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https://www.readbyqxmd.com/read/29149147/hypothalamic-pituitary-adrenocortical-axis-suppression-following-a-single-epidural-injection-of-methylprednisolone-acetate
#1
Aleem Jameel Abdul, Babita Ghai, Dipika Bansal, Naresh Sachdeva, Anil Bhansali, Saravdeep Singh Dhatt
BACKGROUND: Epidural injections (EIs) are the most commonly performed minimally invasive intervention in managing chronic low back pain (CLBP). There is inconsistency in data to accurately predict the degree of hypothalamic-piuitary-adrenal (HPA) axis suppression in patients receiving exogenous steroid therapy, especially in the form of epidural steroid injections (ESIs). OBJECTIVE: We aim to quantify the degree and duration of HPA axis suppression after a single ESI of 80 mg methyl prednisolone acetate in patients with CLBP...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29149145/endoscopic-epidural-laser-decompression-versus-transforaminal-epiduroscopic-laser-annuloplasty-for-lumbar-disc-herniation-a-prospective-randomized-trial
#2
Chang Hong Park, Sang Ho Lee
BACKGROUND: Lumbar radicular pain often results from lumbar disc herniation, spinal stenosis, or degenerative spondylolisthesis. Minimally invasive disc decompression procedures, such as nucleo-annuloplasty or epiduroscopic neural decompression by laser, have been devised to treat such pain. OBJECTIVE: The short-term outcomes of disc decompression by endoscopic epidural laser decompression (EELD) or transforaminal epiduroscopic laser annuloplasty (TELA) were compared in patients with lumbar radicular pain due to disc herniation...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29146433/a-novel-technique-for-cervical-facet-joint-hyperplasia-spondylotic-radiculopathy-by-laminar-and-lateral-mass-screw-co-fixations
#3
Sun-Ren Sheng, Ke Wang, Majid Nisar, Jiao-Xiang Chen, Ai-Min Wu, Xiang-Yang Wang
OBJECTIVE: To describe the novel technique and report the outcomes of cervical spondylotic radiculopathy caused by facet joint hyperplasia treated with minimally invasive surgery by laminar and lateral mass screw co-fixations. METHOD: In this retrospective study, patients with spondylotic radiculopathy caused by facet joint hyperplasia underwent this technique in our unit between January 2010 and June 2015. Hospital charts, magnetic resonance imaging studies, and follow-up records for all the patients were reviewed...
November 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29138973/surgical-ligation-of-spinal-dural-arteriovenous-fistula
#4
Thomas Sorenson, Enrico Giordan, Delia Cannizzaro, Giuseppe Lanzino
BACKGROUND: Spinal dural arteriovenous fistulas (SDAVFs) are abnormal arteriovenous shunts between a radicular artery and the radicular vein, located in the dorsal surface of the dura sleeve, which drains in a retrograde manner into the coronal venous plexus of the spinal cord without an interposed capillary network. This result is a venous hypertension that reduces spinal cord perfusion and leads to ischemia and edema. Spontaneous resolution is extremely rare and, once symptomatic, the typical course is further progression with increased neurological impairment...
November 14, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29138074/outcome-of-transforaminal-epidural-steroid-injection-according-to-the-severity-of-cervical-foraminal-stenosis
#5
Min Son Kim, Dong Gyu Lee, Min Cheol Chang
BACKGROUND CONTEXT: Cervical transforaminal epidural steroid injection (TFESI) is considered one of the most effective treatments for radicular pain induced by cervical foraminal stenosis. PURPOSE: To evaluate the treatment outcome of TFESI according to the severity of cervical foraminal stenosis DESIGN: Retrospective study. PATIENT SAMPLE: Fifty-three patients with cervical radiculopathy due to cervical foraminal stenosis. OUTCOME MEASURES: Pain intensity was evaluated using a numeric rating scale (NRS) at pretreatment, 2 weeks, and 1, 2, and 3 months after TFESI...
November 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29133325/minimally-invasive-surgery-versus-open-surgery-in-the-treatment-of-lumbar-spondylolisthesis-study-protocol-of-a-multicentre-randomised-controlled-trial-misos-trial
#6
Mark P Arts, Jasper Fc Wolfs, Jos Ma Kuijlen, Godard Cw de Ruiter
INTRODUCTION: Patients with symptomatic spondylolisthesis are frequently treated with nerve root decompression, in addition to pedicle screw fixation and interbody fusion. Minimally invasive approaches are gaining attention in recent years, although there is no clear evidence supporting the proclamation of minimally invasive spine surgery (MISS) being better than open surgery. We present the design of the MISOS (Minimal Invasive Surgery versus Open Surgery) trial on the effectiveness of MISS versus open surgery in patients with degenerative or spondylolytic spondylolisthesis...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29130237/in-situ-forming-oxidised-hyaluronic-acid-adipic-acid-dihydrazide-hydrogel-for-prevention-of-epidural-fibrosis-after-laminectomy
#7
M H Hu, K C Yang, Y H Sun, Y C Chen, S H Yang, F H Lin
Post-operative epidural fibrosis is a biological response after laminectomy that may lead to clinical symptoms, such as radicular pain. An ideal material for prevention of epidural fibrosis should be able to inhibit fibroblast adhesions and reduce formation of scar tissue. An injectable hydrogel would be the material of choice for this purpose, since it could fill an irregular surgical defect completely, gelate in situ and be delivered in a minimally-invasive manner. The objective of this study was to evaluate, in vitro and in vivo, the cytocompatibility and anti-adhesive effect of an oxidised hyaluronic acid/adipic acid dihydrazide (oxi-HA/ADH) hydrogel...
November 13, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/29126222/lumbar-disc-herniation-the-association-between-quantitative-sensorial-test-and-magnetic-resonance-imaging-findings
#8
Serpil Canan Erbüyün, Gülgün Yilmaz Ovali, Beyhan Özyurt, E Alp Yentür
Objective: Quantitative sensorial tests (QST) are used for evaluating specific sensorial nerve function. In this study, QST and magnetic resonance imaging (MRI) findings are compared in lumbar disc herniation patients, and the accuracy of QST data was investigated. Material and Methods: Sixty-four patients between 18 and 70 years of age suffering from radicular pain with positive Lasegue's test were included in this study. Specific criteria included complaints due to L5 discopathy...
November 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29119110/a-randomized-controlled-trial-evaluating-the-effects-of-diosmin-in-the-treatment-of-radicular-pain
#9
Yinhe Wang, Xin Fang, Lei Ye, Yishan Li, Hongfei Shi, Yang Cao
Diosmin has been widely used to treat patients with vascular pain for its potent anti-inflammatory and analgesic effects. To evaluate the therapeutic effects of Diosmin in the treatment of radicular pain, we conducted an investigator-initiated, randomized, active-controlled noninferiority trial between January 1, 2009, and December 1, 2010. Diosmin (50 mg/kg/day) was orally administered to treat the radicular pain in 150 patients for one month. Another 150 patients with the same symptom were given 20% 250 ml mannitol (1 g/kg/day) for 7 days and dexamethasone (10 mg/day) for 3 days intravenously guttae...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29118526/panfolliculoma-a-clinical-case-report
#10
Roberto Estrada-Castañón, María Elisa Vega-Memije, Juan Carlos Cuevas-González, María de Guadalupe Chávez-López
Panfolliculoma is a benign neoplasm of follicular differentiation, and its morphological characteristics are similar to those of trichoblastoma, but it shows greater follicular differentiation. A 55-year-old female patient, visited for a dermatological consultation, presented comedo-like lesions on the eyelids, which were accompanied by moderate pruritus that spread gradually. On examination, the patient had localized dermatosis on the face, which symmetrically affected both upper eyelids and to a lesser extent the lower eyelids...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29114646/the-retromolar-canal-and-its-variations-classification-using-cone-beam-computed-tomography
#11
Penporn Luangchana, Suchaya Pornprasertsuk-Damrongsri, Jira Kitisubkanchana, Chanchai Wongchuensoontorn
OBJECTIVE: To determine the prevalence of the retromolar canal and its various patterns using cone beam computed tomography (CBCT). METHOD AND MATERIALS: CBCT images with the presence of mandibular third molars from August 2013 to May 2015 were retrospectively investigated. The presence of retromolar canal, its patterns, sides, as well as gender were evaluated by two observers. The pattern of retromolar canal was initially classified into three types: Type A, superior type; Type B, radicular-retromolar type; and Type C, dental type...
November 7, 2017: Quintessence International
https://www.readbyqxmd.com/read/29114274/outcomes-of-minimally-invasive-surgery-compared-to-open-posterior-lumbar-instrumentation-and-fusion
#12
Low Yong Lee, Zamzuri Idris, Tan Boon Beng, Teo Yian Young, Wong Chung Chek, Jafri Malin Abdullah, Wong Sii Hieng
Introduction: Degenerative spine disease is increasingly common. There are many spinal fusion techniques used to treat degenerative spine disease. This study aims to compare the functional outcome of open versus minimally invasive surgery (MIS) technique in posterior lumbar instrumentation and fusion in degenerative spine disease and to evaluate the perioperative outcome and complications between MIS and open surgery. Materials and Methods: This is an observational cross-sectional study conducted on all degenerative spine disease patients who underwent both methods of posterior lumbar instrumentation and fusion from 2010 to 2014 by the Orthopedic and Neurosurgery Department, Sarawak General Hospital...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29110218/cervical-sagittal-balance-a-biomechanical-perspective-can-help-clinical-practice
#13
REVIEW
Avinash G Patwardhan, Saeed Khayatzadeh, Robert M Havey, Leonard I Voronov, Zachary A Smith, Olivia Kalmanson, Alexander J Ghanayem, William Sears
PURPOSE: In this article, we summarize our work on understanding the influence of cervical sagittal malalignment on the mechanics of the cervical spine. METHODS: Biomechanical studies were performed using an ex vivo laboratory model to study the kinematic and kinetic response of human cervical spine specimens in the setting of cervical sagittal imbalance. The model allowed controlled variations of C2-C7 Sagittal Vertical Alignment (C2-C7 SVA) and T1-Slope so that clinically relevant sagittally malaligned profiles could be prescribed, while maintaining horizontal gaze, and their biomechanical consequences studied...
November 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29107720/sporadic-intradural-extramedullary-hemangioblastoma-of-the-cauda-equina-case-report-and-literature-review
#14
Douglas Blaty, Michael Malos, Thomas Palmrose, Stephen McGirr
BACKGROUND: The purpose of this case report is to present a rare finding of an intradural extramedullary hemangioblastoma of the cauda equina, with literature review. Spinal hemangioblastomas account for 1-5% of all spinal cord tumors. While spinal hemangioblastomas are rare, it is exceedingly rare to have a case of intradural extramedullary hemangioblastoma of the spine, especially in isolation without von-Hippel-Lindau syndrome. Only 20 previous cases have been reported. CASE DESCRIPTION: An 82-year-old male presented with MRI evidence of an intradural mass at the L4 spinal level...
October 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29105592/biologic-annulus-fibrosus-repair-a-review-of-preclinical-in-vivo-investigations
#15
Stephen Rogers Sloan, Marianne Lintz, Ibrahim Hussain, Roger Härtl, Lawrence J Bonassar
Lower back pain, the leading cause of workplace absences and disability, is often attributed to intervertebral disc (IVD) degeneration in which nucleus pulposus (NP) herniates through lesions in the annulus fibrosus (AF) and impinges on the spinal cord and surrounding nerves. Surgeons remove extruded NP via discectomy when indicated by local/radicular pain supported by radiographic evidence, however current interventions do not alter the underlying disease or seal the AF. The reported rates of recurrent herniation or pain following discectomy cases range from 5-25%, which has pushed spine research in recent years towards annular repair and closure strategies...
November 4, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29104840/spinal-shortening-for-recurrent-tethered-cord-syndrome-via-a-lateral-retropleural-approach-a-novel-operative-technique
#16
Jeffrey A Steinberg, Arvin R Wali, Joel Martin, David R Santiago-Dieppa, David Gonda, William Taylor
Spine shortening via vertebral osteotomy (SSVO) for recurrent tethered cord syndrome (TCS) is a novel surgical technique that avoids the complication profile associated with revision detethering. While SSVO has previously been described via a posterior approach, we describe a lateral retropleural approach for SSVO in recurrent TCS in a 21-year-old female. Our patient presented with progressive lower extremity weakness, bowel and bladder incontinence, and back pain in the setting of childhood repair of myelomeningocele and two previous detethering procedures...
August 31, 2017: Curēus
https://www.readbyqxmd.com/read/29102345/a-case-report-paediatric-surfer-s-myelopathy
#17
Rebecca Scatchard, Joao Alves Rosa, Philippa Bowen, Alex Mortimer, Peta M Sharples, Andrew L Lux
Surfer's myelopathy was first described by Thompson et al., in 2004.(1) It is a rare cause of sudden spinal cord injury that occurs in the absence of direct trauma to the spinal area in novice healthy surfers. We present the case of the youngest patient we are aware of to be diagnosed with surfer's myelopathy following actual surfing. A clear aetiology for surfer's myelopathy has not previous been described. However, the hypothesis that there is ischaemia to the lower spinal cord is supported by our case, where we present the first clear angiographic evidence of the occlusion of the great anterior radicular artery of Adamkiewicz in a patient diagnosed with surfer's myelopathy...
October 7, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29097290/in-vitro-evaluation-of-methylene-blue-removal-from-root-canal-after-photodynamic-therapy
#18
Karen Müller Ramalho, Sandra Ribeiro Cunha, Eric Mayer-Santos, Carlos de Paula Eduardo, Patricia Moreira de Freitas, Ana Cecilia Correa Aranha, Cacio Moura-Netto
In Endodontics, photosensitizers' such as methylene blue and toluidine blue have been used in photodynamic therapy due to their positive results. However, they can stain the dentin from the root canal after Photodynamic Therapy (PDT). The present in vitro study aimed to evaluate different stain removal protocols from root canal after PDT using methylene blue (MB) dye. After mechanical preparation of the root canal of 40 uni-radicular human teeth, PDT was performed using 0,01% MB with parameters of 3minutes of pre-irradiation and a diode laser irradiation emitting at 660nm, 40mW, 4minutes, 9...
October 30, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29093979/respiratory-epithelium-lined-cyst-of-the-maxilla-differential-diagnosis
#19
C P Martinelli-Kläy, S Chatelain, F Salvado, T Lombardi
Maxillary cysts, including the cysts lined by respiratory epithelium, can present a diagnostic challenge. We report an unusual case of a maxillary cyst on an endodontically treated tooth #16, in which the cavity was totally lined by a respiratory epithelium. The patient, a 35-year-old male, presented with a generalized chronic periodontitis and complained of a pain in the tooth #16 region. A periodontal pocket extending to the root apices with pus coming out from the gingival was found. A combined endodontic periodontal was observed on a panoramic radiography...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/29076468/-percutaneous-endoscopic-discectomy-in-the-treatment-of-patients-with-degenerative-diseases-of-the-lumbosacral-spine
#20
N A Konovalov, D S Asyutin, V A Korolishin, I U Cherkiev, B A Zakirov
Modern surgery uses a variety of treatments for spine pathology. Endoscopic techniques have become particularly popular across the world over the past decade. In this article, we summarize our experience and analyze the immediate and long-term results of surgical treatment of lumbar disc herniation using a percutaneous fully endoscopic technique for removing the herniated intervertebral disc, which is new for Russian medical practice. OBJECTIVE: to evaluate the efficacy of percutaneous endoscopic discectomy in the treatment of herniated lumbar discs in patients with radicular pain syndrome...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
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