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"svc flow" and neonate

Benjamim Ficial, Elena Bonafiglia, Ezio M Padovani, Maria A Prioli, Anna E Finnemore, David J Cox, Kathryn M Broadhouse, Anthony N Price, Giuliana Durighel, Alan M Groves
OBJECTIVE: To assess accuracy and repeatability of a modified echocardiographic approach to quantify superior vena cava (SVC) flow volume that uses a short-axis view to directly measure SVC area and a suprasternal view to measure flow velocity, both at the level of the right pulmonary artery. SETTING: Three tertiary-level neonatal intensive care units. DESIGN: This was a multicentre, prospective, observational study. Accuracy of the traditional and modified approach was first assessed by comparing echo measurements according to both techniques with Phase contrast MRI (PCMRI) assessments, in a cohort of 10 neonates...
May 26, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
Anil Lakkundi, Ian Wright, Koert de Waal
BACKGROUND: Early respiratory management of very low birth weight infants has changed over recent years to a practice of early use of CPAP with early selective surfactant administration, and decreased use of mechanical ventilation. One strategy is to use the combination of surfactant and prompt extubation to nasal continuous positive airway pressure (INtubate, SURfactant, Extubate, or INSURE). The aim of this study is to describe blood flow and ductal flow in a prospective cohort during the transitional period when this respiratory management strategy is used...
August 2014: Early Human Development
Richelle N Olsen, Jennifer Shepherd, Anup Katheria
Objective. Abnormal umbilical artery Doppler (UAD) studies are associated with poor neonatal outcomes. We sought to determine if postnatal measures of systemic blood flow (SBF), as measured by functional echocardiography (fECHO), could identify which fetuses with abnormal UAD were at the highest risk of adverse outcomes. Study Design. This is a retrospective review of fetuses with abnormal UAD who received fECHO in the first 72 hours of life. Measures of SBF (right ventricular output (RVO) and superior vena cava (SVC) flow) were performed and compared with prenatal variables and postnatal outcomes...
2014: ISRN Obstetrics and Gynecology
Ori Hochwald, Mohammad Jabr, Horacio Osiovich, Steven P Miller, Patrick J McNamara, Pascal M Lavoie
OBJECTIVE: To determine the relationship between left ventricular cardiac output (LVCO), superior vena cava (SVC) flow, and brain injury during whole-body therapeutic hypothermia. STUDY DESIGN: Sixteen newborns with moderate or severe hypoxic-ischemic encephalopathy were studied using echocardiography during and immediately after therapeutic hypothermia. Measures were also compared with 12 healthy newborns of similar postnatal age. Newborns undergoing therapeutic hypothermia also had cerebral magnetic resonance imaging as part of routine clinical care on postnatal day 3-4...
May 2014: Journal of Pediatrics
K König, K J Guy, G Walsh, S M Drew, A Watkins, C P Barfield
OBJECTIVE: Preterm infants are at risk of circulatory compromise following birth. Functional neonatal echocardiography including superior vena cava (SVC) flow is increasingly used in neonatal medicine, and low SVC flow has been associated with adverse outcome. However, echocardiography is not readily available in many neonatal units and B-type natriuretic peptides (BNPs) may be useful in guiding further cardiovascular assessment. This study investigated the relationship between BNP, N-terminal pro-BNP (NTproBNP) and echocardiographic measurements of systemic blood flow in very preterm infants...
April 2014: Journal of Perinatology: Official Journal of the California Perinatal Association
Nishant Banait, Pradeep Suryawanshi, Nandini Malshe, Rema Nagpal, Sanjay Lalwani
BACKGROUND: Cardiac blood flow measurements are useful in the haemodynamic management of neonates. Cardiac blood flows can be estimated with functional echocardiography as follows; flow in Superior Vena Cava (SVC), Right Ventricular Outflow (RVO) and Left Ventricular Outflow (LVO). Studies in preterm infants have shown that abnormal superior vena cava flow is associated with poor neurodevelopmental outcomes. To date, normative data on LVO, RVO and SVC flows has been established for term appropriate for gestational age neonates and preterm neonates, but no data is available on RVO, LVO and SVC flows for term small for gestational age neonates...
August 2013: Journal of Clinical and Diagnostic Research: JCDR
Dharmesh Shah, Mary Paradisis, Jennifer R Bowen
BACKGROUND: Significant hemodynamic changes occur immediately after birth in preterm infants. Amplitude-integrated electroencephalography (aEEG) provides a method of assessing brain activity in sick neonates; however, the relationship among systemic blood flow, blood pressure (BP), and aEEG is not clear. METHODS: Quantitative measures of aEEG continuity and amplitude were correlated with superior vena cava (SVC) flow, right-ventricular output (RVO), and BP at 12, 24, and 48 h in 92 infants born at <29 wk gestation...
September 2013: Pediatric Research
J Sirc, E M Dempsey, J Miletin
BACKGROUND: Near-infrared spectroscopy is a non-invasive method of assessing cerebral oxygenation. Functional echocardiography is increasingly used by neonatologists in the assessment of cardiovascular function. AIMS: To correlate cerebral tissue oxygenation index (cTOI) and cardiac output in infants less than 1250 g at 6, 12, 24 and 48 hours of age. STUDY DESIGN: A prospective observational study. SUBJECTS: Newborns with birth weight<1250 g...
July 2013: Early Human Development
Takeshi Kumagai, Ryuzo Higuchi, Asumi Higa, Yoshinobu Tsuno, Chisako Hiramatsu, Takuya Sugimoto, Mina Booka, Takahiro Okutani, Norishige Yoshikawa
OBJECTIVES: To assess the relationship between superior vena cava (SVC) flow and short-term outcome in infants with perinatal asphyxia. METHODS: Infants in sequence born after more than 35 weeks of gestation who had been hospitalized at the NICU and normal neonatal wards of Wakayama Medical University between May 2005 and September 2010 were recruited for this observational cohort study. The study eligibility criterion was the presence of perinatal asphyxia, as evidenced by abnormal fetal heart rate monitoring and an Apgar score of 7 or less at 1 min or need for resuscitation using positive pressure ventilation...
May 2013: Early Human Development
Andrei Harabor, Deborah Fruitman
OBJECTIVES: Superior vena cava (SVC) flow is becoming an important hemodynamic measurement in neonates through its use in targeted neonatal echocardiography. Previous studies measured the flow velocity in the SVC through an abdominal approach. In adults and children, the abdominal and the suprasternal or high parasternal window are considered equivalent. We compared the two approaches in neonates. Our hypothesis was that the two echocardiographic approaches would yield similar results...
December 2012: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Anne Marie Heuchan, Jo Bhattacharyha
OBJECTIVE: Vein of Galen malformation (VGAM) in neonates presents a complex management challenge. Measurement of superior vena cava (SVC) blood flow may provide insights into the haemodynamics of VGAM and the effects of therapeutic intervention. METHODS: SVC flow was assessed in 15 neonates with VGAM. SVC flow results, Bicêtre scores (clinical assessment), echocardiographic assessment and clinical outcomes are presented. RESULTS: SVC flows (166-581 ml/kg/min) were significantly elevated at presentation (p<0...
September 2012: Archives of Disease in Childhood. Fetal and Neonatal Edition
James R Holberton, Sandra M Drew, Rintaro Mori, Kai König
Low superior vena cava (SVC) flow has been associated with intraventricular haemorrhage (IVH) in very preterm infants. We studied the diagnostic value of a single measurement of SVC flow within the first 24 h of life in very preterm infants and its association with occurrence or extension of IVH in a setting of limited availability of neonatal echocardiography. Preterm infants who were born at less than 30 weeks gestation and who had an echocardiogram within 24 h after birth were eligible. Baseline, clinical and ultrasound data were collected...
October 2012: European Journal of Pediatrics
M Paradisis, D A Osborn, N Evans, M Kluckow
OBJECTIVE: Use of antenatal magnesium sulfate (MgSO(4)) may reduce cerebral palsy in infants born very preterm. Low systemic blood flow in the first day in very preterm infants has been associated with cerebral injury and adverse motor outcome. The aim was to determine the effect of MgSO(4) on systemic blood flow in preterm infants. STUDY DESIGN: Randomized trial of MgSO(4) versus saline placebo given to mothers at risk of delivery before 30 weeks gestation. Echocardiographic monitoring performed at 3 to 5, 10 to 12 and 24 h...
September 2012: Journal of Perinatology: Official Journal of the California Perinatal Association
Akio Ishiguro, Takashi Sekine, Keiji Suzuki, Clara Kurishima, Shoichi Ezaki, Tetsuya Kunikata, Hisanori Sobajima, Masanori Tamura
BACKGROUND: Conventional parameters of circulation that are routinely used in neonatal intensive care units, including blood pressure, have been reported to be inadequate in improving prognosis of very-low-birth-weight (VLBW) infants. Recently, the importance of evaluating the blood flow to each organ, including both vital and nonvital organs, has been increasingly recognized. OBJECTIVES: To study the changes in peripheral perfusion occurring in VLBW infants of less than 32 weeks' gestation during the extrauterine transitional period...
2011: Neonatology
Takeshi Takami, Daisuke Sunohara, Atsushi Kondo, Norio Mizukaki, Yuusuke Suganami, Yukito Takei, Tasuku Miyajima, Akinori Hoshika
Cerebral perfusion and its relation with systemic circulation in extremely LBW (ELBW) infants in the early neonatal period are not well understood. The cerebral tissue oxygenation index (TOI) and cerebral fractional tissue oxygen extraction (FTOE) were monitored in stable 16 ELBW infants (GA <29 wk) using near-infrared spectroscopy (NIRS) at 3-6, 12, 18, 24, 36, 48, and 72 h after birth. The left ventricular end-systolic wall stress (ESWS), left ventricular ejection fraction (LVEF), left ventricular cardiac output (LVCO), and superior vena cava (SVC) flow were also measured simultaneously using echocardiography...
November 2010: Pediatric Research
J Miletin, K Pichova, S Doyle, E M Dempsey
OBJECTIVE: Recent evidence suggests that high cortisol concentrations are associated with increased morbidity and mortality in very low birth weight (VLBW) infants. Neonatal illness severity and mortality risk scores are reliable in predicting morbidity and mortality. The objectives were (i) to assess the correlation between serum cortisol levels and clinical assessment of multi-organ dysfunction/illness severity scores (CRIB II, SNAPPE-II and neonatal multiple organ dysfunction score (NEOMOD)) in first 24 h in VLBW infants and (ii) to assess the relationship between surrogates of end organ blood flow and serum cortisol levels...
August 2010: Journal of Perinatology: Official Journal of the California Perinatal Association
Koert de Waal, Nick Evans
OBJECTIVE: To describe the hemodynamic changes with time in preterm infants with clinical sepsis. STUDY DESIGN: Blood pressure, right ventricular output (RVO), left ventricular output (LVO), and superior vena cava (SVC) flow of infants who had a suspected infection and showed signs of cardiovascular compromise were measured every 12 hours or until there was considered clinical improvement. RESULTS: Twenty infants with a median gestational age of 27 weeks (range, 25-32 weeks) and weight of 995 g (range, 650-1980 g) were examined...
June 2010: Journal of Pediatrics
A Lee, K Liestøl, E Nestaas, L Brunvand, R Lindemann, D Fugelseth
BACKGROUND: Superior vena cava (SVC) flow has become a surrogate measure of systemic blood flow in neonates. OBJECTIVE: The aim of this study was to establish normal SVC flow values in healthy term infants the first 3 days of life and to evaluate the feasibility and reliability of the off-line analyses. DESIGN: Doppler echocardiography of SVC flow was performed in 48 healthy term infants the first 3 days of life. Off-line analyses were thereafter performed by one cardiologist to investigate the changes in SVC flow from day 1 to day 3 and to establish normal values...
March 2010: Archives of Disease in Childhood. Fetal and Neonatal Edition
S Takahashi, S Kakiuchi, Y Nanba, K Tsukamoto, T Nakamura, Y Ito
OBJECTIVE: Superior vena cava (SVC) flow is used as an index for evaluating systemic blood flow in neonates. Thus far, several reports have shown that low SVC flow is a risk factor for intraventricular hemorrhage (IVH) in the preterm infant. Therefore, it is likely to be a useful index in the management of the preterm infant. The perfusion index (PI) derived from a pulse oximeter is a marker that allows noninvasive and continuous monitoring of peripheral perfusion. The objective of this paper was to determine the accuracy of the PI for detecting low SVC flow in very low birth weight infants born before 32 weeks of gestation...
April 2010: Journal of Perinatology: Official Journal of the California Perinatal Association
M Moran, J Miletin, K Pichova, E M Dempsey
BACKGROUND: Superior vena cava (SVC) flow assesses blood flow from the upper body, including the brain. Near infrared spectroscopy (NIRS) provides information on brain perfusion and oxygenation. AIM: To assess the relationship between cerebral tissue oxygenation index (cTOI) and cardiac output measures in the very low birth weight (VLBW) infant in the first day of life. METHODS: A prospective observational cohort study. Neonates with birth weight less than 1500 g (VLBW) were eligible for enrollment...
January 2009: Acta Paediatrica
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