keyword
MENU ▼
Read by QxMD icon Read
search

Onset puberty

keyword
https://www.readbyqxmd.com/read/28533118/white-matter-alterations-at-pubertal-onset
#1
Sila Genc, Marc L Seal, Thijs Dhollander, Charles B Malpas, Philip Hazell, Timothy J Silk
Recent neurodevelopmental research supports the contribution of pubertal stage to local and global grey and white matter remodelling. Little is known, however, about white matter microstructural alterations at pubertal onset. This study investigated differences in white matter properties between pre-pubertal and pubertal children using whole brain fixel-based analysis (FBA) of the microscopic density and macroscopic cross-section of fibre bundles. Diffusion-weighted imaging data were acquired for 74 typically developing children (M=10...
May 19, 2017: NeuroImage
https://www.readbyqxmd.com/read/28532840/effect-of-breed-plane-of-nutrition-and-age-on-growth-scrotal-development-metabolite-concentrations-and-on-systemic-gonadotropin-and-testosterone-concentrations-following-a-gnrh-challenge-in-young-dairy-bulls
#2
C J Byrne, S Fair, A M English, C Urh, H Sauerwein, M A Crowe, P Lonergan, D A Kenny
The onset of puberty in the bull is regulated by the timing of early GnRH pulsatility release from the hypothalamus, which has been demonstrated to be affected by plane of nutrition during calf-hood. The aim of this study was to determine the effect of plane of nutrition on growth rate, scrotal development, metabolite concentrations and exogenous gonadotrophin (GnRH) induced release of luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone (TT) in pre-pubertal bulls of two contrasting dairy breeds...
July 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28516749/international-comparison-of-adult-height-in-children-with-growth-hormone-deficiency-and-limitations-of-growth-hormone-treatment-in-japan
#3
Toshiaki Tanaka
The approved therapeutic dose of growth hormone (GH) for growth hormone deficiency (GHD) varies depending on the country. Japan has the lowest therapeutic dose globally, with a single dose of 0.175 mg/kg/week. GH treatment for GHD is considered as a replacement therapy and in fact, a dose of 0.175 mg/kg/week is slightly higher than GH secretion in prepubertal healthy children but nearly the same as that of pubertal children. Although the same growth rate as that of healthy children is expected in response to replacement therapy, the catch-up growth observed for the first 1 to 2 years of GH treatment was misinterpreted as an effect of the GH replacement therapy...
March 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28508614/methods-for-rating-sexual-development-in-girls
#4
Vincenzo De Sanctis, Ihab Zaki Elhakim, Ashraf T Soliman, Heba Elsedfy, Rania Elalaily, Giuseppe Millimaggi
Sexual maturity rating (SMR) is important in population studies and in clinical care. Pubertal staging allows doctors to assess the maturation of adolescents to correlate several pubertal phenomena such as age at menarche, growth spurt and final height, to advise and manage patients appropriately and to have sensitive "sensors" of the effects of environmental exposure on human populations. The commonly used markers of the timing of female puberty are thelarche and menarche. Appearance of the breast bud is the first indicator of puberty onset in 90% of girls...
September 2016: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28503109/parental-reports-of-prodromal-psychopathology-in-pediatric-bipolar-disorder
#5
Mariely Hernandez, Ciro Marangoni, Marie C Grant, Jezelle Estrada, Gianni L Faedda
OBJECTIVES: Early psychopathology in children diagnosed with Bipolar Disorder (BD) remains poorly characterized. Parental retrospective reports provide helpful details on the earliest manifestations and their evolution over time. These symptoms occur early in the course of BD, often before a formal diagnosis is made and/or treatment is implemented, and are of great importance to early recognition and prevention. METHODS: Parents of pre-pubertal children and adolescents with DSM-IV diagnoses of BD attending an outpatient mood disorders clinic provided retrospective ratings of 37 symptoms of child psychopathology...
April 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28501545/betamethasone-causes-intergenerational-reproductive-impairment-in-male-rats
#6
Cibele Dos Santos Borges, Taina Louise Pacheco, Katiussia Pinho da Silva, Fábio Henrique Fernandes, Mary Gregory, André Sampaio Pupo, Daisy Maria F Salvadori, Daniel G Cyr, Wilma De G Kempinas
Prenatal betamethasone (BM) exposure in rats negatively impacts sperm quality and male fertility. Studies have shown that BM can cause multi-generational effects on the pituitary-adrenal-axis of rats. The objective of this study was to assess the reproductive development and fertility of male rats (F2) whose fathers (F1) were exposed to BM (0.1mg/kg) on gestational days 12, 13, 18 and 19. In F2 rats, there was a significant reduction in body weights of the BM-treated group at PND 1 as well as delayed onset of puberty, and decreases in FSH levels, Leydig cell volume, sperm number and motility, seminal vesicle contractility and ejaculated volume...
May 10, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28501319/association-of-pyrethroids-exposure-with-onset-of-puberty-in-chinese-girls
#7
Xiaoqing Ye, Wuye Pan, Yuehao Zhao, Shilin Zhao, Yimin Zhu, Weiping Liu, Jing Liu
Pyrethroids, a class of ubiquitous insecticides, have been considered as endocrine-disrupting chemicals (EDCs). Female animal studies suggested that early-life pyrethroids exposure might delay puberty onset. However, it remains unclear whether this association applies to human populations. A total of 305 girls at the ages of 9-15 years old were recruited in Hangzhou, China in this study. The concentration of the common metabolite of pyrethroids, 3-phenoxybenzoic acid (3-PBA), was analyzed in urine samples to reflect the exposure level of pyrethroids...
May 10, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28500430/postnatal-feeding-with-high-fat-diet-induces-obesity-and-precocious-puberty-in-c57bl-6j-mouse-pups-a-novel-model-of-obesity-and-puberty
#8
Rahim Ullah, Yan Su, Yi Shen, Chunlu Li, Xiaoqin Xu, Jianwei Zhang, Ke Huang, Naveed Rauf, Yang He, Jingjing Cheng, Huaping Qin, Yu-Dong Zhou, Junfen Fu
Childhood obesity and obesity-related metabolic complications are induced by a high-fat postnatal diet. The lack of a suitable animal model, however, remains a considerable challenge in obesity studies. In the current study, we provided high-fat diet (HFD) to dams during lactation and to pups after weaning. We also developed a novel model of C57BL/6J mouse pups with HFD-induced postnatal obesity. Results showed that feeding with HFD induces fat deposition and obesity in pups. Furthermore, HFD more potently increased the body weight (BW) of male than female pups...
May 13, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28499829/characteristics-of-traditional-chinese-medicine-usage-in-children-with-precocious-puberty-a-nationwide-population-based-study
#9
Yi-Chun Lin, Tung-Ti Chang, Husan-Ju Chen, Chung-Hsing Wang, Mao-Feng Sun, Hung-Rong Yen
ETHNOPHARMACOLOGICAL RELEVANCE: Precocious puberty (PP) occurs in children with the early onset of pubertal development leading to physical and psychological problems. Current medical treatment is expensive and has its side effects. However, little is known about the utilization of traditional Chinese medicine (TCM) among patients with PP. To characterize the application of TCM among these patients, we conducted a nationwide population-based study. MATERIALS AND METHODS: We used the Taiwanese National Health Insurance Research Database (NHIRD), to perform a nationwide population-based study...
May 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28480655/effects-of-adrenal-androgen-levels-on-bone-age-advancement-in-prepubertal-children-using-the-ewha-birth-and-growth-cohort-study
#10
Jung Hyun Kwon, Hye Ah Lee, Young Ju Kim, Hwayoung Lee, Eun Ae Park, Su Jin Cho, Hye Sun Gwak, Eunhee Ha, Hyesook Park, Hae Soon Kim
Bone age (BA) advancement in prepubertal children may be associated with earlier onset of puberty and obesity. This study aimed to define the effects of adrenal androgen levels on the advancement of BA in prepubertal children, independent of obesity. During July and August 2011, we examined BA in 200 prepubertal children aged 7-9 years who were part of the Ewha Birth & Growth Cohort Study. BA was assessed by the Greulich-Pyle method. An index of BA advancement was calculated as the ratio of BA to chronological age (CA) (BA/CA), and this ratio was classified into 3 tertiles...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28478948/final-height-and-intrauterine-growth-retardation
#11
Maïthé Tauber
Approximately 10% of small for gestational age (SGA) children maintain a small body size throughout childhood and often into adult life with a decreased pubertal spurt. Growth hormone (GH) therapy increases short-term growth in a dose-dependent manner and adult height had now been well documented. Shorter children might benefit from a higher dose at start (50μg/kg/day). The response to GH treatment was similar for both preterm and term short SGA groups and the effect of GH treatment on adult height showed a wide variation in growth response...
May 4, 2017: Annales D'endocrinologie
https://www.readbyqxmd.com/read/28478668/relationships-of-pyrethroids-exposure-with-gonadotropins-levels-and-pubertal-development-in-chinese-boys
#12
Xiaoqing Ye, Wuye Pan, Shilin Zhao, Yuehao Zhao, Yimin Zhu, Jing Liu, Weiping Liu
Although an acceleration of male pubertal development has been observed, precisely which endocrine-disrupting chemicals (EDCs) might contribute to the advancing onset of puberty in boys remains unclear. Here, pyrethroids, a class of widely used insecticides that have been as considered as EDCs, are proposed as new environmental risk factors. In this study, 463 boys at the age of 9-16 years old were recruited in Hangzhou, Zhejiang, China. The common metabolites of pyrethroids, 3-phenoxybenzoic acid (3-PBA) and 4-fluro-3-phenoxybenzoic acid (4-F-3-PBA), as well as the gonadotropins, including luteinizing hormone (LH) and follicle-stimulating hormone (FSH), were analyzed in urine samples...
May 8, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28475285/involvement-of-neurone-glia-neurone-neurone-communications-via-gap-junctions-in-synchronised-activity-of-kndy-neurones
#13
K Ikegami, S Minabe, N Ieda, T Goto, A Sugimoto, S Nakamura, N Inoue, S Oishi, A D Maturana, M Sanbo, M Hirabayashi, K-I Maeda, H Tsukamura, Y Uenoyama
Pulsatile secretion of the gonadotropin-releasing hormone (GnRH)/luteinizing hormone is indispensable for puberty onset and reproductive activities at adulthood in mammalian species. A cohort of neurones expressing three neuropeptides, kisspeptin, encoded by Kiss1 gene, neurokinin B (NKB) and dynorphin A, localised in the hypothalamic arcuate nucleus (ARC), so-called KNDy neurones, are a putative intrinsic source of the GnRH pulse generator. Synchronous activity among KNDy neurones is thought to be required for pulsatile GnRH secretion...
May 5, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/28474986/ovarian-hormones-age-and-pubertal-development-and-their-association-with-days-of-headache-onset-in-girls-with-migraine-an-observational-cohort-study
#14
Vincent T Martin, Janelle R Allen, Timothy T Houle, Scott W Powers, Marielle A Kabbouche, Hope L O'Brien, Joanne Kacperski, Susan L LeCates, Shannon White, Polly Vaughan, Karen Mandell, Andrew D Hershey
Background Fifty-three percent of adolescent girls report headaches at the onset of menses, suggesting fluctuations of ovarian hormones trigger migraine during puberty. Aims To determine if urinary metabolites of estrogen and progesterone are associated with days of headache onset (HO) or severity in girls with migraine. Methods This was a pilot study and included 34 girls with migraine balanced across three age strata (pre-pubertal (8-11), pubertal (12-15), and post-pubertal (16-17) years of age). They collected daily urine samples and recorded the occurrence and severity of headache in a daily diary...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28464910/intracerebroventricular-injection-of-rfrp-3-delays-puberty-onset-and-stimulates-growth-hormone-secretion-in-female-rats
#15
Xinghui Han, Yuanyuan He, Gulan Zeng, Yonghong Wang, Wen Sun, Junchao Liu, Yanyan Sun, Jian Yu
BACKGROUND: Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadotropin in mammals. However, it is unclear whether RFRP-3 participates in regulating pubertal development. METHODS: This study investigated the functional significance and regulatory mechanism of hypothalamic RFRP-3 neuropeptide in the onset of puberty in young female rats...
May 2, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28458458/evaluation-of-growth-hormone-treatment-efficacy-in-short-japanese-children-born-small-for-gestational-age-five-year-treatment-outcome-and-impact-on-puberty
#16
Reiko Horikawa, Toshiaki Tanaka, Hiromi Nishinaga, Yoshihisa Ogawa, Susumu Yokoya
Some children born small for gestational age (SGA) have short stature and are at an increased risk of developing psychosocial or behavioral problems. Here we evaluated the efficacy of GH and its effects on the timing of pubertal onset in a 3-yr extension of our previous 2-yr (total 5 yr) multicenter, randomized, double-blind, parallel-group clinical trial of 65 short Japanese children born SGA. Patients received low or high doses of GH (0.033 or 0.067 mg/kg/day, respectively). Age at onset of puberty was not statistically different for male and female patients receiving high- or low-dose GH...
2017: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/28444173/tac1-signaling-is-required-for-sexual-maturation-and-responsiveness-of-gnrh-neurons-to-kisspeptin-in-the-male-mouse
#17
Caroline A Maguire, Yong Bhum Song, Min Wu, Silvia León, Rona S Carroll, Meenakshi Alreja, Ursula B Kaiser, Víctor M Navarro
The tachykinins substance P (SP) and neurokinin A (NKA) (Tac1) have emerged as novel regulators of kisspeptin/GnRH release. Recently, we documented that SP modulates reproductive function in the female mouse. Here, we extended this characterization to the male mouse. Tac1-/- male mice showed delayed puberty onset. They also presented significantly decreased expression levels of Pdyn (dynorphin) and Nos1 (nitric oxide synthase) in the mediobasal hypothalamus and elevated Gnrh1 levels. Unexpectedly, the response of Tac1-/- mice to central kisspeptin or senktide (neurokinin B receptor -NK3R- agonist) administration was significantly decreased compared with controls, despite the preserved ability of GnRH neurons to stimulate LH release as demonstrated by central NMDA administration, suggesting a deficit at the GnRH neuron level...
April 21, 2017: Endocrinology
https://www.readbyqxmd.com/read/28438528/molecular-characterization-of-kiss2-receptor-and-in-vitro-effects-of-kiss2-on-reproduction-related-gene-expression-in-the-hypothalamus-of-half-smooth-tongue-sole-cynoglossus-semilaevis
#18
Bin Wang, Quan Liu, Xuezhou Liu, Yongjiang Xu, Bao Shi
Kisspeptin (Kiss) and its receptor, KissR (previously known as GPR54), play a critical role in the control of reproduction and puberty onset in mammals. Additionally, a number of studies have provided evidence of the existence of multiple Kiss/KissR systems in teleosts, but the physiological relevance and functions of these kisspeptin forms (Kiss1 and Kiss2) still remain to be investigated. To this end, we examined the direct actions of Kiss2 on hypothalamic functions in the half-smooth tongue sole (Cynoglossus semilaevis), a representative species of the order Pleuronectiformes...
April 21, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28437358/integrated-multidimensional-maturity-assessments-predicting-the-high-risk-occurrence-of-peak-angle-velocity-during-puberty-in-progressive-female-idiopathic-scoliosis
#19
Benlong Shi, Saihu Mao, Leilei Xu, Xu Sun, Zezhang Zhu, Bangping Qian, Zhen Liu, Jack Chun Yiu Cheng, Yong Qiu
STUDY DESIGN: A consecutive and prospective longitudinal study. OBJECTIVE: To propose an integrated multidimensional maturity assessment that was designated as forming a reliable system precisely predicting the high-risk occurrence of peak angle velocity (PAV) in a group of progressive braced female idiopathic scoliosis (IS). SUMMARY OF BACKGROUND DATA: Scoliosis deterioration is believed to keep pace with the evolution of skeletal maturity during puberty...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28432332/involvement-of-gonadotropin-inhibitory-hormone-in-pubertal-disorders-induced-by-thyroid-status
#20
Mika Kiyohara, You Lee Son, Kazuyoshi Tsutsui
Thyroid disorders cause abnormal puberty, indicating interactions between the hypothalamus-pituitary-thyroid (HPT) and hypothalamus-pituitary-gonadal (HPG) axes, which are important in pubertal development. The hypothalamic gonadotropin-inhibitory hormone (GnIH) was shown to be decreased in the early prepubertal stage, suggesting the role of GnIH on pubertal onset. Here, we investigated whether thyroid dysfunction affects pubertal onset in female mice via GnIH regulation. Hypothyroidism showed delayed pubertal onset with increased GnIH expression and reduced pituitary-gonadal activity...
April 21, 2017: Scientific Reports
keyword
keyword
73468
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"