keyword
MENU ▼
Read by QxMD icon Read
search

Healthy aging

keyword
https://www.readbyqxmd.com/read/29346794/clinicoepidemiologic-features-of-chronic-urticaria-in-patients-with-versus-without-subclinical-helicobacter-pylori-infection-a-cross-sectional-study-of-150-patients
#1
Sakshi Kohli, Vikram K Mahajan, Baldev S Rana, Karaninder S Mehta, Rashmi Kaul Raina, Pushpinder S Chauhan, Vikas Sharma, Ritu Rawat
BACKGROUND: The Helicobacter pylori infection is linked to chronic urticaria in nearly 60% of patients. We studied clinicoepidemiologic features in patients with chronic urticaria with and without H. pylori infection. METHODS: Endoscopic antral biopsy for the rapid urease test (RUT) and histopathology, and serum IgG ELISA for H. pylori infection were performed in 150 patients (male:female ratio 1:2.4) of chronic urticaria aged 18-68 years. Clinicoepidemiologic features including age, gender, age of onset and duration, frequency and distribution of wheals, urticaria severity score, and systemic symptoms were analyzed in patients with and without H...
January 19, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29346518/determinants-of-health-trajectories-in-england-and-the-us-an-approach-to-identify-different-patterns-of-healthy-aging
#2
Javier de la Fuente, Francisco Félix Caballero, Albert Sánchez-Niubó, Demosthenes B Panagiotakos, Matthew A Prina, Holger Arndt, Josep Maria Haro, Somnath Chatterji, José Luis Ayuso-Mateos
Background: Aging is a multidimensional process with a remarkable inter-individual variability. This study is focused on identifying groups of population with similar aging patterns, and to define the health trajectories of these groups. Socio-demographic and health determinants of these trajectories are also identified. Methods: Data from the English Longitudinal Study of Aging (ELSA) and the Health and Retirement Study (HRS) were used. A set of self-reported health items and measured tests were used to generate a latent health metric by means of a Bayesian multilevel IRT model, assessing the ability of the metric to predict mortality...
January 16, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29346499/repeatability-and-agreement-of-visual-acuity-using-the-etdrs-number-chart-landolt-c-chart-or-etdrs-alphabet-chart-in-eyes-with-or-without-sight-threatening-diseases
#3
Voraporn Chaikitmongkol, Onnisa Nanegrungsunk, Direk Patikulsila, Paisan Ruamviboonsuk, Neil M Bressler
Importance: The Early Treatment Diabetic Retinopathy Study (ETDRS) alphabet chart is not feasible for measuring best-corrected visual acuity (BCVA) for individuals who are unfamiliar with the Roman alphabet. The ETDRS Landolt C chart is an alternative, but it may not reflect true BCVA among those with confusion between left and right. The ETDRS number chart might overcome these limitations, but little is known regarding its reliability. Objective: To evaluate repeatability and agreement of BCVA using the ETDRS number chart or Landolt C chart compared with ETDRS alphabet charts in healthy and diseased eyes...
January 18, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29346407/relaxin-reverses-inflammatory-and-immune-signals-in-aged-hearts
#4
Brian Martin, Beth Ann Gabris-Weber, Rajiv Reddy, Guillermo Romero, Ansuman Chattopadhyay, Guy Salama
BACKGROUND: 'Healthy' aging drives structural and functional changes in the heart including maladaptive electrical remodeling, fibrosis and inflammation, which lower the threshold for cardiovascular diseases such as heart failure (HF) and atrial fibrillation (AF). Despite mixed results in recent clinical trials, Relaxin-therapy for 2-days could reduce mortality by 37% at 180-days post-treatment, in patients with acute decompensated HF. Relaxin's short life-span (hours) but long-lasting protective actions led us to test the hypothesis that relaxin acts at a genomic level to reverse maladaptive remodeling in aging and HF...
2018: PloS One
https://www.readbyqxmd.com/read/29346396/serum-mirna-levels-are-related-to-glucose-homeostasis-and-islet-autoantibodies-in-children-with-high-risk-for-type-1-diabetes
#5
Linda Åkerman, Rosaura Casas, Johnny Ludvigsson, Beatriz Tavira, Camilla Skoglund
Micro RNAs (miRNAs) are promising disease biomarkers due to their high stability. Their expression in serum is altered in type 1 diabetes, but whether deviations exist in individuals with high risk for type 1 diabetes remains unexplored. We therefore assessed serum miRNAs in high-risk individuals (n = 21) positive for multiple islet autoantibodies, age-matched healthy children (n = 17) and recent-onset type 1 diabetes patients (n = 8), using Serum/Plasma Focus microRNA PCR Panels from Exiqon. The miRNA levels in the high-risk group were similar to healthy controls, and no specific miRNA profile was identified for the high-risk group...
2018: PloS One
https://www.readbyqxmd.com/read/29346338/current-cigarette-smoking-among-adults-united-states-2016
#6
Ahmed Jamal, Elyse Phillips, Andrea S Gentzke, David M Homa, Stephen D Babb, Brian A King, Linda J Neff
The U.S. Surgeon General has concluded that the burden of death and disease from tobacco use in the United States is overwhelmingly caused by cigarettes and other combusted tobacco products (1). Cigarettes are the most commonly used tobacco product among U.S. adults, and about 480,000 U.S. deaths per year are caused by cigarette smoking and secondhand smoke exposure (1). To assess progress toward the Healthy People 2020 target of reducing the proportion of U.S. adults aged ≥18 years who smoke cigarettes to ≤12...
January 19, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29346167/new-reference-values-for-cardiopulmonary-exercise-testing-in-children
#7
Joel Blanchard, Samuel Blais, Philippe Chetaille, Michele Bisson, François P Counil, Thelma H Girard, Jade Berbari, Pierre Boulay, Frederic Dallaire
INTRODUCTION: Cardiopulmonary exercise testing (CPET) is an essential tool to assess cardiorespiratory fitness (CRF) in children. There is a paucity of adequate pediatric reference values that are independent of body size and pubertal stage. The purpose of this study is to provide Z score equations for several maximal and sub-maximal CRF parameters derived from a prospectively recruited sample of healthy children. METHODS: In this cross-sectional multicenter study, we prospectively recruited 228 healthy children aged 12 to 17 years old in local schools...
January 17, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29346081/reported-balance-confidence-and-movement-reinvestment-of-younger-knee-replacement-patients-are-more-like-younger-healthy-individuals-than-older-patients
#8
Brian D Street, Allan Adkin, William Gage
This study focused on differences between the rapidly growing younger (<65 years old) and older (>65 years old) total knee replacement (TKR) patients for measures of balance confidence, movement reinvestment, and functional mobility. Fifty-nine participants, including twenty-nine primary unilateral TKR patients (six months post-TKR) formed the four experimental groups: 1) Younger TKR Patient (YP), 2) Younger Control (YC), 3) Older TKR Patient (OP), and 4) Older Control (OC). The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Oxford Knee Score (OKS), Activities-specific Balance Confidence scale (ABC), the Movement-Specific Reinvestment Scale (MSRS), and the Timed Up and Go (TUG) test were measured...
January 11, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29345733/putative-mechanisms-of-cognitive-decline-with-implications-for-clinical-research-and-practice
#9
Tadeu Oliveira, Angela Starkweather, Divya Ramesh, Joseph Fetta, Debra Lynch Kelly, Debra E Lyon, Lana Sargent
Multiple intrinsic and extrinsic mechanisms contribute to vulnerability of cognitive decline and nurses play a significant role in assisting individuals and families to use strategies for healthy cognitive aging. The objective of this narrative review is to provide a synthesis of the intrinsic and extrinsic mechanisms of cognitive decline and conditions that are associated with cognitive decline. Well-established intrinsic mechanisms of cognitive decline include aging, apolipoprotein E (APOE) ε4 carrier status, SORL1 mutations, neuroinflammation, mitochondrial dysfunction, amyloid deposition, and demyelination...
January 18, 2018: Nursing Forum
https://www.readbyqxmd.com/read/29345602/the-mental-health-of-adolescents-and-pre-adolescents-living-with-inherited-arrhythmia-syndromes-a-systematic-review-of-the-literature
#10
Patricia E Longmuir, Margaret Sampson, Jennifer Ham, Makenzie Weekes, Bhavika J Patel, Robert M Gow
Potentially fatal arrhythmias add to the mental health challenges of adolescence. This systematic review sought to summarise current knowledge regarding the mental health of adolescents and pre-adolescents diagnosed with inherited arrhythmia syndromes. Searches combining psychological problems with inherited cardiac arrhythmia diagnoses identified 16 studies with paediatric (<18 years) inherited arrhythmia patients. All studies were cross-sectional; 8/16 required an implantable cardioverter defibrillator...
January 18, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29345526/differential-gait-patterns-by-falls-history-and-knee-pain-status-in-healthy-older-adults-results-from-the-baltimore-longitudinal-study-of-aging
#11
Seung-Uk Ko, Gerald J Jerome, Eleanor M Simonsick, Stephanie Studenski, Luigi Ferrucci
Consideration of knee pain can be crucial for identifying fall-related gait patterns. Gait parameters while walking at usual speed were examined in persons with different falls and knee pain status. Study participants were 439 adults aged 60 to 92 years. Persons with a falls history had a wider stride width (p = 0.036) and longer double support time (p = 0.034) than non-fallers. In the absence of knee pain, fallers had longer double support time than non-fallers (p = 0.012), but no differences in double support time by fall history was observed in participants with knee pain...
January 18, 2018: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/29345408/the-effect-of-eradication-of-helicobacter-pylori-on-gastric-cancer-prevention-in-healthy-asymptomatic-populations
#12
Suh Eun Bae, Kee Don Choi, Jaewon Choe, Seon Ok Kim, Hee Kyong Na, Ji Young Choi, Ji Yong Ahn, Kee Wook Jung, JeongHoon Lee, Do Hoon Kim, Hye-Sook Chang, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
BACKGROUND: Although many epidemiologic studies have evaluated the effect of Helicobacter pylori eradication on gastric cancer, the effect is still uncertain in general populations. We evaluated whether H. pylori eradication would affect the incidence of gastric cancer in healthy asymptomatic populations. MATERIALS AND METHODS: We performed a retrospective cohort study in 38 984 asymptomatic individuals, who underwent health screening examinations more than twice between 2005 and 2016...
January 18, 2018: Helicobacter
https://www.readbyqxmd.com/read/29345201/clinical-validation-of-nuclear-factor-kappa-b-expression-in-invasive-breast-cancer
#13
Anil Kumar Agrawal, Ewa Pielka, Artur Lipinski, Michal Jelen, Wojciech Kielan, Siddarth Agrawal
Breast cancer is the most commonly diagnosed cancer in Polish women. The expression of transcription nuclear factor kappa B, a key inducer of inflammatory response promoting carcinogenesis and cancer progression in breast cancer, is not well-established. We assessed the nuclear factor kappa B expression in a total of 119 invasive breast carcinomas and 25 healthy control samples and correlated this expression pattern with several clinical and pathologic parameters including histologic type and grade, tumor size, lymph node status, estrogen receptor status, and progesterone receptor status...
January 2018: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/29345171/comparison-of-bioelectrical-impedance-analysis-and-dual-energy-x-ray-absorptiometry-for-estimating-bone-mineral-content
#14
Tori M Stone, Jonathan E Wingo, Brett S Nickerson, Michael R Esco
The purpose of this study was to validate single-frequency hand-to-foot bioelectrical impedance analysis (HFBIA) for estimating bone mineral content (BMC) using dual energy X-ray absorptiometry (DXA) as the criterion measure in healthy, men and women aged 18-40 y. A total of 80 men and women participated. Bone mineral content was estimated on the same day using HFBIA and DXA. HFBIA device provided higher mean BMC values in men and the entire sample, but not in women. A smaller standard error of estimate was observed in women (0...
January 18, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29345041/serum-amyloid-a-procalcitonin-highly-sensitive-c-reactive-protein-and-tumor-necrosis-factor-alpha-levels-and-acute-inflammatory-response-in-patients-with-hemolysis-elevated-liver-enzymes-low-platelet-count-hellp-and-eclampsia
#15
Kazım Uckan, Hanım Guler Sahin
AIM: The aim of this study was to determine the relationship between serum amyloid A (SAA), procalcitonin (ProC), highly sensitive C reactive protein (hsCRP) and tumor necrosis factor (TNF) alpha activity in patients with pre-eclampsia, eclampsia and hemolysis, elevated liver enzymes, low platelet count (HELLP), and the pathogenesis and severity of the disease. METHOD: Ninety patients at ≥ 32 gestational weeks, according to the last date of menstruation and ultra-sonographic measurements, diagnosed with pre-eclampsia (30 patients), eclampsia (30 patients) or HELLP syndrome (30 patients) were included in the study...
January 18, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29344986/evaluation-of-bowel-function-in-healthy-children-untreated-constipation-is-common
#16
Helena Lindgren, Malin Carvalho Nejstgaard, Martin Salö, Pernilla Stenström
AIM: We evaluated bowel function in healthy children with regard to gender and age. METHODS: The study was carried out in 2016 at a tertiary children's hospital. Healthy children aged 3.5-15 years old who were admitted to the hospital, siblings to patients, or offspring of staff members were included. Validated self-report questionnaires, and internally developed questions regarding obstructive outlet- and gas-related symptoms were used. RESULTS: A total of 310 participants (50% girls) were included, which corresponded to a 94% answer frequency...
January 18, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29344967/predictive-neuromechanical-simulations-indicate-why-walking-performance-declines-with-aging
#17
Seungmoon Song, Hartmut Geyer
Healthy elderly people walk slower and energetically less efficiently than young adults. This decline in walking performance lowers the quality of life for a growing aging population, and understanding its physiological origin is critical for devising interventions that can delay or revert it. However, the origin of the decline in walking performance remains unknown, as aging produces a range of physiological changes whose individual effects on gait are difficult to separate in experiments with human subjects...
January 17, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29344750/physical-activity-and-consumption-patterns-of-reproductive-aged-women-by-bmi-category
#18
Jennifer K Bello, Debra B Stulberg, Ying Zhou, Chi Wang
Objectives Obesity before and during pregnancy is associated with adverse effects for mother and child, but little is known about physical activity and consumption patterns among reproductive-aged women. The goal of this study is to identify behaviors of nonpregnant reproductive-aged women associated with normal weight, overweight, and obesity. Methods Data from the nationally representative National Eating Trends survey (2003-2011) were analyzed, comparing number of days of exercise in a 1-week period and consumption of fruits/vegetables, sugar sweetened beverages (SSB), and concentrated sweets by BMI...
January 17, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29344581/glycophorin-c-sialylation-regulates-lu-bcam-adhesive-capacity-during-erythrocyte-aging
#19
T R L Klei, D Z de Back, P J Asif, P J J H Verkuijlen, M Veldthuis, P C Ligthart, J Berghuis, E Clifford, B M Beuger, T K van den Berg, R van Zwieten, W El Nemer, R van Bruggen
Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises. On healthy erythrocytes however, its function is unclear. Here we report that Lu/BCAM is activated during erythrocyte aging. We show that Lu/BCAM-mediated binding to laminin-α5 is restricted by interacting, in cis, with glycophorin-C-derived sialic acid residues...
January 9, 2018: Blood Advances
https://www.readbyqxmd.com/read/29344423/age-related-gray-and-white-matter-changes-in-normal-adult-brains
#20
Farnaz Farokhian, Chunlan Yang, Iman Beheshti, Hiroshi Matsuda, Shuicai Wu
Normal aging is associated with both structural changes in many brain regions and functional declines in several cognitive domains with advancing age. Advanced neuroimaging techniques enable explorative analyses of structural alterations that can be used as assessments of such age-related changes. Here we used voxel-based morphometry (VBM) to investigate regional and global brain volume differences among four groups of healthy adults from the IXI Dataset: older females (OF, mean age 68.35 yrs; n=69), older males (OM, 68...
December 2017: Aging and Disease
keyword
keyword
7338
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"