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Selective mutism

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https://www.readbyqxmd.com/read/27830922/pediatric-selective-mutism-therapy-a-randomized-controlled-trial
#1
Maria Esposito, Francesca Gimigliano, Maria R Barillari, Francesco Precenzano, Maria Ruberto, Joseph Sepe, Umberto Barillari, Raffaele Gimigliano, Roberto Militerni, Giovanni Messina, Marco Carotenuto
BACKGROUND: Selective Mutism (SM) is a rare disease in children coded by DSM-5 as an anxiety disorder. Despite the disabling nature of the disease, there is still no specific treatment. AIMS: The aims of this study were to verify the efficacy of six-month standard psychomotor treatment and the positive changes in lifestyle, in a population of children affected by SM. DESIGN: Randomised Controlled Trial registered in the European Clinical Trials Registry (EuDract 2015-001161-36)...
November 10, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27802104/a-comparative-study-of-sociability-in-angelman-cornelia-de-lange-fragile-x-down-and-rubinstein-taybi-syndromes-and-autism-spectrum-disorder
#2
Joanna Moss, Lisa Nelson, Laurie Powis, Jane Waite, Caroline Richards, Chris Oliver
Few comparative studies have evaluated the heterogeneity of sociability across a range of neurodevelopmental disorders. The Sociability Questionnaire for People with Intellectual Disability (SQID) was completed by caregivers of individuals with Cornelia de Lange (n = 98), Angelman (n = 66), Fragile X (n = 142), Down (n = 117) and Rubinstein Taybi (n = 88) syndromes and autism spectrum disorder (ASD; n = 107). Between groups and age-band (<12yrs; 12-18yrs; >18yrs) comparisons of SQID scores were conducted...
November 2016: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/27626066/a-novel-de-novo-mutation-in-atp1a3-and-childhood-onset-schizophrenia
#3
Niklas Smedemark-Margulies, Catherine A Brownstein, Sigella Vargas, Sahil K Tembulkar, Meghan C Towne, Jiahai Shi, Elisa Gonzalez-Cuevas, Kevin X Liu, Kaya Bilguvar, Robin J Kleiman, Min-Joon Han, Alcy Torres, Gerard T Berry, Timothy W Yu, Alan H Beggs, Pankaj B Agrawal, Joseph Gonzalez-Heydrich
We describe a child with onset of command auditory hallucinations and behavioral regression at 6 yr of age in the context of longer standing selective mutism, aggression, and mild motor delays. His genetic evaluation included chromosomal microarray analysis and whole-exome sequencing. Sequencing revealed a previously unreported heterozygous de novo mutation c.385G>A in ATP1A3, predicted to result in a p.V129M amino acid change. This gene codes for a neuron-specific isoform of the catalytic α-subunit of the ATP-dependent transmembrane sodium-potassium pump...
September 2016: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/27617154/the-7q11-23-microduplication-syndrome-a-clinical-report-with-review-of-literature
#4
REVIEW
Elham Abbas, Devin M Cox, Teri Smith, Merlin G Butler
We report a 14-year-old adolescent girl with selective mutism (SM) and a 7q11.23 microduplication detected by chromosomal microarray (CMA) analysis and reviewed the literature from 18 published clinical reports. Our patient had specific phobias, SM, extreme anxiety, obesity, cutis marmorata, and a round appearing face with a short neck and over folded ears. We reviewed the published clinical, cognitive, behavioral, and cytogenetic findings grouped by speech and language delay, growth and development, craniofacial, clinical, and behavior and cognitive features due to the 7q11...
September 2016: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/27468379/identifying-treatment-response-of-sertraline-in-a-teenager-with-selective-mutism-using-electrophysiological-neuroimaging
#5
Andy R Eugene, Jolanta Masiak
BACKGROUND: Selective Mutism is described as the inability to verbally express oneself in anxiety provoking social situations and may result in awkward social interactions in school-aged children. In this case-report we present the baseline electrophysiological neuroimaging results and after treatment with Sertraline for 6-weeks. METHODS: A 20-channel EEG event-related potential recording was acquired during an internal voice task at baseline prior to the initiation of 50mg of Sertraline and then repeated 6-weeks after treatment with Sertraline...
June 2016: International Journal of Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27349358/anxiety
#6
Michelle G Craske, Murray B Stein
Anxiety disorders (separation anxiety disorder, selective mutism, specific phobias, social anxiety disorder, panic disorder, agoraphobia, and generalised anxiety disorder) are common and disabling conditions that mostly begin during childhood, adolescence, and early adulthood. They differ from developmentally normative or stress-induced transient anxiety by being marked (ie, out of proportion to the actual threat present) and persistent, and by impairing daily functioning. Most anxiety disorders affect almost twice as many women as men...
June 24, 2016: Lancet
https://www.readbyqxmd.com/read/27179521/the-youth-anxiety-measure-for-dsm-5-yam-5-development-and-first-psychometric-evidence-of-a-new-scale-for-assessing-anxiety-disorders-symptoms-of-children-and-adolescents
#7
Peter Muris, Ellin Simon, Hester Lijphart, Arjan Bos, William Hale, Kelly Schmeitz
The Youth Anxiety Measure for DSM-5 (YAM-5) is a new self- and parent-report questionnaire to assess anxiety disorder symptoms in children and adolescents in terms of the contemporary classification system. International panels of childhood anxiety researchers and clinicians were used to construct a scale consisting of two parts: part one consists of 28 items and measures the major anxiety disorders including separation anxiety disorder, selective mutism, social anxiety disorder, panic disorder, and generalized anxiety disorder, whereas part two contains 22 items that focus on specific phobias and (given its overlap with situational phobias) agoraphobia...
May 14, 2016: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/27089281/selective-mutism-the-fraternal-twin-of-childhood-social-phobia
#8
Angelika Gensthaler, Verena Maichrowitz, Michael Kaess, Marc Ligges, Christine M Freitag, Christina Schwenck
BACKGROUND: Selective mutism (SM) is an anxiety disorder with a close link to childhood social phobia (SP). Our studies compare behavioral problem profiles in children and adolescents with SM and SP and control groups and assess the comorbidity patterns of SM and SP. METHODS: Participants aged 3-18 years with SM (n = 95), SP (n = 74) and internalizing disorders (INT, n = 46) and a typically developing control group (CG, n = 119) were assessed with the Child Behavior Checklist (CBCL); adolescents were additionally assessed with the Youth Self-Report (YSR)...
2016: Psychopathology
https://www.readbyqxmd.com/read/26970743/selective-mutism-and-temperament-the-silence-and-behavioral-inhibition-to-the-unfamiliar
#9
Angelika Gensthaler, Sally Khalaf, Marc Ligges, Michael Kaess, Christine M Freitag, Christina Schwenck
Behavioral inhibition (BI) is a suspected precursor of selective mutism. However, investigations on early behavioral inhibition of children with selective mutism are lacking. Children aged 3-18 with lifetime selective mutism (n = 109), social phobia (n = 61), internalizing behavior (n = 46) and healthy controls (n = 118) were assessed using the parent-rated Retrospective Infant Behavioral Inhibition (RIBI) questionnaire. Analyses showed that children with lifetime selective mutism and social phobia were more inhibited as infants and toddlers than children of the internalizing and healthy control groups, who displayed similar low levels of behavioral inhibition...
October 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/26940121/social-communication-anxiety-treatment-s-cat-for-children-and-families-with-selective-mutism-a-pilot-study
#10
Evelyn R Klein, Sharon Lee Armstrong, Kathryn Skira, Janice Gordon
This research assessed the feasibility of Social Communication Anxiety Treatment (S-CAT) developed by Elisa Shipon-Blum, a brief multimodal approach, to increase social communication in 40 children aged 5-12 years with selective mutism (SM). SM is a disorder in which children consistently fail to speak in specific situations although they have the ability to do so. Key features of this approach are the SM-Social Communication Comfort Scale (SCCS), transfer of control (ToC), a nonchalant therapeutic style, and cognitive-behavioral strategies over a brief time frame...
March 2, 2016: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/26849811/magnetic-resonance-guided-laser-interstitial-thermal-therapy-report-of-a-series-of-pediatric-brain-tumors
#11
Zulma Tovar-Spinoza, Hoon Choi
OBJECTIVE Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) is a novel, minimally invasive treatment that has multiple advantages in pediatric use and broad applicability for different types of lesions. Here, the authors report the preliminary results of the first series of pediatric brain tumors treated with MRgLITT at Golisano Children's Hospital in Syracuse, New York. METHODS Pediatric brain tumors treated with MRgLITT between February 2012 and August 2014 at Golisano Children's Hospital were evaluated retrospectively...
June 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/26835496/identifying-quantitative-imaging-features-of-posterior-fossa-syndrome-in-longitudinal-mri
#12
Michaela Spiteri, David Windridge, Shivaram Avula, Ram Kumar, Emma Lewis
Up to 25% of children who undergo brain tumor resection surgery in the posterior fossa develop posterior fossa syndrome (PFS). This syndrome is characterized by mutism and disturbance in speech. Our hypothesis is that there is a correlation between PFS and the occurrence of hypertrophic olivary degeneration (HOD) in structures within the posterior fossa, known as the inferior olivary nuclei (ION). HOD is exhibited as an increase in size and intensity of the ION on an MR image. Longitudinal MRI datasets of 28 patients were acquired consisting of pre-, intra-, and postoperative scans...
October 2015: Journal of Medical Imaging
https://www.readbyqxmd.com/read/26710961/catatonia-in-ugandan-children-with-nodding-syndrome-and-effects-of-treatment-with-lorazepam-a-pilot-study
#13
Angelina Kakooza-Mwesige, Dirk M Dhossche, Richard Idro, Dickens Akena, Joyce Nalugya, Benard T Opar
BACKGROUND: Nodding syndrome (NS) is a severe neuropsychiatric syndrome of an unknown etiology affecting children and adolescents mostly in Eastern Africa. Symptoms of NS and catatonia seem to overlap. We investigated the presence and types of catatonic symptoms in NS and their response to one or two doses of lorazepam, the first-line treatment for catatonia. METHODS: A cross-sectional descriptive study with systematic assessment of catatonia in 33 patients with NS using a modified version of the Bush Francis Catatonia Rating Scale...
December 28, 2015: BMC Research Notes
https://www.readbyqxmd.com/read/26709680/selective-mutism
#14
REVIEW
Alexandra Hua, Nili Major
PURPOSE OF REVIEW: Selective mutism is a disorder in which an individual fails to speak in certain social situations though speaks normally in other settings. Most commonly, this disorder initially manifests when children fail to speak in school. Selective mutism results in significant social and academic impairment in those affected by it. This review will summarize the current understanding of selective mutism with regard to diagnosis, epidemiology, cause, prognosis, and treatment. RECENT FINDINGS: Studies over the past 20 years have consistently demonstrated a strong relationship between selective mutism and anxiety, most notably social phobia...
February 2016: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/26625009/anxiety-and-oppositional-behavior-profiles-among-youth-with-selective-mutism
#15
Rachele A Diliberto, Christopher A Kearney
UNLABELLED: Selective mutism (SM) is a debilitating condition in which a child does not speak in social situations where speech is expected. The clinical conceptualization of SM has been debated historically, with evidence pointing partly to anxious and oppositional behavior profiles. Behavioral characteristics were examined in a clinical sample of 57 youth formally diagnosed with selective mutism. Parents rated children across internalizing and externalizing behaviors on the Child Behavior Checklist...
January 2016: Journal of Communication Disorders
https://www.readbyqxmd.com/read/26560144/the-use-of-medication-in-selective-mutism-a-systematic-review
#16
REVIEW
Katharina Manassis, Beate Oerbeck, Kristin Romvig Overgaard
Despite limited evidence, selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs) are used to reduce symptoms of selective mutism (SM) in children unresponsive to psychosocial interventions. We review existing evidence for the efficacy of these medications, limitations of the literature, and resulting treatment considerations. Bibliographic searches were conducted in Medline, Embase, PsycInfo, Web of Science and Cochrane up to June 2015. Two reviewers independently sought studies of children with SM as primary psychiatric diagnosis, which reported response to medication treatment...
June 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/26508972/a-selective-mutism-arising-from-first-language-attrition-successfully-treated-with-paroxetine-cbt-combination-treatment
#17
Agostino Serra, Paola Di Mauro, Claudio Andaloro, Luigi Maiolino, Piero Pavone, Salvatore Cocuzza
After immersion in a foreign language, speakers often have difficulty retrieving native-language words and may experience a decrease in its proficiency, this phenomenon, in the non-pathological form, is known as first language attrition. Self-perception of this low native-language proficiency and apprehension occurring when speaking is expected and, may sometimes lead these people to a state of social anxiety and, in extreme forms, can involve the withholding of speech as a primitive tool for self-protection, linking them to selective mutism...
October 2015: Psychiatry Investigation
https://www.readbyqxmd.com/read/26092264/ties-of-silence-family-lived-experience-of-selective-mutism-in-identical-twins
#18
Vårin Albrigtsen, Benedicte Eskeland, Magne Mæhle
This article is based on an in-depth interview with a pair of twins diagnosed with selective mutism and their parents 2 years after recovery. Selective mutism (SM) is a rare disorder, and identical twins sharing the condition are extremely rare. The twins developed SM simultaneously during their first year of school. The treatment and follow-up they received for several years are briefly described in this article. The interview explored the children's and their parents' narratives about the origin of the condition, the challenges it entailed in their daily lives, and what they found helpful in the treatment they were offered...
April 2016: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/25900101/children-with-7q11-23-duplication-syndrome-psychological-characteristics
#19
Carolyn B Mervis, Bonita P Klein-Tasman, Myra J Huffman, Shelley L Velleman, C Holley Pitts, Danielle R Henderson, Janet Woodruff-Borden, Colleen A Morris, Lucy R Osborne
To begin to delineate the psychological characteristics associated with classic 7q11.23 duplication syndrome (duplication of the classic Williams syndrome region; hereafter classic Dup7), we tested 63 children with classic Dup7 aged 4-17 years. Sixteen toddlers aged 18-45 months with classic Dup7 and 12 adults identified by cascade testing also were assessed. For the child group, median General Conceptual Ability (similar to IQ) on the Differential Ability Scales-II was 85.0 (low average), with a range from severe disability to high average ability...
July 2015: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/25842046/children-of-few-words-relations-among-selective-mutism-behavioral-inhibition-and-social-anxiety-symptoms-in-3-to-6-year-olds
#20
Peter Muris, Eline Hendriks, Suili Bot
Children with selective mutism (SM) fail to speak in specific public situations (e.g., school), despite speaking normally in other situations (e.g., at home). The current study explored the phenomenon of SM in a sample of 57 non-clinical children aged 3-6 years. Children performed two speech tasks to assess their absolute amount of spoken words, while their parents completed questionnaires for measuring children's levels of SM, social anxiety and non-social anxiety symptoms as well as the temperament characteristic of behavioral inhibition...
February 2016: Child Psychiatry and Human Development
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