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https://www.readbyqxmd.com/read/28229470/the-incidence-of-inflammatory-bowel-disease-in-denmark-1980-2013-a-nationwide-cohort-study
#1
S N Lophaven, E Lynge, J Burisch
BACKGROUND: Globally, the incidence rates of inflammatory bowel disease (IBD) are increasing; however, data from high-incidence areas are conflicting. Previous studies in Denmark have assessed incidence rates of Crohn's disease (CD) and ulcerative colitis (UC) using short observation periods. AIM: To investigate trends in IBD incidence in Denmark over a thirty-year period using nationwide data. METHODS: Patients diagnosed with CD or UC in Denmark between 1980 and 2013 were identified in the Danish National Patient Registry (NPR) and included in a nationwide cohort...
February 23, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28228656/incidence-and-long-term-outcome-of-severe-asthma-copd-overlap-compared-to-asthma-and-copd-alone-a-35-year-prospective-study-of-57-053-middle-aged-adults
#2
Camilla Boslev Baarnes, Zorana Jovanovic Andersen, Anne Tjønneland, Charlotte Suppli Ulrik
BACKGROUND: Incidence and prognosis for severe asthma-COPD overlap is poorly characterized. We investigated incidence and long-term outcome for patients with asthma-COPD overlap compared to asthma and COPD alone. MATERIALS AND METHODS: A total of 57,053 adults (aged 50-64 years) enrolled in the Danish Diet, Cancer, and Health cohort (1993-1997) were followed in the National Patients Registry for admissions for asthma (DJ45-46) and COPD (DJ40-44) and vital status...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28225200/alcohol-dependence-and-risk-of-somatic-diseases-and-mortality-a-cohort-study-in-19-002-men-and-women-attending-alcohol-treatment
#3
Charlotte Holst, Janne Schurmann Tolstrup, Holger Jelling Sørensen, Ulrik Becker
AIMS: To (1) estimate sex-specific risks of a comprehensive spectrum of somatic diseases in alcohol dependent individuals versus a control population, and in the same population to (2) estimate sex-specific risks of dying from the examined somatic diseases. DESIGN: Register-based matched cohort study. Alcohol dependent individuals were identified from an alcohol treatment database. Controls were randomly selected from the Danish Civil Registration System. Information on somatic diseases obtained from the Danish National Patient Registry and causes of death obtained from the Cause of Death Registry...
February 22, 2017: Addiction
https://www.readbyqxmd.com/read/28223847/evaluation-of-icd-10-algorithms-to-identify-hypopituitary-patients-in-the-danish-national-patient-registry
#4
Agnethe Berglund, Morten Olsen, Marianne Andersen, Eigil Husted Nielsen, Ulla Feldt-Rasmussen, Caroline Kistorp, Claus Højbjerg Gravholt, Kirstine Stochhholm
OBJECTIVE: Routinely collected health data may be valuable sources for conducting research. This study aimed to evaluate the validity of algorithms detecting hypopituitary patients in the Danish National Patient Registry (DNPR) using medical records as reference standard. STUDY DESIGN AND SETTING: Patients with International Classification of Diseases (10th edition [ICD-10]) diagnoses of hypopituitarism, or other diagnoses of pituitary disorders assumed to be associated with an increased risk of hypopituitarism, recorded in the DNPR during 2000-2012 were identified...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28221677/cardiovascular-disease-in-relation-to-placental-abruption-a%C3%A2-population-based-cohort-study-from-denmark
#5
Cande V Ananth, Anne Vinkel Hansen, Michelle A Williams, Anne-Marie Nybo Andersen
BACKGROUND: Cardiovascular (CVD) complications stemming from vascular dysfunction have been widely explored in the setting of preeclampsia. However, the impact of abruption, a strong indicator of microvascular disturbance, on the risk of CVD mortality and morbidity remains poorly characterised. METHODS: We designed a cohort analysis of 828 289 women who delivered singletons in Denmark between 1978 and 2010. We linked the National Patient Registry and the Registry of Causes of Death to the Danish Birth Registry to ascertain CVD events...
February 21, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28213739/does-influence-at-work-modify-the-relation-between-high-occupational-physical-activity-and-risk-of-heart-disease-in-women
#6
Karen Allesøe, Andreas Holtermann, Reiner Rugulies, Mette Aadahl, Eleanor Boyle, Karen Søgaard
PURPOSE: To investigate whether influence at work modifies the association between demanding and strenuous occupational physical activity (OPA) and risk of ischaemic heart disease (IHD). METHODS: A sample of 12,093 nurses aged 45-64 years from the Danish Nurse Cohort Study was followed for 20.6 years by individual linkage to incident IHD in the Danish National Patient Registry. Information on OPA, influence at work, other occupational factors and known risk factors for IHD was collected by self-report in 1993...
February 17, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28187995/validity-of-peripheral-arterial-disease-diagnoses-in-the-danish-national-patient-registry
#7
A N Lasota, K Overvad, H H Eriksen, A Tjønneland, E B Schmidt, M-L M Grønholdt
OBJECTIVES/BACKGROUND: The objective was to validate the diagnoses of peripheral arterial disease (PAD) in the legs, obtained from national registers in Denmark. METHODS: In total, 1435 registered cases of PAD were identified in the Danish National Patient Registry among 57,053 middle aged participants from the Danish Diet, Cancer and Health cohort study. Validation was performed by reviewing all medical records using pre-specified criteria for a diagnosis of PAD...
February 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28182643/ige-sensitization-to-inhalant-allergens-and-the-risk-of-airway-infection-and-disease-a-population-based-study
#8
Tea Skaaby, Lise Lotte Nystrup Husemoen, Betina Heinsbæk Thuesen, Runa Vavia Fenger, Allan Linneberg
BACKGROUND: Immunoglobulin E (IgE) sensitization, which is the propensity to develop IgE antibodies against common environmental allergens, is associated with a lymphocyte T-helper type 2 (Th2) skewed immune response and a high risk of allergic respiratory disease. Little is known about whether IgE sensitization confers an increased risk of respiratory infections in adults. We investigated the association between IgE sensitization and the incidence of acute airway infections, other infections and chronic lower airway disease events as recorded in nation-wide registries...
2017: PloS One
https://www.readbyqxmd.com/read/28179451/cushing-s-syndrome-in-children-and-adolescents-a-danish-nationwide-population-based-cohort-study
#9
Johanne Marie Holst, Erzsébet Horváth-Puhó, Rb Jensen, Mariane Rix, Niels Thomas Hertel, Olaf Dekkers, Henrik Toft Sørensen, Anders Juul, Jens Otto L Jorgensen
OBJECTIVE: Cushing's syndrome (CS) affects all age groups, but epidemiologic data in young pa-tients are very limited. We therefore examined the incidence, prevalence, and hospital morbidity of CS in children and adolescents. DESIGN: In a nationwide cohort study we included all Danish citizens aged 0-20 years from 1977 to 2012. Data were obtained from the Danish National Patient Registry using the International Classi-fication of Diseases (ICD) codes and the Danish Civil Registration System...
February 8, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28173795/good-life-with-osteoarthritis-in-denmark-gla-d%C3%A2-evidence-based-education-and-supervised-neuromuscular-exercise-delivered-by-certified-physiotherapists-nationwide
#10
Søren T Skou, Ewa M Roos
BACKGROUND: The uptake of evidence-based guidelines in clinical practice is suboptimal in osteoarthritis (OA) and other chronic diseases. Good Life with osteoArthritis in Denmark (GLA:D) was launched in 2013 with the aim of implementing guidelines for the treatment of knee and hip OA in clinical care nationwide. The purpose of this report was to evaluate the effects of the GLA:D intervention from 2013 to 2015, using data from the national GLA:D registry. METHODS: Patients undergo education and supervised exercise delivered by trained physiotherapists...
February 7, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28173172/data-resource-profile-the-danish-national-prescription-registry
#11
Anton Pottegård, Sigrun Alba Johannesdottir Schmidt, Helle Wallach-Kildemoes, Henrik Toft Sørensen, Jesper Hallas, Morten Schmidt
No abstract text is available yet for this article.
October 26, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28153208/morbidity-of-childhood-onset-narcolepsy-a-controlled-national-study
#12
Poul Jennum, Line Pickering, Eva Wiberg Thorstensen, Rikke Ibsen, Jakob Kjellberg
: Narcolepsy is associated with significant morbidities. We evaluated the morbidities and mortality in a national group of child and adolescent patients after a first diagnosis of narcolepsy. METHODS: Identified from the Danish National Patient Registry (NPR), 243 patients (128 boys) aged 0-19 years diagnosed with narcolepsy between 1998 and 2012 with follow-up until 2014 were compared with 970 controls who were randomly chosen from the Danish Civil Registration System Statistics and matched by age, gender and geography...
January 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28152633/long-term-mortality-after-poisoning-with-antipsychotics
#13
Stine Toft, Henrik Horwitz, Kim Peder Dalhoff
INTRODUCTION: The objective of this study was to investigate the long-term mortality and cause of death after deliberate self-poisoning with antipsychotics. Furthermore, we investigated the risk of repeated self-poisoning after a first episode of poisoning with antipsychotics. METHODS: We identified patients with antipsychotic poisoning from the Danish Poison Information Centre Database and correlated their personal identification number with four Danish national registries related to health aspects...
February 3, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28135773/epidemiological-study-of-paediatric-germ-cell-tumours-revealed-the-incidence-and-distribution-that-was-expected-but-a-low-mortality-rate
#14
Madeline Evers, Catherine Rechnitzer, Niels Graem, Peder Skov Wehner, Henrik Schroeder, Steen Rosthoej, Christiane Hammershaimb Mosbech, Christina Engel Hoei-Hansen, Astrid Sehested, Taryn D Treger, Jesper Brok
AIM: Germ cell tumours (GCTs) are a rare heterogeneous tumour group derived from primordial germ cells, which can be benign or malignant and occur in the gonads or extragonadally. This study mapped the paediatric GCTs in Denmark from 1984-2013 to study the incidence and outcome. METHODS: We identified paediatric GCTs from the Danish Childhood Cancer and National Pathology Registries and reviewed the case records for patient characteristics, tumour characteristics and clinical outcome...
January 30, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28135041/inflammatory-bowel-disease-and-venous-thromboembolism-during-pregnancy-and-the-postpartum-period
#15
Anette Tarp Hansen, Rune Erichsen, Erzsébet Horváth-Puhó, Henrik Toft Sørensen
BACKGROUND: The incidence of inflammatory bowel disease (IBD) increases, thus becoming more common also among pregnant women. IBD is a risk factor for venous thromboembolism (VTE), but it is not clear whether IBD infers an excess risk of VTE during pregnancy and the postpartum period. METHODS: A nationwide population-based cohort study of all deliveries during 1980-2013 in Denmark, using data from two nationwide health registries: the Danish National Patient Registry and the Medical Birth Registry...
January 30, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28107257/perceived-stress-as-a-risk-factor-for-dyspepsia-a-register-based-cohort-study
#16
Ulrik Deding, Christian Torp-Pedersen, Henrik Bøggild
OBJECTIVE: Dyspepsia is a common condition and has a huge impact on quality of life and working capacity, but its causes are not well understood. An association between stress and dyspepsia has been debated for decades, but the issue has not been resolved. We examined the 3-year risk of redeeming a proton-pump inhibitor or an H2-receptor antagonist as a proxy of dyspepsia according to the level of perceived stress. PARTICIPANTS AND METHODS: Perceived stress was measured in a general health survey of 16 124 Danes aged older than 16 years of age in 2010 using Cohen's Perceived Stress Scale...
January 21, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28103712/endogenous-and-antipsychotic-related-risks-for-diabetes-mellitus-in-young-people-with-schizophrenia-a-danish-population-based-cohort-study
#17
Anto P Rajkumar, Henriette Thisted Horsdal, Theresa Wimberley, Dan Cohen, Ole Mors, Anders D Børglum, Christiane Gasse
OBJECTIVE: Diabetes mellitus contributes to excessive cardiovascular deaths and reduced life expectancy in schizophrenia. This population-based cohort study investigated the endogenous risk for diabetes in antipsychotic-naive schizophrenia and evaluated the risks added by starting antipsychotic treatment in people with schizophrenia. METHOD: The study followed all people born in Denmark on or after Jan. 1, 1977, until Jan. 1, 2013 (N=2,736,510). The Danish Psychiatric Central Research Register ascertained schizophrenia diagnoses...
January 20, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28077059/ignorance-is-not-bliss-the-effect-of-systematic-information-on-immigrants-knowledge-of-and-satisfaction-with-the-danish-healthcare-system
#18
Signe Smith Jervelund, Thomas Maltesen, Camilla Lawaetz Wimmelmann, Jørgen Holm Petersen, Allan Krasnik
AIMS: Suboptimal healthcare utilisation and lower satisfaction with the patient-doctor encounter among immigrants has been documented. Immigrants' lack of familiarity with the healthcare system has been proposed as an explanation for this. This study investigated whether a systematic delivery of information affected immigrants' knowledge of and satisfaction with the Danish healthcare system. METHODS: A prospective, randomised intervention study of 1158 adult immigrants attending two language schools in Copenhagen was conducted...
2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28065667/a-large-frontal-qrs-t-angle-is-a-strong-predictor-of-the-long-term-risk-of-myocardial-infarction-and-all-cause-mortality-in-the-diabetic-population
#19
Ole May, Christina Boesgaard Graversen, Mia Østergaard Johansen, Hanne Arildsen
BACKGROUND: A large angle between the QRS vector and the T-wave vector (QRS-T angle) in electrocardiograms (ECGs) has recently been introduced as a marker of poor prognosis. The prognostic value in diabetes is unknown. We assessed the long-term predictive power of the frontal plane QRS-T angle in the diabetic population. METHODS: In 1992-93, the diabetic population of the municipality of Horsens, Denmark, was delineated by the prescription method, and an age- and gender-stratified sample of 240 diabetic persons was randomly selected...
December 16, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28061841/supervised-neuromuscular-exercise-prior-to-hip-and-knee-replacement-12-month-clinical-effect-and-cost-utility-analysis-alongside-a-randomised-controlled-trial
#20
Linda Fernandes, Ewa M Roos, Søren Overgaard, Allan Villadsen, Rikke Søgaard
BACKGROUND: There are indications of beneficial short-term effect of pre-operative exercise in reducing pain and improving activity of daily living after total hip replacement (THR) and total knee replacement (TKR) surgery. Though, information from studies conducting longer follow-ups and economic evaluations of exercise prior to THR and TKR is needed. The aim of the study was to analyse 12-month clinical effect and cost-utility of supervised neuromuscular exercise prior to THR and TKR surgery...
January 6, 2017: BMC Musculoskeletal Disorders
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