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https://www.readbyqxmd.com/read/28528425/neet-adolescents-grown-up-eight-year-longitudinal-follow-up-of-education-employment-and-mental-health-from-adolescence-to-early-adulthood-in-mexico-city
#1
Raúl A Gutiérrez-García, Corina Benjet, Guilherme Borges, Enrique Méndez Ríos, María Elena Medina-Mora
The purpose is to examine the socio-demographic and mental health outcomes in early adulthood of those who as adolescents were not in education, employment or training, termed NEET, compared to their counterparts who studied, worked, or both. One thousand and seventy-one youth residing in Mexico City participated in a representative, prospective, longitudinal 8-year two-Wave cohort study. At Wave I the participants were aged 12-17 and at Wave II aged 19 and 26. The Composite International Diagnostic Interview assessed psychiatric disorders, substance use and abuse, suicidal behavior, interpersonal relationships, employment and education...
May 20, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28527521/association-between-allergies-and-psychiatric-disorders-in-patients-undergoing-invasive-procedures
#2
Dwight Aberle, Stephanie E Wu, Rahmi Oklu, Joseph Erinjeri, Amy R Deipolyi
BACKGROUND: Associations between allergies and psychiatric disorders have been reported in the context of depression and suicide; psychiatric disorders may affect pain perception. OBJECTIVE: To investigate the relationship of allergies with psychiatric disorders and pain perception in the context of invasive procedures, specifically during tunneled hemodialysis catheter placement. METHODS: We identified 89 patients (51 men, 38 women), mean age 66 years (range: 23-96), who underwent tunneled hemodialysis catheter placement (1/2014-2/2015), recording numeric rating scale pain scores, medications, psychiatric history, allergies, and smoking status...
March 28, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28527083/shared-mechanisms-of-epilepsy-migraine-and-affective-disorders
#3
Davide Zarcone, Simona Corbetta
Since the nineteenth century several clinical features have been observed in common between migraine and epilepsy (such as episodic attacks, triggering factors, presence of aura, frequent familiarity), but only in recent years researchers have really engaged in finding a common pathogenic mechanism. From studies of disease incidence, we understand how either migraine among patients with epilepsy or epilepsy among migraine patients are more frequent than in the general population. This association may result from a direct causality, by the same environmental risk factors and/or by a common genetic susceptibility...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526897/the-impact-of-pre-injury-direct-oral-anticoagulants-compared-to-warfarin-in-geriatric-g-60-trauma-patients
#4
J F Barletta, S Hall, J F Sucher, J K Dzandu, M Haley, A J Mangram
PURPOSE: Pre-injury oral anticoagulants are associated with worse outcomes in geriatric (G-60) trauma patients, but there are limited data comparing warfarin with direct oral anticoagulants (DOAC). We sought to compare outcomes in G-60 trauma patients taking pre-injury DOACs vs. warfarin. METHODS: All trauma patients, age ≥60 who were admitted to the hospital and taking an oral anticoagulant pre-injury were retrospectively identified. Patients were excluded if their reason for admission was a suicide attempt or penetrating extremity injury...
May 19, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28526869/blocking-of-carnitine-palmitoyl-transferase-1-potently-reduces-stress-induced-depression-in-rat-highlighting-a-pivotal-role-of-lipid-metabolism
#5
Anne Skøttrup Mørkholt, Ove Wiborg, Jette G K Nieland, Søren Nielsen, John Dirk Nieland
Major depressive disorder is a complex and common mental disease, for which the pathology has not been elucidated. The purpose of this study is to provide knowledge about the importance of mitochondrial dysfunction, dysregulated lipid metabolism and inflammation. Mitochondrial carnitine palmitoyl transferase 1a (CPT1a) is a key molecule involved in lipid metabolism and mutations in CPT1a causing reduced function is hypothesized to have a protective role in the development of depression. Moreover, CPT1a is found to be upregulated in suicide patients with history of depression...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28525964/an-observational-study-of-suicide-death-in-homeless-and-precariously-housed-people-in-toronto
#6
Mark Sinyor, Nicole Kozloff, Catherine Reis, Ayal Schaffer
OBJECTIVE: Homelessness has been identified as an important risk factor for suicide death, but there is limited research characterising homeless people who die by suicide. The goal of this study is to identify personal, clinical, and suicide method-related factors that distinguish homeless and precariously housed people who die from suicide from those who are not homeless at the time of suicide. METHODS: Coroner records were reviewed for all suicide deaths in Toronto from 1998 to 2012...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28525821/effect-of-exercise-augmentation-of-cognitive-behavioural-therapy-for-the-treatment-of-suicidal-ideation-and-depression
#7
Abbas Abdollahi, Daniel M LeBouthillier, Mahmoud Najafi, Gordon J G Asmundson, Simin Hosseinian, Shahriar Shahidi, Per Carlbring, Atefeh Kalhori, Hassan Sadeghi, Marzieh Jalili
BACKGROUND: Suicidal ideation and depression are prevalent and costly conditions that reduce quality of life. This study was designed to determine the efficacy of exercise as an adjunct to cognitive behavioural therapy (CBT) for suicidal ideation and depression among depressed individuals. METHODS: In a randomized clinical trial, 54 mildly to moderately depressed patients (54% female, mean age=48.25) were assigned to a combined CBT and exercise group or to a CBT only group...
May 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28524765/what-can-critical-suicidology-do
#8
Jennifer White
Critical suicidology is an emerging area of scholarship and praxis that brings together academics, community activists, service users, practitioners, policy makers, family members and persons with lived experience, to rethink what it means to study suicide and enact practices of suicide prevention in more diverse and creative, less psycho-centric and less depoliticized, ways. In this paper I begin to articulate what it might mean to "think like a critical suicidologist," the questions that might get asked from this position, the academic and activist allies who might get recruited to the cause, and the potential cracks we might open up in pursuit of a more hopeful, life-affirming, and just future...
May 19, 2017: Death Studies
https://www.readbyqxmd.com/read/28524755/construction-of-suicidal-ideation-in-medical-records
#9
Dariusz Galasiński, Justyna Ziółkowska
In this paper we are interested in exploring discursive transformation of patients' stories
of suicidal ideation into medical discourses. In other words, we focus on how the narrated experience of suicidal thoughts made during the psychiatric assessment interview is recorded in the patients' medical record. Our data come from recordings of psychiatric interviews, as well as the doctors' notes in the medical records made after the interviews, collected in psychiatric hospitals in Poland. Assuming a constructionist view of discourse, we demonstrate that lived experience of suicide ideation resulting in stories of a complex and homogeneous group of "thoughts" is reduced to brief statements of fact of presence/existence...
May 19, 2017: Death Studies
https://www.readbyqxmd.com/read/28522433/beneficial-and-harmful-effects-of-educative-suicide-prevention-websites-randomised-controlled-trial-exploring-papageno-v-werther-effects
#10
Benedikt Till, Ulrich S Tran, Martin Voracek, Thomas Niederkrotenthaler
BackgroundSuicide prevention organisations frequently use websites to educate the public, but evaluations of these websites are lacking.AimsTo examine the effects of educative websites and the moderating effect of participant vulnerability.MethodA total of 161 adults were randomised to either view an educative website on suicide prevention or an unrelated website in a single-blinded randomised controlled trial (trial registration with the American Economic Association's registry: RCT-ID: 000924). The primary outcome was suicidal ideation; secondary outcomes were mood, suicide-prevention-related knowledge and attitudes towards suicide/seeking professional help...
May 18, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28522204/peg-interferon-plus-nucleotide-analogue-treatment-versus-no-treatment-in-patients-with-chronic-hepatitis-b-with-a-low-viral-load-a-randomised-controlled-open-label-trial
#11
Annikki de Niet, Louis Jansen, Femke Stelma, Sophie B Willemse, Sjoerd D Kuiken, Sebastiaan Weijer, Carin M J van Nieuwkerk, Hans L Zaaijer, Richard Molenkamp, R Bart Takkenberg, Maarten Koot, Joanne Verheij, Ulrich Beuers, Hendrik W Reesink
BACKGROUND: Antiviral treatment is currently not recommended for patients with chronic hepatitis B with a low viral load. However, they might benefit from acquiring a functional cure (hepatitis B surface antigen [HBsAg] loss with or without formation of antibodies against hepatitis B surface antigen [anti-HBs]). We assessed HBsAg loss during peg-interferon-alfa-2a (peg-IFN) and nucleotide analogue combination therapy in patients with chronic hepatitis B with a low viral load. METHODS: In this randomised controlled, open-label trial, patients were enrolled from the Academic Medical Center (AMC), Amsterdam, Netherlands...
May 15, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28521846/measures-of-suicidality-in-phase-3-clinical-trials-of-levomilnacipran-er-in-adults-with-major-depressive-disorder
#12
Michael E Thase, Carl Gommoll, Changzheng Chen, Kenneth Kramer, Arif Khan, Suresh Durgam
OBJECTIVE: To evaluate the effects of levomilnacipran extended-release (ER) on suicidal ideation and behavior in adults with major depressive disorder (MDD). METHODS: Post hoc analyses were conducted in patients from 4 randomized, double-blind, placebo-controlled trials and a long-term, open-label extension study of levomilnacipran ER (40-120 mg/d) in adults with MDD. Analyses included incidence of suicide-related treatment-emergent adverse events (TEAEs); incidence of Columbia-Suicide Severity Rating Scale (C-SSRS) suicidal ideation (score=1-5) and behavior (score=6-10); percent of patients who shifted from no C-SSRS suicidal ideation/behavior at baseline to suicidal ideation during treatment (worsened from score=0 to score=1-5), or vice-versa (improved from score=1-5 to score=0)...
May 19, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28521647/a-qualitative-investigation-of-lay-perspectives-of-diagnosis-and-self-management-strategies-employed-by-people-with-progressive-multiple-sclerosis
#13
Julia Frost, Jane Grose, Nicky Britten
This article explores how people with progressive multiple sclerosis give meaning to their experiences. It builds upon the self-management literature, which has captured the tension between the desire for retaining normalcy and the increasing burden of self-management associated with chronic disease progression. This repeat interview study is empirically grounded in 28 interviews with 14 people with progressive multiple sclerosis. We identified gender differences in diagnosis-seeking which impacted subsequent sense-making...
May 2017: Health (London)
https://www.readbyqxmd.com/read/28521147/a-pilot-study-of-differential-brain-activation-to-suicidal-means-and-dna-methylation-of-cacna1c-gene-in-suicidal-attempt-patients
#14
Young Jong Kim, Hae Jeong Park, Geon-Ho Jahng, Sang Min Lee, Won Sub Kang, Su Kang Kim, Tae Kim, Ah Rang Cho, Jin Kyung Park
Suicide is a serious public health problem. In this study, we investigated functional brain changes to novel visual stimuli of suicidal means, DNA methylation status, and the relationship between the two markers. 14 suicidal attempt patients (SAs) and 22 healthy controls were included. Pictures of facial expressions and suicidal means were shown to subjects during fMRI scanning. 11 CpG sites within transcription factor binding site of CACNA1C gene were selected. In knives (K) vs. natural landscape (NL) condition, left middle frontal gyrus (Brodmann's area, BA 6 and 46) and left inferior frontal gyrus (BA 9) were shown to be significantly higher brain activation in the SAs than the controls (p<0...
May 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28521111/the-role-of-gender-in-suicidal-ideation-among-long-term-opioid-users
#15
Kirsten Marchand, Heather Palis, Jill Fikowski, Scott Harrison, Patricia Spittal, Martin T Schechter, Eugenia Oviedo-Joekes
OBJECTIVE: This study aims to examine factors associated with suicidal ideation among people with opioid dependence and to explore whether these factors are gender-specific. METHODS: Cross-sectional data were collected among long-term opioid-dependent individuals ( n = 176; 46.0% women). Lifetime histories of suicidal ideation were measured using the Composite International Diagnostic Interview, and additional data were collected regarding sociodemographic characteristics, drug use, health, and adverse life events...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28520881/sleep-apnea-disability-pension-and-cause-specific-mortality-a-nationwide-register-linkage-study
#16
Naja Hulvej Rod, Linnea Kjeldgård, Torbjörn Åkerstedt, Jane E Ferrie, Paula Salo, Jussi Vahtera, Kristina Alexanderson
Sleep apnea is a common problem affecting daily functioning and health. We evaluated associations between sleep apnea and disability pension and mortality in a prospective study of 74,543 cases of sleep apnea (60,125 outpatient; 14,418 inpatient) from the Swedish Patient Register; 2000-2009 inclusive. Cases were matched to five non-cases (n = 371,592) and followed from diagnosis/inclusion via nationwide registers until Dec 31 2010. During a mean (standard deviation) follow-up of 5.1 (2.7) years, 13% men and 21% women with inpatient sleep apnea were disability pensioned...
May 18, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28520735/pain-in-methadone-patients-time-to-address-undertreatment-and-suicide-risk-anrs-methaville-trial
#17
Sandra Nordmann, Antoine Vilotitch, Caroline Lions, Laurent Michel, Marion Mora, Bruno Spire, Gwenaelle Maradan, Marc-Karim Bendiane, Alain Morel, Perrine Roux, Patrizia Carrieri
BACKGROUND: Pain in opioid-dependent patients is common but data measuring the course of pain (and its correlates) using validated scales in patients initiating methadone treatment are sparse. We aimed to assess pain and its interference in daily life, associated correlates, and undertreatment before and during methadone treatment. METHODS: This is a secondary analysis using longitudinal data of a randomized trial comparing two methadone initiation models. We assessed the effect of methadone initiation and other correlates on pain intensity and interference (using the Brief Pain Inventory) at months 0, 6 and 12 using a mixed multinomial logistic regression model...
2017: PloS One
https://www.readbyqxmd.com/read/28517969/prevalence-and-determinants-of-depression-among-patients-under-the-care-of-traditional-health-practitioners-in-a-kenyan-setting-policy-implications
#18
Christine W Musyimi, Victoria N Mutiso, Abednego M Musau, Lydia K Matoke, David M Ndetei
In Kenya, there is paucity of information on depression among traditional health practitioner (THP) patients, particularly in rural areas. The aim of this study was to estimate prevalence and identify determinants of major depressive disorder (MDD) among patients of THP in rural Kenya using the World Health Organization (WHO) Mental Health Gap Action Programme Intervention Guideline (mhGAP-IG). All adult patients seeking care from trained THPs (either traditional healers such as diviners and herbalists or faith healers, who use treatments such as prayers, laying hands on patients, or providing holy water and ash to their patients) over a period of 3 months (September 2014 to November 2014) were screened for depression using mhGAP-IG and their sociodemographic characteristics recorded...
January 1, 2017: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28516857/co-occurring-cyberbullying-and-school-bullying-victimization-and-associations-with-mental-health-problems-among-canadian-middle-and-high-school-students
#19
Hugues Sampasa-Kanyinga
This study examined the associations between co-occurring cyberbullying and school bullying victimization with poor self-rated mental health, psychological distress, and suicidal ideation and attempts among 4,886 Canadian students in Grades 7-12 and tested whether these associations differed between middle and high school students. There are 12.2% of students who were victims of both cyberbullying and school bullying. After adjusting for covariates, victims of both cyberbullying and school bullying presented the highest odds of poor self-rated mental health (odds ratio [OR] = 5...
May 17, 2017: Violence and Victims
https://www.readbyqxmd.com/read/28516838/acute-alcohol-use-history-of-homelessness-and-intent-of-injury-among-a-sample-of-adult-emergency-department-patients
#20
Katelyn K Jetelina, Jennifer M Reingle Gonzalez, Carlos V R Brown, Michael L Foreman, Craig Field
BACKGROUND: The literature is clear that adults who are currently homeless also have higher rates of intentional injuries, such as assault and suicide attempts. No study has assessed whether intentional injuries are exacerbated because of substance use among adults with a history of homelessness. METHODS: Data were obtained from a cohort of adults admitted to 3 urban emergency departments (EDs) in Texas from 2007 to 2010 (N = 596). Logistic regression analyses were used to determine whether a history of homelessness was associated with alcohol use at time of injury in intentional violent injuries (gunshot, stabbing, or injury consistent with assault)...
May 17, 2017: Violence and Victims
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