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https://www.readbyqxmd.com/read/29202898/isolated-psychosis-during-exposure-to-very-high-and-extreme-altitude-characterisation-of-a-new-medical-entity
#1
Katharina Hüfner, Hermann Brugger, Eva Kuster, Franziska Dünsser, Agnieszka E Stawinoga, Rachel Turner, Iztok Tomazin, Barbara Sperner-Unterweger
BACKGROUND: Psychotic episodes during exposure to very high or extreme altitude have been frequently reported in mountain literature, but not systematically analysed and acknowledged as a distinct clinical entity. METHODS: Episodes reported above 3500 m altitude with possible psychosis were collected from the lay literature and provide the basis for this observational study. Dimensional criteria of the Diagnostic and Statistical Manual of Mental Disorders were used for psychosis, and the Lake Louise Scoring criteria for acute mountain sickness and high-altitude cerebral oedema (HACE)...
December 5, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29184234/the-effect-of-gamma-irradiation-on-the-properties-of-cucumber
#2
Reza Khalili, Navid Ayoobian, Mehrdad Jafarpour, Babak Shirani
In this study, the effect of gamma irradiation on the shelf life and properties of cucumber was investigated. These properties include weight reduction, fruit density, juice, tissue firmness, total soluble solids (TSS), total titratable acidity, chlorophyll and vitamin C, pH, marketability, flavor, frostbite and fungal effects. For this purpose, cucumbers were irradiated with dose of 2, 2.5 and 3 kGy. The exposure time was calculated by MCNP4C; the Monte Carlo particle transport code. Three types of fungi (white-Sclerotinia sclerotiorum, gray-Botrytis cinerea and olive-Cladosporium cucumerinum), were used to infect some samples...
December 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29164310/relevance-of-trpa1-and-trpm8-channels-as-vascular-sensors-of-cold-in-the-cutaneous-microvasculature
#3
REVIEW
Y Pan, D Thapa, L Baldissera, F Argunhan, A A Aubdool, S D Brain
Cold exposure is directly related to skin conditions, such as frostbite. This is due to the cold exposure inducing a vasoconstriction to reduce cutaneous blood flow and protect against heat loss. However, a long-term constriction will cause ischaemia and potentially irreversible damage. We have developed techniques to elucidate the mechanisms of the vascular cold response. We focused on two ligand-gated transient receptor potential (TRP) channels, namely, the established "cold sensors" TRP ankyrin 1 (TRPA1) and TRP melastin (TRPM8)...
November 21, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/29142364/bone-scan-in-evaluation-of-bone-viability-in-severe-frostbite-of-the-hand
#4
Ishan Garg, Maria J Baladron Zanetti, Ayse T Kendi
A 39-year-old male presented to the emergency department (ED) with frostbite to the fingers of both hands. In the ED, he received warm baths, acetylsalicylic acid, clopidogrel, and heparin. A three-phase bone scintigraphy with technetium-99m-methylene diphosphonate revealed absent radiotracer uptake in distal phalanges of both hands. The patient received acetylsalicylic acid, clopidogrel and wound care for the next 5 days and made an excellent recovery with satisfactory wound healing in both hands. Early rapid rewarming and reperfusion can improve the prognosis significantly and therefore bone scan done within first 1-2 days may give spurious results...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29077423/update-cold-weather-injuries-active-and-reserve-components-u-s-armed-forces-july-2012-june-2017
#5
Francis L O'Donnell, Shauna Stahlman, Alexis A Oetting
From July 2016 through June 2017, a total of 387 members of the active (n=328) and reserve (n=59) components had at least one medical encounter with a primary diagnosis of cold injury. Among active component service members, the total number of cold injuries in the 2016-2017 cold season was the lowest since 1999 and the overall incidence rate was lower than in any of the previous four cold seasons. Frostbite was the most common type of cold injury. During the five cold seasons in the surveillance period (2012-2017), rates tended to be higher among service members who were in the youngest age groups, female, non-Hispanic black, or in the Army...
October 2017: MSMR
https://www.readbyqxmd.com/read/29061876/bet-1-does-the-use-of-emollients-prevent-frostbite-to-the-face
#6
Emmy De Buck
A short cut review was carried out to establish whether routine use of emollients on the face reduced the incidence of frostbite in cold environments. 126 papers were found using the reported searches, of which three presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that the use of emollients on the face is not a good protection against frostbite and may even result in a higher risk...
November 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29037403/analytical-expressions-for-estimating-endurance-time-and-glove-thermal-resistance-related-to-human-finger-in-cold-conditions
#7
Amir Fallahi, Mohammad Reza Salimpour, Ebrahim Shirani
Frostbite is considered the severest form of cold injury and can lead to necrosis and loss of peripheral appendages. Therefore, prediction of endurance time of limb's tissue in cold condition is not only necessary but also crucial to estimate cold injury intensity and to choose appropriate clothing. According to the previous work which applied a 3-D thermal model for human finger to analyze cold stress, in this study, an expression is presented for endurance time in cold conditions to prevent cold injury. A formula is also recommended to select a proper glove with specific thermal resistance based on the ambient situation and cold exposure time...
October 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28963381/bet-2-treatment-of-frostbite-with-iloprost
#8
Margo Kaller
A short cut review was carried out to establish whether an infusion of iloprost can be used to treat frostbite to reduce the risk of needing an amputation. Three studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that iloprost may reduce the risk of amputation after frostbite.
October 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28885934/medical-encounters-during-a-joint-canadian-u-s-exercise-in-the-high-arctic-exercise-arctic-ram
#9
Wendy Sullivan-Kwantes, Paul Dhillon, Len Goodman, Joseph J Knapik
The Arctic Ram Exercise was conducted in February 2016, near Resolute Bay on Cornwallis Island in Nunavut, Canada, to demonstrate the ability of the Canadian Armed Forces (CAF) to rapidly deploy to the arctic as an immediate response team. This report describes medical problems experienced by the 187 CAF and 28 U.S. forces involved in the exercise. Sixty-six airborne soldiers performed tactical static line jumps and linked up with soldiers on the ground for the exercise. Medical events were recorded by medics on the drop zone and by medical personnel at the Unit Medical Station in Resolute Bay...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28877129/iatrogenic-full-thickness-frostbite-injury-caused-by-the-use-of-a-conductive-cooling-device
#10
Corbin Muetterties, Eric Weiss, Sandra Tomlinson-Hansen, William Hughes
Reports of iatrogenic cold thermal injuries are rare in the literature. Conductive cooling devices, typically employed for their neuroprotective effects, use conductive hydrogel pads to achieve rapid and precise temperature control approaching the level of water immersion. Despite a number of built-in safeguards, prolonged or improper use of these devices can lead to significant thermal injury. To the best of their knowledge, the authors describe the first report of a significant iatrogenic full-thickness injury caused by the use of a surface cooling system in a patient who had recently suffered a cerebrovascular accident...
August 31, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28783893/delayed-treatment-of-frostbite-with-hyperbaric-oxygen-a-report-of-two-cases
#11
Corine A Lansdorp, Gert R Roukema, Onno Boonstra, Jan Dokter
Frostbite is an injury caused by the freezing of tissue, causing varied levels of tissue damage and necrosis. Case reports have shown a positive effect of hyperbaric oxygen (HBO₂) in such injuries, in acute cases as well as delayed (up to 21 days) presentation with complications. In this case report we present the course of hyperbaric treatment of two patients (a brother and sister, age 58 and 62) who sustained frostbite injuries to both feet 28 days earlier while hiking in the Himalayas. They were initially treated in Nepal following local protocol; afterward their primary care in the Netherlands was managed by the Burn Centre at Maasstad Hospital in Rotterdam...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28702681/intra-arterial-thrombolysis-for-extremity-frostbite-decreases-digital-amputation-rates-and-hospital-length-of-stay
#12
Nishant Patel, Dhivya R Srinivasa, Ravi N Srinivasa, Joseph J Gemmete, Venkat Krishnamurthy, Narasimham Dasika, Shilpa N Reddy, Matthew L Osher, Erika D Sears, Jeffrey Forris Beecham Chick
PURPOSE: To report outcomes of intra-arterial thrombolysis versus non-thrombolytic management of severe frostbite with respect to digital amputation rates and hospital length of stay (LOS). MATERIALS AND METHODS: Seventeen patients with severe frostbite were identified from 2000 to 2017. Eight (47%) patients with mean age of 40 years underwent intra-arterial thrombolysis and served as the treatment group. Nine (53%) patients with mean age of 53 years received non-thrombolytic management and served as the control group...
July 12, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28680204/role-of-99m-tc-mdp-bone-scan-in-delineation-of-ischaemic-zone-in-cases-of-severe-frostbite
#13
Arun Ravi John, Anurag Jain, Braj Kishore, Aniruddha G Pandit
Frostbite or cold burn is the medical condition in which localized damage is caused to exposed skin and subcutaneous tissue due to freezing. Frostbite most likely involves body parts farthest from the heart and those with large exposed areas. At or below 0 °C (32 °F), blood vessels close to the skin start to constrict, and blood is shunted away from the extremities via the physiological feedback action of glomus bodies. This peripheral vasoconstriction helps to conserve core body temperature. In extreme cold, or when certain parts of the body are exposed to cold conditions for long periods, this protective mechanism can reduce blood flow in some areas of the body to dangerously low levels...
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28652661/observation-of-the-effect-of-targeted-therapy-of-64-slice-spiral-ct-combined-with-cryoablation-for-liver-cancer
#14
Qiao-Huan Yan, Dian-Guo Xu, Yan-Feng Shen, Ding-Ling Yuan, Jun-Hui Bao, Hai-Bin Li, Ying-Gang Lv
AIM: To observe the effect of targeted therapy with 64-slice spiral computed tomography (CT) combined with cryoablation for liver cancer. METHODS: A total of 124 patients (142 tumors) were enrolled into this study. According to the use of dual-slice spiral CT or 64-slice spiral CT as a guide technology, patients were divided into two groups: dual-slice group (n = 56, 65 tumors) and 64-slice group (n = 8, 77 tumors). All patients were accepted and received targeted therapy by an argon-helium superconducting surgery system...
June 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28630224/successful-conservative-treatment-of-severe-frostbite-lesions-in-a-greenlandic-inuit
#15
Martin Ekdahl, Luit Penninga
Frostbite may cause lesions. The severity ranges from superficial wounds to severe cases with loss of limbs and tissue. Hence, proper treatment is of utmost importance. We present a case of an 18-year-old man from Arctic Greenland who was admitted with severe frostbite lesions involving both hands. The patient had fallen asleep outside during extreme temperatures. He was treated conservatively with proper wound care, antibiotics and intensive physical therapy. The patient made a full recovery without sequelae...
June 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28570307/early-mobilization-in-lower-extremity-frostbite-injury-preliminary-experience-at-a-single-burn-center
#16
Michelle Dole, Frederick W Endorf, Jon Gayken, Ryan Fey, Rachel M Nygaard
Cold exposure that leads to frostbite puts patients at high risk for extremity amputations. Recent treatment advances, such as thrombolytic administration, have decreased amputation rates. However, little is known about patient outcomes with early mobilization of affected limbs. A retrospective review of 41 patients admitted for lower extremity frostbite was performed at an urban hospital burn unit. All patients received the institution's standard frostbite treatment protocol. The study group was allowed to bear weight within 72 hours, while the control group was immobilized beyond this time frame...
May 26, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28516256/-skin-diseases-associated-with-environmental-factors
#17
REVIEW
Vera Mahler
BACKGROUND: Multiple environmental exposures may derange the regulatory and repair mechanisms of the skin and lead to dermatological disease. OBJECTIVES: Provide an overview of non-allergic skin diseases associated with environmental factors. MATERIALS AND METHODS: Review of current scientific evidence for associations of non-allergic skin diseases with environmental exposures: irritation, chemicals, infection, UV-radiation, temperature. RESULTS: Predisposition (constitution e...
June 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28507785/a-retrospective-chart-review-of-chronic-wound-patients-treated-with-topical-oxygen-therapy
#18
Karen Copeland, Angie R Purvis
Objective: Topical oxygen devices are Food and Drug Administration (FDA) cleared for the following indications for use of various etiologies: skin ulcerations due to diabetes, venous stasis, postsurgical infections and gangrenous lesions, decubitus ulcers; amputations/infected stumps; skin grafts; burns; and frostbite. The goal of this study was to understand the impact of topical oxygen therapy (TOT) on patient outcomes, including amputation and healing rates. Approach: This retrospective chart review included records collected between January 1, 2007, and July 18, 2016, from male and female patients ranging in age from 4 years to 105 years...
May 1, 2017: Advances in Wound Care
https://www.readbyqxmd.com/read/28497276/thermal-perception-thresholds-among-workers-in-a-cold-climate
#19
Lage Burström, Bodil Björ, Tohr Nilsson, Hans Pettersson, Ingemar Rödin, Jens Wahlström
PURPOSE: To investigate whether exposure to cold could influence the thermal perception thresholds in a working population. METHODS: This cross-sectional study was comprised of 251 males and females and was carried out at two mines in the northern part of Norway and Sweden. The testing included a baseline questionnaire, a clinical examination and measurements of thermal perception thresholds, on both hands, the index (Digit 2) and little (Digit 5) fingers, for heat and cold...
May 11, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28483389/battlefield-trauma-induced-hypothermia-transitioning-the-preferred-method-of-casualty-rewarming
#20
REVIEW
Brad L Bennett, John B Holcomb
For centuries, cold and wet weather has affected military combat operations leading to tremendous loss of manpower caused by cold-weather-related injuries including trench foot, frostbite, and hypothermia. The initial battlefield management of hypothermia in military personnel had not advanced significantly following many wars and conflicts until 2006. The aim of this review is to: 1) provide an overview of trauma-induced hypothermia (TIH); 2) highlight the Department of Defense strategy for the implementation of a hypothermia clinical management program for battlefield (prehospital) casualties; 3) highlight the research and development of the Hypothermia Prevention and Management Kit (HPMK) as the preferred field rewarming system for battlefield TIH; and 4) emphasize how the HPMK can be easily transitioned to the civilian sector for active rewarming of both accidental and TIH patients...
June 2017: Wilderness & Environmental Medicine
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