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https://www.readbyqxmd.com/read/27891244/the-effectiveness-of-regional-cooling-for-paclitaxel-induced-peripheral-neuropathy
#1
Junya Sato, Megumi Mori, Satoru Nihei, Masumi Kumagai, Satoshi Takeuchi, Masahiro Kashiwaba, Kenzo Kudo
BACKGROUND: There are currently no promising therapies available to treat or prevent peripheral neuropathy (PN) induced by anticancer drugs in a cumulative dose-dependent manner. In this study, we investigated the efficacy of regional cooling of hands and feet in preventing paclitaxel (PTX)-induced PN. METHODS: Patients with gynecologic cancer who received a tri-weekly cycle of chemotherapy including PTX at doses of 150-175 mg/m(2) were included in this study. Regional cooling was performed by covering patient hands and feet with cold insulators during PTX administration (regional cooling group)...
2016: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/27851241/1606-from-frostbite-to-complex-valve-replacement
#2
Shubash Adhikari, Afoma King, Matthew Harinstein
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27816378/dull-brains-and-frozen-feet-a-historical-essay-on-cold
#3
Harvey V Lankford
This essay will review historical and medical aspects of cold exposure, hypothermia, and frostbite during the Napoleonic era. The 19th century writings of Dominique Jean Larrey, Pierre Jean Moricheau-Beaupré, and others are used to provide an evocative supporting narrative to illustrate some of the cold illnesses, physiology, and theory of both an earlier era and the present time. Medical care for over a century followed the how but not the why of treating frostbite and hypothermia slowly with snow or cold water rather than heat...
November 2, 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27792353/update-cold-weather-injuries-active-and-reserve-components-u-s-armed-forces-july-2011-june-2016
#4
Francis L O'Donnell, Stephen B Taubman
From July 2015 through June 2016, a total of 447 members of the active (n=383) and reserve (n=64) components had at least one medical encounter with a primary diagnosis of cold injury. The numbers of affected individuals in both components were the lowest since the 2011-2012 cold season, when the total was 394. In the active component, the service-specific incidence rates for each of the four services were lower than the respective rates for the previous (2014-2015) cold season. Frostbite was the most common type of cold injury...
October 2016: MSMR
https://www.readbyqxmd.com/read/27685089/effects-of-low-frequency-pulsed-electromagnetic-fields-on-plateau-frostbite-healing-in-rats
#5
Mingke Jiao, Lin Lou, Lin Jiao, Jie Hu, Peng Zhang, Zhongming Wang, Wenjuan Xu, Xiliang Geng, Hongping Song
Plateau frostbite (PF) treatments have remained a clinical challenge because this condition injures tissues in deep layers and affected tissues exhibit unique pathological characteristics. For instance, low-frequency pulsed electromagnetic field (PEMF) can affect tissue restoration and penetrate tissues. Therefore, the effect of PEMF on PF healing should be investigated. This study aimed to evaluate the effects of low-frequency PEMF on PF healing systematically. Ninety-six Sprague-Dawley rats were randomly and equally divided into three groups: normal control, partial thickness plateau frostbite (PTPF), and PTPF with low-frequency PEMF exposure (PTPF + PEMF)...
September 29, 2016: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/27617909/initial-experience-alleviation-of-pain-with-percutaneous-ct-guided-cryoablation-for-recurrent-retroperitoneal-soft-tissue-sarcoma
#6
Wen-Zhe Fan, Li-Zhi Niu, Yu Wang, Xue-Hua Yao, Ying-Qiang Zhang, Guo-Sheng Tan, Jian-Yong Yang, Jia-Ping Li
PURPOSE: To evaluate the pain-alleviating effect of computed tomography (CT)-guided percutaneous cryoablation for recurrent retroperitoneal soft-tissue sarcomas (RPSs). MATERIALS AND METHODS: Data from 19 men and 20 women (median age, 50.3 y) with recurrent malignant RPS who underwent percutaneous cryoablation were reviewed retrospectively. A total of 50 tumors were treated by cryoablation, including a single tumor in 29 patients, 2 tumors in 9, and 3 tumors in 1...
December 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27613331/application-of-a-novel-rectal-cooling-device-in-hypothermia-therapy-after-cerebral-hypoxia-ischemia-in-rats
#7
Peng Liu, Rui Yang, Zelan Zuo
BACKGROUND: A new rectal cooling device for therapeutic hypothermia (TH) therapy is designed and is applied in TH treatment of SD rats with ischemic-hypoxic brain damage. METHODS: Healthy adult SD rats (n = 45) were randomly assigned into four groups: the healthy control group (n = 5), the ischemia and hypoxia group (n = 10), the rectal TH cooling group (n = 18), and the ice blanket TH cooling group (n = 11). The rats in the rectal cooling and ice blanket TH groups received 12 h treatment after hypoxic-ischemic brain damage had been established, while those in the ischemia and hypoxia group did not...
2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27606554/time-matters-in-severe-frostbite-assessment-of-limb-digit-salvage-on-the-individual-patient-level
#8
Rachel M Nygaard, Alexandra M Lacey, Ashley Lemere, Michelle Dole, Jon R Gayken, Anne L Lambert Wagner, Ryan M Fey
Severe frostbite is associated with high levels of morbidity through loss of digits or limbs. The aim of this study was to examine the salvage rate following severe frostbite injury. Frostbite patients from 2006 to 2014 were identified in the prospectively maintained database at a single urban burn and trauma center. Patients with imaging demonstrating a lack of blood flow in limbs/digits were included in the analysis (N = 73). The Hennepin Frostbite Score was used to quantify frostbite injury and salvage. This score provides a single value to assess each individual patient's salvage rate...
August 18, 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27567997/percutaneous-ct-guided-cryoablation-of-the-salivary-glands-in-a-porcine-model
#9
Ji Y Buethe, Salim Abboud, Kristie Brock, Greg Nizialek, Rod Rezaee, Jay Wasman, Jonathan Frankel, Dean A Nakamoto
PURPOSE: To evaluate the imaging, histologic changes and safety of computed tomography (CT)-guided cryoablation of the parotid glands in a porcine model. MATERIALS AND METHODS: Unilateral CT-guided parotid gland cryoablation was performed in 5 juvenile miniature pigs. The ablated parotid glands underwent 2 cycles of 10-minute freeze and 5-minute thaw using three 17-g cryoprobes. The animals were monitored daily for complications including pain, frostbite, infection, and sialocele or fistula formation...
December 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27514559/-early-reduction-of-frostbite-for-depth-of-management-of-occupational-acute-finger
#10
H Tang, Y Shi, N Z Qu
No abstract text is available yet for this article.
June 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/27494386/frostbite-spectrum-of-imaging-findings-and-guidelines-for-management
#11
John D Millet, Richard K J Brown, Benjamin Levi, Casey T Kraft, Jon A Jacobson, Milton D Gross, Ka Kit Wong
Frostbite is a localized cold thermal injury that results from tissue freezing. Frostbite injuries can have a substantial effect on long-term limb function and mobility if not promptly evaluated and treated. Imaging plays a critical role in initial evaluation of frostbite injuries and in monitoring response to treatment. A multimodality approach involving radiography, digital subtraction angiography (DSA), and/or multiphase bone scintigraphy with hybrid single photon emission computed tomography (SPECT)/computed tomography (CT) is often necessary for optimal guidance of frostbite care...
November 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27413384/synergistic-effect-of-ferulic-acid-and-z-ligustilide-major-components-of-a-sinensis-on-regulating-cold-sensing-protein-trpm8-and-tpra1-in-vitro
#12
Yuwei Pan, Guoping Zhao, Zejian Cai, Fengguo Chen, Dandan Xu, Si Huang, Hai Lan, Yi Tong
Angelica sinensis has been used to attenuate cold-induced cutaneous vasospasm syndrome, such as Raynaud's disease and frostbite, in China for many years. Ferulic acid (PubChem CID: 445858) and Z-ligustilide (PubChem CID: 529865), two major components extracted from Angelica sinensis, had been reported to inhibit vasoconstriction induced by vasoconstrictors. In this study, the pharmacological interaction in regulating cold-induced vascular smooth muscle cell contraction via cold-sensing protein TRPM8 and TRPA1 was analyzed between ferulic acid and Z-ligustilide...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27396924/pathophysiologic-determination-of-frostbite-under-high-altitude-environment-simulation-in-sprague-dawley-rats
#13
Jie Hu, Hua Li, Xiliang Geng, Lin Jiao, Hongping Song, Lin Lou, Mingke Jiao
OBJECTIVES: Pathophysiologic changes of frostbite have been postulated but rarely understood, especially the changes caused by chilly high altitude environment. Therefore, we investigated the pathophysiologic changes of high altitude frostbite (HAF) caused by cold and hypoxia. METHODS: Forty Sprague-Dawley rats were randomly divided into 5 equal groups, namely, control, superficial HAF (S-HAF), partial-thickness HAF (PT-HAF), full-thickness HAF (FT-HAF), and partial-thickness normal frostbite (PT-NF) groups...
September 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27363299/catheter-directed-intraarterial-thrombolysis-as-part-of-a-multidisciplinary-management-protocol-of-frostbite-injury
#14
Sidhartha Tavri, Suvranu Ganguli, Roy G Bryan, Jeremy Goverman, Raymond Liu, Zubin Irani, T Gregory Walker
PURPOSE: To evaluate intraarterial catheter-directed thrombolysis for prediction and prevention of delayed surgical amputation as part of multidisciplinary management of frostbite injury. MATERIALS AND METHODS: A retrospective review was performed of 13 patients (11 men, 2 women; median age, 33.4 y; range, 8-62 y) at risk of tissue loss secondary to frostbite injury and treated with catheter-directed tissue plasminogen activator (t-PA) thrombolysis. Amputation data were assessed on follow-up (mean, 23 mo; range, 9-83 mo)...
August 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27306723/spect-ct-in-the-evaluation-of-frostbite
#15
Casey Kraft, John D Millet, Shailesh Agarwal, Stewart C Wang, Kevin C Chung, Richard K J Brown, Benjamin Levi
Frostbite remains a challenging clinical scenario with multiple treatment algorithms and variable results. Currently, frostbite management often follows a conservative approach with rewarming followed by wound care and delayed amputation. We review seven patients where single-photon emission computed tomography (SPECT) fused with conventional computed tomography was used to evaluate tissue viability for earlier directed debridement and limb salvage. The goal of this report is to evaluate SPECT/CT as an appropriate modality for the screening of necrotic bone for earlier amputation in patients with frostbite...
June 10, 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27223071/percutaneous-computed-tomography-guided-cryoablation-for-recurrent-retroperitoneal-soft-tissue-sarcoma-a-study-of-safety-and-efficacy
#16
Wenzhe Fan, Lizhi Niu, Yu Wang, Yingqiang Zhang, Xuehua Yao, Guosheng Tan, Jianyong Yang, Jiaping Li
AIMS: To evaluate the use of computed tomography image-guided percutaneous cryoablation for recurrent retroperitoneal soft tissue sarcomas (RPSs). RESULTS: Adverse events were limited to grades 1 and 2, included fever (n = 19), local pain (n = 11), emesis (n = 10), frostbite (n = 6), and nerve injury (n = 1). Fever was more frequent in the large tumor group (15.8%) than in small tumor group (1.9%) (P = 0.008). Median PFS and OS were 37.0 ± 7.7 months (range, 4-39 months) and 43...
July 5, 2016: Oncotarget
https://www.readbyqxmd.com/read/27146710/cold-thermal-injury-from-cold-caps-used-for-the-prevention-of-chemotherapy-induced-alopecia
#17
Viswanath Reddy Belum, Giselle de Barros Silva, Mariana Tosello Laloni, Kathryn Ciccolini, Shari B Goldfarb, Larry Norton, Nancy T Sklarin, Mario E Lacouture
INTRODUCTION: The use of scalp cooling for the prevention of chemotherapy-induced alopecia (CIA) is increasing. Cold caps are placed onto the hair-bearing areas of the scalp for varying time periods before, during, and after cytotoxic chemotherapy. Although not yet reported, improper application procedures could result in adverse events (AEs). At present, there are no evidence-based scalp cooling protocols, and there is no regulatory oversight of their use. OBJECTIVE: To report the occurrence of cold thermal injury (frostbite) on the scalp, following the use of cold caps for the prevention of CIA...
June 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27143949/angioplasty-of-forearm-arteries-as-a-finger-salvage-procedure-for-patient-with-end-stage-renal-failure
#18
Yuk Law, Yiu Che Chan, Stephen Wing-Keung Cheng
Due to the relatively low metabolic demand and extensive collaterals of the upper limb, peripheral arterial disease seldom leads to tissue loss, except in patients with end-stage renal failure (ESRF), rheumatologic diseases, Raynaud's disease, frostbites, or distal emboli. We report a case of a 51-year-old lady with ESRF who presented to our tertiary referral vascular center with infected gangrene of her right ring finger. Duplex ultrasound showed that her forearm arteries were severely diseased. Digital subtraction angiogram showed severe multilevel stenoses/occlusions in her forearm radial and ulnar arteries...
2016: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/27099089/north-pole-marathon-laboratory-lessons-and-field-success
#19
Martin J Barwood, Holly Burrows, Jessica Cessford
BACKGROUND: This case study documents the training, laboratory preparation, and in-race performance data from Great Britain's top finisher in the 13(th) edition of the UVU North Pole Marathon. CASE REPORT: We report data from a preparatory laboratory test in simulated cold conditions (-15°C) with and without wind chill during high- and low-intensity expected 'race pace' running. These tests examined the adequacy of the selected clothing assembly and provided recommendations for the race...
May 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27091617/-lumbar-sympathectomy-literature-review-over-the-past-15-years
#20
M Pekař, M Mazur, A Pekařová, J Kozák, A Foltys
INTRODUCTION: Lumbar sympathectomy (LS) irreversibly damages a part of the sympathetic trunk and adjacent ganglia between L1 and L5, typically between L2 and L4. The first LS was performed in 1923. Initially, it used to be performed very often; however, with the progress of vascular and endovascular surgery its importance gradually continues to decline. The aim of the paper is to present literature review focusing on LS over the past 15 years. METHOD: Literature review of 113 academic articles found in academic journal databases...
March 2016: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
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