Cláudia B A Medeiros, Iasmim Lopes de Lima, Thiago Barbosa Cahú, Bruna R Muniz, Maria Helena M L Ribeiro, Érico Higino de Carvalho, Marcos Nogueira Eberlin, Marcelo J B Miranda, Ranilson de Souza Bezerra, Roberto Afonso da Silva, José Luiz de Lima Filho
Full-thickness cutaneous trauma, due to the lack of dermis, leads to difficulty in epithelialization by keratinocytes, developing a fibrotic scar, with less elasticity than the original skin, which may have disorders in predisposed individuals, resulting in hypertrophic scar and keloids. Biomedical materials have excellent characteristics, such as good biocompatibility and low immunogenicity, which can temporarily replace traditional materials used as primary dressings. In this work, we developed two dermal matrices based on Nile tilapia collagen, with (M_GAG) and without (M) glycosaminoglycans, using a sugarcane polymer membrane as a matrix support...
January 2024: Journal of Mass Spectrometry: JMS