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https://www.readbyqxmd.com/read/28432995/eye-disorder-differentiates-seasonality-outcomes-in-persons-with-severe-visual-impairment
#1
Heller Madsen, Henrik Dam, Ida Hageman
BACKGROUND: Light plays a crucial role in both the pathogenesis and treatment of seasonal affective disorder (SAD). Consequently decreased retinal sensitivity to light has been suggested to be a risk factor for SAD. In a population of persons with severe visual impairment we recently found a highly increased prevalence of SAD. We now aimed to identify eye disorders or anatomical locations with specific association to seasonality. METHODS: In 912 cases (33%) from our prior seasonal pattern assessment questionnaire (SPAQ) screening study, we retrieved eye diagnoses from the Danish National Patient Registry and analyzed for specific eye disorders or anatomical locations that significantly differentiated SPAQ outcomes (global seasonality score, (GSS) and SPAQ-SAD prevalence)...
April 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28429106/occupational-exposure-to-extremely-low-frequency-magnetic-fields-and-risk-for-central-nervous-system-disease-an-update-of-a-danish-cohort-study-among-utility-workers
#2
Camilla Pedersen, Aslak Harbo Poulsen, Naja Hulvej Rod, Patrizia Frei, Johnni Hansen, Kathrine Grell, Ole Raaschou-Nielsen, Joachim Schüz, Christoffer Johansen
PURPOSE: Evidence of whether exposure to extremely low-frequency magnetic fields (ELF-MF) is related to central nervous system diseases is inconsistent. This study updates a previous study of the incidence of such diseases in a large cohort of Danish utility workers by almost doubling the period of follow-up. METHODS: We investigated the risks for dementia, motor neurone disease, Parkinson disease, multiple sclerosis and epilepsy among 32,006 men employed at the 99 utility companies that supplied Denmark with electricity during the period 1900-1993...
April 20, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28422885/cancer-of-unknown-primary-registered-procedures-compared-with-national-integrated-cancer-pathway-for-illuminating-external-validity
#3
Anne-Kirstine Dyrvig, Knud Bonnet Yderstræde, Oke Gerke, Peter Bjødstrup Jensen, Søren Hess, Poul Flemming Høilund-Carlsen, Anders Green
Cancer of unknown primary (CUP) ranges within top 10 cancers in both incidence and mortality. As primary identification is crucial to choosing treatment, guidelines on CUP emphasize the diagnostic strategy. Whether guidelines are complied with, or if they are indeed helpful, is however unclear. We compared procedures performed in suspected CUP patients with recommendations of national guidelines to assess external validity of guidelines.The Danish National Patient Registry (NPR) comprising population data was utilized to identify the suspected CUP patients during 2009 to 2010 and explore exposure to procedures and patient survival...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28409235/anal-incontinence-after-two-vaginal-deliveries-without-obstetric-anal-sphincter-rupture
#4
Lisa K G Persson, Abelone Sakse, Jens Langhoff-Roos, Hanna Jangö
PURPOSE: To evaluate prevalence and risk factors for long-term anal incontinence in women with two prior vaginal deliveries without obstetric anal sphincter injury (OASIS) and to assess the impact of anal incontinence-related symptoms on quality of life. METHODS: This is a nation-wide cross-sectional survey study. One thousand women who had a first vaginal delivery and a subsequent delivery, both without OASIS, between 1997 and 2008 in Denmark were identified in the Danish Medical Birth Registry...
April 13, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28401355/correlation-between-early-surgical-complications-and-readmission-rate-after-ventral-hernia-repair
#5
D Kokotovic, H Sjølander, I Gögenur, F Helgstrand
PURPOSE: Postoperative surgical complications arising from ventral hernia repair have been assessed by a variety of outcome measures. The objective of this study was to correlate the Clavien Dindo Classification (CDC) graded complications with the 30-day readmission rate as early outcome measures in ventral hernia repair. Secondarily, we wanted to investigate whether the risk factors for Clavien Dindo class ≥1 and 30-day readmission were comparable. METHODS: Single-centre retrospective study including all patients (≥18 years) who underwent ventral hernia repair between January 1, 2009 and September 1, 2014 at Zealand University Hospital...
April 11, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28393739/prenatal-exposure-to-vitamin-d-from-fortified-margarine-and-risk-of-fractures-in-late-childhood-period-and-cohort-results-from-222-000-subjects-in-the-d-tect-observational-study
#6
Mina Nicole Händel, Peder Frederiksen, Clive Osmond, Cyrus Cooper, Bo Abrahamsen, Berit L Heitmann
Prenatal low vitamin D may have consequences for bone health. By means of a nationwide mandatory vitamin D fortification programme, we examined the risk of fractures among 10-18-year-old children from proximate birth cohorts born around the date of the termination of the programme. For all subjects born in Denmark during 1983-1988, civil registration numbers were linked to the Danish National Patient Registry for incident and recurrent fractures occurring at ages 10-18 years. Multiplicative Poisson models were used to examine the association between birth cohort and fracture rates...
April 10, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28392715/positive-predictive-values-of-international-classification-of-diseases-10th-revision-codes-for-dermatologic-events-and-hypersensitivity-leading-to-hospitalization-or-emergency-room-visit-among-women-with-postmenopausal-osteoporosis-in-the-danish-and-swedish
#7
Kasper Adelborg, Lotte Brix Christensen, Troels Munch, Johnny Kahlert, Ylva Trolle Lagerros, Grethe S Tell, Ellen M Apalset, Fei Xue, Vera Ehrenstein
BACKGROUND: Clinical epidemiology research studies, including pharmacoepidemiology and pharmacovigilance studies, use routinely collected health data, such as diagnoses recorded in national health and administrative registries, to assess clinical effectiveness and safety of treatments. We estimated positive predictive values (PPVs) of International Classification of Diseases, 10th revision (ICD-10) codes for primary diagnoses of dermatologic events and hypersensitivity recorded at hospitalization or emergency room visit in the national patient registries of Denmark and Sweden among women with postmenopausal osteoporosis (PMO)...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28389225/prognosis-of-asymptomatic-and-symptomatic-undiagnosed-copd-in-the-general-population-in-denmark-a-prospective-cohort-study
#8
Yunus Çolak, Shoaib Afzal, Børge G Nordestgaard, Jørgen Vestbo, Peter Lange
BACKGROUND: COPD can be diagnosed early using spirometry, but spirometry use is only recommended in symptomatic smokers, even though early stages of COPD can be asymptomatic. We investigated the prognosis of individuals with asymptomatic and symptomatic, undiagnosed COPD in the general population in Denmark. METHODS: In this prospective cohort study, we analysed data from 95 288 individuals aged 20-100 years from the Copenhagen General Population Study. 32 518 (34%) of these individuals were regarded as being at high risk for COPD (defined as individuals aged 40 years or older, with cumulative tobacco consumption of ten pack-years or higher, and without self-reported or a previous hospital contact for asthma)...
April 4, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28383449/differential-impact-of-anastomotic-leak-in-patients-with-stage-iv-colonic-or-rectal-cancer-a-nationwide-cohort-study
#9
Andreas Nordholm-Carstensen, Hans Christian Rolff, Peter-Martin Krarup
BACKGROUND: Anastomotic leak has a negative impact on the prognosis of patients who undergo colorectal cancer resection. However, data on anastomotic leak are limited for stage IV colorectal cancers. OBJECTIVE: The purpose of this study was to investigate the impact of anastomotic leak on survival and the decision to administer chemotherapy and/or metastasectomy after elective surgery for stage IV colorectal cancer. DESIGN: This was a nationwide, retrospective cohort study...
May 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28365142/risk-of-heart-disease-in-relation-to-radiotherapy-and-chemotherapy-with-anthracyclines-among-19-464-breast-cancer-patients-in-denmark-1977-2005
#10
Jens Christian Rehammar, Maj-Britt Jensen, Paul McGale, Ebbe Laugaard Lorenzen, Carolyn Taylor, Sarah C Darby, Lars Videbæk, Zhe Wang, Marianne Ewertz
BACKGROUND AND PURPOSE: The risk of heart disease subsequent to breast cancer radiotherapy was examined with particular focus on women receiving anthracycline-containing chemotherapy. MATERIAL AND METHODS: Women diagnosed with early-stage breast cancer in Denmark, 1977-2005, were identified from the register of the Danish Breast Cancer Cooperative Group, as was information on cancer-directed treatment. Information on heart disease was sought from the Danish National Patient and Cause of Death Registries...
March 29, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28356140/clinical-course-and-prognosis-of-musculoskeletal-pain-in-patients-referred-for-physiotherapy-does-pain-site-matter
#11
Nils-Bo de Vos Andersen, Peter Kent, Jakob Hjort, David Høyrup Christiansen
BACKGROUND: Danish patients with musculoskeletal disorders are commonly referred for primary care physiotherapy treatment but little is known about their general health status, pain diagnoses, clinical course and prognosis. The objectives of this study were to 1) describe the clinical course of patients with musculoskeletal disorders referred to physiotherapy, 2) identify predictors associated with a satisfactory outcome, and 3) determine the influence of the primary pain site diagnosis relative to those predictors...
March 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28350746/perceived-stress-as-a-risk-factor-for-dyspepsia-a-register-based-cohort-study
#12
Ulrik Deding, Christian Torp-Pedersen, Henrik Bøggild
OBJECTIVE: Dyspepsia is a common condition and has a huge impact on quality of life and working capacity, but its causes are not well understood. An association between stress and dyspepsia has been debated for decades, but the issue has not been resolved. We examined the 3-year risk of redeeming a proton-pump inhibitor or an H2-receptor antagonist as a proxy of dyspepsia according to the level of perceived stress. PARTICIPANTS AND METHODS: Perceived stress was measured in a general health survey of 16 124 Danes aged older than 16 years of age in 2010 using Cohen's Perceived Stress Scale...
May 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28348022/increase-in-thyroglobulin-antibody-and-thyroid-peroxidase-antibody-levels-but-not-preterm-birth-rate-in-pregnant-danish-women-upon-iodine-fortification
#13
Sofie Bliddal, Malene Boas, Linda Hilsted, Lennart Friis-Hansen, Anders Juul, Torben Larsen, Ann Tabor, Jens Faber, Dorthe Hansen Precht, Ulla Feldt-Rasmussen
OBJECTIVE: The presence of thyroid antibodies in pregnancy has been associated with preterm birth. In the non-pregnant population, the implementation of the Danish iodine fortification program has increased the prevalence of thyroid antibodies. This study investigated the prevalence of thyroid peroxidase antibodies (TPOAbs) and thyroglobulin antibodies (TgAbs) in pregnant Danish women before, during and after implementation of the iodine fortification program and association with preterm birth...
May 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28343459/a-retrospective-analysis-of-a-societal-experiment-among-the-danish-population-suggests-that-exposure-to-extra-doses-of-vitamin-a-during-fetal-development-may-lower-type-2-diabetes-mellitus-t2dm-risk-later-in-life
#14
Amélie Keller, Lars Ängquist, Ramune Jacobsen, Allan Vaag, Berit L Heitmann
Vitamin A deficiency has been associated with impaired fetal pancreatic development and increased risk of developing type 2 diabetes mellitus (T2DM). In 1962, mandatory margarine fortification with vitamin A was increased by 25 % in Denmark. We aimed to determine whether offspring of mothers who had been exposed to the extra vitamin A from fortification during pregnancy had a lower risk of developing T2DM in adult life, compared with offspring of mothers exposed to less vitamin A. Individuals from birth cohorts with the higher prenatal vitamin A exposure (born 1 December 1962-31 March 1964) and those with lower prenatal exposure (born 1 September 1959-31 December 1960) were followed up with regard to development of T2DM before 31 December 2012 in the Danish National Diabetes Registry and National Patient Register...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28339674/family-history-of-systemic-lupus-erythematosus-and-risk-of-autoimmune-disease-nationwide-cohort-study-in-denmark-1977-2013
#15
Constance Jensina Ulff-Møller, Jacob Simonsen, Kirsten Ohm Kyvik, Søren Jacobsen, Morten Frisch
Objective.: To provide population-based estimates of relative risk of SLE and other autoimmune diseases (ADs) in relatives of SLE patients. Methods.: A cohort of 5 237 319 Danish residents identified through the Civil Registration System was coupled to their relatives through the parental link and followed for SLE and other ADs between 1977 and 2013 through linkage to the National Patient Register. Twin zygosity was established through the Danish Twin Registry. Hazard ratios (HRs) with 95% CIs were calculated using Cox proportional hazards regression analyses...
February 20, 2017: Rheumatology
https://www.readbyqxmd.com/read/28337731/arthroplasty-registries-around-the-world-valuable-sources-of-hip-implant-revision-risk-data
#16
REVIEW
Richard E Hughes, Aditi Batra, Brian R Hallstrom
PURPOSE OF REVIEW: National and regional arthroplasty registries have proliferated since the Swedish Knee Arthroplasty Register was started in 1975. Registry reports typically present implant-specific estimates of revision risk and patient- and technique-related factors that can inform clinical decision-making about implants and techniques. However, annual registry reports are long and it is difficult for clinicians to extract comparable revision risk data. Since implants may appear in multiple registry reports, it is even more difficult to gather relevant data for clinical decision-making about implant selection...
March 23, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28334645/long-term-residential-road-traffic-noise-and-no2-exposure-in-relation-to-risk-of-incident-myocardial-infarction-a-danish-cohort-study
#17
Nina Roswall, Ole Raaschou-Nielsen, Matthias Ketzel, Anders Gammelmark, Kim Overvad, Anja Olsen, Mette Sørensen
BACKGROUND: Road traffic is a source of both air pollution and noise; two environmental hazards both found to increase the risk of ischemic heart disease. Given the high correlation between these pollutants, it is important to investigate combined effects, in relation to myocardial infarction (MI). METHODS: Among 50,744 middle-aged Danes enrolled into the Diet, Cancer and Health cohort from 1993 to 97, we identified 2403 cases of incident MI during a median follow-up of 14...
March 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28330507/is-admittance-to-specialised-palliative-care-among-cancer-patients-related-to-sex-age-and-cancer-diagnosis-a-nation-wide-study-from-the-danish-palliative-care-database-dpd
#18
Mathilde Adsersen, Lau Caspar Thygesen, Anders Bonde Jensen, Mette Asbjoern Neergaard, Per Sjøgren, Mogens Groenvold
BACKGROUND: Specialised palliative care (SPC) takes place in specialised services for patients with complex symptoms and problems. Little is known about what determines the admission of patients to SPC and whether there are differences in relation to institution type. The aims of the study were to investigate whether cancer patients' admittance to SPC in Denmark varied in relation to sex, age and diagnosis, and whether the patterns differed by type of institution (hospital-based palliative care team/unit, hospice, or both)...
March 23, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28324016/cardiorespiratory-fitness-and-adiposity-as-determinants-of-metabolic-health-pooled-analysis-of-two-twin-cohorts
#19
Sakari Jukarainen, René Holst, Christine Dalgård, Päivi Piirilä, Jesper Lundbom, Antti Hakkarainen, Nina Lundbom, Aila Rissanen, Jaakko Kaprio, Kirsten Ohm Kyvik, Thorkild I A Sørensen, Kirsi H Pietiläinen
Context: The joint effects of cardiorespiratory fitness and body composition on metabolic health are not well known. Objective: To examine the associations of cardiorespiratory fitness (CRF), fat free mass index (FFMI) and fat mass index (FMI) with metabolic health in individual twins and controlling for genetic and shared environmental effects by studying monozygotic intrapair differences. Design, setting & participants: Two cross-sectional samples of healthy adult monozygotic and dizygotic twins were drawn from population-based Danish and Finnish national twin registries (n=996 and n=309)...
January 23, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28317581/radical-prostatectomy-in-denmark-survival-analysis-and-temporal-trends-in-clinicopathological-parameters-with-up-to-20-years-of-follow-up
#20
Mikael Heering, Kasper Drimer Berg, Klaus Brasso, Peter Iversen, Martin Andreas Røder
OBJECTIVES: To describe mortality, cause of death, and temporal trends in clinicopathological parameters with up to 20 years of follow-up in a nationwide cohort of prostate cancer (PCa) patients who underwent radical prostatectomy (RP). MATERIALS AND METHODS: A total of 6857 patients with PCa treated with RP at six different hospitals in Denmark between 1995 and 2011. Data were extracted from the nationwide DaPCa database. Histopathology reports from the RP specimens were manually reviewed...
March 2017: Surgical Oncology
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