keyword
MENU ▼
Read by QxMD icon Read
search

Leprosy

keyword
https://www.readbyqxmd.com/read/28515998/dermoscopy-of-histoid-leprosy-a-case-report
#1
Balachandra S Ankad, Punit S Sakhare
No abstract text is available yet for this article.
April 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28514659/the-intergenic-recombinant-hla-b%C3%A2-46-01-has-a-distinctive-peptidome-that-includes-kir2dl3-ligands
#2
Hugo G Hilton, Curtis P McMurtrey, Alex S Han, Zakia Djaoud, Lisbeth A Guethlein, Jeroen H Blokhuis, Jason L Pugh, Ana Goyos, Amir Horowitz, Rico Buchli, Ken W Jackson, Wilfred Bardet, David A Bushnell, Philip J Robinson, Juan L Mendoza, Michael E Birnbaum, Morten Nielsen, K Christopher Garcia, William H Hildebrand, Peter Parham
HLA-B(∗)46:01 was formed by an intergenic mini-conversion, between HLA-B(∗)15:01 and HLA-C(∗)01:02, in Southeast Asia during the last 50,000 years, and it has since become the most common HLA-B allele in the region. A functional effect of the mini-conversion was introduction of the C1 epitope into HLA-B(∗)46:01, making it an exceptional HLA-B allotype that is recognized by the C1-specific natural killer (NK) cell receptor KIR2DL3. High-resolution mass spectrometry showed that HLA-B(∗)46:01 has a low-diversity peptidome that is distinct from those of its parents...
May 16, 2017: Cell Reports
https://www.readbyqxmd.com/read/28511777/expression-of-interleukin-1%C3%AE-and-interleukin-6-in-leprosy-reactions-in-patients-with-human-immunodeficiency-virus-coinfection
#3
Carla Andréa Avelar Pires, Juarez Antônio Simões Quaresma, Tinara Leila de Souza Aarão, Jorge Rodrigues de Souza, Geraldo Mariano Moraes Macedo, Fernando Octávio Machado Jucá Neto, Marília Brasil Xavier
Previous studies suggest that coinfection of leprosy and human immunodeficiency virus (HIV) does not decrease the frequency and intensity of leprosy reactions. However, the immunological aspects of leprosy reactions in coinfected patients remain obscure, with a limited number of studies showing contradictory results. Observational study using tissue samples collected during leprosy reactions from 15 patients coinfected with leprosy and HIV and from 15 patients with leprosy alone. Patients were part of a prior larger cohort study of leprosy patients with and without HIV coinfection...
May 13, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28505186/in-situ-complement-activation-and-t-cell-immunity-in-leprosy-spectrum-an-immunohistological-study-on-leprosy-lesional-skin
#4
Nawal Bahia El Idrissi, Anand M Iyer, Valeria Ramaglia, Patricia S Rosa, Cleverson T Soares, Frank Baas, Pranab K Das
Mycobacterium leprae (M. leprae) infection causes nerve damage and the condition worsens often during and long after treatment. Clearance of bacterial antigens including lipoarabinomannan (LAM) during and after treatment in leprosy patients is slow. We previously demonstrated that M. leprae LAM damages peripheral nerves by in situ generation of the membrane attack complex (MAC). Investigating the role of complement activation in skin lesions of leprosy patients might provide insight into the dynamics of in situ immune reactivity and the destructive pathology of M...
2017: PloS One
https://www.readbyqxmd.com/read/28496303/development-of-a-potent-invigorator-of-immune-responses-endowed-with-both-preventive-and-therapeutic-properties
#5
REVIEW
Gursaran P Talwar, Jagdish C Gupta, Abu S Mustafa, Hemanta K Kar, Kiran Katoch, Shreemanta K Parida, Prabhakara P Reddi, Niyaz Ahmed, Vikram Saini, Somesh Gupta
This article reviews briefly the making of an immunoprophylactic-cum-immunotherapeutic vaccine against leprosy. The vaccine is based on cultivable, heat-killed atypical mycobacteria, whose gene sequence is now known. It has been named Mycobacterium indicus pranii. It has received the approval of the Drug Controller General of India and the US Food and Drug Administration. Besides leprosy, M. indicus pranii has found utility in the treatment of category II ("difficult to treat") tuberculosis. It also heals ugly anogenital warts...
2017: Biologics: Targets & Therapy
https://www.readbyqxmd.com/read/28492023/leprosy-and-women
#6
REVIEW
Rashmi Sarkar, Swetalina Pradhan
Leprosy has an impact on the physical, social, and psychological health of affected people. Women in developing countries seek health care late for any health-related issues. Leprosy, a disease known for its stigma, adds further to these facts. Also, close contact between women and family members, especially children, increases the chance of transmission to others and thereby increases the disease burden in the society. Hence, leprosy in women is an important issue for the affected patient, their family members, and society as a whole...
December 2016: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28492018/impact-of-leishmaniasis-in-women-a-practical-review-with-an-update-on-my-isd-supported-initiative-to-combat-leishmaniasis-in-yemen-elyp
#7
REVIEW
Mohamed A Al-Kamel
Stigma is synonymous with leishmaniasis, an endemic deadly flesh-eating disease in Yemen that affects predominantly poor rural women and children. Women with leishmaniasis often present late and experience not only physical deformities and the risk of death, but also the painful stigma of the disease and its consequences, a similar situation to that of leprosy decades ago. The International Society of Dermatology-sponsored community dermatology project Eradication of Leishmaniasis from Yemen Project has made a difference in the leishmaniasis situation in Yemen and addressed its magnitude...
September 2016: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28489144/modified-simple-decompression-in-the-treatment-of-cubital-tunnel-syndrome-avoiding-ulnar-nerve-subluxation
#8
Marcus André Acioly, Amanda Mendes Soares, Mariana Lopes de Almeida, Renata Barbosa, Egon Daxbacher, Carlos Henrique Carvalho
Objective: In this study, we propose a modification to the simple decompression technique that contains the ulnar nerve in the cubital fossa, thus preventing subluxation during forearm flexion movements. Methods: Five consecutive patients with leprosy-associated cubital tunnel syndrome underwent surgery with the modified technique between July 2011 and October 2012. Results: The most common symptoms were neuropathic pain and sensory changes (both 60%)...
April 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28486035/an-employee-with-undiagnosed-leprosy-are-other-employees-at-risk
#9
Ann R Lurati
MJ is a janitor working in an office building for the past 5 years. He sustained a third-degree burn with a secondary infection and was sent to the county hospital. He was diagnosed with leprosy. The employees in the office building were concerned with the risk of transmission. This article reviews leprosy, and implications for occupational health nurses are discussed.
May 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28472183/global-practices-in-regard-to-implementation-of-preventive-measures-for-leprosy
#10
Laura Gillini, Erwin Cooreman, Tanya Wood, Venkata Rao Pemmaraju, Paul Saunderson
No abstract text is available yet for this article.
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28470151/a-medical-enigma%C3%A2-what-gale-chinoise-chinese-scabies-meant%C3%A2-150-years-ago
#11
B-A Gaüzere, P Aubry
CONTEXT: The meaning of the term "gale chinoise" mentioned in some articles about French overseas territories in the 19th century, remains unclear. In response to a query of an American colleague dermatologist trying to find out what it meant 150 years ago, we attempted to elucidate the nature of this ancient disease, which today would be translated literally as Chinese scabies. METHOD: We submitted the query to a panel of civilian and military French tropical medicine specialists including dermatologists, through two networks : Association Amicale Santé Navale et d'Outre-Mer and Société de Pathologie Exotique...
May 4, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28467415/interruption-of-persistent-exposure-to-leprosy-combined-or-not-with-recent-bcg-vaccination-enhances-the-response-to-mycobacterium-leprae-specific-antigens
#12
Fernanda Marques de Carvalho, Luciana Silva Rodrigues, Nádia Cristina Duppre, Iris Maria Peixoto Alvim, Marcelo Ribeiro-Alves, Roberta Olmo Pinheiro, Euzenir Nunes Sarno, Maria Cristina Vidal Pessolani, Geraldo Moura Batista Pereira
Household contacts of multibacillary leprosy patients (HCMB) constitute the group of individuals at the highest risk of developing leprosy. Early diagnosis and treatment of their index cases combined with Bacille Calmette-Guerin (BCG) immunization remain important strategies adopted in Brazil to prevent HCMB from evolving into active disease. In the present study, we assessed the impact of these measures on the immune response to Mycobacterium leprae in HCMB. Peripheral blood mononuclear cells (PBMC) from HCMB (n = 16) were obtained at the beginning of leprosy index case treatment (T0)...
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28457830/prevalence-and-risk-factors-for-hepatitis-b-and-c-viruses-in-patients-with-leprosy
#13
J E F Costa, V M S Morais, J P Gonçales, D M Silva, M R C D Coêlho
It has been reported a higher seroprevalence of HBV and HCV in leprosy patients than in the general population, but the reasons for these findings are not yet clear. On the other hand, there is evidence that these viruses may influence the onset of leprosy reactional episodes, an important cause of neurological sequelae. This study aimed to determine seroprevalence and risk factors for HBV and HCV in leprosy patients and to investigate its association with leprosy reactions. Patients attended from 2015 to 2016 at a Reference Center in Leprosy in Northeastern region of Brazil, were interviewed, had their records reviewed to investigate biological, clinical, behavioral and socioeconomic factors, and underwent blood sample collection...
April 28, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28457229/correlation-between-therapy-and-lipid-profile-of-leprosy-patients-is-there-a-higher-risk-for-developing-cardiovascular-diseases-after-treatment
#14
Rosalba V G Silva, Rafael S de Araújo, Tinara L S Aarão, Paulo Diovanne da Silva Costa, Jorge R Sousa, Juarez A S Quaresma
BACKGROUND: The impact of leprosy reduces health-related quality of life of affected patients, interfering with different factors such as nutrition. This study investigated the lipid profile, nutritional status, and risk for cardiovascular disease (CVD) in patients who underwent leprosy treatment in Brazil. METHODS: Eighty-four adult patients of both genders ranging in age from 20 to 60 years and diagnosed with paucibacillary (PB) or multibacillary (MB) leprosy were selected after undergoing multidrug treatment...
May 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28444521/leprosy-in-children
#15
REVIEW
Josafá Gonçalves Barreto, Marco Andrey Cipriani Frade, Fred Bernardes Filho, Moises Batista da Silva, John Stewart Spencer, Claudio Guedes Salgado
PURPOSE OF REVIEW: This manuscript aims to review the cutting-edge developments regarding to the diagnosis, management, and prevention of leprosy in children. RECENT FINDINGS: Leprosy transmission still occurs continuously in some endemic areas in the world. Leprosy in children below 15 years old is a robust indicator of active source of infection in the community where they live. A special focus on children to reduce disabilities and reduce transmission is one of the core areas of interventions of the global leprosy strategy 2016-2020...
June 2017: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/28442804/clinico-epidemiological-profile-of-patients-attending-suraksha-clinic-of-tertiary-care-hospital-of-north-india
#16
H S Banger, Anisha Sethi, Sita Malhotra, Suresh Kumar Malhotra, Tejinder Kaur
BACKGROUND: Sexually transmitted infections (STIs) are a global health problem. Trends of STIs vary from place to place depending on various epidemiological factors prevailing in that respective geographic area. AIMS AND OBJECTIVES: The present study was conducted to find the pattern and prevalence of different STIs out of total STI clinic attendees, to identify any change in the trend of STIs, various epidemiological factors, and behavior of individual diseases...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28438129/severe-type-1-upgrading-leprosy-reaction-in-a-renal-transplant-recipient-a-paradoxical-manifestation-associated-with-deficiency-of-antigen-specific-regulatory-t-cells
#17
Ana Paula Vieira, Maria Angela Bianconcini Trindade, Flávio Jota de Paula, Neusa Yurico Sakai-Valente, Alberto José da Silva Duarte, Francine Brambate Carvalhinho Lemos, Gil Benard
BACKGROUND: Due to its chronic subclinical course and large spectrum of manifestations, leprosy often represents a diagnostic challenge. Even with proper anti-mycobacteria treatment, leprosy follow up remains challenging: almost half of leprosy patients may develop reaction episodes. Leprosy is an infrequent complication of solid organ transplant recipients. This case report illustrates the challenges in diagnosing and managing leprosy and its reactional states in a transplant recipient...
April 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28438086/feline-leprosy-due-to-candidatus-mycobacterium-tarwinense
#18
Carolyn R O'Brien, Richard Malik, Maria Globan, George Reppas, Christina McCowan, Janet A Fyfe
OBJECTIVES: This paper, the first in a series of three on 'feline leprosy', provides a detailed description of disease referable to Candidatus 'Mycobacterium tarwinense', the most common cause of feline leprosy in Victoria, Australia. METHODS: Cases were sourced retrospectively and prospectively for this observational study, describing clinical, geographical and molecular microbiological data for cats definitively diagnosed with Candidatus 'M tarwinense' infection...
May 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28438084/history-and-mysteries-of-leprosy
#19
Carolyn O'Brien, Richard Malik
No abstract text is available yet for this article.
May 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28436433/pathways-and-genes-associated-with-immune-dysfunction-in-sheep-paratuberculosis
#20
Anton Gossner, Craig Watkins, Francesca Chianini, John Hopkins
Multibacillary and paucibacillary paratuberculosis are both caused by Mycobacterium avium subspecies paratuberculosis. Multibacillary lesions are composed largely of infected epithelioid macrophages and paucibacillary lesions contain T cells but few bacteria. Multibacillary disease is similar to human lepromatous leprosy, with variable/high levels of antibody and a dysfunctional immune response. Animals with paucibacillary disease have high cell-mediated immunity and variable levels of antibody. This study aims to characterize the immunological dysfunction using TruSeq analysis of the ileocaecal lymph node that drains disease lesions...
April 24, 2017: Scientific Reports
keyword
keyword
7330
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"