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lung cancer AND nutrition* AND chemotherapy

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https://www.readbyqxmd.com/read/29569334/determinants-of-quality-of-life-in-lung-cancer-patients
#1
Hsiu-Yu Hung, Li-Min Wu, Kang-Pan Chen
PURPOSE: To examine the relationships of self-care, symptoms, and a variety of demographic factors to quality of life (QOL), and to identify determinants of QOL in lung cancer patients undergoing chemotherapy. DESIGN: A cross-sectional, correlational study. METHODS: 159 patients with lung cancer undergoing chemotherapy were recruited from three southern hospitals in Taiwan. Four instruments were used: the Quality of Life Questionnaire Core 30-item (QLQ-C30), M...
March 23, 2018: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29558830/naturopathic-oncology-care-for-thoracic-cancers-a-practice-survey
#2
Dugald Seely, Julie K Ennis, Ellen McDonell, Linlu Zhao
BACKGROUND AND OBJECTIVES: There is a lack of information on therapies recommended by naturopathic doctors (NDs) for lung and gastroesophageal cancer care. Study objectives were to: (1) identify the most common interventions considered for use by NDs; (2) identify interventions NDs recommend to support key therapeutic goals; and (3) identify potential contraindications between integrative and conventional therapies. METHODS: Oncology Association of Naturopathic Physicians (OncANP) members (n = 351) were invited to complete an electronic survey...
March 1, 2018: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29350696/cancer-anorexia-and-cachexia-screening-in-an-ambulatory-infusion-service-and-nutrition-consultation
#3
Donna L Berry, Traci Blonquist, Manan M Nayak, Kristin Roper, Nancy Hilton, Heidi Lombard, Allison Hester, Anne Chiavacci, Stephanie Meyers, Katherine McManus
BACKGROUND: Cancer anorexia-cachexia syndrome compromises physical function and nutritional and emotional well-being. Systematic screening followed by nutrition referral for appropriate interventions is rare.
. OBJECTIVES: The purpose of this study was to pilot a screening process followed by nutritional assessment and intervention when warranted for patients with lung malignancies.
. METHODS: Adult patients with lung malignancies were invited to complete the 12-item Anorexia/Cachexia Scale (A/CS-12) on the day of chemotherapy initiation in ambulatory infusion...
February 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29210648/vitamins-for-cancer-prevention-and-treatment-an-insight
#4
A Jain, A Tiwari, A Verma, S K Jain
Over a few decades a strong interlink between oxidative damage and cancer has been investigated by various scientists across the world on the basis of epidemiological observations of the effects of fruits and vegetables used in the diet for cancer patients. Primarily, Vitamin C, Vitamin D and Vitamin E are reported to be involved in the amelioration of side effects which occur in chemotherapy and radiation therapy of lungs, stomach, prostate, colorectal, gastric head and neck cancers. The vitamins acting as antioxidant adjuvants are found to have apoptotic and antiangiogenesis potential as well as inhibitory effects against metastasis in cancer cells...
2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/28723805/acute-pancreatitis-induced-by-etoposide-lobaplatin-combination-chemotherapy-used-for-the-treatment-of-lung-cancer-a-case-report-and-literature-review
#5
REVIEW
Cheng-Liang Cao, Peng-Yu Duan, Wang-Jun Zhang, Le Li, Feng-Zhi Qu, Bei Sun, Gang Wang
RATIONALE: Drug-induced pancreatitis (DIP) is a rare type of pancreatitis that is not usually observed in the clinical practice. It is generally difficult to distinguish from acute pancreatitis (AP) induced by other causes. PATIENT CONCERNS: Here, we report a 62-year-old Chinese female patient with "small cell lung cancer" as the initial presentation. Because the patient could not bear the surgical treatment, the chemotherapy composed of lobaplatin and etoposide was performed...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28721555/the-value-of-physical-performance-measurements-alongside-assessment-of-sarcopenia-in-predicting-receipt-and-completion-of-planned-treatment-in-non-small-cell-lung-cancer-an-observational-exploratory-study
#6
Jemima T Collins, Simon Noble, John Chester, Helen E Davies, William D Evans, Daniel Farewell, Jason F Lester, Diane Parry, Rebecca Pettit, Anthony Byrne
INTRODUCTION: The presence of muscle mass depletion is associated with poor outcomes and survival in cancer. Alongside muscle mass, assessment of muscle strength or physical performance is essential for the diagnosis of sarcopenia. Non-small cell lung cancer (NSCLC) is a prevalent form of cancer with high mortality, and Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) is commonly used to assess patients' suitability for treatment. However, a significant proportion of patients with good PS are unable to complete multidisciplinary team (MDT)-planned treatment...
January 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28671164/impact-of-chemotherapy-on-symptom-profile-oxidant-antioxidant-balance-and-nutritional-status-in-non-small-cell-lung-cancer
#7
Anant Mohan, Rosemary Poulose, Tarang Gupta, Kalpana Luthra, Ravindra M Pandey, Karan Madan, Vijay Hadda, Randeep Guleria
BACKGROUND: Lung cancer is associated with an oxidant-antioxidant imbalance that is implicated in tumor progression. However, the association of this imbalance on disease burden and treatment response is unclear. The effect of chemotherapy on oxidative stress, antioxidant status, and nutritional profile in patients with advanced nonsmall cell lung cancer (NSCLC) was prospectively evaluated. SUBJECTS AND METHODS: Patients with confirmed cytological/histological diagnosis of NSCLC were recruited...
July 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28614627/a-randomized-phase-ii-feasibility-trial-of-a-multimodal-intervention-for-the-management-of-cachexia-in-lung-and-pancreatic-cancer
#8
Tora S Solheim, Barry J A Laird, Trude Rakel Balstad, Guro B Stene, Asta Bye, Neil Johns, Caroline H Pettersen, Marie Fallon, Peter Fayers, Kenneth Fearon, Stein Kaasa
BACKGROUND: Cancer cachexia is a syndrome of weight loss (including muscle and fat), anorexia, and decreased physical function. It has been suggested that the optimal treatment for cachexia should be a multimodal intervention. The primary aim of this study was to examine the feasibility and safety of a multimodal intervention (n-3 polyunsaturated fatty acid nutritional supplements, exercise, and anti-inflammatory medication: celecoxib) for cancer cachexia in patients with incurable lung or pancreatic cancer, undergoing chemotherapy...
October 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28533161/differences-in-symptom-clusters-identified-using-ratings-of-symptom-occurrence-vs-severity-in-lung-cancer-patients-receiving-chemotherapy
#9
Melisa L Wong, Bruce A Cooper, Steven M Paul, Jon D Levine, Yvette P Conley, Fay Wright, Marilyn Hammer, Christine Miaskowski
CONTEXT: An important question in symptom clusters research is whether the number and types of symptom clusters vary based on the specific dimension of the symptom experience used to create the clusters. OBJECTIVES: Given that lung cancer patients undergoing chemotherapy (CTX) report an average of 14 co-occurring symptoms and studies of symptom clusters in these patients are limited, the purpose of this study, in lung cancer patients undergoing CTX (n = 145), was to identify whether the number and types of symptom clusters differed based on whether symptom occurrence rates or symptom severity ratings were used to create the clusters...
August 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28244415/a-randomized-phase-2-trial-of-prophylactic-manuka-honey-for-the-reduction-of-chemoradiation-therapy-induced-esophagitis-during-the-treatment-of-lung-cancer-results-of-nrg-oncology-rtog-1012
#10
RANDOMIZED CONTROLLED TRIAL
Shannon E Fogh, Snehal Deshmukh, Lawrence B Berk, Amylou C Dueck, Kevin Roof, Sherif Yacoub, Thomas Gergel, Kevin Stephans, Andreas Rimner, Albert DeNittis, John Pablo, Justin Rineer, Terence M Williams, Deborah Bruner
PURPOSE: Randomized trials have shown that honey is effective for the prevention of radiation-induced mucositis in head and neck cancer patients. Because there is no efficacious preventative for radiation esophagitis in lung cancer patients, this trial compared liquid honey, honey lozenges, and standard supportive care for radiation esophagitis. METHODS: The patients were stratified by percentage of esophagus receiving specific radiation dose (V60 Gy esophagus <30% or ≥30%) and were then randomized between supportive care, 10 mL of liquid manuka honey 4 times a day, and 2 lozenges (10 mL of dehydrated manuka honey) 4 times a day during concurrent chemotherapy and radiation therapy...
March 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28219213/-clinical-application-value-of-prognostic-nutritional-index-for-predicting-survival-in-patients-with-advanced-non-small-cell-lung-cancer
#11
W J Xu, Y M Kang, L Zhou, F F Chen, Y H Song, C Q Zhang
Objective: To explore the clinical application value of prognostic nutritional index(PNI) for predicting overall survival(OS) in patients with advanced non-small cell lung cancer (NSCLC). Methods: 123 patients with histologically confirmed non-small cell lung cancer were enrolled in this study, and their clinical and laboratory data were reviewed. The PNI was calculated as 10×serum albumin value+ 5×total lymphocyte countin peripheral blood.Univariate and multivariate analyses were used to identify the potential prognostic factors for advanced NSCLC...
February 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28156492/food-as-medicine-a-randomized-controlled-trial-rct-of-home-delivered-medically-tailored-meals-hdmtm-on-quality-of-life-qol-in-metastatic-lung-and-non-colorectal-gi-cancer-patients
#12
Raymond Mailhot Vega, Lisa Zullig, Alissa Wassung, Dorella Walters, Noah Berland, Kevin Lee Du, Jiyoung Ahn, Cynthia G Leichman, Deirdre Jill Cohen, Ping Gu, Abraham Chachoua, Lawrence P Leichman, Karen Pearl, Peter B Schiff
155 Background: Malnutrition incidence in cancer approaches 85%, disproportionately burdening those with lung, GI, and advanced stage cancers. Malnourished patients have impaired chemotherapy response, shorter survival, longer hospital stays, and decreased QoL. Home delivered meals are nutritional interventions that improve patient well-being, nutrition, and lower healthcare costs in the elderly but have not been studied as an intervention in cancer patients. HDMTM are nutritionist prescribed home delivered meals tailored to patient's symptoms, co-morbidities, and health needs...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28133202/-cr-of-all-target-lesions-in-a-patient-with-metastatic-esophageal-cancer-and-generalized-weakness-treated-with-systemic-chemotherapy-after-nutritional-support
#13
Shigeru Fujisaki, Motoi Takashina, Ryouichi Tomita, Kenichi Sakurai, Tadatoshi Takayama
We report here a case of CR of all target lesions in a patient with esophageal cancer with multiple metastases treated with systemic chemotherapy after nutritionalsupport. A 75-year-old man was referred to our hospital with a diagnosis of multiple- metastatic esophagealcancer in June 2014. He showed generalized weakness with poor dietary intake, and he was initially admitted for nutritional support by parenteral nutrition. Biopsy specimens revealed mixed squamous- and adenocarcinoma: MtLtUtAeG, 13 cm, type 2, cT3, IM1-St, cN3, cM1(liver, lungs, and stomach), cStage IV b esophagealcarcinoma...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28107410/prognostic-impact-of-ct-quantified-muscle-and-fat-distribution-before-and-after-first-line-chemotherapy-in-lung-cancer-patients
#14
Johanna Nattenmüller, Raoul Wochner, Thomas Muley, Martin Steins, Simone Hummler, Birgit Teucher, Joachim Wiskemann, Hans-Ulrich Kauczor, Mark Oliver Wielpütz, Claus Peter Heussel
INTRODUCTION: Cachexia and sarcopenia are associated with poor outcome and increased chemotherapy-induced toxicity in lung cancer patients. However, the complex interplay of obesity, sarcopenia and cachexia, and its impact on survival in the context of first-line-chemotherapy is not yet understood. METHODS: In 200 consecutively recruited lung cancer patients (70 female, mean age 62y; mean BMI 25 kg/m2; median follow-up 15.97 months) with routine staging-CT before and after chemotherapy (CTX, mean interval: 4...
2017: PloS One
https://www.readbyqxmd.com/read/28104436/capsaicin-synergizes-with-camptothecin-to-induce-increased-apoptosis-in-human-small-cell-lung-cancers-via-the-calpain-pathway
#15
Jamie R Friedman, Haley E Perry, Kathleen C Brown, Ying Gao, Ju Lin, Cathyrn D Stevenson, John D Hurley, Nicholas A Nolan, Austin T Akers, Yi Charlie Chen, Krista L Denning, Linda G Brown, Piyali Dasgupta
Small cell lung cancer (SCLC) is characterized by excellent initial response to chemotherapy and radiation therapy with a majority of the patients showing tumor shrinkage and even remission. However, the challenge with SCLC therapy is that patients inevitably relapse and subsequently do not respond to the first line treatment. Recent clinical studies have investigated the possibility of camptothecin-based combination therapy as first line treatment for SCLC patients. Conventionally, camptothecin is used for recurrent SCLC and has poor survival outcomes...
April 1, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/27635765/practical-multimodal-care-for-cancer-cachexia
#16
REVIEW
Matthew Maddocks, Jane Hopkinson, John Conibear, Annie Reeves, Clare Shaw, Ken C H Fearon
PURPOSE OF REVIEW: Cancer cachexia is common and reduces function, treatment tolerability and quality of life. Given its multifaceted pathophysiology a multimodal approach to cachexia management is advocated for, but can be difficult to realise in practice. We use a case-based approach to highlight practical approaches to the multimodal management of cachexia for patients across the cancer trajectory. RECENT FINDINGS: Four cases with lung cancer spanning surgical resection, radical chemoradiotherapy, palliative chemotherapy and no anticancer treatment are presented...
December 2016: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27565917/quality-of-life-symptom-status-and-physical-performance-in-patients-with-advanced-non-small-cell-lung-cancer-undergoing-chemotherapy-an-exploratory-analysis-of-secondary-data
#17
Shirin M Shallwani, Maureen J Simmonds, Goulnar Kasymjanova, Jadranka Spahija
OBJECTIVES: Our objectives were: (a) to identify predictors of change in health-related quality of life (HRQOL) in patients with advanced non-small cell lung cancer (NSCLC) undergoing chemotherapy; and (b) to characterize symptom status, nutritional status, physical performance and HRQOL in this population and to estimate the extent to which these variables change following two cycles of chemotherapy. METHODS: A secondary analysis of a longitudinal observational study of 47 patients (24 men and 23 women) with newly diagnosed advanced NSCLC receiving two cycles of first-line chemotherapy was performed...
September 2016: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/27493875/salidroside-alleviates-cachexia-symptoms-in-mouse-models-of-cancer-cachexia-via-activating-mtor-signalling
#18
Xiangzheng Chen, Yangping Wu, Tinghan Yang, Mingtian Wei, Yuxi Wang, Xiangbing Deng, Congcong Shen, Wenting Li, Hang Zhang, Weiyong Xu, Lantu Gou, Yong Zeng, Yonghui Zhang, Ziqiang Wang, Jinliang Yang
BACKGROUND: Cachexia has a devastating impact on survival and quality of life for many cancer patients and contributes to nearly one-third of all cancer deaths; also, it is associated with poor responses to chemotherapy and survival. A better understanding of the underlying mechanisms of cancer-associated cachexia (CAC), coupled with effective therapeutic approaches, will improve management of progressive functional impairment in cancer patients. Salidroside, a phenylpropanoid glycoside in Rhodiola rosea L, has been reported to possess potential anti-fatigue, anti-ageing, and anti-Alzheimer's disease properties...
May 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27017943/nutritional-status-in-the-era-of-target-therapy-poor-nutrition-is-a-prognostic-factor-in-non-small-cell-lung-cancer-with-activating-epidermal-growth-factor-receptor-mutations
#19
Sehhoon Park, Seongyeol Park, Se-Hoon Lee, Beomseok Suh, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Young Whan Kim, Dae Seog Heo
BACKGROUND/AIMS: Pretreatment nutritional status is an important prognostic factor in patients treated with conventional cytotoxic chemotherapy. In the era of target therapies, its value is overlooked and has not been investigated. The aim of our study is to evaluate the value of nutritional status in targeted therapy. METHODS: A total of 2012 patients with non-small cell lung cancer (NSCLC) were reviewed and 630 patients with activating epidermal growth factor receptor (EGFR) mutation treated with EGFR tyrosine kinase inhibitor (TKI) were enrolled for the final analysis...
November 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/26943275/value-changes-in-the-detection-and-recognition-thresholds-of-three-basic-tastes-in-lung-cancer-patients-receiving-cisplatin-and-paclitaxel-and-its-association-with-nutritional-and-quality-of-life-parameters
#20
Jenny G Turcott, Eva Juárez-Hernández, Martha De la Torre-Vallejo, Karla Sánchez-Lara, Julissa Luvian-Morales, Oscar Arrieta
We evaluated the effects of cisplatin and paclitaxel on taste acuity and their associations with nutritional and health-related quality of life (HRQL) in patients with advanced non-small-cell lung cancer (NSCLC). Forty chemotherapy (CT)-naïve patients were assessed at baseline and after two cycles of paclitaxel and cisplatin. The taste evaluation was performed using a rinsing technique to identify detection and recognition thresholds (DT and RT) of bitter, sweet, and umami tastes. At baseline, 37.5% of the patients reported dysgeusia...
2016: Nutrition and Cancer
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