Isabel Cornejo-Pareja, Gracia M Martín-Núñez, M Mar Roca-Rodríguez, Fernando Cardona, Leticia Coin-Aragüez, Lidia Sánchez-Alcoholado, Carolina Gutiérrez-Repiso, Araceli Muñoz-Garach, José C Fernández-García, Isabel Moreno-Indias, Francisco J Tinahones
Changes in the intestinal microbial community and some metabolic disturbances, including obesity and type2 diabetes, are related. Glucagon-like peptide-1 (GLP-1) regulates glucose homeostasis. Microbiota have been linked to incretin secretion. Antibiotic use causes changes in microbial diversity and composition. Our aim was to evaluate the relationship between microbiota changes and GLP-1 secretion. A prospective case-control study with a Helicobacter pylori -positive patient model involving subjects under eradication therapy (omeprazole, clarithromycin, and amoxicillin)...
April 4, 2019: Journal of Clinical Medicine