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https://www.readbyqxmd.com/read/28110518/low-rates-of-predominant-breastfeeding-in-hospital-after-gestational-diabetes-particularly-among-indigenous-women-in-australia
#1
Catherine R Chamberlain, Alyce N Wilson, Lisa H Amir, Kerin O'Dea, Sandra Campbell, Dympna Leonard, Rebecca Ritte, Mary Mulcahy, Sandra Eades, Rory Wolfe
OBJECTIVES: To investigate rates of 'any' and 'predominant' breastfeeding in hospital among Indigenous and non-Indigenous women with and without gestational diabetes mellitus (GDM). METHODS: A retrospective study of singleton infants born from July 2007 to December 2010 at Cairns Hospital, Australia, following GDM pregnancy, using linked hospital and birth data (n=617 infants), with a subsample of medical record reviews (n=365 infants). Aggregate data were used to compare to breastfeeding rates among infants born following non-GDM pregnancy (n=7,894 infants)...
January 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28110511/first-examination-of-varying-health-outcomes-of-the-chronically-homeless-according-to-housing-first-configuration
#2
Elizabeth Whittaker, Timothy Dobbins, Wendy Swift, Paul Flatau, Lucinda Burns
OBJECTIVE: To determine whether two Housing First configurations (scattered site [SS] versus congregated site [CS]) are associated with different health-related outcomes. METHODS: This ecological study employed a longitudinal, quantitative design to compare the outcomes from 63 individuals (SS: n=37; CS: n=26) in Sydney, Australia, over 12 months. RESULTS: Both configurations showed similar improvements in quality of life and psychological distress...
January 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28110510/access-equity-and-costs-of-induced-abortion-services-in-australia-a-cross-sectional-study
#3
Mridula Shankar, Kirsten I Black, Philip Goldstone, Safeera Hussainy, Danielle Mazza, Kerry Petersen, Jayne Lucke, Angela Taft
OBJECTIVES: To examine access and equity to induced abortion services in Australia, including factors associated with presenting beyond nine weeks gestation. METHODS: Cross-sectional survey of 2,326 women aged 16+ years attending for an abortion at 14 Dr Marie clinics. Associations with later presentation assessed using multivariate logistic regression. RESULTS: Over a third of eligible women opted for a medical abortion. More than one in 10 (11...
January 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28110508/on-an-enhanced-rank-preserving-structural-failure-time-model-to-handle-treatment-switch-crossover-and-dropout
#4
Lingling Li, Shijie Tang, Liewen Jiang
It is very challenging to estimate the comparative treatment effect between a treatment therapy and a control therapy on overall survival in the presence of treatment crossover, switch to an alternative non-study therapy, and non-random patient dropout. Existing methods (e.g., intent-to-treat and per-protocol) are known to be biased. We proposed two new estimators to address these analytical challenges and evaluated their performance via a comprehensive simulation study. The new estimators were constructed by combining an enhanced rank-preserving structural failure time model and the inverse probability censoring weighting approach...
January 22, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28110507/computer-assisted-quantification-of-cd3-t-cells-in-follicular-lymphoma
#5
Fazly S Abas, Arwa Shana'ah, Beth Christian, Robert Hasserjian, Abner Louissaint, Michael Pennell, Berkman Sahiner, Weijie Chen, Muhammad Khalid Khan Niazi, Gerard Lozanski, Metin Gurcan
The advance of high resolution digital scans of pathology slides allowed development of computer based image analysis algorithms that may help pathologists in IHC stains quantification. While very promising, these methods require further refinement before they are implemented in routine clinical setting. Particularly critical is to evaluate algorithm performance in a setting similar to current clinical practice. In this article, we present a pilot study that evaluates the use of a computerized cell quantification method in the clinical estimation of CD3 positive (CD3+) T cells in follicular lymphoma (FL)...
January 22, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28110494/a-systematic-review-of-cognitive-effects-of-exercise-in-depression
#6
N Brondino, M Rocchetti, L Fusar-Poli, E Codrons, L Correale, M Vandoni, C Barbui, P Politi
OBJECTIVE: The aim of the present systematic review and meta-analysis was to evaluate the impact of physical exercise on cognitive symptoms in depressed adult patients. METHODS: Systematic literature search was performed in Web of Science™ and CINAHL from inception to August 2016. Two reviewers independently selected randomized trials evaluating the effect of exercise on cognitive functions in patients with a validated diagnosis of depression. Outcome measures included global cognition and different cognitive domains (speed of processing, attention/vigilance, working memory, verbal and visual memory, and reasoning)...
January 22, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28110486/spectra-optia-%C3%A2-for-automated-red-blood-cell-exchange-in-patients-with-sickle-cell-disease-a-nice-medical-technology-guidance
#7
REVIEW
Iain Willits, Helen Cole, Roseanne Jones, Kimberley Carter, Mick Arber, Michelle Jenks, Joyce Craig, Andrew Sims
The Spectra Optia(®) automated apheresis system, indicated for red blood cell exchange in people with sickle cell disease, underwent evaluation by the National Institute for Health and Care Excellence, which uses its Medical Technologies Advisory Committee to make recommendations. The company (Terumo Medical Corporation) produced a submission making a case for adoption of its technology, which was critiqued by the Newcastle and York external assessment centre. Thirty retrospective observational studies were identified in their clinical submission...
January 21, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28110485/are-obese-patients-at-an-increased-risk-of-pelvic-floor-dysfunction-compared-to-non-obese-patients
#8
Isaac José Felippe Corrêa Neto, Rodrigo Ambar Pinto, José Marcio Neves Jorge, Marco Aurélio Santo, Leonardo Alfonso Bustamante-Lopez, Ivan Cecconello, Sérgio Carlos Nahas
PURPOSE: Factors associated with increased intra-abdominal pressure such as chronic cough, morbid obesity, and constipation may be related to pelvic floor dysfunction. In this study, we compared anorectal manometry values and clinical data of class II and III morbidly obese patients referred to bariatric surgery with that of non-obese patients. METHODS: We performed a case-matched study between obese patients referred to bariatric surgery and non-obese patients without anorectal complaints...
January 21, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28110482/the-evaluation-of-a-new-marker-of-transmyocardial-repolarization-parameters-in-ischemic-stroke-patients-t-peak-t-end-t-p-e-t-p-e-qtc
#9
Emine Emektar, Şeref Kerem Çorbacıoğlu, Osman Korucu, Selma Ramadan, Hüseyin Uzunosmanoğlu, Eda Kan, Yunsur Çevik
The cardiovascular manifestations of acute ischemic stroke have been well known. Several electrocardiography (ECG) abnormalities have been reported in patients following acute stroke, including QT interval prolongation, ST segment deviation and T-wave changes. This study aimed to investigate the changes in transmyocardial repolarization parameters, in ischemic stroke patients. The study is a prospective, blind, and controlled clinical study. The patients without cardiac disease who received ischemic stroke diagnoses were included in the study...
January 21, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28110481/pregnancy-associated-transient-osteoporosis-of-the-hip-results-of-a-case-control-study
#10
Peyman Hadji, Jelena Boekhoff, Melitta Hahn, Lars Hellmeyer, Olaf Hars, Ioannis Kyvernitakis
: The etiology and underlying mechanisms of transient of osteoporosis of the hip (TOH) during pregnancy are still unclear, since no systematic analyses exist. Our results support the hypothesis that TOH is a multifactorial disease, which is associated with immobility, dental problems, and lack of exercise in childhood. INTRODUCTION: Pregnancy-associated transient osteoporosis of the hip (TOH) is a rare but severe form of osteoporosis, which may affect a subgroup of women in the last trimester of pregnancy or immediately postpartum...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28110480/casubtype-an-r-package-to-identify-gene-sets-predictive-of-cancer-subtypes-and-clinical-outcomes
#11
Hualei Kong, Pan Tong, Xiaodong Zhao, Jielin Sun, Hua Li
In the past decade, molecular classification of cancer has gained high popularity owing to its high predictive power on clinical outcomes as compared with traditional methods commonly used in clinical practice. In particular, using gene expression profiles, recent studies have successfully identified a number of gene sets for the delineation of cancer subtypes that are associated with distinct prognosis. However, identification of such gene sets remains a laborious task due to the lack of tools with flexibility, integration and ease of use...
January 21, 2017: Interdisciplinary Sciences, Computational Life Sciences
https://www.readbyqxmd.com/read/28110472/surgical-denervation-of-specific-cutaneous-nerves-impedes-excisional-wound-healing-of-small-animal-ear-pinnae
#12
Bhagwat V Alapure, Yan Lu, Hongying Peng, Song Hong
Damage to cutaneous nerves inhibits wound healing in patients. Results from animals on the nerve contributions to healing are various and sometimes contradictory. Here, we aim to clearly define the collective role of central, caudal, and rostral nerves in ear wound healing of mice, rats, and rabbits. These wounds heal with minimal contraction like wounds in humans. We resected central, caudal, and rostral nerves at the base of ear pinnae by microsurgery and created excisional full-thickness skin wounds in the pinnae neurologically downstream from the resections...
January 21, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28110468/effects-of-breakfast-eating-and-eating-frequency-on-body-mass-index-and-weight-loss-outcomes-in-adults-enrolled-in-an-obesity-treatment-program
#13
Maureen Megson, Rena Wing, Tricia M Leahey
This study examined the effects of breakfast eating and eating frequency on objectively assessed BMI and weight loss outcomes among adults enrolled in obesity treatment. Participants completed measures of breakfast eating and eating frequency before and after treatment and had their height and weight measured. Baseline breakfast eating and eating frequency were not associated with baseline BMI (p = .34, p = .45, respectively) and did not predict weight loss during treatment (p = .36, p = .58, respectively)...
January 21, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28110459/calcium-phosphate-ceramics-and-polysaccharide-based-hydrogel-scaffolds-combined-with-mesenchymal-stem-cell-differently-support-bone-repair-in-rats
#14
Sophie Frasca, Françoise Norol, Catherine Le Visage, Jean-Marc Collombet, Didier Letourneur, Xavier Holy, Elhadi Sari Ali
Research in bone tissue engineering is focused on the development of alternatives to autologous bone grafts for bone reconstruction. Although multiple stem cell-based products and biomaterials are currently being investigated, comparative studies are rarely achieved to evaluate the most appropriate approach in this context. Here, we aimed to compare different clinically relevant bone tissue engineering methods and evaluated the kinetic repair and the bone healing efficiency supported by mesenchymal stem cells and two different biomaterials, a new hydrogel scaffold and a commercial hydroxyapatite/tricalcium phosphate ceramic, alone or in combination...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28110457/reduced-proliferation-and-colony-formation-of-head-and-neck-squamous-cell-carcinoma-hnscc-after-dual-targeting-of-egfr-and-hedgehog-pathways
#15
Hannes Liebig, Georg Günther, Marlen Kolb, Christian Mozet, Andreas Boehm, Andreas Dietz, Gunnar Wichmann
PURPOSE: The hedgehog signalling pathway (Hh) is frequently active in head and neck squamous cell carcinoma (HNSCC). Overexpressed Hh associates with poor prognosis. The Hh inhibitor vismodegib targets smoothened, and based on molecular data, may prevent resistance to EGFR targeting. METHODS: To elucidate potential roles of vismodegib in HNSCC therapy, its sole effects and those combined with cisplatin, docetaxel, and cetuximab on HNSCC cell lines were assessed by MTT metabolisation and BrdU incorporation...
January 21, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28110451/the-importance-of-various-stages-of-succession-in-preservation-of-biodiversity-among-riparian-birds-in-northern-iran
#16
Zahra Sepehri Roshan, Sina Anushiravani, Soroor Karimi, Hossein Varasteh Moradi, Abdol Rasoul Salmanmahini
Every stage of succession may provide certain species with habitat requirements which are impossible in other stages of succession. This study attempts to evaluate the different stages of succession in terms of composition and structure of bird populations in Hyrcanian forests. Bird-habitat relationships were investigated by comparing vegetation characteristics in three successional stages including late, initial stage, and urban areas. Bird richness, diversity, and abundance were measured within a 25-m radius of each of the 120 sampling points in various stages of succession and urban areas from May to April (2014) in the Ziarat catchment...
February 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28110442/correlates-of-health-related-quality-of-life-in-young-old-and-old-old-community-dwelling-older-adults
#17
Élvio R Quintal Gouveia, Bruna R Gouveia, Andreas Ihle, Matthias Kliegel, José A Maia, Sergi Bermudez I Badia, Duarte L Freitas
PURPOSE: This study aimed (1) to examine the role of potential correlates of HRQoL in a large representative sample of older adults, and (2) to investigate whether the relationships between HRQoL and potential factors differ as a function of HRQoL component (physical vs. mental) and/or age cohort (young-old vs. old-old). METHODS: This cross-sectional study included 802 older adults aged 60-79 years old. HRQoL was assessed using the SF-36 questionnaire. Functional fitness was assessed using the Senior Fitness Test...
January 21, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28110440/molecular-characterization-of-echinococcus-granulosus-isolates-from-bulgarian-human-cystic-echinococcosis-patients
#18
Irina Marinova, Markus Spiliotis, Junhua Wang, Marin Muhtarov, Ilias Chaligiannis, Smaro Sotiraki, Iskra Rainova, Bruno Gottstein, Ghalia Boubaker
Although cystic echinococcosis (CE) is highly endemic in Bulgaria, there is still scarce information about species and/or genotypes of the Echinococcus granulosus complex that infect humans. Our study tackled the genetic diversity of E. granulosus complex in a cohort of 30 Bulgarian CE patients. Ten animal E. granulosus isolates from neighboring Greece were additionally included. Specimens were comparatively analyzed for partial sequences of five mitochondrial (mt) (cox I, nad I, rrnS, rrnL, and atp6) and three nuclear (nc) genes (act II, hbx 2, and ef-1α) using a PCR-sequencing approach...
January 21, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28110433/a-comprehensive-analysis-of-cardiac-valve-plane-displacement-in-healthy-adults-age-stratified-normal-values-by-cardiac-magnetic-resonance
#19
Marco M Ochs, Thomas Fritz, Florian André, Johannes Riffel, Derliz Mereles, Matthias Müller-Hennessen, Evangelos Giannitsis, Hugo A Katus, Matthias G Friedrich, Sebastian J Buss
Cardiac valve plane displacement (CVPD) reflects longitudinal LV function. The purpose of the present study was to determine regional heterogeneity of CVPD in healthy adults to provide normal values by cardiac magnetic resonance (CMR). We measured the anterior aortic plane systolic excursion (AAPSE); the anterior, anterolateral, inferolateral, inferior, and inferoseptal mitral annular plane systolic excursion (MAPSE); and the lateral tricuspid annulus plane systolic excursion (TAPSE). Systolic excursion was measured as the distance from peak end-diastolic to peak end-sysstolic annular position (peak-to-peak) in cine images acquired in 2-, 3- and 4-chamber views...
January 21, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28110432/two-by-two-cross-over-study-to-evaluate-agreement-between-versions-of-a-quantitative-coronary-analysis-system-qangio-xa
#20
Kayoko Kozuma, Kosuke Kashiwabara, Tomohiro Shinozaki, Ken Kozuma, Koji Oba, Yutaka Matsuyama
The current version (ver. 7.3) of the popular quantitative coronary analysis system QAngio XA (Medis Medical Imaging System BV, Leiden, the Netherlands) is widely used without evaluating the agreement between the current and older versions in relation to a change of algorithms. The purpose of this study was to assess the equivalence of averages between QAngio XA versions 7.3 and 6.0. Based on the calculated sample size, angiographic images of 100 patients who underwent percutaneous coronary intervention of a single target lesion were randomly selected from two published studies (OUCH-TL: 154 lesions; OUCH-PRO: 160 lesions)...
January 21, 2017: International Journal of Cardiovascular Imaging
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