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https://www.readbyqxmd.com/read/28496551/lack-of-association-between-toxoplasma-gondii-infection-and-diabetes-mellitus-a-matched-case-control-study-in-a-mexican-population
#1
Cosme Alvarado-Esquivel, Nayely Loera-Moncivais, Jesus Hernandez-Tinoco, Luis Francisco Sanchez-Anguiano, Guillermina Hernandez-Madrid, Elizabeth Rabago-Sanchez, Maria Magdalena Centeno-Tinoco, Ada A Sandoval-Carrillo, Jose M Salas-Pacheco, Oscar Vladimir Campos-Moreno, Elizabeth Irasema Antuna-Salcido
BACKGROUND: Very little is known about the association between infection with Toxoplasma gondii (T. gondii) and diabetes mellitus. We perform an age- and gender-matched case-control study to determine the association of T. gondii infection and diabetes mellitus. METHODS: Cases included 156 patients with diabetes mellitus and 156 controls without diabetes mellitus who attended in two public clinics in Durango City, Mexico. Sera of cases and controls were tested for the presence of anti-Toxoplasma IgG and IgM antibodies using commercially available enzyme-linked fluorescence assays (ELFA)...
June 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28464065/genome-wide-association-analysis-for-drought-tolerance-and-associated-traits-in-common-bean
#2
Valerio Hoyos-Villegas, Qijian Song, James D Kelly
A genome-wide association study explored the genetic basis of variation for drought tolerance and related traits in a Middle American diversity panel comprising 96 common bean ( L.) genotypes. The panel was grown under irrigated and rainfed conditions and single nucleotide polymorphism (SNP) data were used to explore the genetic diversity and ancestry of the panel. Varying levels of admixtures and distinctly divergent individuals were observed. Estimations of genome-wide heterozygosity revealed that, on average, greater diversity is present in individuals with Mesoamerica (3...
March 2017: Plant Genome
https://www.readbyqxmd.com/read/28460908/gc-ms-method-to-quantify-bioavailable-phenolic-compounds-and-antioxidant-capacity-determination-of-plasma-after-acute-coffee-consumption-in-human-volunteers
#3
Oscar Javier Lara-Guzmán, Rafael Álvarez-Quintero, Edison Osorio, Mauricio Naranjo-Cano, Katalina Muñoz-Durango
Coffee, a source of chlorogenic acids (CGAs), is recognized for preventing chronic diseases associated with oxidative stress. Therefore, sensitive, selective and easy access methods for the determination of the bioavailability and antioxidant function in vivo are required in clinical studies. The aim of this work was to validate a GC/MS method to quantify caffeic acid (CA) and ferulic acid (FA) and to apply different methodologies to determine the antioxidant capacity of plasma after the acute consumption of 420mg of CGAs provided by 400mL of coffee...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28435388/amphibians-and-reptiles-of-the-state-of-chihuahua-mexico-with-comparisons-with-adjoining-states
#4
Julio A Lemos-Espinal, Geoffrey R Smith, Guillermo A Woolrich-Piña, Alexander Cruz
Chihuahua is Mexico's largest state, and its physiographic complexity affects the distribution of its herpetofauna. We list amphibians and reptiles for the state of Chihuahua, with their conservation status. We also compare this list to those of six adjoining states in the United States and Mexico (New Mexico, Texas, Coahuila, Durango, Sinaloa, and Sonora). A total of 175 species of amphibians and reptiles is found in Chihuahua. Thirty-eight are amphibians, and 137 reptiles. Chihuahuan amphibians and reptiles represent just over 37% of such species from Chihuahua and neighboring states...
2017: ZooKeys
https://www.readbyqxmd.com/read/28420209/association-between-blood-lead-levels-and-delta-aminolevulinic-acid-dehydratase-in-pregnant-women
#5
Osmel La-Llave-León, Edna M Méndez-Hernández, Francisco X Castellanos-Juárez, Eloísa Esquivel-Rodríguez, Fernando Vázquez-Alaniz, Ada Sandoval-Carrillo, Gonzalo García-Vargas, Jaime Duarte-Sustaita, Jorge L Candelas-Rangel, José M Salas-Pacheco
Blood lead levels (BLLs) and delta-aminolevulinic acid dehydratase (ALAD) activity are considered biomarkers of lead exposure and lead toxicity, respectively. The present study was designed to investigate the association between BLLs and ALAD activity in pregnant women from Durango, Mexico. A total of 633 pregnant women aged 13-43 years participated in this study. Blood lead was measured by a graphite furnace atomic absorption spectrometer. ALAD activity was measured spectrophotometrically. Mean blood lead was 2...
April 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28365226/rocky-mountain-spotted-fever-in-mexico-past-present-and-future
#6
REVIEW
Gerardo Álvarez-Hernández, Jesús Felipe González Roldán, Néstor Saúl Hernández Milan, R Ryan Lash, Casey Barton Behravesh, Christopher D Paddock
Rocky Mountain spotted fever, a tick-borne zoonosis caused by Rickettsia rickettsii, is among the most lethal of all infectious diseases in the Americas. In Mexico, the disease was first described during the early 1940s by scientists who carefully documented specific environmental determinants responsible for devastating outbreaks in several communities in the states of Sinaloa, Sonora, Durango, and Coahuila. These investigators also described the pivotal roles of domesticated dogs and Rhipicephalus sanguineus sensu lato (brown dog ticks) as drivers of epidemic levels of Rocky Mountain spotted fever...
March 29, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28264662/lack-of-association-between-toxoplasma-gondii-exposure-and-depression-in-pregnant-women-a-case-control-study
#7
Cosme Alvarado-Esquivel, Ana Liliana Martínez-Martínez, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Juan Manuel Castillo-Orona, Carlos Salas-Martínez, Antonio Sifuentes-Álvarez, Ada Agustina Sandoval-Carrillo, José M Salas-Pacheco, Oliver Liesenfeld, Elizabeth Irasema Antuna-Salcido
BACKGROUND: Very little is known about the link of T. gondii infection and depression. Through an age-, gender-, and month of pregnancy-matched case-control study, we determined the association of T. gondii infection and depression in pregnant women. METHODS: We studied 200 pregnant women with depression and 200 pregnant women without depression attended in a public hospital in Durango City, Mexico. Pregnant women were tested for the presence of anti-Toxoplasma IgG antibodies using an enzyme-linked immunoassay (EIA), and IgG seropositive women were further tested for the presence of IgM using an EIA...
March 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28246385/zeb1-regulates-multiple-oncogenic-components-involved-in-uveal-melanoma-progression
#8
Yao Chen, Xiaoqin Lu, Diego E Montoya-Durango, Yu-Hua Liu, Kevin C Dean, Douglas S Darling, Henry J Kaplan, Douglas C Dean, Ling Gao, Yongqing Liu
Human uveal melanoma (UM) is a major ocular malignant tumor with high risk of metastasis and requires multiple oncogenic factors for progression. ZEB1 is a zinc finger E-box binding transcription factor known for participating epithelial-mesenchymal transition (EMT), a critical cellular event for metastasis of malignant tumors of epithelium origin. ZEB1 is also expressed in UM and high expression of ZEB1 correlates with UM advancement, but has little effect on cell morphology. We show that spindle UM cells can become epithelioid but not vice versa; and ZEB1 exerts its tumorigenic effects by promoting cell dedifferentiation, proliferation, invasiveness, and dissemination...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28218949/the-triglyceride-and-glucose-index-is-useful-for-recognising-insulin-resistance-in-children
#9
M Rodríguez-Morán, L E Simental-Mendía, F Guerrero-Romero
AIM: Although recognising insulin resistance (IR) in children is particularly important, the gold standard test used to diagnose it, the euglyceamic glucose clamp, is costly, invasive and is not routinely available in our clinical settings in Mexico. This study evaluated whether the triglyceride-glucose (TyG) index would provide a useful alternative. METHODS: A total of 2779 school children aged seven to 17 years, from Durango, Mexico, were enrolled during 2015-2016...
February 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28216261/modulating-the-function-of-the-immune-system-by-thyroid-hormones-and-thyrotropin
#10
REVIEW
Evelyn L Jara, Natalia Muñoz-Durango, Carolina Llanos, Carlos Fardella, Pablo A González, Susan M Bueno, Alexis M Kalergis, Claudia A Riedel
Accumulating evidence suggests a close bidirectional communication and regulation between the neuroendocrine and immune systems. Thyroid hormones (THs) can exert responses in various immune cells, e.g., monocytes, macrophages, natural killer cells, and lymphocytes, affecting several inflammation-related processes (such as, chemotaxis, phagocytosis, reactive oxygen species generation, and cytokines production). The interactions between the endocrine and immune systems have been shown to contribute to pathophysiological conditions, including sepsis, inflammation, autoimmune diseases and viral infections...
February 17, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28193849/toxoplasma-gondii-exposure-and-parkinson-s-disease-a-case-control-study
#11
Cosme Alvarado-Esquivel, Edna Madai Méndez-Hernández, José Manuel Salas-Pacheco, Luis Ángel Ruano-Calderón, Jesús Hernández-Tinoco, Oscar Arias-Carrión, Luis Francisco Sánchez-Anguiano, Francisco Xavier Castellanos-Juárez, Ada Agustina Sandoval-Carrillo, Oliver Liesenfeld, Agar Ramos-Nevárez
OBJECTIVES: To determine the association between Toxoplasma gondii infection and Parkinson's disease and to investigate whether T. gondii seropositivity is associated with the general characteristics of patients with Parkinson's disease. DESIGN: Case-control study. SETTING: Cases and controls were enrolled in Durango City, Mexico. PARTICIPANTS: 65 patients with Parkinson's disease and 195 age- and gender-matched control subjects without Parkinson's disease...
February 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/27927239/the-relationship-between-blood-lead-levels-and-occupational-exposure-in-a-pregnant-population
#12
Osmel La-Llave-León, José Manuel Salas Pacheco, Sergio Estrada Martínez, Eloísa Esquivel Rodríguez, Francisco X Castellanos Juárez, Ada Sandoval Carrillo, Angélica María Lechuga Quiñones, Fernando Vázquez Alanís, Gonzalo García Vargas, Edna Madai Méndez Hernández, Jaime Duarte Sustaita
BACKGROUND: Pregnant women exposed to lead are at risk of suffering reproductive damages, such as miscarriage, preeclampsia, premature delivery and low birth weight. Despite that the workplace offers the greatest potential for lead exposure, there is relatively little information about occupational exposure to lead during pregnancy. This study aims to assess the association between blood lead levels and occupational exposure in pregnant women from Durango, Mexico. METHODS: A cross-sectional study was carried out in a population of 299 pregnant women...
December 7, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27925206/opposite-effects-of-mechanical-action-of-fluid-flow-on-proangiogenic-factor-secretion-from-human-adipose-derived-stem-cells-with-and-without-oxidative-stress
#13
Beatriz Bravo, Cira García de Durango, Álvaro González, Arancha R Gortázar, Xavier Santos, Jerónimo Forteza-Vila, Fernando Vidal-Vanaclocha
Mechanical forces, hypoxia, and oxidative stress contribute to skin renewal, perfusion, and wound healing, but how are they regulating subcutaneous adipose-derived stem cells (ASCs) in the inflammatory microenvironment associated to skin repair and disorders is unknown. In this study, ASCs were isolated from lipoaspirate samples from plastic surgery patients, primary cultured and their differentiation and secretion of a panel of cytokines with pronounced effects on skin repair and angiogenesis were studied under mechanical stimulation by intermittent fluid flow, 1% hypoxia and oxidative stress by glutathione (GSH) depletion with buthionine sulfoximine (BSO) treatment...
August 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/27902795/genome-wide-association-study-identifies-candidate-loci-underlying-agronomic-traits-in-a-middle-american-diversity-panel-of-common-bean
#14
Samira Mafi Moghaddam, Sujan Mamidi, Juan M Osorno, Rian Lee, Mark Brick, James Kelly, Phillip Miklas, Carlos Urrea, Qijian Song, Perry Cregan, Jane Grimwood, Jeremy Schmutz, Phillip E McClean
Common bean ( L.) breeding programs aim to improve both agronomic and seed characteristics traits. However, the genetic architecture of the many traits that affect common bean production are not completely understood. Genome-wide association studies (GWAS) provide an experimental approach to identify genomic regions where important candidate genes are located. A panel of 280 modern bean genotypes from race Mesoamerica, referred to as the Middle American Diversity Panel (MDP), were grown in four US locations, and a GWAS using >150,000 single-nucleotide polymorphisms (SNPs) (minor allele frequency [MAF] ≥ 5%) was conducted for six agronomic traits...
November 2016: Plant Genome
https://www.readbyqxmd.com/read/27853117/assessing-the-archaeoparasitological-potential-of-quids-as-a-source-material-for-immunodiagnostic-analyses
#15
Johnica J Morrow, Karl J Reinhard
In the present study, quids from La Cueva de los Muertos Chiquitos (CMC) were subjected to ELISA tests for 2 protozoan parasites, Toxoplasma gondii (n=45) and Trypanosoma cruzi (n=43). The people who occupied CMC, the Loma San Gabriel, lived throughout much of present-day Durango and Zacatecas in Mexico. The known pathoecology of these people puts them into at-risk categories for the transmission of T. gondii and T. cruzi. Human antibodies created in response to these 2 parasites can be detected in modern saliva using ELISA kits intended for use with human serum...
October 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/27829953/high-prevalence-of-toxoplasma-gondii-infection-in-miners-a-case-control-study-in-rural-durango-mexico
#16
Cosme Alvarado-Esquivel, Sandy Janet Pacheco-Vega, Jesus Hernandez-Tinoco, Luis Omar Berumen-Segovia, Luis Francisco Sanchez-Anguiano, Sergio Estrada-Martinez, Ada Agustina Sandoval-Carrillo, Jose Manuel Salas-Pacheco, Oliver Liesenfeld, Elizabeth Irasema Antuna-Salcido
BACKGROUND: Very little is known about the seroepidemiology of infection with the parasite Toxoplasma gondii (T. gondii) in miners. We determine the association of T. gondii infection and the occupation of miner, and the association of seropositivity for T. gondii with the socio-demographic, clinical, work and behavioral characteristics of the miners. METHODS: Through a case-control study, 125 miners working in Durango State, Mexico and 250 age- and gender-matched non-miner subjects were examined for the presence of anti-T...
December 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27813116/distinct-osteomimetic-response-of-androgen-dependent-and-independent-human-prostate-cancer-cells-to-mechanical-action-of-fluid-flow-prometastatic-implications
#17
Álvaro González, Cira García de Durango, Verónica Alonso, Beatriz Bravo, Arancha Rodríguez de Gortázar, Alan Wells, Jerónimo Forteza, Fernando Vidal-Vanaclocha
BACKGROUND AND METHODS: Prostate cancer frequently expresses an osteomimetic phenotype, but it is unclear how it is regulated and what biological and clinical implications it confers. Because mechanical forces physiologically regulate bone-remodeling activity in osteocytes, we hypothesized that mechanical action of fluid flow (MAFF) at the cancer microenvironment may similarly foster prostate cancer cell osteomimicry. RESULTS: We showed that in vitro MAFF on androgen-dependent (LNCap) and androgen-independent (PC3) prostate cancer cells remarkably increased OPG, VEGF, RunX2, PTH1R, and PTHrP gene expression in both cell lines irrespective of their androgen dependency...
November 3, 2016: Prostate
https://www.readbyqxmd.com/read/27745657/mercury-uptake-and-effects-on-growth-in-jatropha-curcas
#18
José Marrugo-Negrete, José Durango-Hernández, José Pinedo-Hernández, Germán Enamorado-Montes, Sergi Díez
The use of metal-accumulating plants for the phytoremediation of contaminated soils is gaining more attention. Mercury (Hg)-contaminated soils from historical gold mines represent a potential risk to human health and the environment. Therefore, Jatropha curcas plant, that has shown its tolerance to these environments, is a species of particular interest to implement phytoremediation techniques in gold mining sites. In this work, the behavior of J. curcas was assessed in different hydroponic cultures fortified with Hg at concentrations of 5, 10, 20, 40, and 80μgHg/mL (T5, T10, T20, T40 and T80, respectively)...
October 2016: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/27721129/removal-of-mercury-from-gold-mine-effluents-using-limnocharis-flava-in-constructed-wetlands
#19
José Marrugo-Negrete, Germán Enamorado-Montes, José Durango-Hernández, José Pinedo-Hernández, Sergi Díez
Phytoremediation has received increased attention over the recent decades, as an emerging and eco-friendly approach that utilizes the natural properties of plants to remediate contaminated water, soils or sediments. The current study provides information about a pilot-scale experiment designed to evaluate the potential of the anchored aquatic plant Limnocharis flava for phytoremediation of water contaminated with mercury (Hg), in a constructed wetland (CW) with horizontal subsurface flow (HSSF). Mine effluent used in this experiment was collected from a gold mining area located at the Alacran mine in Colombia (Hg: 0...
January 2017: Chemosphere
https://www.readbyqxmd.com/read/27692608/endothelial-to-mesenchymal-transition-cytokine-mediated-pathways-that-determine-endothelial-fibrosis-under-inflammatory-conditions
#20
Lorena Pérez, Natalia Muñoz-Durango, Claudia A Riedel, Cesar Echeverría, Alexis M Kalergis, Claudio Cabello-Verrugio, Felipe Simon
During the last decade, the endothelial-to-mesenchymal transition (EndMT) process has attracted considerable attention due to associations with the onset of certain diseases, such as organ fibrosis and cancer. Several studies have assessed the mechanisms and signaling pathways that regulate endothelial fibrosis in the context of human pathologies. A number of inflammatory mediators, including pro-inflammatory cytokines, growth factors, oxidative stress, and toxins, induce the conversion of endothelial cells into mesenchymal fibroblast-like cells that promote disease progression...
September 23, 2016: Cytokine & Growth Factor Reviews
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