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https://www.readbyqxmd.com/read/29145323/the-effectiveness-of-2-consecutive-intra-articular-polydeoxyribonucleotide-injections-compared-with-intra-articular-triamcinolone-for-hemiplegic-shoulder-pain-a-strobe-complaint-retrospective-study
#1
Donghwi Park, Kwang Jae Yu, Ju Young Cho, Seung Beom Woo, Junu Park, Zeeihn Lee, Jong Min Kim
The aim of this study was to investigate the effects of intra-articular injection of polydeoxyribonucleotide (PDRN), compared with intraarticular triamcinolone (TA) injection, in subacute stroke patients with hemiplegic shoulder pain (HSP).Participants were subacute stroke patients with HSP who had undergone 2 consecutive intra-articular injections of TA or PDRN.Numeric rating scale (NRS) and passive range of motion (PROM) of hemiplegic shoulder were evaluated until 4 weeks after 2nd injection.In the results, there were significant improvements in all PROM measures 2 weeks after the second injection, compared with pre-injection results, in both groups (P < ...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29138074/outcome-of-transforaminal-epidural-steroid-injection-according-to-the-severity-of-cervical-foraminal-stenosis
#2
Min Son Kim, Dong Gyu Lee, Min Cheol Chang
BACKGROUND CONTEXT: Cervical transforaminal epidural steroid injection (TFESI) is considered one of the most effective treatments for radicular pain induced by cervical foraminal stenosis. PURPOSE: To evaluate the treatment outcome of TFESI according to the severity of cervical foraminal stenosis DESIGN: Retrospective study. PATIENT SAMPLE: Fifty-three patients with cervical radiculopathy due to cervical foraminal stenosis. OUTCOME MEASURES: Pain intensity was evaluated using a numeric rating scale (NRS) at pretreatment, 2 weeks, and 1, 2, and 3 months after TFESI...
November 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29137582/the-effectiveness-of-regional-anaesthesia-before-and-after-the-introduction-of-a-dedicated-regional-anaesthesia-service-incorporating-a-block-room
#3
A Chin, L Heywood, P Iu, A M Pelecanos, M J Barrington
Dedicated regional anaesthesia services incorporating block rooms and/or block teams may facilitate theatre efficiency and improve training in regional anaesthesia. Currently, it is unknown if a dedicated regional anaesthesia service improves the effectiveness of regional anaesthesia. In November 2013, the Royal Brisbane and Women's Hospital established a dedicated regional anaesthesia service comprising a block team and a block room. Pre-intervention (conventional model of care) registry data was retrospectively compared with post-intervention (dedicated regional anaesthesia service) audit data, with regard to pain and opioid requirement in the post-anaesthesia care unit (PACU)...
November 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29135493/relationship-between-postoperative-pain-and-overall-30-day-complications-in-a-broad-surgical-population-an-observational-study
#4
Regina L M van Boekel, Michiel C Warlé, Renske G C Nielen, Kris C P Vissers, Rob van der Sande, Ewald M Bronkhorst, Jos G C Lerou, Monique A H Steegers
OBJECTIVE: The aim of this study was to establish the relationship between postoperative pain and 30-day postoperative complications. BACKGROUND: Only scarce data are available on the association between postoperative pain and a broad range of postoperative complications in a large heterogeneous surgical population. METHODS: Having postoperative pain was assessed in 2 ways: the movement-evoked pain score on the Numerical Rating Scale (NRS-MEP) and the patients' opinion whether the pain was acceptable or not...
November 13, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29133161/the-efficacy-of-high-volume-of-local-infiltration-analgesia-for-postoperative-pain-relief-after-total-hip-arthroplasty-under-general-anaesthesia-a-randomised-controlled-trial
#5
Saskia Titman, Ami Hommel, Igor Dobrydnjov, Anders Johansson
BACKGROUND AND AIM: Research regarding patients undergoing total hip arthroplasty (THA) has shown no significant difference in postoperative pain with or without the use of local infiltration analgesia (LIA). The aim was to evaluate whether intra-operative LIA with Ropivacaine in patients undergoing THA under general anaesthesia reduces postoperative pain. METHOD: A randomised, placebo-controlled trial. Forty patients undergoing elective primary THA under general anaesthesia were allocated to an intervention group (RG) who received 150 ml of LIA or a placebo group (CG) who received 150 ml of saline solution...
October 31, 2017: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/29129079/macroscopic-assembly-of-gold-nanorods-into-superstructures-with-controllable-orientations-by-anisotropic-affinity-interaction
#6
Yun Rong, Liping Song, Peng Si, Lei Zhang, Xuefei Lu, Jiawei Zhang, Zhihong Nie, Youju Huang, Tao Chen
2D or 3D highly ordered arrays of anisotropic nanoparticles provide attracting properties that are highly desired by industry. Traditional assembly method such as evaporation usually produces the nanostructure arrays only up to milimeter scale with poor control of nanoparticle orientation, making them hardly applicable for industrial needs. Here we report a facile method to assemble centimeter-scale gold nanorod (Au NR) arrays with highly controlled nanoparticle orientation and high reproducibility. We selectively functionalized the transverse or longitudinal facets of the Au NRs with polyethylene glycol (PEG) molecules and utilized the interfacial polymeric affinity between the PEG domains on Au NRs and the PEGylated substrate to achieve the anisotropic self-assembly...
November 11, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29126259/an-open-label-study-of-sufentanil-sublingual-tablet-30%C3%A2-mcg-in-patients-with-postoperative-pain
#7
Jacob L Hutchins, David A Leiman, Harold S Minkowitz, Maurice Jove, Karen P DiDonato, Pamela P Palmer
Objective: To evaluate sufentanil sublingual tablet 30 mcg (SST 30 mcg) for postoperative pain in an older patient population with comorbidities. Design: Multicenter, open-label, single-arm study. Setting: Nine hospitals across the United States. Subjects: Adults aged ≥40 years who had undergone a surgical procedure. Methods: Patients with a postoperative pain intensity score ≥4 on an 11-point numeric rating scale (NRS) were allowed to enter the study and receive SST 30 mcg as requested for pain (minimum 60-minute redosing interval) over the 12-hour study period...
November 3, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29123622/retrospective-analysis-of-the-financial-break-even-point-for-intrathecal-morphine-pump-use-in-korea
#8
Eun Kyoung Kim, Ji Yeon Shin, Anyela Marcela Castañeda, Seung Jae Lee, Hyun Kyu Yoon, Yong Chul Kim, Jee Youn Moon
Background: The high cost of intrathecal morphine pump (ITMP) implantation may be the main obstacle to its use. Since July 2014, the Korean national health insurance (NHI) program began paying 50% of the ITMP implantation cost in select refractory chronic pain patients. The aims of this study were to investigate the financial break-even point and patients' satisfaction in patients with ITMP treatment after the initiation of the NHI reimbursement. Methods: We collected data retrospectively or via direct phone calls to patients who underwent ITMP implantation at a single university-based tertiary hospital between July 2014 and May 2016...
October 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/29122372/sufentanil-sublingual-tablet-30mcg-for-moderate-to-severe-acute-pain-in-the-emergency-department
#9
James R Miner, Zubaid Rafique, Harold S Minkowitz, Karen P DiDonato, Pamela P Palmer
BACKGROUND: Pharmacological properties of the sufentanil sublingual tablet 30mcg (SST 30mcg) could offer potential analgesic advantages in settings requiring noninvasive, acute pain management. The feasibility of using SST 30mcg for moderate-to-severe pain management in the emergency department (ED) was evaluated. METHODS: This open-label, multicenter feasibility study included patients aged ≥18years who presented to the ED with moderate-to-severe pain (≥4 on the numeric rating scale of pain intensity (NRS); opioid-tolerant patients were excluded...
October 31, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29121286/prediction-of-persistent-post-surgery-pain-by-preoperative-cold-pain-sensitivity-biomarker-development-with-machine-learning-derived-analysis
#10
J Lötsch, A Ultsch, E Kalso
Background: To prevent persistent post-surgery pain, early identification of patients at high risk is a clinical need. Supervised machine-learning techniques were used to test how accurately the patients' performance in a preoperatively performed tonic cold pain test could predict persistent post-surgery pain. Methods: We analysed 763 patients from a cohort of 900 women who were treated for breast cancer, of whom 61 patients had developed signs of persistent pain during three yr of follow-up...
October 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29117299/high-vs-low-dose-corticosteroid-injection-in-the-treatment-of-adhesive-capsulitis-with-severe-pain-a-randomized-controlled-double-blind-study
#11
Kyou Hyun Kim, Jong Wook Park, Sang Jun Kim
Objective: To compare the degree of pain relief between high-dose (40 mg of triamcinolone acetonide) and low-dose (20 mg of triamcinolone acetonide) corticosteroid injections in patients with severe pain due to adhesive capsulitis. Design: A prospective, randomized, double-blind, dose-comparative study. Subjects: A total of 32 patients who were diagnosed with adhesive capsulitis and who expressed severe pain intensity, 8 or more points on a numeric rating scale (NRS)...
October 7, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29114833/effect-of-a-single-dose-of-oral-opioid-and-nonopioid-analgesics-on-acute-extremity-pain-in-the-emergency-department-a-randomized-clinical-trial
#12
Andrew K Chang, Polly E Bijur, David Esses, Douglas P Barnaby, Jesse Baer
Importance: The choice of analgesic to treat acute pain in the emergency department (ED) lacks a clear evidence base. The combination of ibuprofen and acetaminophen (paracetamol) may represent a viable nonopioid alternative. Objectives: To compare the efficacy of 4 oral analgesics. Design, Settings, and Participants: Randomized clinical trial conducted at 2 urban EDs in the Bronx, New York, that included 416 patients aged 21 to 64 years with moderate to severe acute extremity pain enrolled from July 2015 to August 2016...
November 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29114415/effect-of-low-dose-remifentanil-on-postoperative-pain-relief-and-heart-rate-variability-in-post-anaesthesia-care-unit
#13
Shynma Uchida, Yuji Kadoi, Shigeru Saito
Objective: Several reports have shown the negligible adverse effects of low-dose remifentanil on the autonomic nervous system. We propose that the administration of low-dose remifentanil would be beneficial without adverse respiratory and hemodynamic effects. This study aimed to examine the effects of low-dose remifentanil on postoperative pain relief and heart rate variability (HRV) after surgery. Methods: In total, 20 patients, who underwent breast cancer surgery, were analysed for HRV in the post-anaesthesia care unit (PACU)...
October 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29112942/acupuncture-for-primary-dysmenorrhea-a-meta-analysis-of-randomized-controlled-trials
#14
Tong Liu, Jia-Ni Yu, Bing-Yan Cao, Yuan-Yuan Peng, Yu-Pei Chen, Li Zhang
Context • Primary dysmenorrhea (PD) is one of the most common complaints among young women. Acupuncture has been widely applied as a therapeutic modality in China and abroad for PD; however, the evidence for its benefits is still not convincing. Objective • The study intended to conduct a systematic review of randomized, controlled trials (RCTs) to evaluate the evidence regarding the use of acupuncture in treating PD. Design • The research team retrieved reports for RCTs published in 7 databases from their inception to March 2016, with no language restrictions: PubMed, Medline, Embase, the Cochrane Central Register of Controlled Trials, the Chinese National Knowledge Infrastructure database, the Chinese Biomedical database, and the Wanfang database...
November 7, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29109886/radiofrequency-targeted-vertebral-augmentation-case-report-of-a-patient-with-7-osteoporotic-vertebral-fractures-in-a-variant-of-osteogenesis-imperfecta
#15
Leonard Westermann, Peer Eysel, Marvin Simons, Kourosh Zarghooni
Introduction: Radiofrequency-targeted vertebral augmentation (RF-TVA) is a recognized treatment for painful compression fractures. RF-TVA in a patient with multiple compression fractures due to type I osteogenesis imperfecta (OI) has not been previously reported. Case Presentation: A 54-year-old patient with type I OI is presented with a segmental thoracic hyperkyphosis and 7 recent vertebral compression fractures. Because of persistent severe thoracolumbar back pain despite conservative therapy, RF-TVA was indicated...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29109298/severity-of-neuropathy-is-associated-with-long-term-spinal-cord-stimulation-outcome-in-painful-diabetic-peripheral-neuropathy-five-year-follow-up-of-a-prospective-two-center-clinical-trial
#16
Maarten van Beek, José W Geurts, Rachel Slangen, Nicolaas C Schaper, Catharina G Faber, Elbert A Joosten, Carmen D Dirksen, Robert T van Dongen, Sander M J van Kuijk, Maarten van Kleef
OBJECTIVE: Evidence from prospective studies for long-term treatment efficacy of spinal cord stimulation (SCS) in painful diabetic polyneuropathy (PDPN) is not available. We report prospective data on the effect of SCS on pain ratings, treatment success and failure, and complications during a 5-year follow-up in patients with PDPN. RESEARCH DESIGN AND METHODS: Patients with PDPN (n = 48) were included in this prospective multicenter study. The Michigan Diabetic Neuropathy Score (MDNS) was used to assess the severity of neuropathy...
November 6, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29104684/effect-of-flunarizine-on-serum-glutamate-levels-and-its-correlation-with-headache-intensity-in-chronic-tension-type-headache-patients
#17
Khairul Putra Surbakti, Hasan Sjahrir, Rosita Juwita-Sembiring, Erna Mutiara
BACKGROUND: Some of the excitatory neurotransmitters including glutamate have been suggested to be involved in headache pathophysiology. To our knowledge, there is a lack of publication about flunarizine efficacy in chronic tension-type headache (CTTH) treatments and the roles of glutamate in CTTH pathophysiology. AIM: This study aimed to investigate the flunarizine effect on serum levels of glutamate and its correlation with headache intensity based on the Numeric Rating Scale for pain (NRS) scores in CTTH patients...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104660/target-controlled-infusion-of-propofol-and-remifentanil-combined-with-dexmedetomidine-reduces-functional-endoscopic-sinus-surgery-bleeding
#18
Deng-Feng Ding, Li-Fang Wu, Ping Wang, Yuan-Xu Jiang, Yao-Wen Luo, Zhong-Liang Dai, Xue-Ping Zhang, Ya-Li Li
The aim of the present study was to investigate the effects of target-controlled infusion (TCI) of propofol and remifentanil combined with dexmedetomidine on functional endoscopic sinus surgery (FESS) bleeding and surgical field. 62 patients scheduled to undergo FESS were randomly divided into experimental group (intravenous 0.5 µg kg(-1) h(-1) dexmedetomidine after 0.5 µg kg(-1) bolus within 15 min until the end of surgery) or control group (intravenous saline administration at the same dose). All patients underwent endotracheal intubation under general anesthesia with TCI of propofol and remifentanil for anesthesia induction and maintenance...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29103436/effectiveness-of-pulsed-electromagnetic-field-for-pain-caused-by-placement-of-initial-orthodontic-wire-in-female-orthodontic-patients-a-preliminary-single-blind-randomized-clinical-trial
#19
Jin-Gon Jung, Jae Hyun Park, Sang-Cheol Kim, Kyung-Hwa Kang, Jin-Hyoung Cho, Jin-Woo Cho, Na-Young Chang, R Curtis Bay, Jong-Moon Chae
INTRODUCTION: The purpose of this 2-arm parallel trial was to assess the effects of pulsed electromagnetic field (PEMF) on the reduction of pain caused by initial orthodontic tooth movement. METHODS: Thirty-three female patients (mean age, 16.8 ± 3.8 years) who began orthodontic treatment using fixed appliances were examined. In the pilot study, male patients were less likely to use the PEMF device (epatchQ; Speed Dental, Seoul, Korea) and answer a survey consistently, so eligibility criteria were female patients who were periodontally and systemically healthy at the initiation of treatment and had no history of dental pain in the prior 2 weeks or who used no medications (anti-inflammatory or analgesic drugs) during the experiment period...
November 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29101777/percutaneous-electrical-nerve-stimulation-for-chronic-knee-pain-a-randomized-sham-controlled-trial
#20
Da-Peng He, Jun Zhang, Zheng-Fa Bai
Context • Anti-inflammatory drugs are often used to treat chronic knee pain (CKP), but their long-term use is associated with decreased effectiveness and numerous side effects. Complementary and alternative medicine provides additional treatments for the condition, including percutaneous electrical nerve stimulation (PENS). However, the benefits of PENS for treatment of CKP are still controversial. Objective • The study intended to assess the effects and safety of PENS for treatment of CKP. Methods • This study was a 2-arm, randomized, sham-controlled trial...
November 4, 2017: Alternative Therapies in Health and Medicine
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