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https://www.readbyqxmd.com/read/28551939/-is-there-a-way-to-reduce-iron-deficiency-anemia-rates-in-the-second-year-of-life-of-bedouin-children-in-the-negev
#1
Orly Kerub, Hillel Vardi, Boris Knyazer, Natalya Bilenko
INTRODUCTION: Iron deficiency anemia is the most common worldwide nutritional deficiency contributing to childhood morbidity and mortality. According to the official health policy in Israel, providing iron for all babies from the age of 4 months to the age of one year old is recommended. This policy also recommends providing iron supplementation for an additional 6 months for toddlers (who are one year old) with anemia (hemoglobin<11mg/dl). Despite this policy, there is still a high rate of anemia in the Negev's two year old children, especially in the Bedouin population...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551935/-comparison-of-quality-of-colonoscopy-in-an-academic-hospital-vs-a-community-hospital-outpatient-service
#2
Badira Makhoul, Muhammad Khatib, Dana Ben Hur, Jesse Lachter
BACKGROUND: Extensive use of colonoscopy in hospitals and community clinics has highlighted the need to assess the quality of the procedures in order to reduce costs and increase their efficiency. OBJECTIVES: This institutional review board (IRB)-approved study aimed to compare the quality of colonoscopies performed in a teaching hospital to those performed at a community health service. METHODS: Demographic information, time of procedure, indications, quality of bowel preparation, premedication, depth of examination, polyp detection, biopsies and followup recommendations were retrospectively obtained from 700 colonoscopy reports from the Rambam Healthcare Campus and 824 colonoscopy reports from Elisha...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551929/-early-in-hospital-mortality-in-internal-medicine-wards-within-24-hours-a-potential-quality-indicator-or-a-variable-affected-by-multiple-factors
#3
Yaron Niv, Evgeny Berkov, Pazit Kanter, Evgeny Abrahmson, Uri Gabbay
AIMS: To evaluate in-hospital mortality rate within 24 hours in internal medicine wards and to evaluate if it may be used as quality indicator. BACKGROUND: In-hospital mortality rate is an outcome measure which apparently reflects quality of care. There are debates on whether it may be considered a quality indicator since it is difficult to compare different case-mixes between hospitals. Research on mortality within 24 hours had not been published. METHODS: An historical prospective study was conducted including the entire internal wards admissions to the Rabin Medical Center between 1/7/14 and 30/6/15...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28551923/-extracorporeal-membrane-oxygenation-in-israel-6-5-years-of-experience-at-the-largest-ecmo-treatment-center-in-israel
#4
Philip Biderman, Uri Carmi, Michael Fainblut, Oren Bachar, Benny Medallion, Dan Aravot
AIMS: The primary purpose of the study is to evaluate the characteristics of the population treated with ECMO at Beilinson Hospital, the treatment results and a comparison of results with ECMO centers in the world. The treatment outcomes relative to the experience of the team during the years 2008-2014 were also examined. The secondary purpose of this article is to increase the awareness of the medical staff to ECMO as a treatment option for patients with appropriate indications, where indications have increased in recent years...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28551913/-dynamic-changes-of-d-dimer-following-stroke
#5
Lihi Shapir, Bella Gross
AIMS: To find the correlation between plasma D-dimer levels after stroke with different etiologies, severity of the stroke and to uncover whether plasma D-dimer levels may be used as a prognostic factor of stroke complication. BACKGROUND: D-dimer is a product of fibrin degradation and it is elevated in systemic vascular events. The association between plasma D-dimer levels and stroke remain uncertain. METHODS: A total of 96 acute stroke patients were enrolled in this study...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551910/-level-and-oxidation-of-beta-2-microglobulin-in-hemodialysis-patients-treated-with-intravenous-iron-during-dialysis-with-high-flux-compared-to-low-flux-dialyzers
#6
Regina Michelis, Shifra Sela, Alexander Lanzmann, Olga Tanchilevski, Revital Shurtz-Swirski, Batya Kristal
INTRODUCTION: Serum levels of β2-microglobulin (b2M) are significantly higher in patients with end stage renal failure undergoing hemodialysis (HD) and its accumulation accelerates Dialysis Related Amyloidosis (DRA). In HD patients low-flux dialysis, intravenous (IV) iron (administered for the treatment of anemia) affects ß2M removal during dialysis. IV iron also affects the oxidation of plasma proteins, including b2M. AIMS: To examine the effect of intravenous iron therapy on ß2M levels and oxidation in HD patients treated with high-flux compared with low-flux dialyzers...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551908/-involvement-of-epigenetic-regulation-in-cerebral-cell-death-following-traumatic-brain-injury-in-a-rat-model
#7
Mona Shehadeh, Moti Ben-Shabat, Jana Livshits, Eilam Palzur
INTRODUCTION: Traumatic brain injuries (TBI) are a major cause of mortality and disability among young adults. TBI are characterized by primary injury, the result of a mechanical impact to the cranium and a secondary injury, a series of molecular mechanism processes developing thereafter. Cerebral cells modify their gene and protein expression as a result of the injury. Epigenetic modifications have a key role as regulators of gene transcription and may simultaneously be involved in the regulation of the molecular pathways following TBI...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551903/-against-all-odds-promoting-research-clinical-development-and-medical-services-of-the-conflict-in-the-galilee-medical-center
#8
Jacob Bornstein
The Galilee Medical Center (GMC) is unique in several aspects. Firstly, in the clinical aspect: In recent years, led by the Director of Medical Center, Dr. Masad Barhoum, a considerable momentum of development has taken place to reduce health discrepancies between the center and the periphery. Despite the under- financing of the health system in the Galilee, the GMC opened new clinical departments, introduced advanced medical technology and key staff members were added. This approach is depicted in publications presented in the current issue...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551885/public-engagement-on-urban-air-pollution-an-exploratory-study-of-two-interventions
#9
Christian Oltra, Roser Sala, Àlex Boso, Sergi López Asensio
The use of portable sensors to measure air quality is a promising approach for the management of urban air quality given its potential to improve public participation in environmental issues and to promote healthy behaviors. However, not all the projects that use air quality mobile sensors consider the potential effects of their use on the attitudes and behaviors of non-expert individuals. This study explores the experiences, perceptions, attitudes, and behavioral intentions of 12 participants who used a real-time NO2 sensor over a period of 7 days in the metropolitan area of Barcelona and compares them with 16 participants who did not have access to the device but rather to documentary information...
June 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28551869/impact-of-chronic-stress-on-the-spatial-learning-and-gr-pkac-nf-%C3%AE%C2%BAb-signaling-in-the-hippocampus-and-cortex-in-rats-following-cholinergic-depletion
#10
Sun-Young Lee, Woo-Hyun Cho, Yo-Seob Lee, Jung-Soo Han
Studies have shown that the removal of the cholinergic innervation to the hippocampus induces dysfunction of the hypothalamic-pituitary-adrenocortical axis and decreases the number of glucocorticoid receptors (GRs). Subsequent studies have revealed that the loss of cholinergic input to the hippocampus reduces the expression of GRs and activates nuclear factor-kappa B (NF-κB) signaling through interactions with the cytoplasmic catalytic subunit of protein kinase A (PKAc). We examined the effects of chronic stress on cognitive status and GR-PKAc-NF-κB signaling in rats with a loss of cholinergic input to the hippocampus and cortex...
May 27, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28551868/light-harvesting-complexes-of-botryococcus-braunii
#11
Tomas E van den Berg, Bart van Oort, Roberta Croce
The colonial green alga Botryococcus braunii (BB) is a potential source of biofuel due to its natural high hydrocarbon content. Unfortunately, its slow growth limits its biotechnological potential. Understanding its photosynthetic machinery could help to identify possible growth limitations. Here, we present the first study on BB light-harvesting complexes (LHCs). We purified two LHC fractions containing the complexes in monomeric and trimeric form. Both fractions contained at least two proteins with molecular weight (MW) around 25 kDa...
May 27, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28551862/delivery-of-community-based-care-through-inter-professional-teams-in-brazil-s-unified-health-system-uhs-comparing-perceptions-across-community-health-agents-chas-nurses-and-physicians
#12
Rahbel Rahman, Rogério Meireles Pinto, Margareth Santos Zanchetta, Melanie M Wall
Given the shortage of medical providers and the need for medical decisions to be responsive to community needs, including lay health providers in health teams has been recommended as essential for the successful management of global health care systems. Brazil's Unified Health System (UHS) is a model for delivering community-based care through Family Health Strategy (FHS) interdisciplinary teams comprised of medical and lay health providers-Community Health Agents (CHAs), nurses, and physicians. This study aims to understand how medical and lay health providers' perceptions and attitudes could impact the delivery of community-based care...
May 27, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28551859/cognitive-workload-reduction-in-hospital-information-systems-decision-support-for-order-set-optimization
#13
Daniel Gartner, Yiye Zhang, Rema Padman
Order sets are a critical component in hospital information systems that are expected to substantially reduce physicians' physical and cognitive workload and improve patient safety. Order sets represent time interval-clustered order items, such as medications prescribed at hospital admission, that are administered to patients during their hospital stay. In this paper, we develop a mathematical programming model and an exact and a heuristic solution procedure with the objective of minimizing physicians' cognitive workload associated with prescribing order sets...
May 27, 2017: Health Care Management Science
https://www.readbyqxmd.com/read/28551858/cost-effectiveness-of-drug-treatments-for-advanced-melanoma-a-systematic-literature-review
#14
REVIEW
Darío Rubio-Rodríguez, Silvia De Diego Blanco, Maite Pérez, Carlos Rubio-Terrés
BACKGROUND: Until recently, advanced melanoma (unresectable and metastatic) has had a poor prognosis and has been treated with chemotherapy. The introduction of new treatments (BRAF and MEK inhibitors and immunotherapy) has improved overall survival and progression-free survival of some patients. OBJECTIVE: The objective of this study was to review the published evidence on the cost-effectiveness of pharmacological treatments for advanced melanoma. METHODS: A systematic literature search was conducted, without date or language restrictions, in PubMed, EMBASE, Scopus, the Cochrane Library, the UK National Institute for Health and Care Excellence databases and the Health Technology Assessment journal...
May 27, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28551855/characterization-of-a-novel-theme-c-glycoside-hydrolase-family-9-cellulase-and-its-cbm-chimeric-enzymes
#15
Cheng-Jie Duan, Ming-Yue Huang, Hao Pang, Jing Zhao, Chao-Xing Wu, Jia-Xun Feng
In bacterial cellulase systems, glycoside hydrolase family 9 (GH9) cellulases are generally regarded as the major cellulose-degrading factors besides GH48 exoglucanase. In this study, umcel9A, which was cloned from uncultured microorganisms from compost, with the encoded protein being theme C GH9 cellulase, was heterologously expressed in Escherichia coli, and the biochemical properties of the purified enzyme were characterized. Hydrolysis of carboxylmethylcellulose (CMC) by Umcel9A led to the decreased viscosity of CMC solution and production of reducing sugars...
May 27, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28551852/cultivable-microscopic-fungi-from-an-underground-chemosynthesis-based-ecosystem-a-preliminary-study
#16
Alena Nováková, Vít Hubka, Šárka Valinová, Miroslav Kolařík, Alexandra Maria Hillebrand-Voiculescu
Movile Cave, a unique groundwater ecosystem in southern Romania, was discovered in 1986. This chemoautotrophic cave contains an abundant and diverse fauna with terrestrial and aquatic invertebrate communities, including 33 endemic species. Since its discovery, studies have focused mainly on cave chemoautotrophic bacteria, while the microfungal community has been largely neglected. In this study, we determined the microfungal species living on various substrates in Movile Cave and compared this spectrum with the mycobiota detected outside the cave (outside air-borne and soil-borne microfungi)...
May 28, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28551848/mri-features-of-pediatric-intracranial-germ-cell-tumor-subtypes
#17
Chih-Chun Wu, Wan-Yuo Guo, Feng-Chi Chang, Chao-Bao Luo, Han-Jui Lee, Yi-Wei Chen, Yi-Yen Lee, Tai-Tong Wong
Intracranial germ cell tumors differ in histology and location, and require different clinical management strategies. We characterized the imaging features that may aid pre-operative differentiation of intracranial germinomas and non-germinomatous germ cell tumors (NGGCTs). This retrospective study analyzed 85 patients with intracranial germ cell tumors and adequate preoperative or pretreatment MRIs between 2000 and 2013 at our institution. Pretreatment MRI characteristics, apparent diffusion coefficient (ADC) values, tumor histopathology, and patient outcomes were compared...
May 27, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28551847/prior-malignancies-in-patients-harboring-glioblastoma-an-institutional-case-study-of-2164-patients
#18
REVIEW
Brad E Zacharia, Natalie DiStefano, Marius M Mader, Muhammad O Chohan, Shahiba Ogilvie, Cameron Brennan, Philip Gutin, Viviane Tabar
More patients are surviving long-term following a cancer diagnosis and as such are at risk for second malignancies. As the most common primary brain tumor, glioblastoma (GBM) will not infrequently occur in this population. No study has examined the incidence of prior cancer (PC) in patients harboring GBM. Here we evaluate the epidemiological features, as well as the molecular and clinical characteristics of GBM as a second cancer. Utilizing a web-based cancer data management system at our institution, we identified 2164 patients harboring GBM from 2007 to 2014...
May 27, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28551840/pregnancy-after-endometrial-scratching-in-infertile-couples-undergoing-ovulation-induction-and-intrauterine-insemination-cycles-a-randomized-controlled-trial
#19
Tuhina Goel, Reeta Mahey, Neerja Bhatla, Mani Kalaivani, Sangeeta Pant, Alka Kriplani
PURPOSE: To study the effect of endometrial scratching in infertile couples undergoing ovulation induction and intrauterine insemination (IUI) cycles. METHODS: A prospective randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology, AIIMS, New Delhi, India. One hundred forty-four women with primary/secondary infertility were recruited. Couples were either unexplained or male factor infertility. Subjects were randomized into intervention (scratching) and control group...
May 27, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28551836/does-exercise-training-augment-improvements-in-quality-of-life-induced-by-energy-restriction-for-obese-populations-a-systematic-review
#20
REVIEW
Daniel J van den Hoek, Clint T Miller, Steve F Fraser, Steve E Selig, John B Dixon
OBJECTIVE: Obesity is associated with a decline in health-related quality of life (HRQOL), while weight loss and exercise training have a positive influence. The aim of this systematic review was to compare the effects of energy restriction (ER) alone intervention to diet and exercise intervention on HRQOL. METHODS: MEDLINE, CINAHL and PsycINFO databases were searched for randomised controlled trials examining HRQOL through lifestyle interventions which examined ER and energy restriction plus exercise in obese adults...
May 27, 2017: Quality of Life Research
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