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Onset puberty

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https://www.readbyqxmd.com/read/28231067/the-association-of-peripubertal-serum-concentrations-of-organochlorine-chemicals-and-blood-lead-with-growth-and-pubertal-development-in-a-longitudinal-cohort-of-boys-a-review-of-published-results-from-the-russian-children-s-study
#1
Oleg Sergeyev, Jane S Burns, Paige L Williams, Susan A Korrick, Mary M Lee, Boris Revich, Russ Hauser
Organochlorine chemicals and lead are environmental exposures that have endocrine disrupting properties (EDCs) which interfere with many aspects of hormone action. Childhood and adolescence are windows of susceptibility for adverse health effects of EDCs. Our ongoing study, the Russian Children's Study (RCS), is one of the few longitudinal studies investigating the impact of EDCs on growth and puberty in boys. It is conducted in the historically contaminated city of Chapaevsk, in the Samara region. The study focuses on evaluating the associations of persistent organochlorine chemicals and lead with growth and pubertal timing...
February 23, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28229578/growth-and-pubertal-development-in-adolescent-male-wrestlers
#2
İbrahim E Pişkin, Mustafa Gümüş, Taner Bayraktaroğlu, Tevfik C Akalin, Faruk Yamaner
BACKGROUND: Adolescence is a crucial period for linear growth, and sports training during this time may have positive or negative effects on some physiological processes as growth. The purpose of this study was to evaluate the effects of intense training during somatic growth on the onset of puberty and growth development in adolescent wrestlers. METHODS: Fifty adolescent male wrestlers and twenty-one sedentary healthy male controls aged between 13-15 years were selected...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28225306/hydrocortisone-therapy-and-growth-trajectory-in-children-with-classical-congenital-adrenal-hyperplasia
#3
Carla Bizzarri, Nicola Improda, Chiara Maggioli, Donatella Capalbo, Silvia Roma, Ottavia Porzio, Mariacarolina Salerno, Marco Cappa
OBJECTIVE: Poor linear growth is one of the main concerns in children with congenital adrenal hyperplasia (CAH). We aimed to analyze factors affecting growth trajectory in children with classical CAH. METHODS: Clinical records of children followed from infancy up to the end of growth at two Italian tertiary referral hospitals were reviewed. Fifty-seven patients (31 males), treated with hydrocortisone and fludrocortisone only, were included. Clinical observations were divided into 3 groups: 0-2 years: 172 observations; from 2 years to puberty onset: 813 observations; after puberty onset: 527 observations...
February 22, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28216130/amphiregulin-as-a-novel-serum-marker-of-puberty-in-girls
#4
Frank M Biro, Susan M Pinney, Richard C Schwartz, Bin Huang, Ashley M Cattran, Sandra Z Haslam
OBJECTIVES: Amphiregulin is a member of the epidermal growth factor family. In breast tissue, amphiregulin is a mediator of estrogen and progesterone signaling. The objectives were to examine the relationship of amphiregulin levels during peripuberty with estrogen levels. METHODS: The participants in this analysis were a subset from a longitudinal study of pubertal maturation, the Breast Cancer and the Environment Research Program. They were recruited between ages six and seven...
February 16, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28215240/morningness-eveningness-correlates-with-sleep-time-quality-and-hygiene-in-secondary-school-students-a-multilevel-analysis
#5
Christian Vollmer, Konrad S Jankowski, Juan F Díaz-Morales, Heike Itzek-Greulich, Peter Wüst-Ackermann, Christoph Randler
At the onset of puberty, students shift their sleep to later hours, but school starts early. It is suggested that evening orientation and early school start times do not go well together. Therefore, the aim of this study was to investigate sleep problems in adolescence, and it was expected that the adolescents' eveningness orientation is associated with many sleep-related problems. Students of secondary education (n = 3201; mean = 13.8 ± 1.8 years) filled out a self-report questionnaire containing measures of morningness-eveningness, sleep time (midpoint of sleep, social "jetlag"), sleep length (on schooldays and on weekends), sleep quality, and sleep hygiene as well as questions on electronic screen media use...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28211546/differential-effects-of-hormones-on-cellular-metabolism-in-keratoconus-in-vitro
#6
Tina B McKay, Jesper Hjortdal, Henrik Sejersen, Dimitrios Karamichos
Keratoconus (KC) is a corneal thinning disease with an onset commonly immediately post-puberty and stabilization by 40 to 50 years of age. The role of hormones in regulating corneal tissue structure in homeostatic and pathological conditions is unknown. Our group recently linked altered hormone levels to KC. Our current study sought to investigate and delineate the effects of exogenous hormones, such as androgen, luteotropin, and estrogen, on corneal stroma bioenergetics. We utilized our established 3D in vitro model to characterize the effects of DHEA, prolactin, 17β-estradiol on insulin-growth factor-1 and -2 (IGF-1, -2) signaling and metabolic function in primary corneal fibroblasts from healthy controls (HCFs) and KC patients (HKCs)...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28203334/assessment-of-sexual-maturation-among-girls-with-special-needs-in-tehran-iran
#7
Hosein Shabani Mirzaee, Asieh Mosallanejad, Ali Rabbani, Aria Setoodeh, Farzaneh Abbasi, Fatemeh Sayarifard, Amir Hosein Memari
BACKGROUND: There is limited data on sexual maturation among girls with intellectual, sensory, or physical disabilities. OBJECTIVES: The present cross-sectional study was conducted to assess the sexual maturation of girls with these disabilities in special schools. METHODS: In this cross-sectional study, we evaluated the onset and progression of sexual maturation in 642 six to 18-year-old girls with intellectual, sensory, or physical disabilities from special schools in Tehran...
October 2016: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/28196477/screening-and-evaluating-of-long-noncoding-rnas-in-the-puberty-of-goats
#8
Xiaoxiao Gao, Jing Ye, Chen Yang, Kaifa Zhang, Xiumei Li, Lei Luo, Jianping Ding, Yunsheng Li, Hongguo Cao, Yinghui Ling, Xiaorong Zhang, Ya Liu, Fugui Fang, Yunhai Zhang
BACKGROUND: Long noncoding RNAs (lncRNAs) are involved in regulating animal development, however, their function in the onset of puberty in goats remain largely unexplored. To identify the genes controlling the regulation of puberty in goats, we measured lncRNA and mRNA expression levels from the hypothalamus. RESULTS: We applied RNA sequencing analysis to examine the hypothalamus of pubertal (case; n = 3) and prepubertal (control; n = 3) goats. Our results showed 2943 predicted lncRNAs, including 2012 differentially expressed lncRNAs, which corresponded to 5412 target genes...
February 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28190662/prospective-ultrasonographic-and-endocrine-predictors-of-spermatogenic-onset-in-ram-lambs
#9
Pawel M Bartlewski, Jennifer L Giffin, Olutobi A Oluwole, Ann C Hahnel
The objective of this study was to examine testicular ultrasonographic characteristics and endocrine profiles in prepubescent ram lambs for correlations with the age at first detection of elongated spermatids (ESt age). Bi-weekly ultrasound examinations and weekly testicular biopsies began at 10 weeks of age or at the time that testicular volume reached 15cm(3), and continued until 1-2 weeks after Est's were first detected by histological examination of testicular biopsies in twenty-two spring-born Rideau Arcott×Polled Dorset lambs...
February 6, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28183093/putative-effects-of-obesity-on-linear-growth-and-puberty%C3%A2
#10
Shlomit Shalitin, Wieland Kiess
Childhood obesity is a major public health problem that has grown to epidemic proportions throughout the world. Obesity is influenced by genetic and environmental factors. The nutritional status plays an important role in growth and body weight regulation. Excess adiposity during childhood can affect the process of growth and puberty. Obese children are frequently tall for their age, with accelerated epiphyseal growth plate maturation despite low growth hormone levels. Several regulatory hormones may affect the process of linear growth in the constellation of obesity, as high levels of insulin and leptin are observed in obese children...
February 9, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28174478/scoliosis-in-adulthood-a-case-with-untreated-early-onset-scoliosis-presenting-at-the-age-of-76-years
#11
Hans-Rudolf Weiss
[Purpose] Untreated early-onset scoliosis may eventually progress to more than 90° after growth, cause severe health problems, and increase chance of mortality. Therefore, surgical intervention is often indicated prior to the development of a life-threatening deformity. This case report aims to reveal how a 76-year-old male patient with curves exceeding 110° is functioning with minimal difficulty. [Subject and Methods] The patient, who has never had surgical intervention for scoliosis, can perform his everyday activities...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28173872/childhood-body-size-and-pubertal-timing-in-relation-to-adult-mammographic-density-phenotype
#12
Minouk J Schoemaker, Michael E Jones, Steven Allen, Jean Hoare, Alan Ashworth, Mitch Dowsett, Anthony J Swerdlow
BACKGROUND: An earlier age at onset of breast development and longer time between pubertal stages has been implicated in breast cancer risk. It is not clear whether associations of breast cancer risk with puberty or predictors of onset of puberty, such as weight and height, are mediated via mammographic density, an important risk factor for breast cancer. METHODS: We investigated whether childhood body size and pubertal timing and tempo, collected by questionnaire, are associated with percentage and absolute area mammographic density at ages 47-73 years in 1105 women recruited to a prospective study...
February 7, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28170387/early-growth-faltering-in-post-institutionalized-youth-and-later-anthropometric-and-pubertal-development
#13
Brie M Reid, Bradley S Miller, Lorah D Dorn, Christopher Desjardins, Bonny Donzella, Megan Gunnar
BACKGROUND: Early life adversity that increases the risk of growth stunting is hypothesized to increase the risk of obesity and, in girls, early onset puberty. This hypothesis was tested in children adopted from orphanages. METHODS: Post-institutionalized (PI) youth were compared with youth reared in comparable families (non-adopted; NA) on height, weight, pubertal stage, and fat mass (127 PI, 80 female; 156 NA, 85 female, aged 7-14 years). Anthropometrics at adoption were obtained from first US clinic visits...
February 7, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28168696/adapting-and-applying-the-phenice-1969-adult-morphological-sex-estimation-technique-to-subadults
#14
Alexandra R Klales, Tesa L Burns
This research evaluated whether adult morphological sex estimation methods of the innominate could be adapted and applied to subadults. The subpubic concavity, described by Phenice (1969) and revised by Klales et al. (2012), was modified for use with subadults. Two observers scored radiographic images from the PATRICIA database of 334 individuals of both sexes aged between 1.19 and 20.47 years. Score frequencies shifted from score 2 (straight) to higher frequencies of score 3 (convexity) in males and score 1 (concavity) in females with increasing age...
February 6, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28166807/non-invasive-optical-spectroscopic-monitoring-of-breast-development-during-puberty
#15
Lothar Lilge, Mary Beth Terry, Jane Walter, Dushanthi Pinnaduwage, Gord Glendon, Danielle Hanna, Mai-Liis Tammemagi, Angela Bradbury, Saundra Buys, Mary Daly, Esther M John, Julia A Knight, Irene L Andrulis
BACKGROUND: Tanner staging (TS), a five-stage classification indicating no breast tissue (TS1) to full breast development (TS5), is used both in health research and clinical care to assess the onset of breast development (TS2) and duration in each stage. Currently, TS is measured both visually and through palpation but non-invasive methods will improve comparisons across settings. METHODS: We used optical spectroscopy (OS) measures from 102 girls at the Ontario site of the LEGACY girls study (average age 12 years, range 10...
February 6, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28153577/molecular-characterization-and-functional-analysis-of-pituitary-gnrh-receptor-in-a-commercial-scombroid-fish-chub-mackerel-scomber-japonicus
#16
Sanny David Pacheco Lumayno, Hirofumi Ohga, Sethu Selvaraj, Mitsuo Nyuji, Akihiko Yamaguchi, Michiya Matsuyama
The gonadotropin-releasing hormone (GnRH) is essential during pubertal onset, for its regulation of the synthesis and release of pituitary gonadotropins. Its action is mediated by GnRH receptors (GnRHRs) in the pituitary gonadotrophs. Our previous study demonstrated that the chub mackerel brain expresses three GnRH forms (gnrh1, gnrh2, and gnrh3), and that only GnRH1 neurons innervate anterior pituitary regions. Furthermore, chub mackerel gnrh1 mRNA exhibited a significant increase at pubertal onset. The present study aimed to isolate the functional GnRHR form involved in chub mackerel puberty...
January 30, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28141713/developmental-regression-depression-and-psychosocial-stress-in-an-adolescent-with-down-syndrome
#17
David S Stein, Kerim M Munir, Andrea J Karweck, Emily J Davidson, Martin T Stein
Kristen is a 13-year-old girl with Down syndrome (DS) who was seen urgently with concerns of cognitive and developmental regression including loss of language, social, and toileting skills. The evaluation in the DS clinic focused on potential medical diagnoses including atlantoaxial joint instability, vitamin deficiency, obstructive sleep apnea (OSA), and seizures. A comprehensive medical evaluation yielded only a finding of moderate OSA. A reactive depression was considered in association with several psychosocial factors including moving homes, entering puberty/onset of menses, and classroom change from an integrated setting to a self- contained classroom comprising unfamiliar peers with behavior challenges...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28141708/an-8-year-old-biological-female-who-identifies-herself-as-a-boy-perspectives-in-primary-care-and-from-a-parent
#18
Leah Kern, Penn Edmonds, Ellen C Perrin, Martin T Stein
An 8-year 8-month-old biological female who self-identifies as a boy, Ricardo is brought by his mother for a well-child check to his new pediatrician. Ricardo and his mother report that he is doing well, but have concerns about the upcoming changes associated with puberty. Ricardo states that he is particularly afraid of developing breasts. His mother asks about obtaining a referral to a specialist who can provide "hormone therapy" to delay puberty.Ricardo was adopted from Costa Rica at the age of 2 as a healthy girl named "Angela...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28132863/immune-endocrine-interactions-in-marsupials-and-monotremes
#19
E Peel, K Belov
Interactions between the immune and endocrine systems are not well studied in marsupials and monotremes. One exception to this is the phenomenon of semelparity, which is well covered in the literature as this is an unusual reproductive strategy amongst mammals and is only observed in some dasyurid and didelphid marsupials. Thymus involution provides a direct link between the endocrine and immune systems and warrants further study in marsupials and monotremes. The thymus is a primary immune tissue which is essential for overall immune function...
January 27, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28101640/labia-minora-hypertrophy-causes-impact-on-women-s-health-and-treatment-options
#20
Caterina Gulia, Andrea Zangari, Vito Briganti, Zhoobin H Bateni, Alessandro Porrello, Roberto Piergentili
INTRODUCTION AND HYPOTHESIS: We provide a review of the literature about the onset and development of hypertrophy of the labia minora, together with some expert opinions on the appropriateness of labiaplasty. METHODS: We searched PubMed and used popular search engines, with a greater emphasis on the physiology and hormone-mediated metabolism of these structures, and less emphasis on their surgical treatment. RESULTS: We describe major embryological, cytological, and biochemical features of this anatomical part and summarize the clinical aspects of its hypertrophy, evaluating types of discomfort reported by women and the medical treatments available...
January 18, 2017: International Urogynecology Journal
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