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https://www.readbyqxmd.com/read/28521797/multiple-cause-of-death-data-among-people-with-aids-in-italy-a-nationwide-cross-sectional-study
#1
Enrico Grande, Antonella Zucchetto, Barbara Suligoi, Francesco Grippo, Marilena Pappagallo, Saverio Virdone, Laura Camoni, Martina Taborelli, Vincenza Regine, Diego Serraino, Luisa Frova
BACKGROUND: Multiple cause-of-death (MCOD) data allow analyzing the contribution to mortality of conditions reported on the death certificate that are not selected as the underlying cause of death. Using MCOD data, this study aimed to fully describe the cause-specific mortality of people with AIDS (PWA) compared to people without AIDS. METHODS: We conducted a nationwide investigation based on death certificates of 2,515 Italian PWA and 123,224 people without AIDS who had died between 2006 and 2010...
May 18, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28516237/rheumatoid-factor-positivity-increases-all-cause-and-cancer-mortality-a-cohort-study
#2
Joong Kyong Ahn, Jiwon Hwang, Yoosoo Chang, Seungho Ryu
The aim of this study was to determine whether rheumatoid factor (RF) is associated with mortality from all-cause, cardiovascular disease (CVD), and cancer in the healthy adults. We recruited South Korean health check-up examinees without rheumatoid arthritis (RA). A cohort study was performed in 295,837 participants presumably free of osteoarthritis or RA, and who had undergone health screening between 2002 and 2012 and been followed up to determine the risk of all-cause, CVD, and cancer-specific mortality with respect to the presence or titer of RF...
May 17, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28515098/collagen-turnover-markers-in-relation-to-future-cardiovascular-and-noncardiovascular-disease-the-multi-ethnic-study-of-atherosclerosis
#3
Daniel A Duprez, Myron D Gross, Otto A Sanchez, Jorge R Kizer, Joachim H Ix, Joao Lima, Russell P Tracy, David R Jacobs
BACKGROUND: Sustained remodeling of extracellular matrix can compromise organs and tissues. Procollagen type III N-terminal propeptide (PIIINP) and collagen type I carboxy-terminal telopeptide (ICTP) reflect collagen synthesis and degradation. We studied their predictive value for future death and disease. METHODS: A total of 3068 men and women in the Multi-Ethnic Study of Atherosclerosis who were free of cardiovascular disease (CVD) and in generally good health had a baseline blood sample taken for ICTP and PIIINP...
May 17, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28505629/impacts-and-mitigation-of-excess-diesel-related-nox-emissions-in-11-major-vehicle-markets
#4
Susan C Anenberg, Joshua Miller, Ray Minjares, Li Du, Daven K Henze, Forrest Lacey, Christopher S Malley, Lisa Emberson, Vicente Franco, Zbigniew Klimont, Chris Heyes
Vehicle emissions contribute to fine particulate matter (PM2.5) and tropospheric ozone air pollution, affecting human health, crop yields and climate worldwide. On-road diesel vehicles produce approximately 20 per cent of global anthropogenic emissions of nitrogen oxides (NOx), which are key PM2.5 and ozone precursors. Regulated NOx emission limits in leading markets have been progressively tightened, but current diesel vehicles emit far more NOx under real-world operating conditions than during laboratory certification testing...
May 15, 2017: Nature
https://www.readbyqxmd.com/read/28505261/survival-and-causes-of-death-among-people-with-clinically-diagnosed-synucleinopathies-with-parkinsonism-a-population-based-study
#5
Rodolfo Savica, Brandon R Grossardt, James H Bower, J Eric Ahlskog, Bradley F Boeve, Jonathan Graff-Radford, Walter A Rocca, Michelle M Mielke
Importance: To our knowledge, a comprehensive study of the survival and causes of death of persons with synucleinopathies compared with the general population has not been conducted. Understanding the long-term outcomes of these conditions may inform patients and caregivers of the expected disease duration and may help with care planning. Objective: To compare survival rates and causes of death among patients with incident, clinically diagnosed synucleinopathies and age- and sex-matched referent participants...
May 15, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28501755/new-challenges-for-verbal-autopsy-considering-the-ethical-and-social-implications-of-verbal-autopsy-methods-in-routine-health-information-systems
#6
REVIEW
Hebe N Gouda, Abraham D Flaxman, Claire E Brolan, Rohina Joshi, Ian D Riley, Carla AbouZahr, Sonja Firth, Rasika Rampatige, Alan D Lopez
Verbal autopsy (VA) methods are designed to collect cause-of-death information from populations where many deaths occur outside of health facilities and where death certification is weak or absent. A VA consists of an interview with a relative or carer of a recently deceased individual in order to gather information on the signs and symptoms the decedent presented with prior to death. These details are then used to determine and assign a likely cause-of-death. At a population level this information can be invaluable to help guide prioritisation and direct health policy and services...
May 3, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28500217/glucose-peaks-and-the-risk-of-dementia-and-20-year-cognitive-decline
#7
Andreea M Rawlings, A Richey Sharrett, Thomas H Mosley, Shoshana H Ballew, Jennifer A Deal, Elizabeth Selvin
OBJECTIVE: Hemoglobin A1c (HbA1c), a measure of average blood glucose level, is associated with the risk of dementia and cognitive impairment. However, the role of glycemic variability or glucose excursions in this association is unclear. We examined the association of glucose peaks in midlife, as determined by the measurement of 1,5-anhydroglucitol (1,5-AG) level, with the risk of dementia and 20-year cognitive decline. RESEARCH DESIGN AND METHODS: Nearly 13,000 participants from the Atherosclerosis Risk in Communities (ARIC) study were examined...
May 12, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28499667/insight-into-the-incidence-of-acute-aortic-dissection-in-the-german-region-of-berlin-and-brandenburg
#8
S D Kurz, V Falk, J Kempfert, M Gieb, T M Ruschinski, M Kukucka, M Tsokos, H Grubitzsch, H Herbst, J Semmler, C Buschmann
BACKGROUND: Stanford acute type A aortic dissection (ATAAD) is a potentially lethal condition. Epidemiology studies show a statistical incidence in Europe of approximately 2-16 cases/100,000 inhabitants/year. In Germany, the estimated incidence (here subsumed under "thoracic aortic dissection" with 4.63 cases/100,000 inhabitants/year) is mainly extracted from medical death certificates by the German Federal Statistical Office. The prehospital incidence of ATAAD deaths is largely unknown...
May 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28497238/obesity-related-mortality-in-france-italy-and-the-united-states-a-comparison-using-multiple-cause-of-death-analysis
#9
Magali Barbieri, Aline Désesquelles, Viviana Egidi, Elena Demuru, Luisa Frova, France Meslé, Marilena Pappagallo
OBJECTIVES: We investigate the reporting of obesity on death certificates in three countries (France, Italy, and the United States) with different levels of prevalence, and we examine which causes are frequently associated with obesity. METHODS: We use cause-of-death data for all deaths at ages 50-89 in 2010-2011. Since obesity may not be the underlying cause (UC) of death, we compute age- and sex-standardized death rates considering all mentions of obesity (multiple causes or MC)...
May 11, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28494634/changing-place-of-death-in-children-who-died-after-discharge-from-paediatric-intensive-care-units-a-national-data-linkage-study
#10
Lorna K Fraser, Sarah Fleming, Roger Parslow
BACKGROUND: Although child mortality is decreasing, more than half of all deaths in childhood occur in children with a life-limiting condition whose death may be expected. AIM: To assess trends in place of death and identify characteristics of children who died in the community after discharge from paediatric intensive care unit. DESIGN: National data linkage study. SETTING/PARTICIPANTS: All children resident in England and Wales when admitted to a paediatric intensive care unit in the United Kingdom (1 January 2004 and 31 December 2014) were identified in the Paediatric Intensive Care Audit Network dataset...
May 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28492780/-epidemiological-profile-of-traffic-accidents-in-mar%C3%A3-lia-s%C3%A3-o-paulo-state-brazil-2012
#11
Carina Rejane Fernandes Biffe, Airi Harada, Alexander Bocchi Bacco, Carine Silveira Coelho, João Lucas Ferrareto Baccarelli, Karoline Lopes Silva, Luzmarina Aparecida Doretto Braccialli, Margarete Beloni, Maria Luiza Guidinho Bernardes, Stephanie Ribeiro Lacerda, Thainá Inoue Silva
OBJECTIVE: to describe the profile of victims of traffic accidents and traffic-related deaths in Marília-SP, Brazil. METHODS: this is a descriptive study, based on data from police reports (PR) and Death Certificates (DC), in 2012. RESULTS: 1,537 PR were gathered; among the 3,257 individuals involved in traffic accidents, 67.3% were men, and 53.3% were between 20-39 years of age; most accidents occurred on road intersections (35.2%), at 8 a...
April 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28483570/contribution-of-maternal-age-and-pregnancy-checkbox-on-maternal-mortality-ratios-in-the-united-states-1978-2012
#12
Nicole L Davis, Donna L Hoyert, David A Goodman, Ashley H Hirai, William M Callaghan
BACKGROUND: Maternal mortality ratios (MMR) appear to have increased in the United States over the last decade. Three potential contributing factors are: 1) a shifting maternal age distribution, 2) changes in age-specific MMR, and 3) the addition of a checkbox indicating recent pregnancy on the death certificate. OBJECTIVE: Determine the contribution of rising maternal age on changes in MMR from 1978-2012, and estimate the contribution of the pregnancy checkbox on increases in MMR over the last decade...
May 5, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28479411/end-of-life-place-of-care-health-care-settings-and-health-care-transitions-among-cancer-patients-impact-of-an-integrated-cancer-palliative-care-plan
#13
V Casotto, M Rolfini, E Ferroni, V Savioli, N Gennaro, F Avossa, M Cancian, F Figoli, D Mantoan, A Brambilla, M C Ghiotto, U Fedeli, M Saugo
CONTEXT: Frequent end-of-life health care setting transitions can lead to an increased risk of fragmented care and exposure to unnecessary treatments. OBJECTIVES: We assessed the relationship between the presence and the intensity of an Integrated Cancer Palliative Care plan and the occurrence of multiple transitions during the last month of life. METHODS: Decedents of cancer aged 18-85 years residents in two Regions of Italy where investigated accessing their integrated administrative data (Death Certificates, Hospital Discharges, Hospice and Home care records)...
May 4, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28479274/validity-of-total-kihon-checklist-score-for-predicting-the-incidence-of-3-year-dependency-and-mortality-in-a-community-dwelling-older-population
#14
Shosuke Satake, Hiroshi Shimokata, Kazuyoshi Senda, Izumi Kondo, Kenji Toba
OBJECTIVES: To validate the ability of the total Kihon checklist (t-KCL) score to predict the incidence of dependency or death within 3 years in a community-dwelling older population. DESIGN: Population-based longitudinal observational study. SETTING: Town of Higashi-ura, Japan. PARTICIPANTS: A total of 5542 independent seniors who were residents in the town of Higashi-ura. MEASUREMENTS: The KCL questionnaire was sent to independent older residents...
May 4, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28465455/coronary-artery-calcium-and-risk-of-dementia-in-mesa-multi-ethnic-study-of-atherosclerosis
#15
Akira Fujiyoshi, David R Jacobs, Annette L Fitzpatrick, Alvaro Alonso, Daniel A Duprez, A Richey Sharrett, Teresa Seeman, Michael J Blaha, José A Luchsinger, Stephen R Rapp
BACKGROUND: Studies suggest a link between vascular injuries and dementia. Only a few studies, however, examined a longitudinal relation of subclinical vascular disease with dementia. We tested whether baseline coronary artery calcium (CAC), a biomarker of subclinical vascular disease, is associated with incident dementia independent of vascular risk factors and APOE-ε4 genotype in a community-based sample. METHODS AND RESULTS: We analyzed 6293 participants of MESA (Multi-Ethnic Study of Atherosclerosis), aged 45 to 84 years at baseline (2000-2002), initially free of cardiovascular disease and noticeable cognitive deficit...
May 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28456800/inhaled-glucocorticoids-and-pneumonia-in-preterm-infants-post-hoc-results-from-the-neurosis-trial
#16
Alexander Koch, Karen Kreutzer, Gabriele von Oldershausen, Christian F Poets, Dirk Bassler
BACKGROUND: Inhaled glucocorticoids may increase the risk of pneumonia in adults. Thus, respiratory infections may be a potential explanation for the non-significantly increased mortality seen in the glucocorticoid group in the largest randomized trial on inhaled glucocorticoids for preventing bronchopulmonary dysplasia in preterm infants published to date (NEuroSIS). OBJECTIVE: To evaluate the effect of inhaled budesonide on the risk of death due to respiratory infections in the NEuroSIS trial...
April 29, 2017: Neonatology
https://www.readbyqxmd.com/read/28456095/a-survey-of-medical-examiner-death-certification-of-vignettes-on-death-in-epilepsy-gaps-in-identifying-sudep
#17
Daniel S Atherton, Gregory G Davis, Cyndi Wright, Orrin Devinsky, Dale Hesdorffer
OBJECTIVE: Lack of standardized terminology on death certificates (DCs) of SUDEP type cases may obscure the presence of epilepsy in these deaths. Most DCs for individuals dying unexpectedly with epilepsy are certified by medical examiners (MEs). The purpose of this study was to gauge death certification practices of MEs when interpreting SUDEP cases and assess implications for valid surveillance of SUDEP. MATERIALS AND METHODS: A survey consisting of clinical vignettes describing deaths in individuals with epilepsy was sent to medical examiners...
April 22, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28453098/-causes-of-death-from-breast-cancer-in-colombia
#18
Mario A González-Mariño
Objective To review the direct causes of death from breast cancer in Colombia according to data from death certificates in 2008. Material and Methods We reviewed the direct causes of death in patients whose code of underlying cause of death was malignant tumor of the breast according to the National Statistics Department of Colombia's (DANE from Spanish initials) records of death in 2008. Distribution is evaluated by diagnostic code, age, educational level, marital status, social security and place of death...
June 2016: Revista de Salud Pública
https://www.readbyqxmd.com/read/28448893/diabetes-status-modifies-the-association-between-carotid-intima-media-thickness-and-incident-heart-failure-the-atherosclerosis-risk-in-communities-study
#19
Valery S Effoe, Eric E McClendon, Carlos J Rodriguez, Lynne E Wagenknecht, Gregory W Evans, Patricia P Chang, Alain G Bertoni
AIMS: Increasing carotid intima-media thickness (CIMT) is associated with incident heart failure (HF). We investigated whether this association differs by diabetes status. METHODS: We characterized 13,590 Atherosclerosis Risk in Communities Study participants free of baseline HF into normal fasting glucose (NFG, glucose <100mg/dl), impaired fasting glucose (IFG, glucose 100-125mg/dl), and type 2 diabetes (T2D, glucose ≥126mg/dl, self-report, or use of diabetes drugs)...
April 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28442284/fitness-fatness-index-and-alzheimer-specific-mortality
#20
Emily Frith, Paul D Loprinzi
OBJECTIVE: We evaluated the specific association between a Fitness Fat Index (FFI) and Alzheimer's-specific mortality among a national sample of the broader U.S. adult population. METHODS: FFI was calculated as cardiorespiratory fitness (CRF) divided by waist-to-height ratio (WHR). Data from the 1999-2006 National Health and Nutrition Examination Survey (NHANES) were used to identify 16,146 participants, ages 20-85. Data from participants in these cycles were linked to death certificate data from the National Death Index...
April 22, 2017: European Journal of Internal Medicine
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