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https://www.readbyqxmd.com/read/28933906/neural-bases-of-automaticity
#1
Mathieu Servant, Peter Cassey, Geoffrey F Woodman, Gordon D Logan
Automaticity allows us to perform tasks in a fast, efficient, and effortless manner after sufficient practice. Theories of automaticity propose that across practice processing transitions from being controlled by working memory to being controlled by long-term memory retrieval. Recent event-related potential (ERP) studies have sought to test this prediction, however, these experiments did not use the canonical paradigms used to study automaticity. Specifically, automaticity is typically studied using practice regimes with consistent mapping between targets and distractors and spaced practice with individual targets, features that these previous studies lacked...
September 21, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28931750/adrenal-gipr-expression-and-chromosome-19q13-microduplications-in-gip-dependent-cushing-s-syndrome
#2
Anne-Lise Lecoq, Constantine A Stratakis, Say Viengchareun, Ronan Chaligné, Lucie Tosca, Vianney Deméocq, Mirella Hage, Annabel Berthon, Fabio R Faucz, Patrick Hanna, Hadrien-Gaël Boyer, Nicolas Servant, Sylvie Salenave, Gérard Tachdjian, Clovis Adam, Vanessa Benhamo, Eric Clauser, Anne Guiochon-Mantel, Jacques Young, Marc Lombès, Isabelle Bourdeau, Dominique Maiter, Antoine Tabarin, Jérôme Bertherat, Hervé Lefebvre, Wouter de Herder, Estelle Louiset, André Lacroix, Philippe Chanson, Jérôme Bouligand, Peter Kamenický
GIP-dependent Cushing's syndrome is caused by ectopic expression of glucose-dependent insulinotropic polypeptide receptor (GIPR) in cortisol-producing adrenal adenomas or in bilateral macronodular adrenal hyperplasias. Molecular mechanisms leading to ectopic GIPR expression in adrenal tissue are not known. Here we performed molecular analyses on adrenocortical adenomas and bilateral macronodular adrenal hyperplasias obtained from 14 patients with GIP-dependent adrenal Cushing's syndrome and one patient with GIP-dependent aldosteronism...
September 21, 2017: JCI Insight
https://www.readbyqxmd.com/read/28930100/the-joule-heating-problem-in-silver-nanowire-transparent-electrodes
#3
H H Khaligh, L Xu, A Khosropour, A Madeira, M Romano, C Pradére, M Tréguer-Delapierre, L Servant, M A Pope, I A Goldthorpe
Silver nanowire transparent electrodes have shown considerable potential to replace conventional transparent conductive materials. However, in this report we show that Joule heating is a unique and serious problem with these electrodes. When conducting current densities encountered in organic solar cells, the average surface temperature of indium tin oxide (ITO) and silver nanowire electrodes, both with sheet resistances of 60 ohms/square, remains below 35 °C. However, in contrast to ITO, the temperature in the nanowire electrode is very non-uniform, with some localized points reaching temperatures above 250 °C...
September 20, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28920515/quality-of-life-in-women-of-reproductive-age-a-comparative-study-of-infertile-and-fertile-women-in-a-nigerian-tertiary-centre
#4
Olusola Peter Aduloju, Oluwole Dominic Olaogun, Tolulope Aduloju
The study examined the quality of life in women of reproductive age and the aim was to evaluate and compare the quality of life (QoL) scores among fertile and infertile women. A cross-sectional study was carried out among women attending the Gynaecology and Postnatal Clinics of Ekiti State University Teaching Hospital comparing their QoL using the World Health Organisation Quality of Life-BREF (WHOQOL-BREF) questionnaire. The age of fertile women was significantly higher than the age of infertile women (p < ...
September 18, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28900047/serving-following-and-leading-in-health-care
#5
Steven M Penny
Radiologic technologists often perform diverse roles throughout the workday, and they should have at least a minimal understanding of the responsibility and effects of these roles on the patient and organization. Although technologists can practice independently or as part of a work group, individuals should be prepared to improve patient care and to function as a servant, follower, and leader for the overall success of the organization. This article examines those roles, emphasizing servantship.
July 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28893557/transcription-factor-cux1-is-required-for-intestinal-epithelial-wound-healing-and-targets-the-vav2-rac1-signalling-complex
#6
Roxanne Latreille, Raphaëlle Servant, Mathieu Darsigny, Sébastien Marcoux, Christine Jones, Nathalie Perreault, François Boudreau
Intestinal epithelial cells form a protective barrier in limiting gut luminal content potentially harmful to the host. Upon gut epithelium injury, several signals instruct epithelial cells to undergo a rapid healing process. Defects in this process induce inflammatory responses and can further evolve into chronic gut inflammatory diseases. We previously identified the transcription factor CUX1 as crucial for protecting against experimental colitis in mice. However, the precise molecular mechanisms by which CUX1 intervenes during this biological process are unknown...
September 8, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28891885/the-association-board-as-servant-leader
#7
Patsy Maloney
No abstract text is available yet for this article.
September 2017: Journal for Nurses in Professional Development
https://www.readbyqxmd.com/read/28877942/changes-in-mortality-inequalities-across-occupations-in-japan-a-national-register-based-study-of-absolute-and-relative-measures-1980-2010
#8
Hirokazu Tanaka, Satoshi Toyokawa, Nanako Tamiya, Hideto Takahashi, Haruko Noguchi, Yasuki Kobayashi
OBJECTIVE: Changes in mortality inequalities across socioeconomic groups have been a substantial public health concern worldwide. We investigated changes in absolute/relative mortality inequalities across occupations, and the contribution of different diseases to inequalities in tandem with the restructuring of the Japanese economy. METHODS: Using complete Japanese national death registries from 5 year intervals (1980-2010), all cause and cause specific age standardised mortality rates (ASMR per 100 000 people standardised using the Japanese standard population in 1985, aged 30-59 years) across 12 occupations were computed...
September 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28854972/willingness-to-pay-for-national-health-insurance-fund-among-public-servants-in-juba-city-south-sudan-a-contingent-evaluation
#9
Robert Basaza, Paul Kon Alier, Peter Kirabira, David Ogubi, Richard Lino Loro Lako
BACKGROUND: This study assessed willingness to pay for National Health Insurance Fund (NHIF) among public servants in Juba City. NHIF is the proposed health insurance scheme for South Sudan and aims at achieving universal health coverage for the entire nation's population. One compounding issue is that over the years, governments' spending on healthcare has been decreasing from 8.4% of national budget in 2007 to only 2.2% in 2012. METHODS: A cross-sectional study design using contingent evaluation was employed; data on willingness to pay was collected from 381 randomly selected respondents and 13 purposively selected key informants working for the national, state and Juba County in September 2015...
August 30, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28843950/an-evaluation-of-knowledge-and-attitudes-toward-epilepsy-in-eastern-turkey
#10
Emine Kiyak, Nuray Dayapoglu
PURPOSE: This study was designed to determine the knowledge and attitudes regarding epilepsy among individuals in eastern Turkey. METHOD: This descriptive study involved 530 healthy individuals who came to the Research and Application Hospital of Ataturk University in Erzurum, Turkey. A questionnaire and the epilepsy knowledge and attitude scale were administered to collect data. Mann-Whitney U, Kruskal-Wallis, and Spearman's correlation tests were used to analyze the data...
August 23, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28836972/access-to-medicines-and-diagnostic-tests-integral-in-the-management-of-diabetes-mellitus-and-cardiovascular-diseases-in-uganda-insights-from-the-accodad-study
#11
Davis Kibirige, David Atuhe, Leaticia Kampiire, Daniel Ssekikubo Kiggundu, Pamela Donggo, Juliet Nabbaale, Raymond Mbayo Mwebaze, Robert Kalyesubula, William Lumu
BACKGROUND: Despite the burgeoning burden of diabetes mellitus (DM) and cardiovascular diseases (CVD) in low and middle income countries (LMIC), access to affordable essential medicines and diagnostic tests for DM and CVD still remain a challenge in clinical practice. The Access to Cardiovascular diseases, Chronic Obstructive pulmonary disease, Diabetes mellitus and Asthma Drugs and diagnostics (ACCODAD) study aimed at providing contemporary information about the availability, cost and affordability of medicines and diagnostic tests integral in the management of DM and CVD in Uganda...
August 24, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28833986/science-and-the-great-challenges-for-society
#12
EDITORIAL
Jürgen Kaube
"… What is the purpose of science? Science is not only a method to solve problems but to identify them, thus regarding it as a servant of our civilization is to only half understand its potential. Science is far more one of the pillars of our civilization as it represents the institutionalization of the willingness to learn …" Find out more in the Editorial by Jürgen Kaube.
September 4, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28799159/-the-japanese-health-care-system-an-analysis-of-the-funding-and-reimbursement-system
#13
Alexis Rump, Oliver Schöffski
Objective The modern Japanese health care system was established during the Meiji period (1868-1912) using the example of Germany. In this paper, the funding and remuneration of health services and products in Japan are described. The focus lies on the mechanisms used to implement health policy goals and to control costs. Method Selective literature search. Results All permanent residents in Japan are enrolled in one of more than 3,000 compulsory health funds. Employees and public servants are covered through company or government-related health insurance schemes...
August 10, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28771199/effect-of-job-strain-on-job-burnout-mental-fatigue-and-chronic-diseases-among-civil-servants-in-the-xinjiang-uygur-autonomous-region-of-china
#14
Suzhen Guan, Xiadiya Xiaerfuding, Li Ning, Yulong Lian, Yu Jiang, Jiwen Liu, Tzi Bun Ng
Job strain is a major concern in view of its effects among civil servants associated with job burnout, mental fatigue and chronic diseases. The objective of this study was to assess the job strain level among civil servants and examine the effect of job strain on job burnout, mental fatigue and the resulting chronic diseases. A cross-sectional study with a representative sample consisting of 5000 civil servants was conducted from March to August 2014. Using a structured questionnaire, the job strain level, job burnout and mental fatigue were measured by using the Personal Strain Questionnaire (PSQ), Maslach Burnout Inventory (MBI) and Multidimensional Fatigue Inventory (MFI-20), respectively...
August 3, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28767993/physical-activity-in-brazil-lessons-from-elsa-brasil-narrative-review
#15
Francisco José Gondim Pitanga, Maria Conceição Chagas Almeida, Ciro Oliveira Queiroz, Estela Maria Leão de Aquino, Sheila Maria Alvim Matos
CONTEXT AND OBJECTIVE: The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) was conducted among civil servants at six higher education institutions located in six Brazilian state capitals. The objective of this review was to identify the publications produced within the scope of ELSA-Brasil that analyzed the participants' physical activity. DESIGN AND SETTING: Review study using baseline data from ELSA-Brasil. METHODS: Narrative review of Brazilian studies on physical activity produced using data from ELSA-Brasil participants...
July 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28734088/the-stability-of-baseline-defined-categories-of-alcohol-consumption-over-the-adult-life-course-a-28-year-prospective-cohort-study
#16
Craig S Knott, Steven Bell, Annie Britton
BACKGROUND AND AIMS: Studies that report the relationship between alcohol consumption and disease risk have predominantly operationalised drinking according to a single baseline measure. The resulting assumption of longitudinal stability may be simplistic and complicate interpretation of risk estimates. This study aims to describe changes to the volume of consumption across the adult life course according to baseline categories of drinking. DESIGN: A prospective observational study...
July 22, 2017: Addiction
https://www.readbyqxmd.com/read/28711626/influence-of-metabolic-risk-factors-on-risk-of-hepatocellular-carcinoma-and-liver-related-death-in-men-with-chronic-hepatitis-b-a-large-cohort-study
#17
Ming-Whei Yu, Chih-Lin Lin, Chun-Jen Liu, Shu-Han Yang, Yu-Lin Tseng, Chih-Feng Wu
BACKGROUND & AIMS: Little is known about the absolute risk of hepatocellular carcinoma (HCC) and liver-disease related death, in association with metabolic risk factors, for patients with hepatitis B virus (HBV) infection. METHODS: We collected data from 5373 male Taiwanese civil servants who visited Taiwan's Government Employees' Central Clinics and received routine free physical examinations from 1989 through 1992. We obtained information on liver-related morbidity and mortality in HBV carriers, 40-65 years of age (n=1690), with different metabolic risk factors...
July 12, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28708305/a-novel-variant-of-dhh-in-a-familial-case-of-46-xy-disorder-of-sex-development-insights-from-molecular-dynamics-simulations
#18
Francoise Paris, Delphine Flatters, Sandrine Caburet, Bérangère Legois, Nadège Servant, Hervé Lefebvre, Charles Sultan, Reiner A Veitia
OBJECTIVE: Disorders of sex development (DSD) are a heterogeneous group of conditions affecting the differentiation and development of the internal and external genitalia. Here, we aimed at identifying the genetic cause of DSD in two 46,XY sisters from a consanguineous family. DESIGN: We performed a whole-exome sequencing of two 46,XY female individuals. Sanger sequencing was used to validate the most likely candidate variant, affecting the desert hedgehog (DHH) gene...
July 14, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28670967/prevalence-and-factors-associated-with-alcohol-drinking-among-hiv-and-tuberculosis-co-infected-patients-in-dar-es-salaam-tanzania
#19
Ramadhani Stephano Mwiru, Tumaini Joseph Nagu, Pamela Kaduri, Wafaie Fawzi, Ferdinand Mugusi
There is scarcity of information on the burden of alcohol use among people living with HIV in Tanzania despite the high burden of HIV. We examined the prevalence and factors associated with alcohol use among HIV and tuberculosis (TB) co-infected patients in fourteen clinics with highest notification of TB in Dar es Salaam, Tanzania, between October 2010 and December 2011. Proportions were used to describe the prevalence and pattern of alcohol use. Logistic regression was used to assess the association of various participant characteristics with alcohol use...
July 3, 2017: AIDS Care
https://www.readbyqxmd.com/read/28662813/discovery-and-development-of-a-novel-class-of-phenoxyacetyl-amides-as-highly-potent-trpm8-agonists-for-use-as-cooling-agents
#20
Alain Noncovich, Chad Priest, Jane Ung, Andrew P Patron, Guy Servant, Paul Brust, Nicole Servant, Nathan Faber, Hanghui Liu, Nicole S Gonsalves, Tanya L Ditschun
The paper presents the activity trends for a novel series of phenoxyacetyl amides as human TRPM8 receptor agonists. This series encompasses in vitro activity values ranging from the micromolar to the picomolar levels. Sensory evaluation of these molecules highlights their relevance as cooling agents for oral applications. The positive outcome of the complete evaluation of N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)-2-(p-tolyloxy)acetamide resulted in its approval for Generally Recognized As Safe (GRAS) status by the Flavor & Extract Manufacturer Association (FEMA) as FEMA 4809...
August 15, 2017: Bioorganic & Medicinal Chemistry Letters
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