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Charlson Comorbidity Index

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https://www.readbyqxmd.com/read/28806373/patient-aligned-care-team-engagement-to-connect-veterans-experiencing-homelessness-with-appropriate-health-care
#1
Adi V Gundlapalli, Andrew Redd, Daniel Bolton, Megan E Vanneman, Marjorie E Carter, Erin Johnson, Matthew H Samore, Jamison D Fargo, Thomas P O'Toole
BACKGROUND: Veterans experiencing homelessness frequently use emergency and urgent care (ED). OBJECTIVE: To examine the effect of a Patient-aligned Care Team (PACT) model tailored to the unique needs of Veterans experiencing homelessness (H-PACT) on frequency and type of ED visits in Veterans Health Administration (VHA) medical facilities. RESEARCH DESIGN: During a 12-month period, ED visits for 3981 homeless Veterans enrolled in (1) H-PACT at 20 VHA medical centers (enrolled) were compared with those of (2) 24,363 homeless Veterans not enrolled in H-PACT at the same sites (nonenrolled), and (3) 23,542 homeless Veterans at 12 non-H-PACT sites (usual care) using a difference-in-differences approach...
September 2017: Medical Care
https://www.readbyqxmd.com/read/28806302/surgery-for-primary-hyperparathyroidism-adherence-to-consensus-guidelines-in-an-academic-health-system
#2
Eric J Kuo, Mostafa A Al-Alusi, Lin Du, Albert Shieh, Masha J Livhits, Angela M Leung, Michael W Yeh
OBJECTIVE: To determine the extent to which consensus guidelines for surgery in patients with primary hyperparathyroidism (PHPT) are followed within an academic health system. BACKGROUND: Previous studies have shown that adherence to consensus guidelines in community practice is low. METHODS: Adults with biochemically confirmed PHPT who received primary care within an academic health system were identified from 2005 to 2015. Multivariable logistic regression was used to analyze predictors of parathyroidectomy (PTx)...
August 11, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28805309/safety-of-herpes-zoster-vaccination-among-inflammatory-bowel-disease-patients-being-treated-with-anti-tnf-medications
#3
N Khan, Y Shah, C Trivedi, J D Lewis
BACKGROUND: The risk of herpes zoster (HZ) is elevated in inflammatory bowel disease (IBD) patients treated with anti-TNF medications. While it is optimal to give herpes zoster vaccine prior to initiation of therapy clinical circumstances may not always allow this. AIM: To determine the safety of giving herpes zoster vaccine while patients are on anti-TNF therapy. METHODS: We conducted a retrospective cohort study involving IBD patients who were followed in the Veterans Affairs (VA) healthcare system between 2001 and 2016...
August 14, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28804865/value-of-the-pitt-bacteraemia-score-to-predict-short-term-mortality-in-staphylococcus-aureus-bloodstream-infection-a-validation-study
#4
Jan A Roth, Sarah Tschudin-Sutter, Marc Dangel, Reno Frei, Manuel Battegay, Andreas F Widmer
BACKGROUND AND AIMS: The widely used Pitt Bacteraemia Score (PBS) has repeatedly been described as a risk factor for short-term mortality in Staphylococcus aureus bloodstream infection (BSI), but little is known about its overall predictive performance. We therefore aimed to externally validate the PBS in S. aureus BSIs. METHODS: We performed a retrospective validation study at the University Hospital Basel. Adult patients with a first episode of methicillin-susceptible S...
August 14, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28804571/impact-of-comorbidity-on-waiting-list-and-post-transplant-outcomes-in-patients-undergoing-liver-retransplantation
#5
Mohammad A B Al-Freah, Carl Moran, Matthew R Foxton, Kosh Agarwal, Julia A Wendon, Nigel D Heaton, Michael A Heneghan
AIM: To determine the impact of Charlson comorbidity index (CCI) on waiting list (WL) and post liver retransplantation (LRT) survival. METHODS: Comparative study of all adult patients assessed for primary liver transplant (PLT) (n = 1090) and patients assessed for LRT (n = 150), 2000-2007 at our centre. Demographic, clinical and laboratory variables were recorded. RESULTS: Median age for all patients was 53 years and 66% were men. Median model for end stage liver disease (MELD) score was 15...
July 18, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28803034/variations-in-the-costs-of-radical-cystectomy-for-bladder-cancer-in-the-usa
#6
Jeffrey J Leow, Alexander P Cole, Thomas Seisen, Joaquim Bellmunt, Matthew Mossanen, Mani Menon, Mark A Preston, Toni K Choueiri, Adam S Kibel, Benjamin I Chung, Maxine Sun, Steven L Chang, Quoc-Dien Trinh
BACKGROUND: Radical cystectomy (RC) for muscle-invasive bladder cancer (BCa) has potential for serious complications, prolonged length of stay and readmissions-all of which may increase costs. Although variations in outcomes are well described, less is known about determinants driving variation in costs. OBJECTIVE: To assess surgeon- and hospital-level variations in costs and predictors of high- and low-cost RC. DESIGN, SETTING, AND PARTICIPANTS: Cohort study of 23 173 patients who underwent RC for BCa in 208 hospitals in the USA from 2003 to 2015 in the Premier Healthcare Database...
August 9, 2017: European Urology
https://www.readbyqxmd.com/read/28800719/total-ankle-arthroplasty-comparing-perioperative-outcomes-when-performed-at-an-orthopaedic-specialty-hospital-versus-an-academic-teaching-hospital
#7
David M Beck, Eric M Padegimas, David I Pedowitz, Steven M Raikin
BACKGROUND: The number of total ankle arthroplasties (TAAs) performed in the United States has risen significantly in recent years, as has utilization of orthopaedic specialty hospital (OSH) to treat healthy patients undergoing elective surgery. The purpose of this study was to compare postoperative outcomes following TAA at an OSH when compared with a matching population of patients undergoing TAA at an academic teaching hospital (ATH). METHODS: We identified all TAA from January 2014 to December 2014 at the OSH and January 2010 to January 2016 at the ATH...
August 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28796021/psychotropics-environmental-temperature-and-hospital-outcomes-in-older-medical-patients
#8
Arduino A Mangoni, Feruza Kholmurodova, Lidia Mayner, Paul Hakendorf, Richard J Woodman
PURPOSE: The authors investigated whether the use of psychotropics and environmental temperature on admission influence hospital length of stay (LOS) and mortality in older medical patients. METHODS: Clinical and demographic characteristics, Charlson Comorbidity Index, use of psychotropic and nonpsychotropic drugs, hospital LOS, and mortality were retrospectively collected in medical patients 65 years and older (n = 382) admitted to a metropolitan teaching hospital during 5 consecutive heat waves (HWs) between 2007 and 2009...
August 8, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28782449/real-world-economic-burden-of-hematopoietic-cell-transplantation-among-a-large-us-commercially-insured-population-with-hematologic-malignancies
#9
Machaon Bonafede, Akshara Richhariya, Qian Cai, Neil C Josephson, Donna McMorrow, Phillip M Garfin, Miguel-Angel Perales
AIMS: Approximately 20,000 hematopoietic cell transplantation (HCT) procedures are performed in the US annually. This study aims to study the healthcare resource utilization and costs among commercially-insured patients with hematologic malignancies who received autologous HCT (auto-HCT) and allogeneic HCT (allo-HCT) in the US. MATERIALS AND METHODS: Adult patients with hematologic malignancies undergoing auto- or allo-HCT between January 1, 2011 and June 30, 2014 were identified in the Truven Health MarketScan Research Databases...
August 7, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28781973/comparison-of-30-day-morbidity-and-mortality-after-arthroscopic-bankart-open-bankart-and-latarjet-bristow-procedures-a-review-of-2864-cases
#10
Steven L Bokshan, Steven F DeFroda, Brett D Owens
BACKGROUND: Surgical intervention for anterior shoulder instability is commonly performed and is highly successful in reducing instances of recurrent instability. PURPOSE: To determine and compare the incidence of 30-day complications and patient and surgical risk factors for complications for arthroscopic Bankart, open Bankart, and Latarjet-Bristow procedures. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: All arthroscopic Bankart, open Bankart, and Latarjet-Bristow procedures from 2005 to 2014 from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) prospective database were analyzed...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28781008/-prognostic-value-of-assessment-tools-on-elderly-patients-with-chronic-advanced-disease-and-end-of-life-admitted-to-an-intermediate-care-centre
#11
Elizabeth da Costa, María José Robles, María Dolores Sánchez-Rodríguez, Olga Vázquez-Ibar, Ramón Miralles
OBJECTIVE: To apply 3advanced chronic disease evaluation tools in elderly patients admitted to an intermediate and long-term care centre, and evaluate its relationship with mortality. METHODS: The NECPAL tool, PROFUND prognostic index, and Charlson comorbidity index were applied to 87 patients. RESULTS: The NECPAL tool identified 31 patients (35.6%) in need of palliative care, and according to the PROFUND index, 45 (54.7%) had high/very high risk of mortality (≥7 points), and according to Charlson index, 31 (35...
August 3, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28780697/persistence-with-vka-treatment-in-newly-treated-atrial-fibrillation-patients-an-analysis-based-on-a-large-sample-of-38-076-german-patients
#12
Thomas Wilke, Antje Groth, Andreas Fuchs, Matthias Pfannkuche, Ulf Maywald
PURPOSE: The aim of this study was to describe persistence with vitamin K antagonist (VKA) treatment in German atrial fibrillation (AF) patients and to identify factors which may be associated with early discontinuation of VKA therapy. METHODS: We did a retrospective cohort study based on an anonymized German claims dataset with VKA treatment-naïve AF patients, who received at least one VKA prescription. VKA therapy discontinuation was defined as a gap >180 days...
August 5, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28777676/benefits-of-supplemental-jejunostomy-tube-feeding-during-neoadjuvant-therapy-in-patients-with-locally-advanced-potentially-resectable-esophageal-cancer
#13
Brian G A Dalton, Adam J Friedant, Stacey Su, Tiffany A P Schatz, Karen J Ruth, Walter J Scott
BACKGROUND: Standard treatment for locally advanced esophageal cancer includes neoadjuvant therapy followed by surgical resection. However, many patients experience a period of decreased oral intake during neoadjuvant treatment and are at risk for malnutrition. We hypothesize that use of jejunostomy tube (j-tube) feedings during neoadjuvant therapy in selected patients may be associated with better perioperative outcomes. METHODS: A prospectively collected database at a single institution was retrospectively analyzed...
August 4, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28777196/adaptation-of-the-acute-organ-failure-score-for-use-in-a-medicare-population
#14
Katherine R Courtright, Scott D Halpern, Brian Bayes, Michael O Harhay, Eli Raneses, Patricia Kipnis, Gabriel J Escobar, Meeta Prasad Kerlin
OBJECTIVES: Without widely available physiologic data, a need exists for ICU risk adjustment methods that can be applied to administrative data. We sought to expand the generalizability of the Acute Organ Failure Score by adapting it to a commonly used administrative database. DESIGN: Retrospective cohort study. SETTING: One hundred fifty-one hospitals in Pennsylvania. PATIENTS: A total of 90,733 ICU admissions among 77,040 unique patients between January 1, 2009, and December 1, 2009, in the Medicare Provider Analysis and Review database...
August 2, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28772007/the-impact-of-comorbidities-on-tumor-necrosis-factor-inhibitor-therapy-in-psoriatic-arthritis-a-population-based-cohort-study
#15
Christine Ballegaard, Pil Højgaard, Lene Dreyer, René Cordtz, Tanja Schjødt Jørgensen, Marie Skougaard, Simon Tarp, Lars Erik Kristensen
OBJECTIVE: The objective of this population-based cohort study was to investigate the impact of comorbidities on disease activity, treatment response and persistence with the first-tried tumor necrosis factor inhibitor (TNFi) in patients with psoriatic arthritis (PsA). METHODS: Data on patient characteristics, disease activity and treatment response and persistence was obtained from the DANBIO registry. Information on comorbidities according to the Charlson Comorbidity Index (CCI) was obtained through linkage with the Danish National Patient Register...
August 3, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28771654/predictors-of-30-day-mortality-in-hospitalized-patients-with-clostridium-difficile-infection
#16
Jayakrishna Chintanaboina, Seyedehsan Navabi, Kristen Suchniak-Mussari, Benjamin Stern, Simranjit Bedi, Erik B Lehman, Andrew Tinsley
OBJECTIVES: Clostridium difficile infection (CDI) is a significant cause of morbidity and mortality and is the most common nosocomial infection in the United States, with associated annual costs of approximately $3 billion. The epidemiology of CDI has changed with the identification of novel risk factors for incident and recurrent CDI. The aim of this study was to identify the predictors of 30-day mortality in hospitalized patients with CDI. METHODS: We identified all of the patients diagnosed as having CDI from January 2011 to December 2014 at our university-setting hospital...
August 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28768480/internet-and-social-network-users-profiles-in-renal-transplant-recipients-in-france
#17
Yosra Mouelhi, Marine Alessandrini, Vanessa Pauly, Bertrand Dussol, Stéphanie Gentile
BACKGROUND: The use of the Internet for searching and sharing health information and for health care interactions may have a great potential for Renal Transplant Recipients (RTR). This study aims to determine the characteristics associated with Internet and social network use in a representative sample of RTR at the time of their inclusion in the study. METHODS: Data of this cross-sectional design is retrieved from a longitudinal study conducted in five French kidney transplant centers in 2011, and included Renal Transplant Recipients aged 18 years with a functioning graft for at least 1 year...
August 3, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28767571/candida-vertebral-osteomyelitis-cvo-28-cases-from-a-10-year-retrospective-study-in-france
#18
Clémence Richaud, Victoire De Lastours, Xavière Panhard, David Petrover, Fantin Bruno, Agnès Lefort
Although increasingly frequent, little is known about the clinical presentation, radiological signs, and outcome of Candida vertebral osteomyelitis (CVO).We performed a nationwide retrospective study of laboratory-confirmed cases of CVO over a 10 year-period in France with a prolonged follow-up. We describe demographic, clinical, biological, and radiological characteristics of patients with CVO, patients' management, and long-term outcome and determine factors associated with a poor outcome.In total, 28 patients with laboratory-confirmed CVO were included...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28767515/35-year-trends-in-first-time-hospitalization-for-hip-fracture-one-year-mortality-and-the-prognostic-impact-of-comorbidity-a-danish-nationwide-cohort-study-1980-2014
#19
Alma B Pedersen, Vera Ehrenstein, Szimonetta Szépligeti, Astrid Lunde, Ylva Trolle Lagerros, Anna Westerlund, Grethe S Tell, Henrik T Sørensen
BACKGROUND: We examined trends in hip fracture incidence in Denmark from 1980 to 2014, trends in subsequent one-year mortality, and the prognostic impact of sex, age, and comorbidity. METHODS: This nationwide cohort study prospectively collected data from population-based Danish registries. We included 262,437 patients with incident hip fracture and assessed comorbidity using the Charlson Comorbidity Index (CCI). RESULTS: Despite slight increases in incidence rates (IRs) of hip fracture up to the mid-1990s, the annual IR decreased by 29% from 1980 to 2014 in women, but remained stable in men...
July 31, 2017: Epidemiology
https://www.readbyqxmd.com/read/28767447/prevalence-and-survival-prognosis-of-prostate-cancer-in-patients-with-end-stage-renal-disease-a-retrospective-study-based-on-the-korea-national-database-2003-2010
#20
Sung Han Kim, Jae Young Joung, Yoon Seok Suh, Young Ae Kim, Jin Hyuk Hong, Tong Sun Kuark, Eun Sook Lee, Kang Hyun Lee
OBJECTIVE: The study was aimed to evaluate the prevalence and prognosis of prostate cancer (PC) and end-stage renal disease (ESRD), determine the risk factors for overall survival (OS) and PC-specific survival (CSS), and evaluate differences in PC-related clinical therapeutic patterns between patients with and without PC-ESRD. METHODS: This observational population study, performed at the National Cancer Center and Cancer Research Institute in Korea, included patients with PC and ESRD from the nationwide Korean Health Insurance System and Korean Central Cancer Registry data...
July 22, 2017: Oncotarget
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