keyword
MENU ▼
Read by QxMD icon Read
search

Serology

keyword
https://www.readbyqxmd.com/read/28920810/newly-described-toxoplasma-gondii-strain-causes-high-mortality-in-red-necked-wallabies-macropus-rufogriseus-in-a-zoo
#1
Amanda Guthrie, Leah Rooker, Rommel Tan, Richard Gerhold, Karen Trainor, Tiantian Jiang, Chunlei Su
This manuscript describes an outbreak of fatal toxoplasmosis in wallabies. Ten adult red necked wallabies (Macropus rufogriseus) were imported from New Zealand to the Virginia Zoo. Agglutination testing upon admission into quarantine showed all animals to be negative for antibodies to Toxoplasma gondii. Nine of these wallabies died from acute toxoplasmosis within 59-565 (average 224) days after being moved onto exhibit. Clinical signs included lethargy, diarrhea, tachypnea, and ataxia that progressed rapidly; death without premonitory signs occurred in one case...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920800/cutaneous-t-cell-lymphoma-with-lymph-node-metastasis-in-an-adult-addax-addax-nasomaculatus
#2
Zoltan S Gyimesi, Roy B Burns, Sheryl Coutermarsh-Ott, Chris A Schiller, Rita McManamon
A 13-yr-old male addax (Addax nasomaculatus) presented with locally extensive alopecia, slight erythema, and skin thickening on the medial aspect of the left rear leg between the stifle and tarsus. Cutaneous T-cell lymphoma was diagnosed after histopathology and immunohistochemical staining of representative skin-punch biopsies. No treatment was elected, and the addax was euthanized 3 yr later because of poor body condition, chronic dental disease, and confirmed spread of lymphoma to other cutaneous locations...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920784/treatment-success-in-three-andean-bears-tremarctos-ornatus-with-alopecia-syndrome-using-oclacitinib-maleate-apoquel%C3%A2
#3
Gabby J Drake, Tim Nuttall, Javier López, William Magnone, Antoine Leclerc, Romain Potier, Alexis Lécu, Maëlle Guézénec, Lydia Kolter, Amélie Nicolau, Karin Lemberger, Didier Pin, Sallie B Cosgrove
Andean bear (Tremarctos ornatus) alopecia syndrome (ABAS) commonly affects captive bears, particularly sexually mature females. ABAS is characterized by bilaterally symmetrical predominantly flank alopecia with or without profound pruritus and secondary bacterial and Malassezia infections. There is no effective treatment and severely affected bears have been euthanized. This paper describes the successful management of ABAS in three female Andean bears. Skin biopsies and cytology revealed a mixed dermal inflammatory infiltrate, alopecia, hyperkeratosis, and Malassezia dermatitis...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920498/an-update-on-biomarker-discovery-and-use-in-axial-spondyloarthritis
#4
Walter P Maksymowych
Evaluation of diagnosis, disease activity, and risk for joint damage all represent important unmet clinical needs in the management of axial spondyloarthritis that have been explored using biomarkers. Areas Covered: This review used the search terms biomarkers, ankylosing spondylitis, spondyloarthritis, spondyloarthropathy, pathogenesis, genetics, diagnostic tools, prognosis, to explore advances in biomarker development relevant to unmet clinical needs. Expert Commentary: Despite major advances in the identification of genetic risk markers, HLA-B*27 remains the only marker with clinical utility for diagnostic purposes...
September 16, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28920482/fowl-aviadenovirus-serotype-1-confirmed-as-the-aetiological-agent-of-gizzard-erosions-in-replacement-pullets-and-layer-flocks-in-great-britain-by-laboratory-and-in-vivo-studies
#5
Beatrice Grafl, Cristina Garcia-Rueda, Peter Cargill, Alisdair Wood, Alex Schock, Dieter Liebhart, Anna Schachner, Michael Hess
An investigation into the aetiology and pathogenesis of adenoviral gizzard erosion has been conducted following three natural outbreaks affecting one flock of 6-week-old replacement pullets and two consecutive placements of free range layers at the age of 21 and 23 weeks. Affected flocks showed increased mortality (0.12-0.30% per week), and gizzard lesions were consistent with fowl aviadenovirus (FAdV) involvement. To substantiate the initial findings, a selection of archived formalin-fixed paraffin-embedded gizzard samples from another 12 pullet and layer flocks, for which macroscopic and histopathological diagnosis of the disease were recorded in Great Britain during the period 2009-2016, were also investigated...
September 18, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28919997/increased-infiltration-and-tolerised-antigen-specific-cd8-tem-cells-in-tumor-but-not-peripheral-blood-have-no-impact-on-survival-of-hcmv-glioblastoma-patients
#6
M Bahador, A Gras Navarro, M A Rahman, M Dominguez-Valentin, S Sarowar, E Ulvestad, G Njølstad, S A Lie, E K Kristoffersen, E Bratland, M Chekenya
Human cytomegalovirus (HCMV) antigens in glioblastoma (GBM) present opportunities for personalised immunotherapy. However, their presence in GBM tissue is still under debate, and evidence of their impact on functional immune responses and prognosis is sparse. Here, we investigated the presence of pp65 (UL83) and immediate early 1 (IE-1) HCMV antigens in a cohort of Norwegian GBM patients (n = 177), using qPCR, immunohistochemistry, and serology. HCMV status was then used to investigate whether viral antigens influenced immune cell phenotype, infiltration, activation and patient survival...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28919697/16s-ribosomal-rna-sequencing-and-molecular-serotyping-of-avibacterium-paragallinarum-isolated-from-indian-field-conditions
#7
Vihang Vithalrao Patil, Debendranath Mishra, Dilip Vithalrao Mane
AIM: This study was aimed at identifying Indian field isolates of Avibacterium paragallinarum on both molecular as well as serological levels that cause infectious coryza in chickens. MATERIALS AND METHODS: Species-specific polymerase chain reaction (HPG-2 PCR), and 16S ribosomal RNA (rRNA) sequencing were employed for molecular identification. Whereas, multiplex PCR technique was used for serological identification of Indian field isolates of A. paragallinarum...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28919226/validation-of-hav-biomarker-2a-for-differential-diagnostic-of-hepatitis-a-infected-and-vaccinated-individuals-using-multiplex-serology
#8
Katrin Bohm, Angela Filomena, Nicole Schneiderhan-Marra, Gérard Krause, Claudia Sievers
BACKGROUND: Worldwide about 1.5 million clinical cases of hepatitis A virus (HAV) infections occur every year and increasingly countries are introducing HAV vaccination into the childhood immunization schedule with a single dose instead of the originally licenced two dose regimen. Diagnosis of acute HAV infection is determined serologically by anti-HAV-IgM detection using ELISA. Additionally anti-HAV-IgG can become positive during the early phase of symptoms, but remains detectable after infection and also after vaccination against HAV...
September 14, 2017: Vaccine
https://www.readbyqxmd.com/read/28918831/a-comparative-analysis-of-serum-igg4-levels-in-patients-with-igg4-related-disease-and-other-disorders
#9
Li Wang, Xinmin Chu, Yan Ma, Min Zhang, Xue Wang, Li Jin, Zhen Tan, Xiangpei Li, Xiaomei Li
OBJECTIVE: Elevated serum IgG4 levels are an important hallmark for diagnosing IgG4-related disease (IgG4-RD) but can also be found and reported in other diseases. The present study intended to compare the serum IgG4 levels in both IgG4-RD and non-IgG4-RD and determine the serum IgG4 levels in patients with IgG4-RD before and after glucocorticoid therapy. METHODS: The study included 323 patients from Anhui Medical University Affiliated Provincial Hospital (China) and was conducted from July 2014-January 2016...
September 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28918772/incidence-and-risk-factors-for-dengue-virus-denv-infection-in-the-first-2-years-of-life-in-a-brazilian-prospective-birth-cohort
#10
P M S Castanha, U R Montarroyos, S M M Silveira, G D M Albuquerque, M J G Mello, K G S Lopes, M T Cordeiro, E T A Marques, C M T Martelli, C Braga
This study assessed the incidence and risk factors for dengue virus (DENV) infection among children in a prospective birth cohort conducted in the city of Recife, a hyperendemic dengue area in Northeast Brazil. Healthy pregnant women (n = 415) residing in Recife who agreed to have their children followed were enrolled. Children were followed during their first 24 months of age (May/2011-June/2014), before the 2015 Zika virus outbreak. DENV infection was detected by reverse-transcriptase polymerase chain reaction and/or serology (anti-DENV IgM/IgG)...
September 18, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28918638/a-rapid-blood-test-to-determine-the-active-status-and-duration-of-acute-viral-infection
#11
Tianyu Zheng, Caroline Finn, Christopher Parrett, Kunal Dhume, Ji Hae Hwang, David Sidhom, Tara Strutt, Yuen Yee Li Sip, Karl McKinstry, Qun Huo
The ability to rapidly detect and diagnose acute viral infections is crucial for infectious disease control and management. Serology testing for the presence of virus-elicited antibodies in blood is one of the methods used commonly for clinical diagnosis of viral infections. However, standard serology-based tests have a significant limitation: they cannot easily distinguish active from past, historical infections. As a result, it is difficult to determine whether a patient is currently infected with a virus or not, and on an optimal course of action, based off of positive serology testing responses...
September 17, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/28918558/colorimetric-detection-of-unamplified-rift-valley-fever-virus-genetic-material-using-unmodified-gold-nanoparticles
#12
Mostafa R Zaher, Hanaa A Ahmed, Kareem E Z Hamada, Reham H Tammam
Rift Valley fever virus (RVFV) is considered an enzootic virus in Africa. RVFV has caused several outbreaks in Egypt, sub-Saharan Africa and the Arabian Peninsula and is responsible for high mortality in ruminants and haemorrhagic fever in severe human cases. Although there are several molecular and serological diagnostic techniques used to detect this arthropod-borne virus with high sensitivity and efficiency, there is a need for a fast and reliable field screening test for rapid outbreak recording and containment...
September 16, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28918513/imaging-findings-of-primary-immunoglobulin-g4-related-cervical-lymphadenopathy
#13
Masaya Kawaguchi, Hiroki Kato, Yusuke Kito, Keisuke Mizuta, Mitsuhiro Aoki, Keizo Kato, Satoshi Goshima, Masayuki Matsuo
PURPOSE: The purpose of the present study was to assess imaging findings of primary immunoglobulin G4 (IgG4)-related cervical lymphadenopathy. METHODS: Five consecutive patients with clinically, serologically, and histopathologically confirmed primary IgG4-related cervical lymphadenopathy without any other organ involvement were included. All patients underwent contrast-enhanced computed tomography (CT), and four underwent (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/CT...
September 16, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28918478/an-ibero-american-inter-laboratory-trial-to-evaluate-serological-tests-for-the-detection-of-anti-neospora-caninum-antibodies-in-cattle
#14
Lucía M Campero, Javier Moreno-Gonzalo, María C Venturini, Gastón Moré, Andrea Dellarupe, Magdalena Rambeaud, Ignacio E Echaide, Beatriz Valentini, Carlos M Campero, Dadín P Moore, Dora B Cano, Marcelo Fort, Rinaldo A Mota, Marcos E Serrano-Martínez, Carlos Cruz-Vázquez, Luis M Ortega-Mora, Gema Álvarez-García
We carried out an inter-laboratory trial to compare the serological tests commonly used for the detection of specific Neospora caninum antibodies in cattle in Ibero-American countries. A total of eight laboratories participated from the following countries: Argentina (n = 4), Brazil (n = 1), Peru (n = 1), Mexico (n = 1), and Spain (n = 1). A blind panel of well-characterized cattle sera (n = 143) and sera representative of the target population (n = 351) was tested by seven in-house indirect fluorescent antibody tests (IFATs 1-7) and three enzyme-linked immunosorbent assays (ELISAs 1-3; two in-house and one commercial)...
September 16, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28918235/identification-of-bluetongue-virus-serotypes-1-4-and-17-co-infections-in-sheep-flocks-during-outbreaks-in-brazil
#15
Lorena Lima Barbosa Guimarães, Júlio César Câmara Rosa, Ana Carolina Diniz Matos, Raquel Aparecida S Cruz, Maria Isabel Maldonado Coelho Guedes, Fernanda Alves Dorella, Henrique César Pereira Figueiredo, Saulo Petinatti Pavarini, Luciana Sonne, Zélia Inês Portela Lobato, David Driemeier
Bluetongue (BT) is a vector-borne viral disease caused by the Bluetongue virus (BTV), an Orbivirus from the Reoviridae family, affecting domestic and wild ruminants. BTV circulation in Brazil was first reported in 1978, and several serological surveys indicate that the virus is widespread, although with varied prevalence. In 2014, BT outbreaks affected sheep flocks in Rio Grande do Sul state, causing significant mortality (18.4%; 91/495) in BTV-infected sheep. In total, seven farms were monitored, and one or two sheep from each farm that died due to clinical signs of BT were necropsied...
September 5, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28918127/clinical-laboratory-and-virological-data-from-suspected-zikv-patients-in-an-endemic-arbovirus-area
#16
Tatiana Elias Colombo, Cássia Fernanda Estofolete, Andréia Francesli Negri Reis, Natal Santos da Silva, Morgana Lima Aguiar, Eliana Márcia Sotello Cabrera, Izalco Nuremberg Penha Dos Santos, Fabiana Rodrigues Costa, Lilian Elisa Arão Antônio Cruz, Patrícia Lopes Rombola, Ana Carolina Bernardes Terzian, Maurício Lacerda Nogueira
BACKGROUND: The emergence of Zika virus (ZIKV) presents new challenges to both clinicians and public health authorities. Overlapping clinical features between the diseases caused by ZIKV, dengue (DENV) and chikungunya (CHIKV) and the lack of validated serological assays for ZIKV make accurate diagnosis difficult. Brazilian authorities largely rely on clinical and epidemiological data for the epidemiological and clinical classifications of most ZIKV cases. OBJECTIVE: To report the laboratory and clinical profiles of patients diagnosed with Zika fever based only on clinical and epidemiological data...
September 9, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28917322/high-genetic-diversity-in-toxoplasma-gondii-isolates-from-pigs-at-slaughterhouses-in-para%C3%A3-ba-state-northeastern-brazil-circulation-of-new-genotypes-and-brazilian-clonal-lineages
#17
Thais Ferreira Feitosa, Vinícius Longo Ribeiro Vilela, João Leite de Almeida-Neto, Antonielson Dos Santos, Dayana Firmino de Morais, Bruna Farias Alves, Fabiana Nakashima, Solange Maria Gennari, Ana Célia Rodrigues Athayde, Hilda Fátima Jesus Pena
The consumption of raw or undercooked pig meat containing Toxoplasma gondii cysts is an important transmission route of this protozoon to animals and humans. This study aimed to serologically diagnose, isolate and genotype T. gondii from pigs slaughtered for human consumption in the state of Paraíba, northeastern Brazil. Blood and tissue samples (heart, tongue and brain) were collected from 120 pigs at slaughterhouses in the state of Paraíba. Serological examinations were performed with an indirect immunofluorescent antibody test (IFAT) with a cut-off point of 1:64...
September 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28916759/influenza-d-in-italy-towards-a-better-understanding-of-an-emerging-viral-infection-in-swine
#18
Emanuela Foni, Chiara Chiapponi, Laura Baioni, Irene Zanni, Marianna Merenda, Carlo Rosignoli, Constantinos S Kyriakis, Mario Vittorio Luini, Maria Lucia Mandola, Luca Bolzoni, Arrigo Daniele Nigrelli, Silvia Faccini
Influenza D virus (IDV), a new member of the Orthomyxoviridae family, was first reported in 2011 in swine in Oklahoma, and consequently found in cattle across North America and Eurasia. To investigate the circulation of IDV among pigs in Italy, in the period between June 2015 and May 2016, biomolecular and virological tests were performed on 845 clinical samples collected from 448 pig farms affected by respiratory distress located in the Po Valley. Serological tests were conducted on 3698 swine sera, including archive sera collected in 2009, as well as samples collected in 2015 from the same region...
September 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28916545/serologic-evidence-of-gut-driven-systemic-inflammation-in-juvenile-idiopathic-arthritis
#19
Lampros Fotis, Nurmohammad Shaikh, Kevin W Baszis, Charles M Samson, Raffi Lev-Tzion, Anthony R French, Phillip I Tarr
OBJECTIVE: Accumulating evidence links juvenile idiopathic arthritis (JIA) to nonhost factors such as gut microbes. We hypothesize that children with new-onset JIA have increased intestinal bacterial translocation and circulating lipopolysaccharide (LPS). METHODS: We studied systemic treatment-naive patients with JIA [polyarticular JIA, n = 22, oligoarticular JIA, n = 31, and spondyloarthropathies (SpA), n = 16], patients with established inflammatory bowel disease-related arthritis (IBD-RA, n = 11), and 34 healthy controls...
September 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28916316/the-brucella-melitensis-m5-90%C3%AE-manb-live-vaccine-candidate-is-safer-than-m5-90-and-confers-protection-against-wild-type-challenge-in-balb-c-mice
#20
Junbo Zhang, Shuanghong Yin, Dewu Yi, Hong Zhang, Zhiqiang Li, Fei Guo, Chuangfu Chen, Weihuan Fang, Jiafu Wang
Brucellosis is a globally distributed zoonotic disease that causes animal and human diseases. Although effective, the current Brucella vaccines (strain M5-90 or others) have several drawbacks. The first is their residual virulence for animals and humans and the second is their inability to differentiate natural infection from that caused by vaccination. In the present study, Brucella melitensis M5-90 manB mutant (M5-90ΔmanB) was generated to overcome these drawbacks. M5-90ΔmanB showed significantly reduced survival in macrophages and mice, and induced strong protective immunity in BALB/c mice...
September 12, 2017: Microbial Pathogenesis
keyword
keyword
73257
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"