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Beta Glucans

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https://www.readbyqxmd.com/read/29755492/common-features-between-the-proteomes-of-floral-and-extrafloral-nectar-from-the-castor-plant-ricinus-communis-and-the-proteomes-of-exudates-from-carnivorous-plants
#1
Fábio C S Nogueira, Andreza R B Farias, Fabiano M Teixeira, Gilberto B Domont, Francisco A P Campos
Label-free quantitative proteome analysis of extrafloral (EFN) and floral nectar (FN) from castor ( Ricinus communis ) plants resulted in the identification of 72 and 37 proteins, respectively. Thirty proteins were differentially accumulated between EFN and FN, and 24 of these were more abundant in the EFN. In addition to proteins involved in maintaining the nectar pathogen free such as chitinases and glucan 1,3-beta-glucosidase, both proteomes share an array of peptidases, lipases, carbohydrases, and nucleases...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29734706/phenotypic-and-physiological-evaluation-of-two-and-six-rows-barley-under-different-environmental-conditions
#2
Mahmoud Naser, Mohamed Badran, Hanaa Abouzied, Heba Ali, Ibrahim Elbasyoni
In recent years, barley has attracted more interest as a food and feed source because of its high soluble dietary fiber and β-glucan content compared with other small grains. Twenty-five barley genotypes (20 imported genotypes and five check cultivars) were grown in three environments for two successive seasons: 2015/2016 and 2016/2017. The first environment was in El-Nubaria, Alexandria, Egypt during 2015/2016, while the second and third environments were in El-Bostan, Elbhera, Egypt during 2015/2016 and 2016/2017...
May 4, 2018: Plants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29724391/the-association-between-endotoxin-and-beta-1-%C3%A2-3-d-glucan-in-house-dust-with-asthma-severity-among-schoolchildren
#3
Oluwafemi Oluwole, Donna C Rennie, Ambikaipakan Senthilselvan, Roland Dyck, Anna Afanasieva, Shelley Kirychuk, George Katselis, Joshua A Lawson
BACKGROUND: Asthma severity can be affected by microbial exposures. However, less is known about the specific indoor agents aggravating the disease in children. We examined the associations between indoor endotoxin and beta-(1 → 3)-D-glucan exposures and asthma severity in children with asthma. METHODS: A clinical cross-sectional study of schoolchildren (aged 7-17 years) was conducted in the province of Saskatchewan, Canada. Children with asthma (n = 116) were identified from 335 participants using a combination of survey responses and objective clinical assessments...
May 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29710434/improved-hcp-reduction-using-a-new-all-synthetic-depth-filtration-media-within-an-antibody-purification-process
#4
Hoang C Nguyen, Amie L Langland, John P Amara, Michael Dullen, David S Kahn, Joseph A Costanzo
Biologic manufacturing processes typically employ clarification technologies like depth filtration to remove insoluble and soluble impurities. Conventional depth filtration media used in these processes contain naturally-derived components like diatomaceous earth and cellulose. These components may introduce performance variability and contribute extractable/leachable components like beta-glucans that could interfere with limulus amebocyte lysate endotoxin assays. Recently a novel, all-synthetic depth filtration media was developed (Millistak+® HC Pro X0SP) that may improve process consistency, efficiency, and drug substance product quality by reducing soluble process impurities...
April 30, 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29684456/radioprotective-effect-of-orally-administered-beta-d-glucan-derived-from-saccharomyces-cerevisiae
#5
Fang Liu, Zhuanzi Wang, Jia Liu, Wenjian Li
The present study was to evaluate the in vivo radioprotective effect of oral administration of Saccharomyces cerevisiae-derived-beta-d-glucan (S. cerevisiae-BG) and to investigate the protective mechanism. The results demonstrated that oral pretreatment with 350 mg/kg S. cerevisiae-BG once daily for 14 consecutive days significantly increased the survival rate of mice from 6 Gy X-rays irradiation. At the 30th day after irradiation, cellularity and the percentage of hematopoietic stem/progenitor cells in bone marrow (BM) of surviving mice were increased by S...
April 20, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29655683/bronchodilator-effects-of-lignosus-rhinocerotis-extract-on-rat-isolated-airways-is-linked-to-the-blockage-of-calcium-entry
#6
Mei-Kee Lee, Kuan-Hon Lim, Paul Millns, Suresh Kumar Mohankumar, Szu-Ting Ng, Chon-Seng Tan, Sue-Mian Then, Yvonne Mbaki, Kang-Nee Ting
BACKGROUND: Lignosus rhinocerotis (Cooke) Ryvarden is a popular medicinal mushroom used for centuries in Southeast Asia to treat asthma and chronic cough. The present study aimed to investigate the effect of this mushroom on airways patency. MATERIALS AND METHODS: The composition of L. rhinocerotis TM02 cultivar was analyzed. Organ bath experiment was employed to study the bronchodilator effect of Lignosus rhinocerotis cold water extract (CWE) on rat isolated airways...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29648596/unraveling-synthesis-of-the-cryptococcal-cell-wall-and-capsule
#7
Zhuo A Wang, Lucy X Li, Tamara L Doering
Fungal pathogens cause devastating infections in millions of individuals each year, representing a huge but underappreciated burden on human health. One of these, the opportunistic fungus Cryptococcus neoformans, kills hundreds of thousands of patients annually, disproportionately affecting people in resource-limited areas. This yeast is distinguished from other pathogenic fungi by a polysaccharide capsule that is displayed on the cell surface. The capsule consists of two complex polysaccharide polymers: a mannan substituted with xylose and glucuronic acid, and a galactan with galactomannan side chains that bear variable amounts of glucuronic acid and xylose...
April 10, 2018: Glycobiology
https://www.readbyqxmd.com/read/29604620/supplementation-of-caricol%C3%A2-gastro-reduces-chronic-gastritis-disease-associated-pain
#8
Friedrich-Anton Weiser, Michael Fangl, Wilhelm Mosgoeller
OBJECTIVE: Papaya and oats are natural food and used in traditional medicine in many parts of the world. Papaya has a high content of enzymes supporting digestive function. Oats are a source of minerals, beta-glucan fibres, immunmodulatory and antiinflammatory probiotic substances. Caricol®-Gastro combines both constituents, it was designed as vegan organic preparation for intestinal inflammatory diseases. We performed a randomized, double blind placebo controlled clinical trial to investigate the potential of Caricol®-Gastro as add on therapy in patients with diagnosed chronic gastritis...
March 1, 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29579935/characterization-of-oat-beta-glucan-and-coenzyme-q10-loaded-beta-glucan-powders-generated-by-the-pressurized-gas-expanded-liquid-pgx-technology
#9
Nian Liu, Ricardo Couto, Bernhard Seifried, Paul Moquin, Luis Delgado, Feral Temelli
The physicochemical properties of the oat beta-glucan powder (BG) and coenzyme Q10 (CoQ10)-loaded BG powder (L-BG) produced by the pressurized gas-expanded liquid (PGX) technology were studied. Helium ion microscope, differential scanning calorimeter, X-ray diffractometer, AutoSorb iQ and rheometer were used to determine the particle morphology, thermal properties, crystallinity, surface area and viscosity, respectively. Both BG (7.7μm) and L-BG (6.1μm) were produced as micrometer-scale particles, while CoQ10 nanoparticles (92nm) were adsorbed on the porous structure of L-BG...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29528125/development-of-an-orange-juice-beverage-formulated-with-oat-beta-glucan-and-whey-protein-isolate
#10
Wenjing Wan, Baojun Xu
BACKGROUND: A beverage was developed using beta-glucan and whey protein isolate (WPI). The sensory attributes and changes of the physiochemical properties (pH value, total acidity, total soluble solids, sugar-acid ratio, color, viscosity, turbidity, and browning index) of the beverage during 48-h storage were evaluated by comparison with the commercial product and a blank sample. RESULTS: The sweetness, smoothness, and overall acceptance of the developed beverage were similar to the commercial and blank samples...
March 12, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29524446/beta-glucan-enhances-the-response-to-svcv-infection-in-zebrafish
#11
Regla M Medina-Gali, María Del Mar Ortega-Villaizan, Luis Mercado, Beatriz Novoa, Julio Coll, Luis Perez
The antiviral effects of beta-glucan, an immunostimulatory agent were studied in zebrafish both in vitro and in vivo. Here we show that zebrafish ZF4 cells as well as whole fish primed with yeast β-glucan zymosan exhibited increased cytokine expression and elevated response to spring viremia of carp virus (SVCV) infection. In vitro, previous treatment of β-glucan enhanced ZF4 cell viability against SVCV infection which is associated to the activation of interferon signaling pathway and inflammatory cytokines gene expression...
July 2018: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29486797/a-randomized-controlled-trial-evaluating-the-efficacy-and-safety-of-bth1677-in-combination-with-bevacizumab-carboplatin-and-paclitaxel-in-first-line-treatment-of-advanced-non-small-cell-lung-cancer
#12
Walburga Engel-Riedel, Jamie Lowe, Paulette Mattson, J Richard Trout, Richard D Huhn, Michele Gargano, Myra L Patchen, Richard Walsh, My My Trinh, Mariève Dupuis, Folker Schneller
BACKGROUND: BTH1677, a beta-glucan pathogen-associated molecular pattern molecule, drives an anti-cancer immune response in combination with oncology antibody therapies. This phase II study explored the efficacy, pharmacokinetics (PK), and safety of BTH1677 combined with bevacizumab/carboplatin/paclitaxel in patients with untreated advanced non-small cell lung cancer (NSCLC). METHODS: Patients were randomized to the BTH1677 arm (N = 61; intravenous [IV] BTH1677, 4 mg/kg, weekly; IV bevacizumab, 15 mg/kg, once each 3-week cycle [Q3W]; IV carboplatin, 6 mg/mL/min Calvert formula area-under-the-curve, Q3W; and IV paclitaxel, 200 mg/m2 , Q3W) or Control arm (N = 31; bevacizumab/carboplatin/paclitaxel as above)...
February 27, 2018: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29485753/a-novel-meloidogyne-graminicola-effector-mgmo237-interacts-with-multiple-host-defence-related-proteins-to-manipulate-plant-basal-immunity-and-promote-parasitism
#13
Jiansong Chen, Lili Hu, Longhua Sun, Borong Lin, Kun Huang, Kan Zhuo, Jinling Liao
Plant-parasitic nematodes can secrete effector proteins into the host tissue to facilitate their parasitism. In this study, we report a novel effector protein, MgMO237, from Meloidogyne graminicola, which is exclusively expressed within the dorsal oesophageal gland cell and markedly up-regulated in parasitic third-/fourth-stage juveniles of M. graminicola. Transient expression of MgMO237 in protoplasts from rice roots showed that MgMO237 was localized in the cytoplasm and nucleus of the host cells. Rice plants overexpressing MgMO237 showed an increased susceptibility to M...
February 27, 2018: Molecular Plant Pathology
https://www.readbyqxmd.com/read/29467823/in-vitro-and-in-vivo-characterization-of-three-cellvibrio-japonicus-glycoside-hydrolase-family-5-members-reveals-potent-xyloglucan-backbone-cleaving-functions
#14
Mohamed A Attia, Cassandra E Nelson, Wendy A Offen, Namrata Jain, Gideon J Davies, Jeffrey G Gardner, Harry Brumer
Background: Xyloglucan (XyG) is a ubiquitous and fundamental polysaccharide of plant cell walls. Due to its structural complexity, XyG requires a combination of backbone-cleaving and sidechain-debranching enzymes for complete deconstruction into its component monosaccharides. The soil saprophyte Cellvibrio japonicus has emerged as a genetically tractable model system to study biomass saccharification, in part due to its innate capacity to utilize a wide range of plant polysaccharides for growth...
2018: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29435400/encapsulation-of-cadmium-selenide-nanocrystals-in-biocompatible-nanotubes-dft-calculations-x-ray-diffraction-investigations-and-confocal-fluorescence-imaging
#15
David G Calatayud, Haobo Ge, Navaratnarajah Kuganathan, Vincenzo Mirabello, Robert M J Jacobs, Nicholas H Rees, Craig T Stoppiello, Andrei N Khlobystov, Rex M Tyrrell, Enrico Da Como, Sofia I Pascu
The encapsulation of CdSe nanocrystals within single-walled carbon nanotube (SWNT) cavities of varying dimensions at elevated temperatures under strictly air-tight conditions is described for the first time. The structures of CdSe nanocrystals under confinement inside SWNTs was established in a comprehensive study, combining both experimental and DFT theoretical investigations. The calculated binding energies show that all considered polymorphs [(3:3), (4:4), and (4:2)] may be obtained experimentally. The most thermodynamically stable structure (3:3) is directly compared to the experimentally observed CdSe structures inside carbon nanotubes...
February 2018: ChemistryOpen
https://www.readbyqxmd.com/read/29373751/inferring-putative-virulence-factors-for-pythium-insidiosum-by-proteomic-approach
#16
Jéssica Luana Chechi, Tarsila Franckin, Lidiane Nunes Barbosa, Fernanda Cristina Bérgamo Alves, Aline de Lima Leite, Marília Afonso Rabelo Buzalaf, Lucilene Delazari Dos Santos, Sandra de Moraes Gimenes Bosco
Pythium insidiosum is the etiologic agent of pythiosis, a life-threatening disease that affects human and animals, has difficult diagnosis, and therapy. Studies on protein characterization of P. insidiosum are scarce, so we aimed to determine the protein profile of P. insidiosum by mass spectrometry and bioinformatics strategies targeting in proteins that may act as putative virulence factors. Therefore, an extraction protocol was standardized to obtain the total proteins of P. insidiosum. By the analysis of Image Master 2D Platinum software, it was found that 186 spots ranging between 12 and 89 KDa and isoelectric point from 4 to 7...
January 23, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29370030/beta-d-glucan-testing-in-patients-with-fungal-endophthalmitis
#17
Anton M Kolomeyer, Kathleen M Murphy, Anastasia Traband, Ian Frank, Benjamin J Kim
PURPOSE: To review the literature on beta-D-glucan (BDG) testing in fungal endophthalmitis. METHODS: Review of primary literature using PubMed through April 2017 and presentation of an illustrative case report. A total of 231 articles were identified and 43 were ultimately chosen for review based on relevance and presence of ophthalmologic examination and objective data. RESULTS: Beta-D-glucan is a major component of fungal cell walls. It is quantified using a calorimetry-based Fungitell assay based on modification of the limulus amebocyte lysate...
April 2018: Retina
https://www.readbyqxmd.com/read/29363342/the-effect-of-beta-glucan-on-mtx-induced-testicular-damage-in-rats
#18
F Koc, Z Erısgın, Y Tekelıoglu, S Takır
We investigated the histopathological effects of methotrexate (MTX), a chemotherapeutic agent, and beta glucan (BG), an antioxidant, on rat testis. We used four groups of Sprague-Dawley male rats: MTX, MTX + BG, BG, and control. The MTX group was exposed to a single dose of MTX on the first day of experiment. The MTX + BG group was exposed to a single dose of MTX and BG on the first day of experiment followed by BG for 4 additional days. The BG group was exposed to BG for 5 days. The control group was given saline for 5 days...
January 24, 2018: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/29358800/effects-of-beta-glucan-and-resistant-starch-on-wheat-dough-and-prebiotic-bread-properties
#19
Zahra Mohebbi, Aziz Homayouni, Mohammad Hossein Azizi, Sayyed Javad Hosseini
White wheat flour is a poor source of dietary fiber. Therefore a demand exists for enrichment of bread with non-digestible prebiotic ingredients that exert health-promoting effects. In this study, the effects of beta-glucan (BG) and resistant starch (RS) on the dough properties and bread-making characteristics were investigated. The water absorption of doughs increased with increasing BG and RS levels. Also, development time and farinograph quality number of BG-enriched doughs remained similar to that of the control while the doughs stability decreased, and all of these values decreased when the RS was added...
January 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29356277/assessment-of-the-efficacy-of-a-new-complex-antisensitive-skin-cream
#20
Yinjuan Wang, Céline Viennet, Adeline Jeudy, Ferial Fanian, Li He, Philippe Humbert
BACKGROUND: Sensitive skin is frequently complaint in dermatology consultation with cutaneous manifestations such as stinging, redness, dryness, and burning sensation that affect the quality of life. Its pathogenesis is mainly related to dysfunction of neurosensory, skin barrier, and also immune activity. The treatment is generally based on continuous and topical therapy by nonirritating complex. OBJECTIVE: To evaluate the antisensitive function of a new complex cream composed by Yunnan Portulaca oleracea extract, Prinsepia utilis oil, beta-glucan, and sodium hyaluronate extracted from mushroom...
January 22, 2018: Journal of Cosmetic Dermatology
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