keyword
https://read.qxmd.com/read/38628932/microvascular-changes-are-associated-with-proteinuria-and-emg-changes-in-patients-with-type-2-diabetes-using-video-capillaroscopy
#1
JOURNAL ARTICLE
Alireza Rajaei, Pooneh Dehghan, Nikoo Emtiazi, Azadeh Afzalnia, Faraneh Farsad, Seyed Mohamad Hosseinian
Objectives: Video capillaroscopy is a diagnostic method for evaluating microvascular changes in type 2 diabetes mellitus (T2DM). This study evaluated microvascular changes, including microvascular architecture, capillary distribution (morphology and density), and angiogenesis conditions in T2DM patients via video capillaroscopy. Methods: A total of 256 patients with T2DM enrolled in this study. Based on electromyography (EMG)-nerve conduction velocity results, patients were divided into patients with normal and abnormal EMG...
March 25, 2024: Annals of Vascular Diseases
https://read.qxmd.com/read/38527621/electrodiagnostic-severity-does-not-predict-short-to-mid-term-outcomes-of-cubital-tunnel-release-surgery
#2
JOURNAL ARTICLE
Nicholas Pohl, Parker Brush, Meghan Foos, Samuel Alfonsi, Pedro Beredjiklian, Daniel Fletcher
HYPOTHESIS: This study aimed to explore the prognostic value of electrodiagnostic studies (EDS) to clarify their utility in clinical practice prior to cubital tunnel release surgery as well as identify patient factors associated with patient-reported functional improvement after surgery. Our hypothesis is that patients with severe preoperative findings on EDS will tend to experience less functional improvement after surgery given the extent of ulnar nerve compressive injury. METHODS: Patients with cubital tunnel syndrome and preoperative electrodiagnostic data treated from 2012-2022 with cubital tunnel release were assessed regarding demographic information, preoperative physical exam findings, EDS findings, postoperative complications, and patient-reported outcomes...
March 23, 2024: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38439568/pathologic-classification-of-a-late-onset-peripheral-neuropathy-in-a-spontaneous-labrador-retriever-dog-model
#3
JOURNAL ARTICLE
Ryan S Anderson, Alexander K Chu, Helena Rylander, Emily E Binversie, Ian D Duncan, Lauren Baker, Shahriar Salamat, Margaret M Patterson, Jordan Gruel, Nyah L Kohler, Hannah K Kearney, Shelby M Ale, Mehdi M Momen, Peter Muir, John P Svaren, Rebecca Johnson, Susannah J Sample
Late-onset peripheral neuropathy (LPN) is a heritable canine neuropathy commonly found in Labrador retrievers and is characterized by laryngeal paralysis and pelvic limb paresis. Our objective was to establish canine LPN as a model for human hereditary peripheral neuropathy by classifying it as either an axonopathy or myelinopathy and evaluating length-dependent degeneration. We conducted a motor nerve conduction study of the sciatic and ulnar nerves, electromyography (EMG) of appendicular and epaxial musculature, and histologic analysis of sciatic and recurrent laryngeal nerves in LPN-affected and control dogs...
March 2024: Journal of Comparative Neurology
https://read.qxmd.com/read/38333661/a-couple-of-the-first-cousins-born-with-hypotonia-and-maternal-polyhydramnios
#4
Mousa Ahmadpour-Kacho, Yadollah Zahed Pasha, Samira Pournajaf
UNLABELLED: Congenital myotonic dystrophy should be considered in hypotonic infants with polyhydramniotic mothers with a positive history of myotonia. ABSTRACT: Congenital myotonic dystrophy (CDM) is a predominantly maternally inherited disease and results from increased numbers of cytosine, thymine, and guanine (CTG) repeats in the unstable DNA regions and presents as hypotonia in the neonatal period and myotonia in adulthood. This report aims to present two cases of CDM...
February 2024: Clinical Case Reports
https://read.qxmd.com/read/38325357/combined-central-and-peripheral-demyelination-ccpd-two-case-reports
#5
Buse Gül Belen, Nazlı Gamze Bülbül, Sibel Karsidag, Ercan Köse, Atay Vural, Fatih Özdağ
Combined central and peripheral demyelination (CCPD) is is a rare disease characterized by demyelinating lesions in both the central nervous system (CNS) and peripheral nervous system (PNS). CCPD can present with acute, subacute or chronic onset. The initial symptom may be of CNS origin, PNS origin or both. The clinical manifestations of CCPD are quite heterogeneous, and there are no well-defined diagnostic criteria. In MRI imaging of CCPD cases, demyelinating lesions can be seen in areas such as the brain, cerebellum, brainstem, optic nerve, and spinal cord...
February 7, 2024: European Neurology
https://read.qxmd.com/read/38313916/a-study-of-sensory-nerve-conduction-in-pre-and-post-immunoglobulin-treatment-of-guillain-barr%C3%A3-syndrome
#6
JOURNAL ARTICLE
Prashanth A, Vinod Shende, Sachin Pawar
BACKGROUND: Guillain-Barré syndrome (GBS) is a condition characterized by acute and progressive weakness that impacts the limbs, facial muscles, and bulbar muscles due to acute polyneuro-radiculopathy. Typically, an infection that results in immune-mediated nerve dysfunction is what starts the disease. Patients often encounter paresthesia or discomfort before progressing to muscle weakness, initially in the lower extremities (which may include some proximal components) and subsequently in the upper extremities...
January 2024: Curēus
https://read.qxmd.com/read/38259866/new-onset-anca-associated-vasculitis-presenting-with-neuropathy-after-covid-19-infection-a-case-report-and-literature-review
#7
Aida Mohamadi, Somayeh Soroureddin, Sepehr Nayebirad, Zahra Tamartash, Maryam Mohebbi, Hoda Kavosi
Coronavirus Disease 2019 (COVID-19) is a viral infection caused by SARS-CoV-2, which can trigger autoimmune diseases such as antineutrophilic cytoplasmic antibody (ANCA) associated vasculitis (AAV) that affect small and medium-sized blood vessels in multiple organs. This study discusses a case with neuropathy and positive ANCA after COVID-19 infection and reviews the literature on AAV following COVID-19 infection. A 59-year-old man is presented that was referred to Shariati Hospital for evaluation of neurologic problems after a COVID-19 infection...
January 2024: Clinical Case Reports
https://read.qxmd.com/read/38151742/temporary-and-highly-variable-recovery-of-neuromuscular-dysfunction-by-electrical-stimulation-in-the-follow-up-of-acute-critical-illness-neuromyopathy-a-pilot-study
#8
JOURNAL ARTICLE
Madona Sekhniashvili, Petra Baum, Klaus V Toyka
BACKGROUND: In sepsis-associated critical illness neuromyopathy (CIPNM) serial electrical stimulation of motor nerves induces a short-lived temporary recovery of compound muscle action potentials (CMAPs) termed facilitation phenomenon (FP). This technique is different from other stimulation techniques published. The identification of FP suggests a major functional component in acute CIPNM. METHODS: From our previous study cohort of 18 intensive care unit patients with sepsis associated CIPNM showing profound muscle weakness and low or missing CMAPs on nerve conduction studies, six patients with different severity could be followed...
December 28, 2023: Neurological research and practice
https://read.qxmd.com/read/38143455/the-characteristics-of-guillain-barre-syndrome-in-children-in-pre-covid-19-and-during-the-covid-19-pandemic-a-cross-sectional-study
#9
JOURNAL ARTICLE
Sepide Javankiani, Amir Nasrollahizadeh, Behdad Gharib, Morteza Heidari, Sara Memarian
BACKGROUND AND AIMS: In the pathophysiology of Guillain-Barre syndrome (GBS), inflammation and immunity are believed to play a key role. The neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), and platelet-lymphocyte ratio (PLR) have been recently identified as potential markers of inflammation or immunity. This study aimed to investigate whether NLR, MLR, and PLR are associated with GBS characteristics in children. We also assessed the impact of the COVID-19 pandemic on the characteristics of GBS in Iran...
December 2023: Health Science Reports
https://read.qxmd.com/read/38046582/case-report-ultrasound-guided-median-nerve-electrical-stimulation-on-functional-recovery-of-hemiplegic-upper-limb-after-stroke
#10
Rui Li, Ping Zhang, Jingyi Lu, Jianlin Zhuang, Meiqi Wang, Hongmei Fang, Xiaowei Zhang, Ying Gao, Zhufen Yang, Kai Ling Chin
BACKGROUND: Functional restoration of hemiplegic upper limbs is a difficult area in the field of neurological rehabilitation. Electrical stimulation is one of the treatments that has shown promising advancements and functional improvements. Most of the electrical stimulations used in clinical practice are surface stimulations. In this case, we aimed to investigate the feasibility of a minimally invasive, ultrasound-guided median nerve electrical stimulation (UG-MNES) in improving the upper limb motor function and activity of a patient with right-sided hemiparesis...
2023: Frontiers in Neurology
https://read.qxmd.com/read/38046482/management-of-brachioradial-pruritus-with-cervical-epidural-steroid-injection-a-case-report
#11
Haroutiun Hamzoian, Maha Alkhayat, Michel Abdelmasih, Shehzad Choudry
Brachioradial pruritus (BRP) is a neuropathic dysesthesia described as itching over the dorsolateral forearm. The etiology of BRP has not been fully identified but is hypothesized to be multifactorial, including sun exposure and cervical spine disease. Management of BRP is challenging, and conservative measures often fail to provide notable improvement. We present a case of a 71-year-old woman with BRP refractory to topical and oral treatment, with radiographic evidence of cervical spinal canal and neuroforaminal stenosis...
October 2023: Curēus
https://read.qxmd.com/read/38028101/guillain-barre-syndrome-after-antithymocyte-globulin-administration-in-a-kidney-transplant-recipient-a-case-report-and-literature-review
#12
Farnaz Tavakoli, Davood Dalil, Fatemeh Yaghoubi, Seyyed Mohammad Hosseini
This report describes a rare case of developing Guillain-Barre syndrome (GBS) following receiving rabbit antithymocyte globulin (ATG) after kidney transplantation to prevent acute allograft rejection in a 34-year-old man. The patient presented severe pain in the right temporomandibular joint, fever, chills, myalgia, polyarthralgia, and bone pain. Twelve hours later, he developed quadriplegia, paresthesia, and a limited range of active motions in all extremities. No antecedent viral or bacterial infection was identified...
November 2023: Clinical Case Reports
https://read.qxmd.com/read/37980590/effects-of-an-exoskeleton-on-muscle-activity-in-tasks-requiring-arm-elevation-part-i-experiments-in-a-controlled-laboratory-setting
#13
JOURNAL ARTICLE
Satu Mänttäri, Ari-Pekka Rauttola, Janne Halonen, Jutta Karkulehto, Pihla Säynäjäkangas, Juha Oksa
BACKGROUND: Long-term work with elevated arms, or overhead work, is a risk factor for musculoskeletal complaints and disorders. Upper-limb exoskeletons are a promising tool for reducing occupational workload when working with hands above shoulder level. OBJECTIVE: The purpose of this study was to assess the effects of upper-limb exoskeleton on muscular and physical strain and perceived exertion during dynamic work at four different shoulder joint angles. Further, we evaluated if there are any negative effects associated with the use of exoskeleton...
November 17, 2023: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/37822484/axonal-sensory-motor-polyneuropathy-in-ankylosing-spondylitis-a-case-report
#14
Amirreza Khalaji, Susan Kolahi, Leyla Ghadakchi, Mehdi Jafarpour
KEY CLINICAL MESSAGE: In ankylosing spondylitis cases, axonal-type sensory-motor polyneuropathy is a rare manifestation and should be considered an underlying etiology in patients with unexplained neuropathy. ABSTRACT: This case report discusses a 45-year-old male diagnosed with ankylosing spondylitis (AS), a chronic inflammatory disorder affecting the axial skeleton and peripheral joints. The patient presented with polyneuropathy, characterized by tingling and numbness in the upper and lower limbs, which is an uncommon manifestation of AS...
October 2023: Clinical Case Reports
https://read.qxmd.com/read/37797217/homozygous-mutations-in-gdap1-and-mfn2-genes-resulted-in-autosomal-recessive-forms-of-charcot-marie-tooth-disease-in-consanguineous-pakistani-families
#15
JOURNAL ARTICLE
Muhammad Asif, Chien-Chun Chiou, Malik Fiaz Hussain, Manzoor Hussain, Zureesha Sajid, Muhammad Gulsher, Afifa Raheem, Adil Khan, Nasreen Nasreen, Andrzej Kloczkowski, Mubashir Hassan, Furhan Iqbal, Chien-Chin Chen
Charcot-Marie-Tooth disease (CMT) is a heritable neurodegenerative disease of peripheral nervous system diseases in which more than 100 genes and their mutations are associated. Two consanguineous families Dera Ghazi Khan (PAK-CMT1-DG KHAN) and Layyah (PAK-CMT2-LAYYAH) with multiple CMT-affected subjects were enrolled from Punjab province in Pakistan. Basic epidemiological data were collected for the subjects. Nerve conduction study (NCS) and electromyography (EMG) were performed for the patients. Whole-exome sequencing (WES) followed by Sanger sequencing was applied to report the genetic basic of CMT...
October 5, 2023: DNA and Cell Biology
https://read.qxmd.com/read/37752633/long-term-evaluation-of-ulnar-nerve-function-in-patients-with-distal-humerus-fractures-treated-with-open-reduction-and-internal-fixation-a-nerve-conduction-study
#16
JOURNAL ARTICLE
Serkan Bayram, Yaşar Samet Gökçeoğlu, Alper Şükrü Kendirci, Koray Şahin, Fatih Şentürk, Mehmet Barış Baslo, Ali Erşen
OBJECTIVES: To investigate the long-term evaluation with electromyography of ulnar nerve function in patients with distal humerus fractures (DHFs) treated with open reduction and internal fixation. DESIGN: Retrospective cohort study. SETTING: Level 1 trauma center. PATIENTS: Fifty-two patients (20 men and 32 women) with DHFs. INTERVENTIONS: All patients underwent open reduction and internal fixation between 2002 and 2017 with a minimum five years' follow-up...
September 25, 2023: Journal of Orthopaedic Trauma
https://read.qxmd.com/read/37701248/postpartum-sciatic-neuropathy-after-uncomplicated-vaginal-delivery
#17
Nader Boutros, Dina Saba, Bhavesh Trikamji
Postpartum neuropathies are common, including femoral neuropathy, peroneal neuropathy, lumbosacral trunk plexopathy, and lateral femoral cutaneous neuropathy. Sciatic mononeuropathy in the peripartum period is rare. Postpartum sciatic neuropathy (PSN) in the setting of cesarean section has been reported before. We present a case series of 2 sciatic mononeuropathies after vaginal delivery. Case 1 is a 25-year-old woman who presented with a left foot drop after normal vaginal delivery after being in labor for 3 hours...
October 2023: Neurohospitalist
https://read.qxmd.com/read/37654763/delayed-recovery-of-idiopathic-common-peroneal-nerve-palsy-after-total-knee-arthroplasty-a-rare-case-report
#18
Amyn M Rajani, Anmol R S Mittal, Vishal U Kulkarni, Khushi A Rajani, Kashish A Rajani
INTRODUCTION: Common peroneal nerve palsy (CPNP) is a rare complication post total knee arthroplasty (TKA). Even though it is diagnosed acutely, the recovery potential is just over 50%. The average period for complete recovery in such cases is 5 months; however, the management remains controversial. Through this report, we present one such case of left sided complete CPNP after bilateral TKA who was conserved with various modalities. Even though the recovery was delayed, the patient made full recovery...
August 2023: Journal of Orthopaedic Case Reports
https://read.qxmd.com/read/37529812/action-myoclonus-renal-failure-syndrome-a-case-report-with-bioinformatic-annotations
#19
Hakan Ekmekci, Omar Qutob, Huseyn Babayev, Ali Şahin
Action myoclonus-renal failure (AMRF) syndrome is a rare autosomal recessive disorder characterized by myoclonic epilepsy with occasional renal failure comorbidity. This study examines a consanguineous family with multiple members presenting myoclonic epilepsy. The disease's continued transmission within the family is attributable to a lack of genetic testing and the inability to establish a definitive diagnosis. Our objective is to guide physicians toward accurate diagnoses and reduce the disease's recurrence through appropriate genetic counseling...
July 2023: Curēus
https://read.qxmd.com/read/37529140/fast-acting-sub-perception-spinal-cord-stimulation-for-a-case-of-painful-diabetic-polyneuropathy-just-an-antalgic-treatment-or-even-a-therapy
#20
Ezio Amorizzo, Francesca De Sanctis, Gianni Colini Baldeschi
INTRODUCTION: Painful diabetic polyneuropathy (P-DPN) occurs in 20% - 30% of diabetic patients. Currently, therapeutic strategies include lifestyle modifications, good glycemic control, and neuropathic pain drugs. Spinal cord stimulation (SCS) has been shown to be successful in patients who have not responded to other treatments. The American Diabetes Association strongly recommends early screening and diagnosis for this condition through clinical tests and nerve conduction study (NCS)...
April 2023: Anesthesiology and Pain Medicine
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