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https://www.readbyqxmd.com/read/26113359/borderline-tuberculoid-leprosy-in-childhood-onset-systemic-lupus-erythematosus-patient
#1
V A P Lopes, D M R Lourenço, A Guariento, M A Trindade, J Avancini, C A Silva
Leprosy is a contagious and chronic systemic granulomatous disease caused by the bacillus Mycobacterium leprae. To our knowledge, no case of leprosy in a childhood-onset systemic lupus erythematosus (c-SLE) patient has been reported. For a period of 31 years, 312 c-SLE patients were followed at the Pediatric Rheumatology Unit of our University Hospital. One of them (0.3%) had tuberculoid leprosy skin lesions during the disease course and is here reported. A 10-year-old boy from Northwest of Brazil was diagnosed with c-SLE based on malar rash, photosensitivity, oral ulcers, lymphopenia, proteinuria, positive antinuclear antibodies, anti-double-stranded DNA, anti-Sm and anti-Ro/SSA autoantibodies...
November 2015: Lupus
https://www.readbyqxmd.com/read/22242681/radiofrequency-ablation-does-not-induce-apoptosis-in-the-rat-myocardium
#2
Luis F Dos Santos, Ednei Antonio, Andrey Serra, Gabriela Venturini, Mieko Okada, Sergio Araújo, Paulo Tucci, Angelo De Paola, Guilherme Fenelon
BACKGROUND: The mechanisms implicated in the genesis of delayed radiofrequency (RF) effects remain unclear, but may be related to extension of the lesion beyond the region of coagulative necrosis. The role of apoptosis in this process has not been previously reported. We assessed whether RF promotes apoptosis in the region surrounding acute ablation lesions in a rat model. METHODS: Wistar rats (n=30; weight 300 g) were anesthesized, the chest was opened, and the heart was exposed...
April 2012: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/21912009/trends-in-intraoperative-pain-relief-in-anesthesized-nigerian-pediatric-patients-implications-for-a-developing-economy
#3
O P Adudu, I Isa, F O Longway
BACKGROUND: New drugs and new modalities for intraoperative pain relief is the current trend in pain management. Aim : The study aims at examining the current trend in intraoperative pain relief in patients of pediatric age at the University of Benin Teaching Hospital (UBTH) and its implications for a developing economy such as Nigeria. MATERIALS AND METHODS: A retrospective study of 652 patients of pediatric age undergoing various surgical procedures was carried out in UBTH, Nigeria from January 2006 to June 2008...
July 2011: Annals of African Medicine
https://www.readbyqxmd.com/read/20549096/-oral-cancer-surgery-and-oral-cutaneous-fistulas-risk-factors
#4
Gyl Henrique A Ramos, André Luiz Soares Crivelaro, Benedito Valdecir de Oliveira, Paola Andrea G Pedruzzi, Rosyane Rena de Freitas
OBJECTIVE: To quantify the oral cutaneous fistulae after surgery and to identify possible risk factors. METHODS: A retrospective study, interesting patients that were submitted to surgery, with a two years minimum post-operative follow up. The considered variables were: sex, concomitant diseases, tabacco and alcohol use, the anesthesic and pulmonary risks, clinical stage, cervical linphadenectomy, pre or postoperative radiotherapy, accidents during the surgery, wound infection and or hematoma, pulmonary infection, surgery and reconstruction extension...
April 2010: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/20079609/excessive-bleeding-in-the-floor-of-the-mouth-after-endosseus-implant-placement-a-report-of-two-cases
#5
L Dubois, J de Lange, E Baas, J Van Ingen
Placement of dental implants in the interforaminal region of the edentulous mandible is considered a safe and routine surgical procedure. Hemorrhage in the floor of the mouth has been reported as a rare, potentially life-threatening complication related to the placement of implants in this region. In this case report the authors present an immediate and a delayed case of massive bleeding in the floor of the mouth after implant placement. This highly vascularized region is vulnerable and bleeding can be induced easily by instrumentation, causing a vascular trauma, usually by perforation of lingual periostium...
April 2010: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/18158953/anesthesia-condition-for-18-f-fdg-imaging-of-lung-metastasis-tumors-using-small-animal-pet
#6
Sang-Keun Woo, Tae Sup Lee, Kyeong Min Kim, June-Youp Kim, Jae Ho Jung, Joo Hyun Kang, Gi Jeong Cheon, Chang Woon Choi, Sang Moo Lim
UNLABELLED: Small animal positron emission tomography (PET) with (18)F-FDG has been increasingly used for tumor imaging in the murine model. The aim of this study was to establish the anesthesia condition for imaging of lung metastasis tumor using small animal (18)F-FDG PET. METHODS: To determine the impact of anesthesia on (18)F-FDG distribution in normal mice, five groups were studied under the following conditions: no anesthesia, ketamine and xylazine (Ke/Xy), 0...
January 2008: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/17318899/low-level-accelerations-applied-in-the-absence-of-weight-bearing-can-enhance-trabecular-bone-formation
#7
Russell Garman, Glenn Gaudette, Leah-Rae Donahue, Clinton Rubin, Stefan Judex
High-frequency whole body vibrations can be osteogenic, but their efficacy appears limited to skeletal segments that are weight bearing and thus subject to the induced load. To determine the anabolic component of this signal, we investigated whether low-level oscillatory displacements, in the absence of weight bearing, are anabolic to skeletal tissue. A loading apparatus, developed to shake specific segments of the murine skeleton without the direct application of deformations to the tissue, was used to subject the left tibia of eight anesthesized adult female C57BL/6J mice to small (0...
June 2007: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/16724307/endothelin-a-receptor-antagonist-lu-302146-inhibits-electrostimulation-induced-bladder-contractions-in-vivo
#8
J R Scheepe, J van den Hoek, K P Jünemann, P Alken
OBJECTIVES: Endothelin (ET) is a strong constrictor of smooth muscle structures. The relevance of Endothelin-A receptors in the bladder was demonstrated in several in vitro studies. The aim of this functional study was to evaluate the acute effect of the selective ET-A-antagonist LU 302146 (LU) on neurostimulation-induced bladder contractions in vivo. METHODS: Eight male mini pigs were anesthesized. The bladder was exposed and a double lumen catheter was inserted to perform intravesical pressure (pves) measurements...
2006: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/16720352/demonstration-of-a-physiologic-sphincter-at-duodeno-jejunal-junction
#9
Ahmed Shafik, Olfat El Sibai, Ali A Shafik, Ismail A Shafik
Current evidence suggests that there are three sphincters that regulate the flow of chyme from stomach to the duodenum. We investigated the hypothesis whether a fourth 'physiologic sphincter' exists at the duodeno-jejunal junction. The pressure response of the jejunum, duodeno-jejunal junction and duodenum to individual balloon distension of the jejunum and duodenum was recorded in 28 healthy subjected before and after anesthesizing the jejunum, duodeno-jejunal junction and duodenum. The duodeno-jejunal junction length was measured by the station pull-through technique...
2006: Frontiers in Bioscience: a Journal and Virtual Library
https://www.readbyqxmd.com/read/16646681/triiodothyronine-acutely-increases-blood-flow-in-the-ventricles-and-kidneys-of-anesthesized-rabbits
#10
Koji Kimura, Yoshiro Shinozaki, Sio Jujo, Toru Shizuma, Naoto Fukuyama, Hiroe Nakazawa
Thyroid hormone (triiodothyronine [T(3)]) has various nongenomic effects, including alterations in glucose and fatty acid metabolism, augmentation of intracellular Ca(2+), enhancement of myocardial contractility, and vascular dilatation. However, its effect on regional blood flow remains to be established. We have measured the effect of T(3) on blood flow in major organs of anesthetized rabbits in vivo using the microsphere method. Under artificial respiration, nonradioactive microspheres (5 x 10(5)) labeled with barium were injected to measure blood flow at control level...
April 2006: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/15947897/-corrective-osteotomy-of-the-humerus-using-perivascular-axillary-anesthesia-according-to-weber-in-a-patient-suffering-from-mccune-albright-syndrome
#11
V Bullmann, R Waurick, R Rödl, G Hülskamp, O Orlowski, H van Aken, W Winkelmann, T P Weber
We report on a 20-year-old patient with McCune-Albright syndrome suffering from global respiratory insufficiency who required continuous mask ventilation and where intubation had to be avoided. Perivascular axillary anesthesia according to Weber was performed for a double corrective osteotomy of the humerus. During plexus anesthesia the patient was positioned on the non-anesthesized side in a 15 degrees Trendelenburg position. An extension of analgesia was observed up to the complete upper arm region. Using the modified positioning an extension of brachial plexus anesthesia is possible...
September 2005: Der Anaesthesist
https://www.readbyqxmd.com/read/15602480/-effects-of-extrastimulation-on-morphofunctional-state-of-cochlear-stria-vascularis
#12
A I Kriukov, O V Veselago, M M Tanashian
An electron-microscopic study of the response of cochlear stria vascularis (CSV) cells to an electric impact of physiotherapeutic parameters was made in 26 guinea-pigs. Twelve guinea-pigs (group 1) have undergone 9 sessions of bilateral endaural electrostimulation with square bipolar impulses (4 ms, 0.1-0.4 mA, 50 Hz, 20 min). Fourteen guinea-pigs of group 2 have undergone a 12-18-day course of intramuscular ototoxic antibiotic canamycin in a dose 200-400 mg/day followed by the above electrostimulation. Nine anesthesized guinea-pigs of group 3 were inserted an electrode into the niche of the round window of the right ear...
2004: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/15331045/mechanisms-of-sustained-cutaneous-vasodilation-induced-by-spinal-cord-stimulation
#13
COMPARATIVE STUDY
Satoshi Tanaka, Naoka Komori, Kirk W Barron, Margaret J Chandler, Bengt Linderoth, Robert D Foreman
This study was performed to investigate whether spinal cord stimulation (SCS) at intensities below motor threshold prolongs cutaneous vasodilation and whether sustained vasodilation by SCS is mediated through sympathetic inhibition and/or antidromic activation of sensory fibers. SCS was applied to the dorsal surface of the L2-L3 spinal cord of anesthesized rats with stimulus parameters used clinically (i.e., 50 Hz, 0.2 ms duration, and stimulus intensity at 30%, 60%, or 90% of motor threshold). Peripheral vasodilation induced by 5-min SCS was not attenuated by hexamethonium, an autonomic ganglion-blocking agent, but was abolished by dorsal rhizotomy...
July 30, 2004: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/12419499/vasodilatation-of-muscle-microvessels-induced-by-somatic-afferent-stimulation-is-mediated-by-calcitonin-gene-related-peptide-release-in-the-rat
#14
Lázaro A Loaiza, Shinjiro Yamaguchi, Momoyo Ito, Norio Ohshima
In anesthesized rats, the effects of electrical stimulation (ES) to the saphenous nerve on the microcirculation of the gracilis muscle were assessed through the measurement of two different hemodynamic parameters: (a). the muscle blood flow (MBF) using a laser Doppler flowmeter; and (b). the changes in diameter of the muscle arterioles observed directly using an intravital microscope system. Ipsilateral ES (5 V, 20 Hz, for 30 s) produced increases in MBF and mean arterial pressure (47+/-10% and 18+/-5%) over the baseline, while no significant changes in MBF were observed in the contralateral muscle...
November 22, 2002: Neuroscience Letters
https://www.readbyqxmd.com/read/11895537/a-laser-doppler-study-of-gingival-blood-flow-variations-following-periosteal-stimulation
#15
COMPARATIVE STUDY
Pascal Ambrosini, Sabine Cherene, Neal Miller, Michel Weissenbach, Jacques Penaud
OBJECTIVES: Evaluation of the modifications occurring in human gingival blood flow following periosteal stimulation. MATERIAL AND METHODS: Laser Doppler was used to measure the gingival blood flow (GBF). The reproducibility of the technique was validated by comparing measures made at intervals of 1 week. Sensitivity was verified by recording GBF before and after injection of an anesthetic containing a vasoconstrictor. Finally, 12 patients were subjected to GBF measurements before and 8 days after periosteal stimulation prior to gingival grafting...
February 2002: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/11554808/blood-pressure-changes-induced-by-arterial-blood-withdrawal-influence-bold-signal-in-anesthesized-rats-at-7-tesla-implications-for-pharmacologic-mri
#16
R Kalisch, G K Elbel, C Gössl, M Czisch, D P Auer
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-dependent (BOLD) contrast is now increasingly applied for measuring drug effects on brain activity. A possible confound in pharmacologic fMRI (phMRI) is that the BOLD signal may be sensitive to systemic cardiovascular or respiratory parameters, which can themselves be modulated by a drug. To assess whether abrupt changes in arterial blood pressure (BP) as may be observed in phMRI experiments influence the BOLD signal, a hemorrhage model was studied in anesthesized rats at 7 T using spin-echo EPI...
October 2001: NeuroImage
https://www.readbyqxmd.com/read/11447325/the-mc4-receptor-mediates-alpha-msh-induced-release-of-nucleus-accumbens-dopamine
#17
J Lindblom, B Opmane, F Mutulis, I Mutule, R Petrovska, V Klusa, L Bergström, J E Wikberg
Strong evidence suggests a functional link between the melanocortin and dopamine systems. alpha-Melanocyte stimulating hormone (alpha-MSH) induced grooming behaviour, which can be blocked by dopamine receptor antagonists, is associated with increased dopaminergic transmission in the striatal regions. Whether this effect is mediated specifically by melanocortin (MC) receptors has not previously been established. Using in vivo microdialysis on anesthesized rats we have shown that alpha- MSH administered into the ventral tegmental area induced a significant increase in dopamine and DOPAC levels in the nucleus accumbens...
July 20, 2001: Neuroreport
https://www.readbyqxmd.com/read/10800360/-systematic-recording-of-perioperative-events-associated-with-anesthesia-as-quality-indicator-in-ambulatory-anesthesia
#18
R García-Aguado, M Vivó Benlloch, M J Arcusa Mon, C Peiró Alós, C Zaragoza Fernández, S Castaño Conesa, F Grau Real
OBJECTIVES: To analyze the quality of several anesthetic techniques used for major outpatient surgery in our hospital, by quantifying for each the relative risk (RR) of adverse events during anesthesia and in the postoperative period. PATIENTS AND METHODS: One thousand seventeen patients who underwent surgery between 18 May 1998 and 23 October 1998 were studied retrospectively. RESULTS: The mean age of the patients was 52.27 +/- 24.65 yr; 44...
March 2000: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/10187004/medical-relief-mission-to-bosnia-hercegovina-a-case-report
#19
J R Tryon
World attention has been focused on Bosnia/Hercegovina, where war erupted in 1992. The regional hospital of Mostar, an industrial city with a population of 100,000, operated with chronic shortages of medical supplies including general anesthetic agents. In February 1992, just prior to the referendum for independence in that republic, a shipment of medical supplies with anesthesics, food, and clothing was delivered safely to Ljubuski, a village near Mostar, for Mostar hospital and surrounding clinics by a small, private organization from Birmingham, Alabama...
April 1997: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/9028797/intratracheal-instillation-versus-intratracheal-inhalation-of-tracer-particles-for-measuring-lung-clearance-function
#20
G Oberdörster, C Cox, R Gelein
Effective elimination of particles deposited in the respiratory tract is an important defense function to protect the organism from potentially adverse effects of inhaled particles. Delivery of radioactively labeled tracer particles and subsequent measurement in vivo of their retention in different regions of the respiratory tract provides an adequate method for characterizing this defensive function. However, the delivery of such tracer particles by inhalation may result in some external contamination of the animals and requires specific protective measures while working with radioactive aerosols...
January 1997: Experimental Lung Research
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