febrile response to peripheral insults depends upon prostaglandin production by vascular endothelial cells, but the mechanisms and specific cell type(s) responsible for other sickness responses remain unknown...
November 9, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29117102/mechanisms-of-entry-and-endosomal-pathway-of-african-swine-fever-virus
#5
REVIEW
Elena G. Sánchez, Daniel Pérez-Núñez, Yolanda Revilla
African Swine Fever Virus (ASFV) causes a serious swine disease that is endemic in Africa and Sardinia and presently spreading in Russia and neighboring countries, including Poland and recently, the Czech Republic. This uncontrolled dissemination is a world-wide threat, as no specific protection or vaccine is available. ASFV is a very complex icosahedral, enveloped virus about 200 nm in diameter, which infects several members of pigs. The virus enters host cells by receptor-mediated endocytosis that depends on energy, vacuolar pH and temperature...
November 8, 2017: Vaccines
https://www.readbyqxmd.com/read/29110927/fever-of-unknown-origin-in-a-laboratory-worker
#6
Irene López Ramos, Jorge Galván Fernández, Antonio Orduña Domingo
No abstract text is available yet for this article.
October 27, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29101676/long-term-follow-up-of-paediatric-mefv-carriers
#7
Balahan Makay, Nesrin Gülez
Although familial Mediterranean fever (FMF) is inherited autosomal recessively, some heterozygotes may express disease phenotype and require therapy. To date, there is no study in the literature about how to follow-up Mediterranean fever (MEFV) heterozygotes who do not fulfil FMF criteria in the paediatric age group. This study aims to share a single-centre experience of the long-term clinical and laboratory follow-up of paediatric MEFV carriers. We reviewed the charts of 69 children who were heterozygous for MEFV variants...
November 3, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29089379/cardiac-tamponade-in-a-child-with-fever-of-unknown-origin
#8
Susan S Li, Zachary Rossfeld, Sanmit K Basu
No abstract text is available yet for this article.
October 31, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/29089020/transcriptomic-study-of-salmonella-enterica-subspecies-enterica-serovar-typhi-biofilm
#9
Khee Chian Jason Chin, Todd Duane Taylor, Maxime Hebrard, Kogaan Anbalagan, Marjan Ganjali Dashti, Kia Kien Phua
BACKGROUND: Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S. Typhi). In chronic carriers, the bacteria survive the harsh environment of the gallbladder by producing biofilm. The phenotype of S. Typhi biofilm cells is significantly different from the free-swimming planktonic cells, and studies have shown that they are associated with antibiotic resistance, immune system evasion, and bacterial persistence. However, the mechanism of this transition and the events leading to biofilm formation are unknown...
October 31, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29083983/investigation-on-mosquito-borne-viruses-at-lancang-river-and-nu-river-watersheds-in-southwestern-china
#10
Lingli Li, Xiaofang Guo, Qiumin Zhao, Yigang Tong, Hang Fan, Qiang Sun, Shaozhen Xing, Hongning Zhou, Jiusong Zhang
During 2007 and 2010, an extensive entomological survey was performed to assess the distribution of mosquitoes and mosquito-borne arboviruses at Lancang River and Nu River watersheds in southwestern China. A total of 20,450 mosquitoes consisting 20 species was trapped and submitted 261 pools according to species and location. Culex tritaeniorhynchus and Anopheles sinensis were the most abundant species. Eighty-seven isolates representing 11 virus species in 8 genera were obtained from 6 mosquito species. The new isolates were identified as Getah virus (GETV), Japanese encephalitis virus (JEV), Yunnan Culex-related flavivirus (YNCxFV), Yunnan Aedes-related flavivirus (YNAeFV), Banna virus (BAV), Yunnan orbivirus (YUOV), Banna orbivirus (BAOV), Yunnan totivirus (YNToV), Nam Dinh virus (NDiV), Menghai rhabdovirus (MRV), and Anopheles minimus iridovirus (AMIV)...
October 30, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29076677/pattern-of-presentation-among-adults-hospitalized-with-dengue-disease
#11
Abdul Rauf, Nasir Hussain Shah Kazmi, Haidar Zaman, Saima Gillani, Tariq Shah, Faizan Malik, Shoaib Ismaeel
BACKGROUND: Dengue is a mosquito born viral infection that has rapidly spread in the world particularly in Southeast Asia. The aim of this hospital based study was to see the demographic, clinical and laboratory characteristics in adults with dengue infection in Hazara region of Northern Pakistan. METHODS: This is a descriptive study. Clinical, laboratory and demographic information were collected from adult patients with suspected dengue infection (n=100) and then managed in one of medical units of tertiary care hospital in Abbottabad from August to October 2015...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29073781/pancytopenia-and-fever-of-unknown-origin-in-a-12-year-old-boy
#12
Ethan Speir, Courtney Charvat, Sarah Varghese
No abstract text is available yet for this article.
October 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/29054546/identification-and-molecular-characterization-of-spotted-fever-group-rickettsiae-in-ticks-collected-from-farm-ruminants-in-lebanon
#13
Isabel G Fernández de Mera, Valeria Blanda, Alessandra Torina, Mayssaa Fawaz Dabaja, Ali El Romeh, Alejandro Cabezas-Cruz, José de la Fuente
Tick-borne diseases have become a world health concern, emerging with increasing incidence in recent decades. Spotted fever group (SFG) rickettsiae are tick-borne pathogens recognized as important agents of human tick-borne diseases worldwide. In this study, 88 adult ticks from the species Hyalomma anatolicum, Rhipicephalus annulatus, Rh. bursa, Rh. sanguineus sensu lato, and Rh. turanicus, were collected from farm ruminants in Lebanon, and SFG rickettsiae were molecularly identified and characterized in these ticks...
October 12, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29050838/three-children-of-meningoencephalitis-with-kikuchi-necrotizing-lymphadenitis
#14
Joung-Hee Byun, Su Eun Park, Sang Ook Nam, Young A Kim, Young Mi Kim, Gyu Min Yeon, Yun-Jin Lee
BACKGROUND: Kikuchi necrotizing lymphadenitis (KNL) is a rare and benign cause of lymphadenopathy, most often cervical. The etiology of KNL remains unknown. Central nervous system (CNS) involvement, such as in meningoencephalitis, is a very rare clinical manifestation of KNL, especially in children. CASE REPORTS: A 12-year-old boy presented with unilateral cervical lymphadenopathy and fever. Histopathological findings led to the diagnosis of KNL. He revisited due to severe headache and vomiting one week later...
October 16, 2017: Brain & Development
https://www.readbyqxmd.com/read/29046752/an-exceedingly-rare-adrenal-collision-tumor-adrenal-adenoma-metastatic-breast-cancer-myelolipoma
#15
Dongyan Liu, Sahayini A Kumar
Adrenal collision tumors (ACTs), in which distinct tumors coexist without histological intermingling in the same adrenal gland, are rare and their actual prevalence is unknown. ACTs commonly consist of adrenal cortical adenoma, myelolipoma, or metastatic malignant tumor. We report a 58-year-old woman with a past history of breast cancer, who presented with a 1 month history of fevers, chills, and abdominal fullness. The physical examination and the laboratory data including endocrine studies were unremarkable...
October 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29043660/sera-of-peruvians-with-fever-of-unknown-origins-include-viral-nucleic-acids-from-non-vertebrate-hosts
#16
Tung Gia Phan, Juana Del Valle Mendoza, Mohammadreza Sadeghi, Eda Altan, Xutao Deng, Eric Delwart
Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample...
October 17, 2017: Virus Genes
https://www.readbyqxmd.com/read/29040788/familial-mediterranean-fever-mutations-are-hypermorphic-mutations-that-specifically-decrease-the-activation-threshold-of-the-pyrin-inflammasome
#17
Yvan Jamilloux, Lucie Lefeuvre, Flora Magnotti, Amandine Martin, Sarah Benezech, Omran Allatif, Mathilde Penel-Page, Véronique Hentgen, Pascal Sève, Mathieu Gerfaud-Valentin, Agnès Duquesne, Marine Desjonquères, Audrey Laurent, Vanessa Rémy-Piccolo, Rolando Cimaz, Luca Cantarini, Emilie Bourdonnay, Thierry Walzer, Bénédicte F Py, Alexandre Belot, Thomas Henry
Objectives: FMF is the most frequent autoinflammatory disease and is associated in most patients with bi-allelic MEFV mutations. MEFV encodes Pyrin, an inflammasome sensor activated following RhoGTPase inhibition. The functional consequences of MEFV mutations on the ability of Pyrin variants to act as inflammasome sensors are largely unknown. The aim of this study was to assess whether MEFV mutations affect the ability of Pyrin to detect RhoGTPase inhibition and other inflammasome stimuli...
October 12, 2017: Rheumatology
https://www.readbyqxmd.com/read/29036369/referral-of-patients-with-fever-of-unknown-origin-to-an-expertise-center-has-high-diagnostic-and-therapeutic-value
#18
Catharina M Mulders-Manders, Gianni Pietersz, Anna Simon, Chantal P Bleeker-Rovers
Background: up to 50% of patients with fever of unknown origin (FUO) remain undiagnosed despite extensive evaluation. In expertise centers, at least 25-63% of these patients is referred after evaluation in another hospital. The diagnostic and therapeutic yields of referral to an expertise center are currently unknown. Aim: To determine the diagnostic and therapeutic yield of referral of patients with fever of unknown origin (FUO) that remain undiagnosed in non-expertise hospitals...
July 28, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29034876/quantifying-the-contribution-of-plasmodium-falciparum-malaria-to-febrile-illness-amongst-african-children
#19
Ursula Dalrymple, Ewan Cameron, Samir Bhatt, Daniel J Weiss, Sunetra Gupta, Peter W Gething
Suspected malaria cases in Africa increasingly receive a rapid diagnostic test (RDT) before antimalarials are prescribed. While this ensures efficient use of resources to clear parasites, the underlying cause of the individual's fever remains unknown due to potential coinfection with a non-malarial febrile illness. Widespread use of RDTs does not necessarily prevent over-estimation of clinical malaria cases or sub-optimal case management of febrile patients. We present a new approach that allows inference of the spatiotemporal prevalence of both Plasmodium falciparum malaria-attributable and non-malarial fever in sub-Saharan African children from 2006 to 2014...
October 16, 2017: ELife
https://www.readbyqxmd.com/read/29033518/a-rare-experience-of-infective-residual-sheath-in-the-wall-of-the-innominate-vein-after-extraction-of-implantable-defibrillators
#20
Yuan-Hao Liu, Wei-Shiang Lin, Yi-Chang Lin, Chih-Yuan Lin, Chien-Sung Tsai, Yi-Ting Tsai
BACKGROUND: Cardiac device-related infective endocarditis is an uncommon but potentially fatal complication. Therefore, cardiac devices should be removed as soon as a device-related infection is suspected. CASE REPORT: A 56-year-old male with a history of arrhythmogenic right ventricular dysplasia with implantable cardioverter-defibrillators (ICDs) 7 years earlier and re-implantation of ICDs due to dysfunction 18 months ago presented with erosion of the ICD pocket with Pseudomonas bacteremia...
July 2017: Acta Cardiologica Sinica
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