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Mina Cheraghi Nirumand, Marziyeh Hajialyani, Roja Rahimi, Mohammad Hosein Farzaei, Stéphane Zingue, Seyed Mohammad Nabavi, Anupam Bishayee
Kidney stones are one of the oldest known and common diseases in the urinary tract system. Various human studies have suggested that diets with a higher intake of vegetables and fruits play a role in the prevention of kidney stones. In this review, we have provided an overview of these dietary plants, their main chemical constituents, and their possible mechanisms of action. Camellia sinensis (green tea), Rubus idaeus (raspberry), Rubia cordifolia (common madder), Petroselinum crispum (parsley), Punica granatum (pomegranate), Pistacia lentiscus (mastic), Solanum xanthocarpum (yellow-fruit nightshade), Urtica dioica (stinging nettle), Dolichos biflorus ( horse gram ), Ammi visnaga (khella), Nigella sativa (black-cumin), Hibiscus sabdariffa (roselle), and Origanum vulgare (oregano) have received considerable interest based on scientific evidence...
March 7, 2018: International Journal of Molecular Sciences
Aslı Turan, Sibel Soycan Önenç
Objective: This study was carried out to determine the effects of cumin essential oil on the silage fermentation, aerobic stability and in vitro digestibility of alfalfa silages. Methods: Alfalfa was harvested at early bloom (5 th cutting) stage in October and wilted for about 3 hours. The research was carried out at three groups which were the control group where no additive control was done (CON), cumin essential oil (CMN3) with 300 mg/kg and CMN5 with 500 mg/kg cumin essential oil addition...
March 2, 2018: Asian-Australasian Journal of Animal Sciences
Atefeh Bahmanzadegan, Vahid Rowshan, Faraneh Zareiyan, Ahmad Hatami
Lagoecia cuminoides L. belongs to the family of Umbelliferae (Apiaceae), and known also as common wild cumin. The aerial parts of L. cuminoides were collected at the flowering stage and dried, then the methanolic extract was analyzed for polyphenol compounds identified by HPLC-DAD and antioxidant activity (DPPH(2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay). It was found that the predominant phenolic constituents were chlorogenic acid, hesperidin, rosmarinic acid, hesperetin and vanillin. The antioxidant activity of methanolic extract from L...
March 7, 2018: Natural Product Research
Jennica M Young, Michael R Hoane
After sustaining a traumatic brain injury (TBI), a person's ability to make daily decisions can be affected. Simple tasks such as, deciding what to wear are no longer effortless choices, but are instead difficult decisions. This study explored the use of a discrimination task with a magnesium treatment in order to examine how decision-making skills are affected after TBI and if the treatment helped to attenuate cognitive and motor impairments. Thirty-one male rats were separated into MAG/TBI, VEH/TBI, or VEH/Sham groups...
March 1, 2018: Brain Research Bulletin
Bouchra Sayed Ahmad, Thierry Talou, Evita Straumite, Martins Sabovics, Zanda Kruma, Zeinab Saad, Akram Hijazi, Othmane Merah
Malnutrition continues to be a key health problem in developing regions. The valorization of food waste appears as an ideal way to prevent malnutrition and improve people's access to food. Cumin ( Cuminum cyminum L.) and caraway ( Carum carvi L.) oilseeds are commonly used for cuisine and medicinal purposes. However, remaining cakes after oil extraction are usually underutilized. In order to assess the usefulness of these by-products in food applications, this study investigated the effect of their addition to protein bread formulations...
February 25, 2018: Foods (Basel, Switzerland)
P Kumar, A K Patra, G P Mandal, B C Debnath
A study was conducted to investigate the dietary supplementation of black cumin seeds (BCS) on carcass characteristics, chemical and fatty acid (FA) composition and antioxidant properties of thigh and breast meat of broiler chickens at 42 days of age. Three hundred sixty 1-day-old broiler chickens were allocated to five dietary treatment groups (each group containing eight replicate pens with each pen containing nine broiler chickens): basal diet (control; CON), CON + 0.05 g/kg of bacitracin methylene disalicylate (AB), CON + 5 g/kg of BCS (low dose of BCS), CON + 10 g/kg of BCS (medium dose of BCS) and CON + 20 g/kg of BCS (high dose of BCS)...
February 28, 2018: Journal of Animal Physiology and Animal Nutrition
Tarek A Morsy, Ahmed E Kholif, Osama H Matloup, Amgad Abu Elella, Uchenna Y Anele, Joel S Caton
The experiments reported in this Research Paper aimed to study the effects of mustard and cumin seeds inclusion on feed utilisation, milk production, composition, and profile of milk fatty acids in lactating Damascus goats. The study was a completely randomised design with repeated measurements in time using fifteen goats (6 ± 2 d of lactation) divided into 3 treatments (5 goats per treatment). Goats were offered a control diet of berseem clover and concentrates (1 : 1 dry matter (DM) basis) or the control diet supplemented with either 10 g/d of dried mustard seeds (mustard treatment) or 10 g/d of cumin seeds (cumin treatment) for 12 weeks...
February 26, 2018: Journal of Dairy Research
Babar Ali, Mohammad Ali, Saima Amin, Showkat R Mir
The seeds of Nigella sativa Linn. (Ranunculaceae), commonly known as Black cumin, are predominantly used as carminative, antispasmodic, and stimulant. The main objective of the present study was to evaluate the effect of N. sativa seed extract on the permeation of co-infused amoxicillin across the gut wall. The methanolic extract of N. sativa improved intestinal permeability of amoxicillin in in-vitro experiments in a dose-dependent manner. Two new glycosides, decanyl nigelloic acid diglucoside [n-decanyl-3-aldehydic-4-methoxy-5-hydroxy benzoate-5-β-D-glucofuranosyl (2→1)-β-D-glucopyranosyl-(2→1)-β-D-glucopyranoside]] and nigelabdienoyl triglucoside [homo-labd-5, 9(11)-dien-16-onyl-β-D-glucopyranosyl (2→1)-β-D-glucopyranosyl (2→1)-β-D-glucopyranoside], along with seven known fatty acid glycerides/esters, were isolated from the gut permeation enhancing extract...
February 2018: Chinese Journal of Natural Medicines
Roghayeh Karimirad, Mahdi Behnamian, Sara Dezhsetan
The aim of present study was to design a controlled release system using Cuminum cyminum essential oil loaded chitosan nanoparticles (CEO-CSNPs) and evaluate its effect on catalase (CAT), glutathione reductase (GR), peroxidase (POD) activity and ascorbic acid content of Agaricus bisporus fruit bodies during 20 days of storage at 4 °C. The success of encapsulation was evaluated through TEM, DLS, FT-IR and spectrophotometry and its release behavior was studied in buffer solutions with different pH. The CEO-CSNPs exhibited an average size of 30 to 80 nm with a spherical shape...
February 14, 2018: International Journal of Biological Macromolecules
Irum Basheer, Irfan Zia Qureshi
BACKGROUND: Nigella sativa, or commonly called black cumin is a small herb of family Ranunculaceae is a well-known medicinal plant but its effects on tissue mineral concentrations of animal bodies is unknown. PURPOSE: To study the effect of oral administration of fixed oil of black cumin seeds on tissues mineral content using laboratory rats as experimental model. STUDY DESIGN: Experimental animals were exposed to two oral doses of seed oil (60 and 120 ml kg -1 body weight)...
January 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Adam C Cunningham, Sue Delport, Wendy Cumines, Monica Busse, David E J Linden, Jeremy Hall, Michael J Owen, Marianne B M van den Bree
BACKGROUND: 22q11.2 deletion syndrome (22q11.2DS) is associated with high rates of neurodevelopmental disorder, however, the links between developmental coordination disorder (DCD), intellectual function and psychiatric disorder remain unexplored. Aims To establish the prevalence of indicative DCD in children with 22q11.2DS and examine associations with IQ, neurocognition and psychopathology. METHOD: Neurocognitive assessments and psychiatric interviews of 70 children with 22q11...
January 2018: British Journal of Psychiatry: the Journal of Mental Science
Rahele Kargozar, Hoda Azizi, Roshanak Salari
Background: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. Objective: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms...
November 2017: Electronic Physician
Hamid Bakhshabadi, HabibOllah Mirzaei, Alireza Ghodsvali, Seid Mahdi Jafari, Aman Mohammad Ziaiifar
Application of novel technologies such as microwave and pulsed electric fields (PEF) might increase the speed and efficiency of oil extraction. In the present research, PEF (3.25 kV/cm electric field intensity and 30 pulse number) and microwave (540 W for 180 s) pretreatments were used to study the process of oil extraction from black cumin (Nigella sativa) seeds. After applying the selected pretreatments, the oil of seeds was extracted with the use of a screw press and the extraction efficiency, refractive index, oil density, color index, oxidative stability, and chemical components of oil and protein of meal were evaluated...
January 2018: Food Science & Nutrition
Ahmed Abd-Rabou, Amr E Edris
BACKGROUND: Essential oils (EOs) are natural volatile plant extract that have different biological activities including antiproliferative potentials. OBJECTIVE: the current study aims at evaluating the antiproliferative activities of six EOs in their neat state compared to their nanoparticulate form after fabrication in microemulsion against some cancer cell lines. The EOs included marjoram (Origanum majorana), turmeric (Curcuma longa), sweet basil (Ocimum basillicum), clove buds (Syzygium aromaticum), geranium (plargonium graviolenis), and black cumin (Nigella sativa)...
January 10, 2018: Current Clinical Pharmacology
Sophie E Inman, Kate Groves, Bryan McCullough, Milena Quaglia, Chris Hopley
The need for an analytical procedure for the identification of allergens present at trace levels in foods was highlighted by conflicting results in a case of contamination of the spice cumin. The application of a bottom-up proteomics experiment was investigated to identify marker peptides for potential contaminant nuts which could then be monitored with high specificity and sensitivity by selective reaction monitoring experiments. The method developed allowed for the distinction between two closely related Prunus species, almond and mahaleb, in two different spices, cumin and paprika...
April 15, 2018: Food Chemistry
Najla Trabelsi, Stefania M Marotta, Filippo Giarratana, Amani Taamali, Mokhtar Zarrouk, Graziella Ziino, Alessandro Giuffrida
BACKGROUND: Natural compounds are more frequently used against Anisakis, responsible of an important fish borne disease, anisakidosis. The aim of the study was to evaluate the effectiveness of enriched Tunisian olive oil with different spices (Cumin, Turmeric, Clove, Thyme and Lemon) against Anisakis larvae Type 1. RESULTS: In vitro experiment: larvae were submerged separately in the above mentioned oils, and then, examined, to check viability. For each oil, LT50 and LT100 were calculated...
December 28, 2017: Journal of the Science of Food and Agriculture
Moslem Bahmankar, Seyed Mohammad Mahdi Mortazavian, Masoud Tohidfar, Seyed Ahmad Sadat Noori, Ali Izadi Darbandi, Giandomenico Corrado, Rosa Rao
This is the first report evaluating the relationship between the chemical compositions of cumin seeds (based on the analysis of the content of catalase, ascorbate peroxidase, proline, protein, terpenic compounds, alcohol/phenols, aldehydes, and epoxides) and the induction efficiency of somatic embryogenesis in two Iranian superior cumin landraces (Golestan and North Khorasan). Cotyledons isolated from Golestan landrace seeds cultivated on MS medium supplemented with 0.1 mg/L kinetin proved to be the best primary explant for the induction of somatic embryogenesis as well as the regeneration of the whole plantlet...
2017: BioMed Research International
Zeba Farooqui, Faaiza Shahid, Aijaz Ahmed Khan, Farah Khan
Cisplatin (CP) is an effective anti-cancer drug which causes remarkable toxicity to the kidney, particularly to proximal tubules, by generating reactive oxygen species. Nigella sativa (NS), commonly known as "black cumin" reduces the progression of various kidney disorders. Thymoquinone (TQ), the major bioactive constituent of NS seeds, has been credited for various pharmacological effects of NS. Since, a typical clinical CP dosing regimen involves CP administration in multiple cycles over a long time duration, hence the present study aimed to evaluate the renoprotective efficacy of NS oil and TQ against multiple dose CP treatment induced deleterious biochemical and histological alterations in rat kidney...
December 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Arnab Goon, Zareen Khan, Dasharath Oulkar, Raviraj Shinde, Suresh Gaikwad, Kaushik Banerjee
A novel screening and quantitation method is reported for non-target multiresidue analysis of pesticides using ultra-HPLC-quadrupole-Orbitrap mass spectrometry in spice matrices, including black pepper, cardamom, chili, coriander, cumin, and turmeric. The method involved sequential full-scan (resolution = 70,000), and variable data independent acquisition (vDIA) with nine consecutive fragmentation events (resolution = 17,500). Samples were extracted by the QuEChERS method. The introduction of an SPE-based clean-up step through hydrophilic-lipophilic-balance (HLB) cartridges proved advantageous in minimizing the false negatives...
January 12, 2018: Journal of Chromatography. A
Michael J Walker, Malcolm Burns, Milena Quaglia, Gavin Nixon, Christopher J Hopley, Kirstin M Gray, Victoria Moore, Malvinder Singh, Simon Cowen
It is now well known that an incident investigated in the United Kingdom in 2015 of cumin alleged to be contaminated with almond, a risk for people with almond allergy, was caused by the Prunus species, Prunus mahaleb. In the United Kingdom, the Government Chemist offers a route of technical appeal from official findings in the food control system. Findings of almond in two official samples, cumin and paprika, which had prompted action to exclude the consignments from the food chain, were so referred. Herein are described the approaches deployed to resolve the analytical issues during the investigation of the incidents...
January 1, 2018: Journal of AOAC International
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