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https://www.readbyqxmd.com/read/29081097/-effect-of-nerve-growth-factor-on-chronic-peripheral-neuropathy-in-rats-induced-by-1-bromopropane
#1
J Y Wu, J B Zhang, W J Chen, D Y Sun
Objective: To observe the effect of nerve growth factor (NGF) and Mecobalamin on chronic peripheral neuropathy in rats induced by 1-bromopropane. Methods: 36 male SD rats were exposed to 1-bromopropane vapor at concentrations of 4 000 mg/m(3), 6 hours per day, 5 days per week for 12 weeks. The rats were randomed divided into 4 groups, and treated by Mecobalamin for 300 μg/kg qd, NGF for 40 μg/kg qd, Mecobalamin+NGF with the dose as mentioned above, respecively. The control group were fed in normal condition...
July 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28946515/effects-of-biofeedback-versus-switch-triggered-functional-electrical-stimulation-on-sciatica-related-foot-drop
#2
Dragos Petrica Sardaru, Daniela Matei, Dan Zaharia-Kezdi, Liviu Pendefunda
BACKGROUND: Sciatica-related Foot Drop is a peripheral nervous condition that produces a loss of power in the ankle dorsiflexion muscles. Functional electrical stimulation is a modality of electrical stimulation that produces muscle contraction in a functional movement of the limb. This technique was utilized with positive effects in central nervous afflictions but it is not known whether or not it has any influence in motor recovery following peripheral nervous system problems. This study aims to clarify the effects of functional electrical stimulation on foot drop caused by peripheral nerve compression resulting from lumbar disc herniation...
September 8, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28832192/trends-in-the-surgical-treatment-for-cubital-tunnel-syndrome-a-survey-of-members-of-the-american-society-for-surgery-of-the-hand
#3
Ayesha Yahya, Andrew R Malarkey, Ryan L Eschbaugh, H Brent Bamberger
BACKGROUND: Cubital tunnel syndrome is the second most common compression neuropathy affecting the upper extremity. The aim of this study was to determine the preferred surgical treatment for cubital tunnel syndrome by members of the American Society for Surgery of the Hand (ASSH). METHODS: We invited members of the ASSH research mailing list to complete our online survey. They were presented with 6 hypothetical cases and asked to choose their preferred treatment from the following options: open in situ decompression, endoscopic decompression, submuscular transposition, subcutaneous transposition, medial epicondylectomy, and conservative management...
August 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28606158/open-surgical-implantation-of-a-viable-cryopreserved-placental-membrane-after-decompression-and-neurolysis-of-common-peroneal-nerve-a-case-series
#4
E Rodriguez-Collazo, Y Tamire
BACKGROUND: The purpose of this study is to report on the rehabilitative outcomes associated with common peroneal nerve (CPN) decompression and neurolysis revision when performed with open surgical implantation of a viable cryopreserved placental membrane (vCPM). METHODS: Seven patients who underwent secondary CPN decompression and neurolysis with open surgical implantation of a viable cryopreserved placental membrane (vCPM) after previously failed surgery without vCPM utilization were identified through a retrospective medical record review and outcomes were analyzed...
June 12, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28593000/ultrasound-and-emg-ncv-study-electromyography-and-nerve-conduction-velocity-correlation-in-diagnosis-of-nerve-pathologies
#5
REVIEW
Shilpa Domkundwar, Gayatri Autkar, S V Khadilkar, Mayur Virarkar
PURPOSE: Nerve disorders are commonly encountered in clinical practice. Ultrasonography (USG) is a useful modality in the evaluation of most of the peripheral and superficial pathologies amenable to penetration by ultrasound. The primary objective is to study the USG findings of various peripheral nerve pathologies and to correlate them with electrophysiological (EMG-NCV) findings. METHOD: 42 patients referred with suspicion of peripheral nervous system affection were evaluated with USG along with EMG-NCV...
June 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28318780/surface-electromyogram-and-muscle-ultrasonography-for-detection-of-muscle-fasciculations-in-pediatric-peripheral-neuropathy
#6
Masayoshi Oguri, Yoshiaki Saito, Tetsuya Okazaki, Wataru Matsumura, Koyo Ohno, Masami Togawa, Chisako Fukuda, Yuko Saito, Ichizo Nishino, Yoshihiro Maegaki
A 12-year-old girl presented with talipes equinus of both legs, attenuation of upper and lower limb tendon reflexes, thermal hyperalgesia, and reduction of vibratory sensation. On clinical examination, muscle twitches of fingers of both hands, as well as the abductor halluces and the dorsal interossei muscles of the right foot were observed. Nerve conduction velocity was significantly declined in the upper and lower extremities. Needle electromyography (EMG) was not performed; however, ultrasonography revealed repetitive, semi-regular muscle twitches lasting 0...
August 2017: Brain & Development
https://www.readbyqxmd.com/read/28102815/assessment-of-the-characteristics-and-quality-of-life-of-patients-with-uremic-peripheral-neuropathy%C3%A2
#7
Xiu-Zhi Yu, Shi Lu, Wei Gou, Wei Wang, Shui-Hong Zou, Yin-Xia Han, Wei-Wei Wang, Jin-Yuan Zhang
OBJECTIVES: This study seeks to examine the characteristics and health-related quality of life (HRQL) of patients with uremic peripheral neuropathy. METHODS: Uremic patients undergoing maintenance hemodialysis (MHD) at our hospital were enrolled in this study. Data collection began in January 2011 and ended in June 2011. The patients were divided into two groups, the lesion group (110 cases) and the non-lesion group (168 cases), based on the presence or absence of peripheral neuropathy...
March 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28068938/acupuncture-combined-with-methylcobalamin-for-the-treatment-of-chemotherapy-induced-peripheral-neuropathy-in-patients-with-multiple-myeloma
#8
RANDOMIZED CONTROLLED TRIAL
Xiaoyan Han, Lijuan Wang, Hongfei Shi, Gaofeng Zheng, Jingsong He, Wenjun Wu, Jimin Shi, Guoqing Wei, Weiyan Zheng, Jie Sun, He Huang, Zhen Cai
BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) seriously affects the quality of life of patients with multiple myeloma (MM) as well as the response rate to chemotherapy. Acupuncture has a potential role in the treatment of CIPN, but at present there have been no randomized clinical research studies to analyze the effectiveness of acupuncture for the treatment of CIPN, particularly in MM patients. METHODS: The MM patients (104 individuals) who met the inclusion criteria were randomly assigned into a solely methylcobalamin therapy group (500 μg intramuscular methylcobalamin injections every other day for 20 days; ten injections) followed by 2 months of 500 μg oral methylcobalamin administration, three times per day) and an acupuncture combined with methylcobalamin (Met + Acu) group (methylcobalamin used the same way as above accompanied by three cycles of acupuncture)...
January 9, 2017: BMC Cancer
https://www.readbyqxmd.com/read/27790497/an-unusual-presentation-of-scrub-typhus
#9
Giridhar Reddy Banda, Srikrishna Raghavendra Boddu, Priyanka Ballal, Jayaprakash Belle
Presentation of scrub typhus associated with brachial neuritis is extremely rare with only a few cases reported so far. Here, we report a case of a 45-year-old female who presented with fever and right shoulder pain. Laboratory parameters showed leucocytosis with ELISA and PCR for scrub typhus positive. Electromyography (EMG) and Nerve Conduction Velocity (NCV) study was suggestive of brachial neuritis. She was given doxycycline therapy for 10 days following which her shoulder pain resolved.
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27693929/diagnostic-values-of-proset-magnetic-resonance-coronal-source-imaging-for-detecting-symptomatic-lesion-in-multiple-lumbar-foraminal-stenosis
#10
So Hee Park, Ikchan Jeon, Sang Woo Kim
OBJECTIVE: The aim of this study is to evaluate the values of ProSet magnetic resonance coronal source imaging (ProSet MR imaging) as a diagnostic tool for detecting symptomatic lesion in patients with multiple lumbar foraminal stenosis. PATIENTS AND METHODS: From January 2011 to June 2015, 46 patients with unilateral and single-level radiculopathy developed from foraminal stenosis were enrolled in the study. These diagnoses were confirmed with transforaminal selective nerve root block (SNRB) and electrophysiological testing, including electromyography and nerve conduction velocity (EMG/NCV) tests...
November 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27386647/-effect-of-tanshinone-iia-in-preventing-and-treating-oxaliplatin-induced-peripheral-neuropathy
#11
RANDOMIZED CONTROLLED TRIAL
Kai Xu, Wei-ting Cheng, Zuo-wei Hu, Wang Shan
OBJECTIVE: To observe preventive and therapeutic effects of Tanshinone IIA (T II A) on oxaliplatin induced peripheral neuropathy (OlPN) and to explore its effects on the expression of calcitonin gene related peptide (CGRP) and never growth factor (NGF). METHODS: Totally 36 phase II - III patients with malignant tumor of digestive tract undergoing chemotherapy program with oxaliplatin, were equally assigned to the T II A group (using THA at 80 mg/day 1 day before oxaliplatin chemotherapy for 3 successive days) and the control group (using chemotherapy program with oxaliplatin alone) by segmented randomization...
May 2016: Chinese Journal of Integrated Traditional and Western Medicine
https://www.readbyqxmd.com/read/27316242/motor-neuropathy-contributes-to-crouching-in-patients-with-dravet-syndrome
#12
Cyril Gitiaux, Nicole Chemaly, Susana Quijano-Roy, Christine Barnerias, Isabelle Desguerre, Marie Hully, Catherine Chiron, Olivier Dulac, Rima Nabbout
OBJECTIVE: Since SCN1A is expressed in the motor neuron initial segment, we explored whether motor neuron dysfunction could contribute to gait disturbance and orthopedic misalignment in patients with Dravet syndrome due to SCN1A mutations. METHODS: We assessed 12 consecutive patients who presented to our institution between January and March 2013. All of them were older than 2 years and were positive for the SCN1A mutation. We performed nerve conduction velocity studies and needle EMG recordings...
July 19, 2016: Neurology
https://www.readbyqxmd.com/read/27209097/electrodiagnostic-studies-in-presumptive-primary-hypothyroidism-and-polyneuropathy-in-dogs-with-reevaluation-during-hormone-replacement-therapy
#13
Elżbieta Gabriela Giza, Marta Płonek, Józef Marian Nicpoń, Marcin Adam Wrzosek
BACKGROUND: Peripheral neuropathy is the most common neurological manifestation of canine hypothyroidism. Data concerning electrodiagnostic studies in hypothyroid associated polyneuropathy in dogs are very limited and usually lack a reevaluation after hormone replacement therapy. The objective of this study was to perform a detailed, retrospective analysis of electromyographic (EMG), motor nerve conduction velocity (MNCV), F-wave and brainstem auditory evoked response (BAER) findings in 24 dogs with presumptive primary hypothyroidism and polyneuropathy with a comparison of the results before and after initiation of levothyroxine treatment with the assessment of the clinical outcome...
May 21, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/26934119/radiation-induced-brachial-plexopathy-in-patients-with-nasopharyngeal-carcinoma-a-retrospective-study
#14
Zhaoxi Cai, Yi Li, Zhen Hu, Ruying Fu, Xiaoming Rong, Rong Wu, Jinping Cheng, Xiaolong Huang, Jinjun Luo, Yamei Tang
Radiation-induced brachial plexopathy (RIBP) is one of the late complications in nasopharyngeal carcinoma (NPC) patients who received radiotherapy. We conducted a retrospective study to investigate its clinical characteristics and risk factors.Thirty-onepatients with RIBP after radiotherapy for NPC were enrolled. Clinical manifestations of RIBP, electrophysiologic data, magnetic resonance imaging (MRI), and the correlation between irradiation strategy and incidence of RIBP were evaluated. The mean latency at the onset of RIBP was 4...
April 5, 2016: Oncotarget
https://www.readbyqxmd.com/read/26684759/the-diagnostic-value-of-neuropathy-symptom-and-change-score-neuropathy-impairment-score-and-michigan-neuropathy-screening-instrument-for-diabetic-peripheral-neuropathy
#15
Qian Xiong, Bing Lu, Hongying Ye, Xia Wu, Tiansong Zhang, Yiming Li
AIMS: This study aims to evaluate the diagnostic capabilities of neuropathy symptom and change (NSC) score, neuropathy impairment score (NIS) and Michigan neuropathy screening instrument (MNSI) in diagnosing diabetic peripheral neuropathy (DPN). METHODS: A total of 131 patients with type II diabetes received NSC, NIS and MNSI scoring systems. Electromyography/nerve conduction velocity (EMG/NCV) test was taken as gold standard. Correlations between EMG/NCV test and the 3 scorings, and their sensitivity, specificity, positive and negative predictive values, accuracy and kappa (x03BA;) value were analyzed...
2015: European Neurology
https://www.readbyqxmd.com/read/26545312/a-rare-cause-of-ulnar-nerve-entrapment-at-the-elbow-area-illustrated-by-six-cases-the-anconeus-epitrochlearis-muscle
#16
J Fernandez, O Camuzard, M-O Gauci, M Winter
Ulnar nerve entrapment is the second most common compressive neuropathy after carpal tunnel syndrome. The accessory anconeus epitrochlearis muscle - present in 4% to 34% of the general population - is a known, but rare cause of ulnar nerve entrapment at the elbow. The aim of this article was to expand our knowledge about this condition based on six cases that we encountered at our hospital between 2011 and 2015. Every patient had a typical clinical presentation: hypoesthesia or sensory deficit in the fourth and fifth fingers; potential intrinsics atrophy of the fourth intermetacarpal space; loss of strength and difficulty with fifth finger abduction...
December 2015: Chirurgie de la Main
https://www.readbyqxmd.com/read/26509938/evaluation-of-pharyngeal-function-in-dogs-with-laryngeal-paralysis-before-and-after-unilateral-arytenoid-lateralization
#17
Natalia Andrade, Marc Kent, Elizabeth W Howerth, MaryAnn G Radlinsky
OBJECTIVE: To evaluate pharyngeal and laryngeal function using esophagography, topical pharyngeal/laryngeal sensitivity testing, and electromyography (EMG) in normal and dogs with idiopathic laryngeal paralysis (ILP) before and after unilateral arytenoid lateralization. STUDY: Prospective controlled cohort study. ANIMALS: Dogs with laryngeal paralysis (ILP; n = 8) and age/breed-matched (AB, n = 8) and young breed-matched dogs (B, n = 8) were recruited...
November 2015: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/26309529/electrophysiological-and-histopathological-effects-of-mesenchymal-stem-cells-in-treatment-of-experimental-rat-model-of-sciatic-nerve-injury
#18
Ercan Yarar, Enis Kuruoglu, Ersoy Kocabıcak, Adnan Altun, Eyup Genc, Hamit Ozyurek, Mehmet Kefeli, Abdullah Hilmi Marangoz, Keramettin Aydın, Cengiz Cokluk
AIM: The aim of this study was to evaluate electrophysiological and histopathological effects of mesenchymal stem cells in treatment of sciatic nerve injury. MATERIAL AND METHODS: Thirty-two female Spraque-Dawley rat were used in this study. Eight rats were used as a reference group in electrophysiological analysis for evaluation of non-injured nerve recordings (Control Group). Twenty-four rats were used for experimental evaluation. Twelve rats were anastomosed without treatment with mesenchymal stem cells (Sham Group) and twelve other rats were anastomosed and treated with mesenchymal stem cells (Stem Cell Group)...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26290858/laser-therapy-after-repair-of-the-distal-half-of-the-median-nerve-a-comparative-study
#19
Kamal Seyed Forootan, Siamak Farokh Forghani, Seyed Pezhman Madani, Hamid Karimi Estahbanati, Nazilla Sadat Seyed Forootan
BACKGROUND: Nerve injuries resulting from major or minor trauma often cause some disabilities for patients. Neurotmesis, characterized by complete anatomical rupture of the nerve, is the most severe form of the injury which will not recover without reconstructive surgery and nowadays such neural damages are improved by microsurgical procedures. Some studies have used low power laser for nerve cell growth in order to improve the rehabilitation results of peripheral nerves. Low power laser can complement the reformation of postsurgical nerve injuries...
May 2015: Trauma Monthly
https://www.readbyqxmd.com/read/26231964/diagnosis-and-treatment-of-work-related-proximal-median-and-radial-nerve-entrapment
#20
REVIEW
Gregory T Carter, Michael D Weiss
Proximal median (PMNE) and radial (RNE) nerve entrapment syndromes are uncommon. This article provides an evidenced-based treatment guideline for PMNE and RNE based on the available literature. Arriving at an accurate diagnosis must involve an electrodiagnostic (EDx) workup. EDx, including nerve conduction velocity studies and needle electromyography, should corroborate the clinical diagnosis and must be done before consideration of any surgical treatment. Conservative care includes rest, modified activities, splinting at wrist and elbow, physical therapy, antiinflammatory drug therapy, and corticosteroid injections...
August 2015: Physical Medicine and Rehabilitation Clinics of North America
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