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Cervical HNP

Mimi Ghosh, Jason Daniels, Maria Pyra, Monika Juzumaite, Mariel Jais, Kerry Murphy, Tonya N Taylor, Seble Kassaye, Lorie Benning, Mardge Cohen, Kathleen Weber
Sexual violence is associated with increased risk of HIV acquisition/transmission in women. Forced sex can result in physical trauma to the reproductive tract as well as severe psychological distress. However, immuno-biological mechanisms linking sexual violence and HIV susceptibility are incompletely understood. Using the Women's Interagency HIV Study repository, a total of 77 women were selected to form 4 groups, stratified by HIV serostatus, in the following categories: 1) no sexual abuse history and low depressive symptom score (below clinically significant cut-off, scores <16) (Control); 2) no sexual abuse history but high depressive symptom score, ≥16 (Depression); 3) chronic sexual abuse exposure and low depressive symptom score (Abuse); 4) chronic sexual abuse exposure and high depressive symptom score (Abuse+Depression)...
2018: PloS One
Ridha Dharmajaya, Dina Keumala Sari, Ratna Akbari Ganie
BACKGROUND: Herniated Nucleus Pulposus (HNP) is the prolapse of the intervertebral disk through a tear in the annulus fibrosus. This causes nerve root compression with clinical pain manifestation and affects the quality of sleep. AIM: The aim of this study was find out the comparison in the quality of sleep between before (pre) and after (post) surgery cervical HNP patients. METHODS: This study was a retrospective cohort study. Ninety patients were asked to complete the Pittsburgh Sleep Quality Index (PSQI) questionnaire...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
Sung Hoon Kim, Sang-Heon Lee, Nack Hwan Kim, Min Hyun Kim, Hyeun Jun Park, Yong Jin Jung, Hyun-Joon Yoo, Won Jun Meng, Victoria Kim
OBJECTIVE: To evaluate the clinical efficacy and safety following percutaneous disc decompression, using navigable disc decompression device for cervical herniated nucleus pulposus (HNP). METHODS: Twenty subjects diagnosed with cervical HNP and refractory to conservative management were enrolled for the study. The herniated discs were decompressed under fluoroscopic guidance, using radiofrequency ablation device with navigable wand. The sagittal and axial plain magnetic resonance images of the clinically significant herniated disc, decided the space between the herniated base and outline as the target area for ablation...
February 2017: Annals of Rehabilitation Medicine
Yinglin Liu, Yukun Liu, Chuying Du, Rui Zhang, Ziya Feng, Jianping Zhang
OBJECTIVE: To determine the value of measuring amniotic fluid inflammatory biomarkers for diagnosis of subclinical chorioamnionitis. METHODS: A prospective study was conducted among pregnant women with cervical dilation, preterm premature rupture of membranes, threatened late abortion, or threatened premature labor who attended a tertiary care hospital in Guangzhou, China, between June 1, 2012, and January 31, 2014. Participants were divided into two groups according to the presence or absence of subclinical chorioamnionitis...
August 2016: International Journal of Gynaecology and Obstetrics
Tae Wook Nam, Hong Seok Lee, Tae Sik Goh, Jung Sub Lee
STUDY DESIGN: Retrospective study. OBJECTIVE: To identify the significant risk factors for motor weakness caused by cervical disk herniation and for delayed recovery after surgery. SUMMARY OF BACKGROUND DATA: There were a few clinical trials for detecting the significant risk factors for motor weakness after anterior cervical surgery. MATERIALS AND METHODS: We retrospectively examined 72 patients with degenerative disk disease of the cervical spine who were treated with single-level anterior cervical discectomy and fusion...
August 2015: Journal of Spinal Disorders & Techniques
In-Soo Oh, Dong-Whan Suh, Sung-Ryeoll Park, Kee-Yong Ha
BACKGROUND: Herniation of nuclear or disc material along with, inflammatory chemokines such as prostaglandin E2, interleukin-6, matrix metalloproteinase and nitric oxide has definite correlation, possibly they are over produced. CX3CL1 and its receptor (CX3CR1) are part of chemokine system involved in leukocyte recruitment and adhesion in chronic inflammatory disease, but its role in spinal herniated nucleus pulposus (HNP) is unknown. We evaluated the expression of CX3CL1 and CX3CR1 in patients with disc herniation to clarify the role of CX3CL1 and CX3CR1 in the disc degeneration and to compare between cervical and lumbar HNP...
March 2015: Indian Journal of Orthopaedics
Seok-Hee Kim, Da-Jung Jung, Yoo-Min Choi, Jong-Uk Kim, Tae-Han Yook
OBJECTIVES: The purpose of this study is to analyze trends in domestic studies on pharmacopuncture therapy for treating cervical disease. METHODS: This study was carried out on original copies and abstracts of theses listed in databases or published until July 2014. The search was made on the Oriental medicine Advanced Searching Integrated System (OASIS) the National Digital Science Library (NDSL), and the Korean traditional knowledge portal. Search words were 'pain on cervical spine', 'cervical pain', 'ruptured cervical disk', 'cervical disc disorder', 'stiffness of the neck', 'cervical disk', 'whiplash injury', 'cervicalgia', 'posterior cervical pain', 'neck disability', 'Herniated Nucleus Pulposus (HNP)', and 'Herniated Intervertebral Disc (HIVD)'...
December 2014: Journal of Pharmacopuncture
Gregory L Cvetanovich, Andrew R Hsu, Rachel M Frank, Howard S An, Gunnar B Andersson
The majority of patients with symptomatic herniated discs can be successfully and conservatively managed and can achieve clinical improvement without surgical intervention. Resorption of the herniated nucleus pulposus (HNP) is 1 conservative mechanism for clinical improvement. We present the case of a 76-year-old healthy man with acute cervical radicular right arm pain and positive Spurling test. Magnetic resonance imaging (MRI) showed a large disc extrusion behind the C6 vertebral body, causing severe central canal stenosis and right-greater-than-left foraminal stenosis...
July 2014: American Journal of Orthopedics
F Gioia, D Gorga, W Nagler
The magnetic resonance imaging (MRI) reports and pain questionnaires of 100 patients with complaints of lower back or neck pain were reviewed. Prior to physician examination, each patient had completed a questionnaire which included pain drawings and a rating on a pain scale. The information given on the drawings and questionnaires was compared to the MRI reports. The levels of agreement between them were analyzed. The results show that the pain questionnaire with drawing is a useful tool in the evaluation of patients when the diagnoses of herniated nucleus pulposis (HNP) or spinal stenosis are in question...
January 1, 1997: Journal of Back and Musculoskeletal Rehabilitation
Frank Lee, David E Jamison, Robert W Hurley, Steven P Cohen
As our population ages and the rate of spine surgery continues to rise, the use epidural lysis of adhesions (LOA) has emerged as a popular treatment to treat spinal stenosis and failed back surgery syndrome. There is moderate evidence that percutaneous LOA is more effective than conventional ESI for both failed back surgery syndrome, spinal stenosis, and lumbar radiculopathy. For cervical HNP, cervical stenosis and mechanical pain not associated with nerve root involvement, the evidence is anecdotal. The benefits of LOA stem from a combination of factors to include the high volumes administered and the use of hypertonic saline...
January 2014: Korean Journal of Pain
A E Elgersma, I D Wijnberg, J Sleutjens, J H van der Kolk, P R van Weeren, W Back
REASONS FOR PERFORMING STUDY: Head and neck positions (HNP) in sport horses are under debate in the equine community, as they could interfere with equine welfare. HNPs have not been quantified objectively and no information is available on their head and neck loading. OBJECTIVES: To quantify in vivo HNPs in sport horses and develop o a model to estimate loading on the cervical vertebrae in these positions. METHODS: Videos were taken of 7 Warmbloods at walk on a straight line in 5 positions, representing all HNPs during Warmblood training and competition...
November 2010: Equine Veterinary Journal. Supplement
Smith L Johnston, Mark R Campbell, Rick Scheuring, Alan H Feiveson
INTRODUCTION: Astronauts have complained of back pain occurring during spaceflight, presumably due to the elongation of the spine from the lack of gravity. Herniated nucleus pulposus (HNP) is known to occur in aviators exposed to high Gz and has been diagnosed in several astronauts in the immediate post-spaceflight period. It is unknown whether astronauts exposed to microgravity are at added risk for developing HNP in the post-spaceflight period due to possible in-flight intervertebral disc changes...
June 2010: Aviation, Space, and Environmental Medicine
Barbara E Wiechuła, Daniela A Friedek, Alicja M Ekiel, Małgorzata K Romanik, Gayane Martirosian
Development of female genito-urinary infections depends on many factors, such as immune system activity, virulence of microorganism and production of factors inhibiting the growth of microorganisms. Taking into account the possibility of relapses or severe complications, it is very important to appropriately diagnose and treat infections. Because of recently observed increase of microbial resistance to antibiotics, researchers are looking for alternatives. In our study we evaluated and compared the concentration of human neutrophil peptides (HNP 1-3) in cervico-vaginal lavages (CVL), obtained from women with vaginitis/cervicitis...
2007: Polish Journal of Microbiology
P-Y Marcy, E Chamorey, N Amoretti, K Benezery, R J Bensadoun, A Bozec, G Poissonnet, O Dassonville, M Rame, A Italiano, F Peyrade, F Brenac, J C Gallard
AIM: To compare technical feasibility and complications of radiologically arm port device implantation using arm venography exclusively (API-Group B) with chest port placement using cephalic vein cutdown (CVC-Group A), in advanced consecutive head and neck cancer patients (HNP). METHODS: Port device placement was attempted in 225 consecutive HNP. Decision for inclusion in Group A or B was made first by the availability of the surgeon/radiologist to perform the procedure, second by contraindications of each technique...
November 2008: European Journal of Surgical Oncology
Pascale Hubert, Ludivine Herman, Catherine Maillard, Jean-Hubert Caberg, Arjen Nikkels, Gerald Pierard, Jean-Marie Foidart, Agnès Noel, Jacques Boniver, Philippe Delvenne
In addition to their direct antimicrobial activity, defensins might also influence adaptive immunity by attracting immature dendritic cells (DC). As these cells have been shown to be deficient in uterine cervix carcinogenesis, we evaluated the ability of alpha-defensin (HNP-2, human neutrophil defensin 2) and beta-defensin (HbetaD2, human beta defensin 2) to stimulate their migration in human papillomavirus (HPV)-associated (pre)cancers. We first observed, using RT-PCR and immunohistology, that HbetaD2 is absent in HPV-transformed keratinocytes and that it is weakly expressed in cervical (pre)neoplastic lesions in comparison with normal keratinocytes...
September 2007: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Ehsan Hazrati, Benjamin Galen, Wuyuan Lu, Wei Wang, Yan Ouyang, Marla J Keller, Robert I Lehrer, Betsy C Herold
This study examined the ability of nine human defensins (HD) to protect against herpes simplex virus infection. Noncytotoxic concentrations of all six alpha-defensins (HNP1-4, HD5, and HD6) and human beta-defensin (hBD) 3 inhibited HSV infection. Two other beta-defensins, hBD1 and 2, lacked this protective activity. Synchronized assays revealed that HNP-4, HD6, and hBD3 acted primarily by preventing binding and entry, whereas HNP1-3 and HD5 also inhibited postentry events. Even when added several hours after entry, substantial reduction in viral gene expression ensued...
December 15, 2006: Journal of Immunology: Official Journal of the American Association of Immunologists
Kyung-Hoon Kim, Sung-Hwan Choi, Tae-Kyun Kim, Sang-Wook Shin, Cheul-Hong Kim, Jeung-Il Kim
The effects from cervical facet joint injections in those patients who have been complaining cervical zygapophyseal joint pain were compared. The patients were diagnosed originally as myofascial pain syndrome (MPS), cervical herniated nucleus pulposus (HNP), and whiplash-associated disorders (WAD). Patients with the zygapophyseal joints pain of C5-6 and C6-7 were classified by their pain origin as MPS, HNP, and WAD. All patients had been undergone cervical zygapophyseal joints injections with the mixture of lidocaine and triamcinolone unilaterally or bilaterally through the posterior approach under C-arm imaging guide...
August 2005: Journal of Korean Medical Science
Ming Li, Xiao-ling Pan, Li-li Wang, Yun Feng, Ning Huang, Qi Wu, Xuan Li, Bo-yao Wang
OBJECTIVE: To isolate and purify antibacterial polypeptides from human cervical mucus. METHODS: Human cervical mucus was collected from human healthy subjects and acid-soluble extract was obtained by solving the mucus with 5% acetic acid in the presence of protease inhibitors. The antibacterial components were identified by Agar radial diffusion assay and gel overlay technique. For further purification, Preparative acid-urea gel electrophoresis and Reverse Phase HPLC were performed...
April 27, 2005: Zhonghua Yi Xue za Zhi [Chinese medical journal]
C C Boedeker, G J Ridder, J Schipper
Paragangliomas of the head and neck (HNP) represent rare tumors of neural crest origin. They are highly vascular neoplasms that are benign in the majority of cases. The site of origin defines the name given those tumors. In the head and neck, they most commonly occur at the carotid bifurcation, where they are referred to as carotid body tumors (CBT). Other common sites of origin are the jugular bulb (jugular paraganglioma; JP), the tympanic plexus on the promontory (tympanic paraganglioma; TP) and the vagal nerve (vagal paraganglioma; VP)...
2005: Familial Cancer
Michael Schneider, Steven Santolin, Patrick Farrell
OBJECTIVES: The purpose of this study is to present 2 clinical case studies in which large herniated disks were not detected on magnetic resonance imaging (MRI), leading to false negative results, and discuss some issues regarding potential shortcomings of MRI. CLINICAL FEATURES: Cases of cervical and lumbar herniated nucleus pulposus (HNP) are presented. Each patient had severe pain and neurological deficit. The patients had positive physical examination findings suggestive of HNP despite the negative MRI scans...
May 2005: Journal of Manipulative and Physiological Therapeutics
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