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https://www.readbyqxmd.com/read/27925206/opposite-effects-of-mechanical-action-of-fluid-flow-on-proangiogenic-factor-secretion-from-human-adipose-derived-stem-cells-with-and-without-oxidative-stress
#1
Beatriz Bravo, Cira García de Durango, Álvaro González, Arancha R Gortázar, Xavier Santos, Jerónimo Forteza-Vila, Fernando Vidal-Vanaclocha
Mechanical forces, hypoxia and oxidative stress contribute to skin renewal, perfusion and wound healing, but how are they regulating subcutaneous adipose-derived stem cells (ASCs) in the inflammatory microenvironment associated to skin repair and disorders is unknown. In this study, ASCs were isolated from lipoaspirate samples from plastic surgery patients, primary cultured and their differentiation and secretion of a panel of cytokines with pronounced effects on skin repair and angiogenesis were studied under mechanical stimulation by intermittent fluid flow, 1% hypoxia and oxidative stress by glutathione (GSH) depletion with buthionine sulfoximine (BSO) treatment...
December 7, 2016: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/27902795/genome-wide-association-study-identifies-candidate-loci-underlying-agronomic-traits-in-a-middle-american-diversity-panel-of-common-bean
#2
Samira Mafi Moghaddam, Sujan Mamidi, Juan M Osorno, Rian Lee, Mark Brick, James Kelly, Phillip Miklas, Carlos Urrea, Qijian Song, Perry Cregan, Jane Grimwood, Jeremy Schmutz, Phillip E McClean
Common bean ( L.) breeding programs aim to improve both agronomic and seed characteristics traits. However, the genetic architecture of the many traits that affect common bean production are not completely understood. Genome-wide association studies (GWAS) provide an experimental approach to identify genomic regions where important candidate genes are located. A panel of 280 modern bean genotypes from race Mesoamerica, referred to as the Middle American Diversity Panel (MDP), were grown in four US locations, and a GWAS using >150,000 single-nucleotide polymorphisms (SNPs) (minor allele frequency [MAF] ≥ 5%) was conducted for six agronomic traits...
November 2016: Plant Genome
https://www.readbyqxmd.com/read/27853117/assessing-the-archaeoparasitological-potential-of-quids-as-a-source-material-for-immunodiagnostic-analyses
#3
Johnica J Morrow, Karl J Reinhard
In the present study, quids from La Cueva de los Muertos Chiquitos (CMC) were subjected to ELISA tests for 2 protozoan parasites, Toxoplasma gondii (n=45) and Trypanosoma cruzi (n=43). The people who occupied CMC, the Loma San Gabriel, lived throughout much of present-day Durango and Zacatecas in Mexico. The known pathoecology of these people puts them into at-risk categories for the transmission of T. gondii and T. cruzi. Human antibodies created in response to these 2 parasites can be detected in modern saliva using ELISA kits intended for use with human serum...
October 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/27829953/high-prevalence-of-toxoplasma-gondii-infection-in-miners-a-case-control-study-in-rural-durango-mexico
#4
Cosme Alvarado-Esquivel, Sandy Janet Pacheco-Vega, Jesus Hernandez-Tinoco, Luis Omar Berumen-Segovia, Luis Francisco Sanchez-Anguiano, Sergio Estrada-Martinez, Ada Agustina Sandoval-Carrillo, Jose Manuel Salas-Pacheco, Oliver Liesenfeld, Elizabeth Irasema Antuna-Salcido
BACKGROUND: Very little is known about the seroepidemiology of infection with the parasite Toxoplasma gondii (T. gondii) in miners. We determine the association of T. gondii infection and the occupation of miner, and the association of seropositivity for T. gondii with the socio-demographic, clinical, work and behavioral characteristics of the miners. METHODS: Through a case-control study, 125 miners working in Durango State, Mexico and 250 age- and gender-matched non-miner subjects were examined for the presence of anti-T...
December 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27813116/distinct-osteomimetic-response-of-androgen-dependent-and-independent-human-prostate-cancer-cells-to-mechanical-action-of-fluid-flow-prometastatic-implications
#5
Álvaro González, Cira García de Durango, Verónica Alonso, Beatriz Bravo, Arancha Rodríguez de Gortázar, Alan Wells, Jerónimo Forteza, Fernando Vidal-Vanaclocha
BACKGROUND AND METHODS: Prostate cancer frequently expresses an osteomimetic phenotype, but it is unclear how it is regulated and what biological and clinical implications it confers. Because mechanical forces physiologically regulate bone-remodeling activity in osteocytes, we hypothesized that mechanical action of fluid flow (MAFF) at the cancer microenvironment may similarly foster prostate cancer cell osteomimicry. RESULTS: We showed that in vitro MAFF on androgen-dependent (LNCap) and androgen-independent (PC3) prostate cancer cells remarkably increased OPG, VEGF, RunX2, PTH1R, and PTHrP gene expression in both cell lines irrespective of their androgen dependency...
November 3, 2016: Prostate
https://www.readbyqxmd.com/read/27745657/mercury-uptake-and-effects-on-growth-in-jatropha-curcas
#6
José Marrugo-Negrete, José Durango-Hernández, José Pinedo-Hernández, Germán Enamorado-Montes, Sergi Díez
The use of metal-accumulating plants for the phytoremediation of contaminated soils is gaining more attention. Mercury (Hg)-contaminated soils from historical gold mines represent a potential risk to human health and the environment. Therefore, Jatropha curcas plant, that has shown its tolerance to these environments, is a species of particular interest to implement phytoremediation techniques in gold mining sites. In this work, the behavior of J. curcas was assessed in different hydroponic cultures fortified with Hg at concentrations of 5, 10, 20, 40, and 80μgHg/mL (T5, T10, T20, T40 and T80, respectively)...
October 2016: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/27721129/removal-of-mercury-from-gold-mine-effluents-using-limnocharis-flava-in-constructed-wetlands
#7
José Marrugo-Negrete, Germán Enamorado-Montes, José Durango-Hernández, José Pinedo-Hernández, Sergi Díez
Phytoremediation has received increased attention over the recent decades, as an emerging and eco-friendly approach that utilizes the natural properties of plants to remediate contaminated water, soils or sediments. The current study provides information about a pilot-scale experiment designed to evaluate the potential of the anchored aquatic plant Limnocharis flava for phytoremediation of water contaminated with mercury (Hg), in a constructed wetland (CW) with horizontal subsurface flow (HSSF). Mine effluent used in this experiment was collected from a gold mining area located at the Alacran mine in Colombia (Hg: 0...
October 5, 2016: Chemosphere
https://www.readbyqxmd.com/read/27692608/endothelial-to-mesenchymal-transition-cytokine-mediated-pathways-that-determine-endothelial-fibrosis-under-inflammatory-conditions
#8
Lorena Pérez, Natalia Muñoz-Durango, Claudia A Riedel, Cesar Echeverría, Alexis M Kalergis, Claudio Cabello-Verrugio, Felipe Simon
During the last decade, the endothelial-to-mesenchymal transition (EndMT) process has attracted considerable attention due to associations with the onset of certain diseases, such as organ fibrosis and cancer. Several studies have assessed the mechanisms and signaling pathways that regulate endothelial fibrosis in the context of human pathologies. A number of inflammatory mediators, including pro-inflammatory cytokines, growth factors, oxidative stress, and toxins, induce the conversion of endothelial cells into mesenchymal fibroblast-like cells that promote disease progression...
September 23, 2016: Cytokine & Growth Factor Reviews
https://www.readbyqxmd.com/read/27562126/oxidative-stress-equilibrium-during-obstetric-event-in-normal-pregnancy
#9
Jose Manuel Salas-Pacheco, Diana Lelidett Lourenco-Jaramillo, Edna Madai Mendez-Hernandez, Ada Agustina Sandoval-Carrillo, Yessica Ivonne Hernandez Rayon, Osmel La Llave-Leon, Marisela Aguilar-Duran, Marcos Alonso Lopez-Terrones, Marcelo Barraza-Salas, Fernando Vazquez-Alaniz
OBJECTIVE: The aim of this study was to determine malondialdehyde (MDA) concentration as an oxidative stress marker and total antioxidant capacity (TAC) in pregnancy before and after perinatal event. METHODS: This study was performed on 200 healthy full-term pregnant women admitted to pregnancy resolution in Maternal-Child Hospital of Durango, Mexico. Oxidative stress and total antioxidant capacity were assessed through detection of lipid peroxidation by quantitation of thiobarbituric acid-reactive substances (TBARS) and total antioxidant capacity (TAC) through ferric reducing ability of the plasma (FRAP) Results: Our results showed increased levels of MDA after vaginal delivery...
August 25, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27540439/rubella-immune-status-in-pregnant-women-in-a-northern-mexican-city
#10
Cosme Alvarado-Esquivel, Jesus Hernandez-Tinoco, Luis Francisco Sanchez-Anguiano, Agar Ramos-Nevarez, Sandra Margarita Cerrillo-Soto, Jose Manuel Salas-Pacheco, Ada Agustina Sandoval-Carrillo, Lucio Martinez-Ramirez, Elizabeth Irasema Antuna-Salcido, Carlos Alberto Guido-Arreola
BACKGROUND: The seroepidemiology of rubella virus infection in pregnant women in northern Mexico is largely unknown. We sought to determine the seroprevalence of rubella virus infection in pregnant women in the northern Mexican city of Durango, Mexico. Seroprevalence association with the socio-demographic, clinical and behavioral characteristics of the pregnant women was also investigated. METHODS: Through a cross-sectional study, we determined the seroprevalence of IgG and IgM anti-rubella virus in 279 pregnant women (mean age 29...
September 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27429791/seroepidemiology-of-toxoplasma-gondii-infection-in-people-applying-for-medical-certificates
#11
Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Rosa Angélica Pulido-Montoya, Guadalupe Acosta-Rojas, Sergio Estrada-Martínez, Alma Rosa Pérez-Álamos, Raquel Vaquera-Enriquez, Arturo Díaz-Herrera, Raúl Segura-Moreno, María de Lourdes Guerrero-Carbajal, Oliver Liesenfeld, Isabel Beristain García, María Guadalupe Rentería-López
Medical certificates are documents that state the health status of a person. This study aimed to determine the seroprevalence and risk factors for Toxoplasma gondii infection in applicants of medical certificates and to investigate seroprevalence association with characteristics of these individuals. We examined 404 applicants in a public health center in Durango City, Mexico for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays. Of the 404 subjects (mean age of 35.94 ± 13...
June 24, 2016: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/27429790/toxoplasma-gondii-infection-and-depression-a-case-control-seroprevalence-study
#12
Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Luis Omar Berumen-Segovia, Yazmin Elizabeth Torres-Prieto, Sergio Estrada-Martínez, Alma Rosa Pérez-Álamos, María Nalleli Ortiz-Jurado, Gabriel Molotla-de-León, Isabel Beristain-García, Elizabeth Rábago-Sánchez, Oliver Liesenfeld
We assessed the association of Toxoplasma gondii infection and depression in a sample of psychiatric patients and control subjects without depression. We performed an age- and gender-matched case-control study of 89 patients suffering from depression attended in a public psychiatric hospital in Durango City, Mexico and 356 control subjects without depression from the general population of the same city. Participants were tested for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays...
June 24, 2016: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/27403273/detection-of-mental-disorders-other-than-depression-with-the-edinburgh-postnatal-depression-scale-in-a-sample-of-pregnant-women-in-northern-mexico
#13
Cosme Alvarado-Esquivel, Antonio Sifuentes-Alvarez, Carlos Salas-Martinez
We sought to evaluate the capacity of the Edinburgh Postnatal Depression Scale (EPDS) in discriminating mental disorders other than depression in pregnant women in northern Mexico. Three hundred pregnant women attending prenatal consultations in a public hospital in Durango City, Mexico submitted a validated EPDS and were examined for mental disorders other than depression using the Diagnostic and Statistical Manual of Mental Disorders - 4(th) Ed. (DSM-IV) criteria. Sensitivity and specificity of cut-off points of the EPDS, and positive and negative predictive values were calculated...
May 18, 2016: Mental Illness
https://www.readbyqxmd.com/read/27357886/self-perceived-discrimination-in-lgbt-population-in-oral-health-services-medellin-colombia-a-qualitative-approach
#14
Santiago Alzate-Urrea, Andres A Agudelo-Suarez, James Y Monsalve-Orrego, Flor E Londono-Candanoza, Geidy Del C Chinome-Florez, Aida L Julio-Perez, Luisa F Arias-Durango, Karen M Perez-Torres
INTRODUCTION: We aim to understand the perception about discrimination within the LGBT population when accessing oral health services, from their perspective as well as that of the oral health professional. METHODS: A qualitative study from a phenomenological perspective was conducted by means of 37 in-depth interwiews (19 in health service providers and 18 in LGBT members). The script used in the interview included questions related to discrimination in social spaces, quality of life and its relationship with health, access to general and oral health care and proposals and strategies...
2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27347925/role-of-the-renin-angiotensin-aldosterone-system-beyond-blood-pressure-regulation-molecular-and-cellular-mechanisms-involved-in-end-organ-damage-during-arterial-hypertension
#15
REVIEW
Natalia Muñoz-Durango, Cristóbal A Fuentes, Andrés E Castillo, Luis Martín González-Gómez, Andrea Vecchiola, Carlos E Fardella, Alexis M Kalergis
Arterial hypertension is a common condition worldwide and an important predictor of several complicated diseases. Arterial hypertension can be triggered by many factors, including physiological, genetic, and lifestyle causes. Specifically, molecules of the renin-angiotensin-aldosterone system not only play important roles in the control of blood pressure, but they are also associated with the genesis of arterial hypertension, thus constituting a need for pharmacological interventions. Chronic high pressure generates mechanical damage along the vascular system, heart, and kidneys, which are the principal organs affected in this condition...
2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27311164/-risk-factors-associated-with-breast-cancer-women-s-in-durango-mexico
#16
Antonio Sifuentes-Álvarez, Lucy Yolanda Castañeda-Martínez, Mario Lugo-Nevares, Miguel Arturo Reyes-Romero
BACKGROUND: Breast cancer is a public health problem worldwide and is a priority for developing countries like ours, to establish preventive and early detection measures. In Mexico since 2006 breast cancer than cervical cancer as a cause of death in women aged 30-54 years and threatens all socioeconomic groups. The known risk factors for the occurrence of this neoplasm are early menarche, nulliparity, late age parity and late menopause and family history of breast cancer. OBJECTIVE: To determine the risk factors associated with breast cancer in women in the State of Durango...
November 2015: Ginecología y Obstetricia de México
https://www.readbyqxmd.com/read/27298660/toxoplasma-gondii-infection-and-mixed-anxiety-and-depressive-disorder-a-case-control-seroprevalence-study-in-durango-mexico
#17
Cosme Alvarado-Esquivel, Luis Francisco Sanchez-Anguiano, Jesus Hernandez-Tinoco, Luis Omar Berumen-Segovia, Yazmin Elizabeth Torres-Prieto, Sergio Estrada-Martinez, Alma Rosa Perez-Alamos, Maria Nalleli Ortiz-Jurado, Gabriel Molotla-de-Leon, Isabel Beristain Garcia, Elizabeth Rabago-Sanchez, Oliver Liesenfeld
BACKGROUND: The parasite Toxoplasma gondii (T. gondii) may invade the brain and might induce behavioral changes. We sought to determine the association of T. gondii infection and mixed anxiety and depressive disorder. METHODS: Through an age- and gender-matched case-control seroprevalence study, we examined 65 patients suffering from mixed anxiety and depressive disorder (WHO ICD-10 code: F41.2) attending in a public hospital of mental health and 260 control subjects without this disorder from the general population...
July 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27187775/burnout-syndrome-in-first-to-sixth-year-medical-students-at-a-private-university-in-the-north-of-mexico-descriptive-cross-sectional-study
#18
Laura Asencio-López, Guillermo Daniel Almaraz-Celis, Vicente Carrillo Maciel, Paola Huerta Valenzuela, Luis Silva Goytia, Marcos Muñoz Torres, Fernando Monroy Caballero, Joel Regalado Tapia, Kerigma Dipp Martin, Dinorah López Miranda, Clyvia Medina Lavenant, Karen Pizarro Rodríguez, Cesar Santiago Martínez, Alma Geovanna Saucedo Aparicio, Rodolfo Flores Lepe
INTRODUCTION: Burnout syndrome is a three-dimensional clinical syndrome caused by stress at work. It is frequent in professions which require direct contact with people. In Mexico, the presence of Burnout Syndrome in doctors and medical students, is characterized as a threat to their health, quality of life and professional performance. OBJECTIVES: To evaluate the prevalence of burnout syndrome in students of years 1 through 6 of medical school at a private university in northern Mexico...
2016: Medwave
https://www.readbyqxmd.com/read/27141314/influence-of-toxoplasma-gondii-infection-on-symptoms-and-signs-of-menopause
#19
Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Edwin Adiel Calzada-Torres, Sergio Estrada-Martínez, Alma Rosa Pérez-Álamos, Raquel Vaquera-Enriquez, Arturo Díaz-Herrera, Raúl Segura-Moreno, María de Lourdes Guerrero-Carbajal, María Guadalupe Rentería-López, Isabel Beristain García, Elizabeth Rábago-Sánchez, Oliver Liesenfeld
Some symptoms of menopause have also been described in patients with toxoplasmosis. Whether Toxoplasma gondii (T. gondii) infection has any influence on clinical manifestations of menopause is yet unknown. We sought to determine whether T. gondii exposure is associated with symptoms and signs of menopause. We performed a cross-sectional study of women attending a public health center in Durango City, Mexico. Participants were examined for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays...
March 2016: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/27127452/unhappiness-with-the-fetal-gender-is-associated-with-depression-in-adult-pregnant-women-attending-prenatal-care-in-a-public-hospital-in-durango-mexico
#20
Cosme Alvarado-Esquivel, Antonio Sifuentes-Alvarez, Carlos Salas-Martinez
Depression during pregnancy has been scantily studied in Mexican women. We aimed to determine the prevalence and correlates of depression in adult pregnant women attending a public hospital in the northern Mexican city of Durango, Mexico. Through a cross-sectional study design, we assessed depression in 270 adult pregnant women attended for prenatal care in a public hospital using a validated Mexican version of the Edinburg Postnatal Depression Scale in pregnancy and further confirmation by a psychiatric evaluation using the DSM-IV criteria for depression...
March 2016: International Journal of Biomedical Science: IJBS
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