keyword
MENU ▼
Read by QxMD icon Read
search

comparative study

keyword
https://www.readbyqxmd.com/read/29149783/hematological-improvement-of-patients-with-active-rheumatoid-arthritis-by-%C3%AE-d-mannuronic-acid-m2000-as-a-novel-nsaid-with-immunosuppressive-property
#1
Hossein Ahmadi, Ahmad Reza Jamshidi, Mahdi Mahmoudi, Farhad Gharibdoost, Mahdi Vojdanian, Mohammad Javad Fattahi, Noushin Rastkari, Zahra Aghazadeh, Abbas Mirshafiey
The aim of this study was to investigate the effect of β-D-mannuronic acid (M2000) on hematological parameters in patients with active rheumatoid arthritis. This study was conducted on 25 patients with active rheumatoid arthritis (RA) (identifier: IRCT2014011213739N2). M2000 was administered orally for anemic and non-anemic RA patients at a dose of 500 mg twice daily for 12 weeks. The patients were permitted to continue the conventional treatments excluding NSAIDs. Blood samples were collected at baseline, 4 and 12 weeks after drug administration and were tested for hematological parameters...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149782/frequency-of-circulatory-regulatory-immune-cells-in-iranian-patients-with-type-1-diabetes
#2
Tahereh Khamehchian, Eqlim Nemati, Marziyeh Jazayeri, Shirin Azimi, Hassan Nikoueinejad, Hossein Akbari, Behnaz Irandoust
Type 1 diabetes (T1D) is the result of the autoimmune destruction of insulin-producing beta cells. Regulatory T cells (Tregs) and plasmacytoid dendritic cells (PDCs) act as mediators of peripheral tolerance. We investigated the possible alterations of such cells in peripheral blood of patients with T1D compared to normal individuals. This comparison may lead to a better understanding of the immunopathogenesis processes involved in T1D. 92 participants, including 49 patients with T1D and 43 healthy controls were studied...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149781/macrophages-from-behcet-s-disease-patients-express-decreased-level-of-aryl-hydrocarbon-receptor-ahr-mrna
#3
Mohammad Taghi Palizgir, Maryam Akhtari, Mahdi Mahmoudi, Shayan Mostafaei, Alireza Rezaeimanesh, Massoomeh Akhlaghi, Farhad Shahram
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor, connecting environmental stimulators with the immune system. M1 macrophages are a part of immune system that contribute to the inflammatory events in the pathogenesis of Behcet's disease (BD). The effect of AHR on the macrophages in BD patients is still unclear. In this study, we investigated the mRNA expression of AHR in the monocyte-derived and M1 macrophages in active BD patients in comparison to healthy controls. Isolated monocytes from 10 healthy controls and 10 active BD patients were differentiated to macrophages by macrophage-colony stimulating factor (M-CSF) for 7 days...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149780/interleukin-37-relieves-allergic-inflammation-in-a-house-dust-mite-allergic-rhinitis-murine-model
#4
Do Hyun Kim, Si Won Kim, Soo Whan Kim, Jun-Myung Kang
The purpose of this study was to investigate the effects of interleukin-37 (IL-37) on a Dermatophagoides farinae (Der f)-induced murine model of allergic rhinitis (AR). BALB/c mice, except the control groups, were sensitized intraperitoneally and challenged intranasally with Der f (Der f group). The IL-37 and IL-37+anti-CD25 groups were administered IL-37 intranasally. The IL-37+anti-CD25 groups were administered anti-CD25 monoclonal antibody intraperitoneally before challenge. Allergic symptoms and the average eosinophil number were counted...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149779/increased-genes-expression-levels-of-cytokines-related-to-th17-treg-cells-in-peripheral-blood-mononuclear-cell-correlate-with-clinical-severity-in-copd-and-mustard-gas-exposed-patients
#5
Parisa Farahani, Raheleh Halabian, Ensieh Vahedi, Jafar Salimian
The long lasting inflammation and immune dysregulation is one of the main mechanisms involved in lung complication of veterans exposed to sulfur mustard (SM) gas. Th17/Treg cells have an important role in immunopathogenesis of chronic obstructive pulmonary disease (COPD) and mustard lung disease. In this study, expression of cytokines genes levels related to Th17/Treg cells was determined in peripheral blood mononuclear (PBMC) of mustard lung patients and was compared with COPD patients and healthy controls (HC)...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149776/effect-of-nebulized-3-hypertonic-saline-with-salbutamol-on-management-of-acute-asthma-in-outpatient-adults-a-double-blind-randomized-clinical-trial-in-emergency-department
#6
Arash Forouzan, Kambiz Masoumi, Ali Delirrooyfard, Ali Asgari Darian, Laaya Mokhtar Gandomani
Asthma is one of the most common disorders of respiratory tract, management of which still remains as a serious health problem. This study aimed to compare the efficacy of 3% hypertonic saline (HS) plus salbutamol with solely salbutamol on management of acute adults' asthma based on peak flow meter findings. In this double-blind randomized clinical trial, 340 adult patients with acute asthma attacks admitted to emergency department of Ahvaz Golestan and Emam hospitals were enrolled during 2014-2015. The patients were allocated randomly to intervention group (nebulized 2...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149768/mitochondrial-dna-changes-in-pedunculopontine-cholinergic-neurons-in-parkinson-s
#7
Alexander G Bury, Angela Pyle, Joanna L Elson, Laura Greaves, Christopher M Morris, Gavin Hudson, Ilse S Pienaar
In Parkinson's disease (PD), mitochondrial dysfunction associates with nigral dopaminergic neuronal loss. Cholinergic neuronal loss co-occurs, particularly within a brainstem structure, the pedunculopontine nucleus (PPN). We isolated single cholinergic neurons from post-mortem PPNs of aged controls and PD patients. Mitochondrial DNA (mtDNA) copy number and mtDNA deletions were increased significantly in PD patients compared to controls. Furthermore, compared to controls the PD patients had significantly more PPN cholinergic neurons containing mtDNA deletion levels exceeding 60%, a level associated with deleterious effects on oxidative phosphorylation...
November 17, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29149759/dusp1-alleviates-cardiac-ischemia-reperfusion-injury-by-suppressing-the-mff-required-mitochondrial-fission-and-bnip3-related-mitophagy-via-the-jnk-pathways
#8
Qinhua Jin, Ruibing Li, Nan Hu, Ting Xin, Pingjun Zhu, Shunying Hu, Sai Ma, Hong Zhu, Jun Ren, Hao Zhou
Mitochondrial fission and selective mitochondrial autophagy (mitophagy) form an essential axis of mitochondrial quality control that plays a critical role in the development of cardiac ischemia-reperfusion (IR) injury. However, the precise upstream molecular mechanism of fission/mitophagy remains unclear. Dual-specificity protein phosphatase1 (DUSP1) regulates cardiac metabolism, but its physiological contribution in the reperfused heart, particularly its influence on mitochondrial homeostasis, is unknown. Here, we demonstrated that cardiac DUSP1 was downregulated following acute cardiac IR injury...
November 6, 2017: Redox Biology
https://www.readbyqxmd.com/read/29149758/oligotrophy-as-a-major-driver-of-mercury-bioaccumulation-in-medium-to-high-trophic-level-consumers-a-marine-ecosystem-comparative-study
#9
Tiphaine Chouvelon, Pierre Cresson, Marc Bouchoucha, Christophe Brach-Papa, Paco Bustamante, Sylvette Crochet, Françoise Marco-Miralles, Bastien Thomas, Joël Knoery
Mercury (Hg) is a global contaminant of environmental concern. Numerous factors influencing its bioaccumulation in marine organisms have already been described at both individual and species levels (e.g., size or age, habitat, trophic level). However, few studies have compared the trophic characteristics of ecosystems to explain underlying mechanisms of differences in Hg bioaccumulation and biomagnification among food webs and systems. The present study aimed at investigating the potential primary role of the trophic status of systems on Hg bioaccumulation and biomagnification in temperate marine food webs, as shown by their medium-to high-trophic level consumers...
November 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29149757/comparing-the-screening-property-of-the-shortened-versions-of-the-hypomania-checklist-32-hcl-32-cross-validation-in-korean-patients-with-bipolar-disorder-and-major-depressive-disorder
#10
Bin-Na Kim, Eun-Ho Lee, Hye-Jin Kim, Ji-Hae Kim
BACKGROUND: To date, shortened versions of the Hypomania Checklist-32 (HCL-32) were proposed to overcome the limitation of a lengthy format; however, a cross-validation study is currently needed to identify which shorter version may function optimally in a clinical sample. METHODS: In a Korean patient sample with bipolar disorder (BD) and major depressive disorder (MDD) (BD-I n = 84, BD = II n = 145, MDD n = 285), we examined the reliability and screening property of three shorter versions of the HCL (HCL-20, -16, -8) in comparison with the full HCL-32...
November 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29149754/the-effect-of-comorbid-depression-on-the-use-of-unscheduled-hospital-care-by-people-with-a-long-term-condition-a-retrospective-observational-study
#11
Tom Ricketts, Emily Wood, John Soady, David Saxon, Joe Hulin, Sally Ohlsen, Caroline Mitchell
BACKGROUND: The prevalence of long-term conditions (LTCs) and multiple-morbidity is increasing. Depression prevalence increases with the number of LTCs. Self-management of LTCs improves outcomes, but depression impacts on self-management. Unscheduled hospital care may be a proxy for failure of planned care to support successful self-management. METHODS: Retrospective observational study based on routine NHS datasets covering 19 LTCs. Prevalence of LTCs and depression was identified in all primary care registered adults in one English city (n = 469,368)...
November 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29149750/friends-or-foes-monetized-life-cycle-assessment-and-cost-benefit-analysis-of-the-site-remediation-of-a-former-gas-plant
#12
Lies Huysegoms, Sandra Rousseau, Valérie Cappuyns
Site contamination is a global concern because of the potential risks for human health and ecosystem quality. Every contaminated site has its own specific characteristics and the increased availability and efficiency of remediation techniques makes the choice of remediation alternative increasingly complicated. In this paper an attributional Life Cycle Assessment (LCA) of the secondary environmental impacts of a site remediation is performed and its results are monetized using two different monetization techniques, namely Stepwise 2006 and Ecovalue 08...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149745/household-air-pollution-and-chronic-hypoxia-in-the-placenta-of-pregnant-nigerian-women-a-randomized-controlled-ethanol-cookstove-intervention
#13
Anindita Dutta, Galina Khramstova, Katherine Brito, Donee Alexander, Ariel Mueller, Sireesha Chinthala, Damilola Adu, Tope Ibigbami, John Olamijulo, Abayomi Odetunde, Kehinde Adigun, Liese Pruitt, Ian Hurley, Olufunmilayo Olopade, Oladosu Ojengbede, Sarosh Rana, Christopher O Olopade
BACKGROUND: Household air pollution (HAP) is associated with adverse pregnancy outcomes. OBJECTIVES: Investigate impact of in-utero HAP exposure on placental development and chronic hypoxia. METHODS: Markers of chronic placental hypoxia [Hofbauer cells (HBC), syncytial knots (SK), chorionic vascular density (cVD) and hypoxia-inducible factor (HIF)] were stained by hematoxylin-eosin and/or immunohistochemically in placenta samples collected from firewood-/kerosene-users (A,n=16), and ethanol-users (B,n=20) that participated in a randomized controlled intervention trial in Ibadan, Nigeria...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149743/multigenerational-effects-of-salinity-in-six-clonal-lineages-of-daphnia-longispina
#14
C Venâncio, R Ribeiro, A M V M Soares, I Lopes
Sea level rise, as a consequence of climate changes, is already causing seawater intrusion in some freshwater coastal ecosystems worldwide. The increase in salinity at these freshwater coastal ecosystems may occur gradually (through groundwater) or abruptly (through extreme weather events). Moreover, many of them are also being altered and threatened by anthropogenic activities. Accordingly, the present study aimed at assessing the multigenerational lethal and sublethal effects caused by increased salinity in six clonal lineages of the freshwater cladoceran Daphnia longispina differing in their sensitivity to lethal levels of copper...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149742/stability-of-heavy-metals-in-soil-washing-residue-with-and-without-biochar-addition-under-accelerated-ageing
#15
Zhengtao Shen, Deyi Hou, Bin Zhao, Wendi Xu, Yong Sik Ok, Nanthi S Bolan, Daniel S Alessi
Soil washing residue (SWR), which typically concentrates the washed toxic metals and is comprised of high contents of clay particles, may pose risks to the surrounding environment. This study aims to simulate accelerated ageing to assess the stability of selected metals (Cd(2+) (132mg/kg), Cu(2+) (248mg/kg) and Pb(2+) (3470mg/kg)) in a SWR (89.68% of clay) with and without biochar treatment. The soil was incubated under constant moisture and wet-dry cycles (accelerated ageing), respectively, and the mobility and fractions of heavy metals in the soils with and without biochar treatment were examined...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149739/removal-of-tio2-nanoparticles-from-water-by-low-pressure-pilot-plant-filtration
#16
Josune Olabarrieta, Oihane Monzón, Yolanda Belaustegui, Jon-Iñaki Alvarez, Saioa Zorita
Rising use of nanoparticles in manufacturing as well as in commercial products bring issues related to environmental release and human exposure. A large amount of TiO2 nanoparticles will eventually reach wastewater treatment plants. Low pressure membrane filtration has been suggested as a feasible treatment of water streams. This study investigated first at laboratory scale the influence of: i) membrane material, ii) pore size and iii) water chemistry on nTiO2 removal. TiO2 retention was governed by the cake layer formation mechanism and significant retention of nanoparticles was observed even for filters having considerably larger pores than nTiO2...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149737/source-apportionment-of-black-carbon-during-winter-in-beijing
#17
Yue Liu, Caiqing Yan, Mei Zheng
Black carbon (BC) in PM2.5 was measured at an urban site in Beijing during winter 2015 using an aethalometer. The characteristics and sources of BC during pollution episodes and clean days were analyzed. The average hourly mass concentration of BC during the study period was 5.31±6.27μg/m(3). BC was highly correlated with PM2.5 (R(2)=0.80), with its concentration ranging from 0.17μg/m(3) in clean days to 35.33μg/m(3) in haze days. Source apportionment results showed that the average contribution of liquid fuel source (e...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149717/usefulness-of-the-montreal-cognitive-assessment-moca-to-monitor-cognitive-impairments-in-depressed-patients-receiving-electroconvulsive-therapy
#18
Rémi Moirand, Filipe Galvao, Maxime Lecompte, Emmanuel Poulet, Frédéric Haesebaert, Jerome Brunelin
There is a lack of consensual tools for evaluating the cognitive side-effects in patients with depression who are treated with electroconvulsive therapy (ECT). The objective of this study was to evaluate the usefulness of the Montreal Cognitive Assessment (MoCA) and of the Mini Mental State Examination (MMSE) to monitor cognitive changes in patients with depression receiving ECT. Cognitive functioning was assessed prospectively in 48 patients with unipolar or bipolar depression before and after an ECT course...
November 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29149706/exploring-the-impact-of-route-of-administration-on-medication-acceptance-in-hospitalized-patients-implications-for-venous-thromboembolism-prevention
#19
Victor O Popoola, Farrah Tavakoli, Brandyn D Lau, Matthew Lankiewicz, Patricia Ross, Peggy Kraus, Dauryne Shaffer, Deborah B Hobson, Jonathan K Aboagye, Norma A Farrow, Elliott R Haut, Michael B Streiff
BACKGROUND: Non-administration of venous thromboembolism (VTE) prophylaxis contributes to preventable patient harm. We hypothesized that non-administration would be more common for parenteral VTE prophylaxis than oral infectious disease or cardiac prophylaxis or for treatment medications. The primary study goal was to determine if non-administration of parenteral VTE prophylaxis is more frequent than other prophylactic or treatment medications. METHODS: In this retrospective cohort study of consecutive admissions we used descriptive statistics and risk ratios (RR) to compare the number of non-administered doses of VTE prophylaxis, oral infectious disease and cardiovascular prophylaxis and treatment medications...
October 21, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29149700/protective-role-of-biosynthesized-silver-nanoparticles-against-early-blight-disease-in-solanum-lycopersicum
#20
Madhuree Kumari, Shipra Pandey, Arpita Bhattacharya, Aradhana Mishra, C S Nautiyal
Tomato suffers a huge loss every year because of early blight disease. This study focuses on efficient inhibition of Alternaria solani, the causative agent of early blight disease in tomato in vitro and in vivo. Foliar spray of 5 μg/mL of biosynthesized silver nanoparticles in A. solani infected plants resulted in significant increase of 32.58% in fresh weight and 23.52% in total chlorophyll content of tomato as compared to A. solani infected plants. A decrease of 48.57, 30, 39.59 and 28.57% was observed in fungal spore count, lipid peroxidation, proline content and superoxide dismutase respectively in infected tomato plants after treatment with synthesized silver nanoparticles as compared to A...
November 10, 2017: Plant Physiology and Biochemistry: PPB
keyword
keyword
73251
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"