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https://www.readbyqxmd.com/read/27918224/ocular-autoimmune-systemic-inflammatory-infectious-study-oasis-report-1-epidemiology-and-classification
#1
Elizabeth J Chen, Muhammad Amir Bin Ismail, Helen Mi, Su Ling Ho, Wee Kiak Lim, Stephen C Teoh, Rupesh Agrawal
PURPOSE: To report the epidemiology and classification of ocular inflammation at a tertiary eye care center in Singapore. METHODS: Retrospective cohort study of the clinical records of consecutive new cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database from 2004-2015. RESULTS: A total of 2200 patients were studied from the OASIS database. The most common anatomic diagnosis was anterior uveitis (55.9%), posterior uveitis (17...
December 5, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27861307/epibulbar-plasmacytoma-masquerading-as-subconjunctival-hemorrhage-in-a-patient-with-multiple-myeloma
#2
Amanda Bradley, Amy Estes, Lane Ulrich, Dilip Thomas, David Gay
PURPOSE: We report a 75-year-old woman with a history of multiple myeloma immunoglobulin D (IgD) variant, who presented with an epibulbar plasmacytoma masquerading as a subconjunctival hemorrhage. METHODS: Magnetic resonance imaging of the brain and orbits with and without contrast was obtained and surgical biopsy of the subconjunctival lesion was performed; histopathology confirmed the diagnosis of plasmacytoma. RESULTS: Subconjunctival biopsy revealed a plasma cell neoplasm infiltrate in the episcleral layer...
November 16, 2016: Cornea
https://www.readbyqxmd.com/read/27803867/prevalence-and-characteristics-of-ophthalmological-extra-intestinal-manifestations-in-chinese-patients-with-inflammatory-bowel-disease
#3
Ying-Chao Li, Wei-Zhi Li, Chang-Rui Wu, Yun Feng, Li Ren, Chen Mi, Yang Li
AIM: To investigate the prevalence of ophthalmological extra-intestinal manifestations (O-EIMs) in Chinese patients with inflammatory bowel disease (IBD) and to identify risk factors for the development of O-EIMs. METHODS: The study population consisted of Chinese patients with a definite diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) in a large teaching hospital between January 1995 and December 2014. Demographic and clinical characteristics of patients were extracted retrospectively...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27790380/aqueous-humor-outflow-structure-and-function-imaging-at-the-bench-and-bedside-a-review
#4
Alex S Huang, Chirayu Mohindroo, Robert N Weinreb
Anterior segment glaucoma clinical care and research has recently gained new focus because of novel imaging modalities and the advent of angle-based surgical treatments. Traditional investigation drawn to the trabecular meshwork now emphasizes the entire conventional aqueous humor outflow (AHO) pathway from the anterior chamber to the episcleral vein. AHO investigation can be divided into structural and functional assessments using different methods. The historical basis for studying the anterior segment of the eye and AHO in glaucoma is discussed...
August 2016: Journal of Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27761704/limbal-conjunctival-versus-amniotic-membrane-in-the-intraoperative-application-of-mitomycin-c-for-recurrent-pterygium-a-randomized-controlled-trial
#5
Rongxin Chen, Guofu Huang, Shu Liu, Wenfang Ma, Xiaofang Yin, Shiyou Zhou
PURPOSE: This study compared the outcomes of a limbal conjunctival autograft (LCAG) with those of an amniotic membrane graft (AMG) followed by intraoperative 0.02 % mitomycin C (MMC) to treat recurrent pterygium. METHODS: In this randomized controlled trial, ninety-six eyes with recurrent pterygium were enrolled and randomly allocated into two groups using a computer-generated random number table. Pterygium removal was followed by intraoperative 0.02 % MMC for 3 min and then either LCAG or AMG transplantation...
October 20, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27749794/can-peripheral-optical-coherence-tomography-b-scans-influence-the-surgeon-s-decision-on-episcleral-surgery
#6
Micol Alkabes, Domenico Massaro, Stefano Ranno, Paolo Nucci
PURPOSE: To describe the case of a young boy affected by a rhegmatogenous retinal redetachment in whom the use of peripheral optical coherence tomography led the vitreoretinal surgeon to treat the patient with an additional surgery instead of a "watchful waiting" strategy. METHODS: A 13-year-old boy was referred to the Vitreoretinal Department of the study institution affected by a macula-off rhegmatogenous retinal redetachment in his right eye secondary to a second blunt trauma...
October 3, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27746064/melanomalytic-glaucoma-secondary-to-iris-melanoma
#7
S Ajamil Rodanés, C García-Álvarez, M A Saornil Alvarez, F López-Lara, J M Frutos Baraja, M Quiñones
CLINICAL CASE: A 35-year-old male with unilateral ocular hypertension in the right eye (RE). Anterior segment examination of the RE showed a melanotic lesion. Intraocular pressure (IOP) was 40mmHg in RE. Gonioscopy revealed extension into the anterior chamber angle. Excisional biopsy was performed and consistent with iris melanoma and secondary melanomalytic glaucoma. Brachytherapy was performed as adjuvant therapy. DISCUSSION: In patients presenting with unilateral glaucoma and increased pigmentation in the trabecular meshwork, it is crucial to perform imaging studies...
October 13, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27726522/the-spectrum-of-uveitis-in-southern-vietnam
#8
Myhanh Nguyen, Jay Siak, Soon-Phaik Chee, Vo Quang Hong Diem
PURPOSE: To describe the pattern of uveitis among Vietnamese at two eye hospitals in Southern Vietnam. METHODS: We retrospectively reviewed the charts of 212 consecutive uveitis cases that presented to two eye hospitals in Ho Chi Minh City, Vietnam, from July 2011 to February 2015. The patients were identified from a database maintained by the hospitals. Patients with keratitis, episcleritis, orbital inflammation, post-surgical endophthalmitis, traumatic iritis, and corneal graft rejection were excluded...
October 11, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27717742/effect-of-intraocular-pressure-iop-and-choroidal-circulation-on-controlled-episcleral-drug-delivery-to-retina-vitreous
#9
Jie Li, Bifei Lan, Xiaoli Li, Shumao Sun, Ping Lu, Lingyun Cheng
Transscleral drug delivery may become a safe alternative to the intravitreal injection for chronic retinal diseases such as age-related macular degeneration or diabetic macular edema. However, the drug delivered onto the sclera subjects to vigorous clearance by episcleral and choroidal circulation; in addition, the penetration from episclera to retina needs to overcome counter-directional ocular fluid current driven by intraocular pressure (IOP) as well as unfavorable drug disposition exerted by drug transporters before the drug reach retina...
October 4, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27674991/prior-non-irradiative-focal-therapies-do-not-compromise-the-efficacy-of-delayed-episcleral-plaque-brachytherapy-epbrt-in-retinoblastoma
#10
J T Lucas, B Sharma, C A Billups, I Qaddoumi, T E Merchant, R C Brennan, M W Wilson
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674570/episcleral-brachytherapy-for-ocular-hemangioma-indications-and-outcomes
#11
C A Berriochoa, J H Suh, D A Wilkinson, A Singh
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674435/single-institutional-early-outcomes-of-uveal-melanoma-treated-with-eye-physics-iodine-125-episcleral-plaque-therapy-using-modern-biopsy-techniques-and-intra-operative-ultrasound-guidance
#12
A W J Tann, B S Teh, G D Lewis, S B Scarboro, M E Bretana, P C Croft, E B Butler, P Chevez-Barrios, A C Schefler
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27624855/canine-ocular-onchocerciasis-a-retrospective-review-of-the-diagnosis-treatment-and-outcome-of-16-cases-in-new-mexico-2011-2015
#13
Nancy Johnstone McLean, Kimberly Newkirk, Coenraad M Adema
OBJECTIVE: To describe the clinical exam findings, treatment and outcomes of 16 dogs diagnosed with ocular onchocerciasis in New Mexico. MATERIALS AND METHODS: Records of dogs diagnosed by the primary author were reviewed (2011-2015). Records that were accessible and included a diagnosis of Onchocerca lupi by histopathologic or molecular identification of the nematode were included. RESULTS: Sixteen cases were included. 3/16 dogs were treated with year-round heartworm prophylaxis prior to infection...
September 13, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27574179/episcleral-brachytherapy-of-uveal-melanoma-role-of-intraoperative-echographic-confirmation
#14
Hassan A Aziz, Yahya A Al Zahrani, James Bena, Brandy Lorek, Allan Wilkinson, John Suh, Arun D Singh
PURPOSE: To compare the rates of tumour recurrence following episcleral brachytherapy for uveal melanoma before and after implementation of intraoperative echographic confirmation of plaque placement. MATERIALS AND METHODS: All patients with primary single ciliary body or choroidal melanoma treated with iodine-125 or ruthenium-106 plaque brachytherapy between 1 January 2004 and 30 December 2013 were included. Exclusion criteria were patients with previous radiation treatment and patients who received adjuvant transpupillary thermotherapy...
August 29, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27550224/-diagnosis-and-treatment-of-episcleritis-and-scleritis
#15
C Tappeiner, K Walscheid, A Heiligenhaus
Episcleritis is a benign and self-limiting disease, often with a recurrent course, manifesting mainly in young adults. In less than a third of patients, an associated systemic disease can be found. In contrast, scleritis is observed mainly in patients between the 4th and 6th decade of life, may lead to severe ocular complications, and is often associated with a systemic rheumatological disease. Diffuse, nodular, and necrotizing forms of scleritis can be differentiated. Necrotizing and posterior scleritis have a higher risk of complications and worse visual outcome...
September 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27537266/in-vivo-identification-of-the-posttrabecular-aqueous-outflow-pathway-using-swept-source-optical-coherence-tomography
#16
Akihito Uji, Yuki Muraoka, Nagahisa Yoshimura
PURPOSE: The purpose of this study was to investigate a novel imaging technique to identify the continuous posttrabecular aqueous outflow pathway from a single B-scan, using swept-source optical coherence tomography (SS-OCT). METHODS: Three-dimensional volume scans of the temporal or nasal side of the anterior segment area at the limbus were acquired from 11 eyes of 11 healthy subjects, using SS-OCT. The aqueous outflow pathway was identified using an en face OCT image and reconstructed images of the vasculature (vasculature map)...
August 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27472515/tarantula-hair-associated-panuveitis-treated-with-sustained-release-intravitreal-dexamethasone-implant
#17
Melina I Morkin, Lana M Rifkin, Sabin Dang, Caroline R Baumal
PURPOSE: To report a case of tarantula hair-induced panuveitis treated with sustained-release intravitreal dexamethasone implant and followed by sequential spectral domain optical coherence tomography imaging. METHODS: Findings on clinical examination, anterior segment optical coherence tomography, corneal in vivo confocal microscopy, color fundus photos, fluorescein angiography, and retinal spectral domain optical coherence tomography are presented. Sequential optical coherence tomography images demonstrated the course of the chorioretinal lesions before and after sustained-release intravitreal dexamethasone implant...
July 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27457079/-revision-surgery-in-episcleral-glaucoma-drainage-devices
#18
A Rosentreter, T S Dietlein
Episcleral glaucoma drainage devices (e.g., Ahmed or Baerveldt drainage device) are often used at a late stage in the care of glaucoma patients. At this stage other surgical techniques, such as trabeculectomy or viscocanaloplasty, have failed. However, the trend towards earlier implant surgery is supported by large randomized trials. Physicians should be aware of typical complications and, if possible, these should already be avoided by careful surgical technique. In this review article, we focus on postoperative hypotension, postoperative pressure increases, implant exposure, and possible corneal decompensation...
July 25, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27442322/ocular-manifestations-of-inherited-phospholipase-c%C3%AE-2-associated-antibody-deficiency-and-immune-dysregulation
#19
Antonio Di Zazzo, Maryam Tahvildari, George J Florakis, Reza Dana
PURPOSE: To report the ocular manifestations of phospholipase-Cγ2-associated antibody deficiency and immune dysregulation (PLAID). METHODS: Case report and literature review. RESULTS: A 21-year-old woman diagnosed with PLAID was referred for evaluation of repeated episodes of ocular inflammation resulting in bilateral peripheral corneal pannus with episcleritis and corneal scarring accompanied by systemic manifestations including epidermolysis bullosa and interstitial lung disease...
July 20, 2016: Cornea
https://www.readbyqxmd.com/read/27442321/primary-simple-limbal-epithelial-transplantation-along-with-excisional-biopsy-in-the-management-of-extensive-ocular-surface-squamous-neoplasia
#20
Vikas Mittal, Purvasha Narang, Vikas Menon, Ruchi Mittal, Santosh Honavar
PURPOSE: To describe the utility of simple limbal epithelial transplantation (SLET) along with tumor excision in the management of extensive ocular surface squamous neoplasia (OSSN) to avoid limbal stem cell deficiency (LSCD). METHODS: This case report describes the management of a 75-year-old man clinically diagnosed with OSSN involving more than 3 quadrants of limbus. The excisional biopsy of tumor along with 4-mm healthy margin led to a complete loss of the limbus, which was restored by limbal epithelial cell transplantation using the SLET technique in the same setting...
July 20, 2016: Cornea
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