Read by QxMD icon Read

Peritoneal tuberculosis

Shuwei Zheng, Humaira Shafi
Paradoxical reactions during tuberculosis (TB) treatment are well-described in the HIV seropositive population but less so in the HIV seronegative group. Abdominal TB rarely presents as spontaneous perforation; cases occurring during anti-TB therapy are even rarer. We describe the clinical progress of a case of an HIV-negative patient who developed acute peritonitis while on anti-TB treatment for peritoneal TB through a series of clinical, radiological and histological images. Visceral perforation can occur as a complication of TB treatment...
January 2018: International Journal of Mycobacteriology
A Kienlen, C Fernandez, Z Henni-Laleg, M Andre, V Gazaille, N Coolen-Allou
Thoracic endometriosis is a rare entity characterized by presence of endometrial tissue in pleura, lung parenchyma or airways. Most frequent manifestations are catamenial pneumothorax, hemothorax, hemoptysis and pulmonary nodules. We report here a rare case of a woman with thoracic endometriosis who developed iterative pneumothorax and pneumopericardium on bilateral bullous pulmonary dystrophy. She was a 37-year-old woman without any tobacco exposure and with previous history of pleural tuberculosis treated 5 years earlier...
March 1, 2018: Revue de Pneumologie Clinique
Mihai Mareș, Valentina Ruxandra Moroti-Constantinescu, David W Denning
OBJECTIVE: To estimate for the first time the burden of fungal infections in Romania. METHODS: Data derived from the World Health Organization (WHO), National Institute of Statistics, Romanian public health agencies and non-profit health organizations, and published annual reports on local epidemiology were used in the present study. When no data were available, specific at-risk populations were used to calculate frequencies of serious fungal diseases, using previously published epidemiological parameters...
March 1, 2018: Journal of Fungi (Basel, Switzerland)
Ciara Ordoñez, Hannah P Savage, Musharaf Tarajia, René Rivera, Cheyenne Weeks-Galindo, Dilcia Sambrano, Lee Riley, Patricia L Fernandez, Nicole Baumgarth, Amador Goodridge
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. The cellular immune response to Mycobacteria has been characterized extensively, but the antibody response remains underexplored. The present study aimed to examine whether host or bacterial phospholipids induce secretion of IgM, and specifically anti-phospholipid IgM, antibodies by B cells and to identify the responsible B cell subset. Here we show that peritoneal B cells responded to lipid antigens by secreting IgM antibodies. Specifically, stimulation with Mycobacterium tuberculosis H37Rv total lipids resulted in significant induction of total and anti-phosphatidylcholine IgM...
February 18, 2018: Immunology
Georgi Abraham, Amit Gupta, Kashi Nath Prasad, Anusha Rohit, Anil Kumar Bhalla, Vishwanath Billa, Rajasekhar Chakravati, Tonmoy Das, Thadakanathan Dhinakaran, Arup Ratan Dutta, Padmanabhan Giri, Tarun Jeloka, Sampath Kumar, Ajay Marwaha, Radha Vijay Raghavan, Rajan Ravichandran, Roshan Rohit, Chandra Nath Sarkar, Naorem Sharat Kumar Singh
BACKGROUND: Peritoneal dialysis (PD)-related peritonitis is a major risk factor for drop out of patients on continuous ambulatory PD (CAPD) and automated PD (APD). Factors affecting PD-related peritonitis and centre-specific microbiological data are lacking in India. A multicentric prospective observational study was designed to overcome the gaps in the existing data regarding causative organism and outcome. METHODOLOGY: The present study was a prospective, uncontrolled, open-label; observational study conducted in 21 centres representing all the four geographical regions (North, South, East and West) of India between April 2010 and December 2011...
October 2017: Indian Journal of Medical Microbiology
Dilip Sharma, Sudhamshu Kc, Bikash Jaisi
BACKGROUND: Studies have shown that patients with liver cirrhosis are more susceptible to tuberculosis because of immune dysfunction; however there are only limited data. We carried out this study to know the prevalence and clinical characteristics of tuberculosis in patients with liver cirrhosis. METHODS: In this retrospective study, medical files of 200 consecutive patients admitted with diagnosis of liver cirrhosis in the medical ward of liver unit, Bir Hospital from January 2011 to December 2014 were evaluated for the presence of TB and clinical characteristics of these patients were analyzed...
January 1, 2018: Journal of Nepal Health Research Council
Vishal Sharma, Harshal S Mandavdhare, Sandeep Lamoria, Harjeet Singh, Amit Kumar
BACKGROUND: Response to treatment is often used as a criterion for the diagnosis of abdominal tuberculosis. AIM: To determine utility of serum C reactive protein (CRP) in assessment of response to anti-tubercular therapy (ATT) in abdominal tuberculosis (ATB). METHODS: We retrospectively analysed the database of patients with suspected ATB (intestinal and/or peritoneal). Response to ATT was assessed using subjective and objective (ulcer healing or ascites resolution) parameters...
December 19, 2017: Digestive and Liver Disease
Gurhan Sisman, Lara Karaaslan, Nurdan Tözün
Ascites can pose a difficult problem in diagnosis of peritoneal tuberculosis, and diagnostic laparoscopy or laparotomy is eventually required in some patients. Herein, we reported the diagnosis of peritoneal tuberculosis in a patient with ascites by using endosonography (EUS) assisted through the needle biopsy forceps (TTNB). The patient was immediately started on the tuberculosis treatment. This article is protected by copyright. All rights reserved.
December 30, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Beng Kwang Ng, Kembang Aziah Yakob, Wendy Yin Ling Ng, Pei Shan Lim, Rahana Abd Rahman, Abdul Kadir Abdul Karim, Ani Amelia Zainuddin, Zaleha Abdullah Mahdy
Tuberculosis (TB) remained as one of the top 10 causes of death worldwide despite an overall decline in its incidence rate globally. Extrapulmonary TB is uncommon and only accounts for 10-20% of overall TB disease burden. Abdominopelvic TB is the sixth most common location of extrapulmonary TB. The symptoms and signs are often insidious and nonspecific. Diagnosing abdominopelvic TB can be very challenging at times and poses great difficulties to the clinician. Infection with nontuberculous Mycobacterium (NTM) is even rarer especially in an immunocompetent patient...
2017: Case Reports in Medicine
Vishal Sharma, Surinder Singh Rana, Sobur Uddin Ahmed, Sonali Guleria, Ravi Sharma, Rajesh Gupta
The peritoneum is involved in many diseases such as primary malignancy (mesothelioma), infectious disease (tuberculosis), and disseminated malignancy (peritoneal carcinomatosis). The peritoneal disease may manifest as ascites and/or peritoneal masses or nodules. Endoscopic ultrasound (EUS), due to its ability to provide high-resolution images, has revolutionized the imaging and diagnosis of pancreaticobiliary diseases among other gastrointestinal conditions. EUS can not only help in imaging of various lesions close to the gastrointestinal lumen but also aspirate/biopsy them...
November 2017: Endoscopic Ultrasound
M H Nor Fauziah, M Z Faizah, C K Loh
A four-year-old Ibanese boy presented with subacute abdominal distension for two months duration. Ultrasound and computed tomography (CT) scan showed solid liver masses as well as bowel and intraperitoneal lesions. Initial diagnosis of intraperitoneal inflammatory process as in tuberculosis with non-liquefied liver abscess with differential diagnosis of neoplastic process was made. Liver biopsy and peritoneal fluid analysis revealed Burkitt's lymphoma (BL). We aim to highlight the diagnostic challenge of BL in this young age group emphasizing on the ultrasound and CT features of intraabdominal BL...
October 2017: Medical Journal of Malaysia
Qingwen Zhang, Jinxia Sun, Yuli Wang, Weigang He, Lixin Wang, Yuejuan Zheng, Jing Wu, Ying Zhang, Xin Jiang
Tuberculosis (TB) remains a leading killer worldwide among infectious diseases and the effective control of TB is still challenging. Autophagy is an intracellular self-digestion process which has been increasingly recognized as a major host immune defense mechanism against intracellular microorganisms like Mycobacterium tuberculosis (Mtb) and serves as a key negative regulator of inflammation. Clinically, chronic inflammation surrounding Mtb can persist for decades leading to lung injury that can remain even after successful treatment...
2017: Frontiers in Microbiology
Giovanni Sotgiu, Dennis Falzon, Vahur Hollo, Csaba Ködmön, Nicolas Lefebvre, Andrei Dadu, Marieke van der Werf
BACKGROUND: We explored host-related factors associated with the site of tuberculosis (TB) disease using variables routinely collected by the 31 EU/EEA countries for national surveillance. METHODS: Logistic regression models were fitted to case-based surveillance data reported to the European Centre for Disease Prevention and Control for TB cases notified from 2003 to 2014. Missing data on HIV infection and on susceptibility to isoniazid and rifampicin for many patients precluded the inclusion of these variables in the analysis...
2017: PloS One
Wajid Hafeez, S Rajalakshmi, S Sripriya, M Madhu Bashini
Background and Aim Diagnosis of typhoid is challenging when blood cultures fail to isolate Salmonella species. We report our experience with interpreting computed tomography (CT) abdomen findings in a case series of typhoid fever. Methods The case series consisted of patients who had a CT abdomen done as part of their investigations and a final diagnosis of typhoid fever. The CT films were reviewed and findings evaluated for distinctive features. Results During 2011-2017, 11 patients met the inclusion criteria...
January 1, 2017: Tropical Doctor
Lizhen Wang, Shaojie Feng, Subo Wang, Hui Li, Zhongwu Guo, Guofeng Gu
A monophosphoryl lipid A (MPLA) derivative having the 6'-OH group substituted with an NH2 group was synthesized and coupled with the upstream terminal tetrasaccharide of mycobacterial lipoarabinomannan (LAM) via an amide bond to create a novel type of MPLA-based fully synthetic glycoconjugate vaccine. The same tetrasaccharide was also coupled with MPLA at the 1-O-position. Immunological activities of the two synthetic conjugates were evaluated in mice and compared. Both afforded robust overall and IgG antibody responses, but intraperitoneal injection elicited responses significantly stronger than those from subcutaneous injection...
December 1, 2017: Journal of Organic Chemistry
Timo Rath, Raja Atreya, Walter Geißdörfer, Roland Lang, Andreas Nägel, Markus F Neurath
Although generally rising in incidence, intestinal tuberculosis is still rare in western countries and due to unspecific manifestations mainly as ulcerations on endoscopy, diagnosis of intestinal tuberculosis is challenging. Within this report, we describe a case of severe intestinal tuberculosis radiologically and endoscopically masquerading as colorectal cancer with peritoneal carcinomatosis. Our case exemplifies that intestinal tuberculosis needs to be considered as a differential diagnosis in patients at risk and that undelayed and sensitive diagnosis of intestinal tuberculosis is of central importance for avoiding unfavorable disease outcome...
2017: Case Reports in Gastrointestinal Medicine
Alok K Mishra, Shivraj M Yabaji, Rikesh K Dubey, Ekta Dhamija, Kishore K Srivastava
The remarkable ability of Mycobacterium tuberculosis ( Mtb ) to survive inside human macrophages is attributed to the presence of a complex sensory and regulatory network. PrrA is a DNA-binding regulatory protein, belonging to an essential two-component system (TCS), PrrA/B, which is required for early phase intracellular replication of Mtb. Despite its importance, the mechanism of PrrA/B-mediated signaling is not well understood. In the present study, we demonstrate that the binding of PrrA on the promoter DNA and its consequent activation is cumulatively controlled via dual phosphorylation of the protein...
December 6, 2017: Biochemical Journal
Meng Zhu, Ning Zhang, Wei Tao, Zhitao Wang, Shuixiang He
Pancreatic tuberculosis (TB) is an extremely rare form of extrapulmonary tuberculosis even in endemic areas that masquerades as a mass or inflammation because of lack of typical clinical manifestations and radiologic features and therefore usually misdiagnosed as a pancreatic malignancy or pancreatitis. Here we present a 23-year-old young man with pancreatic tuberculosis mimicking pancreatic head carcinoma A man who suffered from upper abdominal pain and nausea for half a month was admitted to our hospital...
2017: Case Reports in Medicine
Ah-Ra Jang, Joo-Hee Choi, Sung Jae Shin, Jong-Hwan Park
Mycobacterium tuberculosis is a highly virulent bacterium that causes tuberculosis. It infects about one third of the world's population. Type I interferons (IFNs) play a detrimental role in host defense against M. tuberculosis infection. Proteins secreted by M. tuberculosis through ESX-1 secretion system contribute to type I IFNs production. However, the precise mechanism by which 6-kDa early secretory antigen target (ESAT6), one of ESX-1-mediated secretory proteins, induces type I IFNs production in host cells is currently unclear...
October 15, 2017: Cytokine
Tulin Cagatay, Zuleyha Bingol, Esen Kıyan, Zeynep Yegin, Gulfer Okumus, Orhan Arseven, Feyza Erkan, Ziya Gulbaran, Mustafa Erelel, Turhan Ece, Penbe Cagatay', Zeki Kılıçaslan
OBJECTIVES: To evaluate the characteristics of patients who developed tuberculosis while receiving tumor necrosis factor-alpha (TNF-α) antagonists and the related factors with tuberculosis. METHODS: Patient's demographics, tuberculin skin test (TST), isoniazid prophylaxis, type of TNF-α antagonist were recorded. TST conversion (>5mm increase) was evaluated for patients who had baseline and 1-year TST. RESULTS: Files of 1887 patients who were receiving TNF-α antagonists between August2005 and June 2015 were evaluated...
October 13, 2017: Clinical Respiratory Journal
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"