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Momchil Rizov, Petya Andreeva, Ivanka Dimova
Angiogenesis is an essential process for proper functioning of the female reproductive system and for successful pregnancy realization. The multitude of factors required for physiological angiogenesis and the complexity of regulation of their temporal-spatial activities contribute to aberrations in human fertilization and pregnancy outcomes. In this study, we reviewed the current knowledge of the temporal expression patterns, functions, and regulatory mechanisms of angiogenic factors during foliculogenesis, early implantation/placentation and embryo development, as well as recurrent spontaneous abortions...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
D M Magalhães, V R Araújo, I B Lima-Verde, M H T Matos, R C Silva, C M Lucci, S N Báo, C C Campello, J R Figueiredo
Porcine pituitary follicle stimulating hormone (pFSH) is known to regulate the production of growth factors that have an essential role in early foliculogenesis. However, the effects of different preparations of pFSH on the survival and development of caprine follicles are not yet known. The aim of this study was to evaluate the effects of different pFSH (Stimufol and Folltropin) on the in vitro survival and growth of caprine preantral follicles. Pieces of caprine ovarian tissues were cultured for either one or seven days in a supplemented Minimum Essential Medium, alone or containing either Stimufol (50 ng/mL) or Folltropin (10, 50, 100 and 1000 ng/mL)...
August 2009: Biocell: Official Journal of the Sociedades Latinoamericanas de Microscopía Electronica ... Et. Al
Siraam Cabrera-Vásquez
Neurotrophins (NTs) are important for the survival, differentiation and function of sympathetic and sensorial neurons of central and peripheral nervous system. However, similar functions have been described of NTs in non-neural organs. Nerve Growth factor (NGF) participates in the foliculogenesis and ovulation in the ovary, as well as in the islet morphogenesis and insulin secretion of the pancreatic beta cell. The NTs act by binding to two distinct classes of transmembranal receptors: p75 and Trks. Both receptor types lead to activation of intracellular signaling cascades that end with cell survival or apoptosis...
May 2007: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Błazej Meczekalski, Alina Warenik-Szymankiewicz
Oocyte specific genes play important role in the foliculogenesis, ovulation, fertilization and early embryogenesis. It is suggested that 17-20% of infertility in both sex has idiopathic aspect. This kind of infertility is mainly associated with genetic background. The study on the role of oocyte specific genes can help in our understanding of the causes of idiopathic infertility.
May 2005: Endokrynologia Polska
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