Sonja Kunz, Xiao Wang, Uta Ferrari, Michael Drey, Marily Theodoropoulou, Katharina Schilbach, Martin Reincke, Margit Heier, Annette Peters, Wolfgang Koenig, Tanja Zeller, Barbara Thorand, Martin Bidlingmaier
OBJECTIVE: Measurements utilizing commercially available sets of reagents for determination of steroid hormone profiles by liquid chromatography-tandem-mass-spectrometry (LC MS/MS) become increasingly important for routine laboratories. However, method specific publications of reference intervals obtained from sufficiently large studies are often missing. METHODS: After validation of performance characteristics, a widely available kit for steroid analysis by LC MS/MS was used to measure concentrations of 15 endogenous steroids (aldosterone, cortisol, cortisone, corticosterone, 11 deoxycortisol, 21 deoxycortisol, dehydroepiandrosterone sulfate, estradiol, testosterone, androstenedione, dihydrotestosterone, dehydroepiandrosterone, 17 hydroxyprogesterone, 11 deoxycorticosterone, progesterone) in more than 500 blood samples from a population based study...
November 1, 2023: Endocrine Connections