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Medically unexplained symptoms

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https://www.readbyqxmd.com/read/29148230/personality-traits-such-as-neuroticism-and-disability-predict-psychological-distress-in-medically-unexplained-symptoms-a-three-year-experience-from-a-single-centre
#1
Vikas Menon, Balasubramanian Shanmuganathan, Jaiganesh Selvapandian Thamizh, Anand Babu Arun, Pooja Patnaik Kuppili, Siddharth Sarkar
BACKGROUND: People with medically unexplained symptoms (MUS) may have psychological co-morbidities. AIMS: Our objectives were to assess the rates and identify correlates of psychological distress in MUS. METHODS: A total of 171 subjects with MUS seeking treatment at a tertiary care facility were assessed over a 3-year period. Psychological distress was assessed using the Tamil version of General Health Questionnaire-12. Apart from socio-demographic factors, personality, coping, perceived social support and subjective disability were assessed using standard instruments...
November 17, 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/29140276/clinical-profile-associated-with-adverse-childhood-experiences-the-advent-of-nervous-system-dysregulation
#2
Jorina Elbers, Cynthia R Rovnaghi, Brenda Golianu, Kanwaljeet J S Anand
BACKGROUND: We report the prevalence of children with multiple medical symptoms in a pediatric neurology clinic, describe their symptom profiles, and explore their association with adverse childhood experiences (ACEs). METHODS: We retrospectively reviewed 100 consecutive patients from an outpatient pediatric neurology clinic. Patients were included if they were ≥5 years old and reported ≥4 symptoms that were unexplained for ≥3-months. Symptom profiles across six functional domains were recorded: (1) executive dysfunction, (2) sleep disturbances, (3) autonomic dysregulation, (4) somatization, (5) digestive symptoms, and (6) emotional dysregulation...
November 15, 2017: Children
https://www.readbyqxmd.com/read/29132773/-maternal-deaths-due-to-sudden-death-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#3
E Morau, E Beaumont, E Verspyck
Sudden death is defined as unexpected cardiac arrest occurring less than one hour after the onset of the first symptoms. Between 2010 and 2012, 23 maternal deaths were considered as unexplained sudden deaths and three of them were not evaluated due to a lack of clinical data. In addition, 13 maternal deaths with an identified cause occurred in a clinical context of sudden death (7 cases of pulmonary embolism, 2 cases of epilepsy, and 2 cases of cardiomyopathy). The first maneuvers of resuscitation in the presence of bystanders were attempted in 8 of 22 cases (36%)...
November 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29098971/-the-prognosis-of-medically-unexplained-symptoms
#4
D J C Hanssen, H Knoop, J G M Rosmalen
- The condition where someone has physical symptoms for a number of weeks for which no clear somatic cause can be found, is known as medically unexplained symptoms (MUS).- In this article we give an overview of current insights into the prognosis of MUS.- Extensive somatic testing in patients diagnosed with MUS by a physician, rarely results in a somatic diagnosis.- In approximately half of these patients, MUS disappear spontaneously within one year.- Symptom-related characteristics - such as experiencing multiple physical symptoms simultaneously-, and psychological characteristics - such as unhelpful thoughts - are predictors of an unfavourable prognosis for MUS...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29096941/the-neuropsychophysiology-of-tingling
#5
REVIEW
Benedek T Tihanyi, Eszter Ferentzi, Florian Beissner, Ferenc Köteles
Tingling is a bodily sensation experienced under a variety of conditions from everyday experiences to experimental and therapeutic situations. It can be induced by both peripheral or afferent (external stimulation, peripheral pathology) and higher cognitive (expectation) processes. The paper summarizes the current scientific knowledge on the neurophysiological and psychological concomitants of the tingling sensation. Four possible models are identified and presented: the afferent, the attention-disclosed, the attention-evoked, and the efferent model...
October 30, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/29090894/extension-of-the-presumptive-period-for-compensation-for-gulf-war-veterans-final-rule
#6
(no author information available yet)
The Department of Veterans Affairs (VA) is issuing this final rule to affirm its adjudication regulations regarding compensation for disabilities resulting from undiagnosed illnesses suffered by veterans who served in the Persian Gulf War. This amendment is necessary to extend the period during which disabilities associated with undiagnosed illnesses and medically unexplained chronic multi-symptom illnesses must become manifest in order for a Veteran to be eligible for compensation. The intended effect of this amendment is to provide consistency in VA adjudication policy, preserve certain rights afforded to Persian Gulf War (GW) veterans, and ensure fairness for current and future GW veterans...
October 24, 2017: Federal Register
https://www.readbyqxmd.com/read/29077143/-neuromodulation-can-be-effective-in-patients-with-medically-unexplained-symptoms
#7
M van Beilen, H Tieleman
BACKGROUND: Neuromodulation may influence abnormal brain activation patterns in medically unexplained symptoms (MUS). AIM: To assess the importance and direction of future studies on patients with MUS. METHOD: We describe the results of the first studies on patients with functional neurological symptom disorder (fNSD) and chronic pain. RESULTS: Clinically relevant improvements in the health condition of a substantial number of patients with fnsd have been reported...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29063801/-it%C3%A2-s-incredible-how-much-i%C3%A2-ve-had-to-fight-negotiating-medical-uncertainty-in-clinical-encounters
#8
Olaug S Lian, Catherine Robson
PURPOSE: Clinical encounters related to medically unexplained physical symptoms (MUPS) are associated with high levels of conflict between patients and doctors. Collaborative difficulties are fused by the medical uncertainty that dominates these consultations. The main aim of this study is to explore the interactional dynamics of clinical encounters riddled by medical uncertainty, as experienced by people living with long-term medically unexplained fatigue in Norway. METHOD: A qualitative thematic analysis of written texts from 256 study participants...
2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/29050952/a-research-coding-method-to-evaluate-medical-clinicians-conduct-of-behavioral-health-care-in-patients-with-unexplained-symptoms
#9
Katelyn A Grayson-Sneed, Robert C Smith
OBJECTIVE: Develop a reliable coding method of a Behavioral Health Treatment Model for patients with Medically Unexplained Symptoms (BHTM-MUS). METHODS: Two undergraduates trained for 30h coded videotaped interviews from 161 resident-simulated patient (SP) interactions. Trained on 45 videotapes, coders coded 33 (20%) of 161 study set tapes for the BHTM-MUS. Guetzkow's U, Cohen's Kappa, and percent of agreement were used to measure coders' reliability in unitizing and coding residents' skills for eliciting: education and informing (4 yes/no items), motivating (2), treatment statements (5), commitment and goals (2), negotiates plan (8), non-emotion patient-centered skills (4), and patient-centered emotional skills (8)...
October 12, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29042939/aphasic-status-epilepticus-as-the-sole-symptom-of-epilepsy-a-case-report-and-literature-review
#10
Ji-Qing Qiu, Yu Cui, Li-Chao Sun, Zhan-Peng Zhu
Aphasia is a common symptom encountered by neurologists. However, the presence of aphasia as the sole manifestation of partial status epilepticus is rare. The present study reports a case of aphasic status epilepticus in a 27-year-old right-handed female who presented after the abrupt onset of aphasia, which had persisted for 1.5 days. The patient's medical history included head trauma followed by a craniectomy and cranioplasty. Computed tomography scans revealed a lesion in the patient's left parietal lobe, and an electroencephalogram showed a spike and slow wave pattern in the left hemisphere of the brain during aphasia...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29034324/a-review-of-epidemiologic-studies-of-the-health-of-gulf-war-women-veterans
#11
Steven S Coughlin, Maxine Krengel, Kimberly Sullivan, Penny F Pierce, Vahé Heboyan, Lt Col Candy Wilson
INTRODUCTION: In the 25 years since the 1990-1991 Gulf War (GW), studies have evaluated Gulf War Illness (GWI), sometimes referred to as medically unexplained multi symptom illness, and other medical and neurological conditions in women GW veterans. MATERIALS AND METHODS: In this article, we review epidemiologic studies of the health of women who served in the 1990-1991 GW based upon bibliographic searches in PubMed and CINAHL with relevant search terms through September 2015...
2017: Journal of Environment and Health Sciences
https://www.readbyqxmd.com/read/29019415/pain-characteristics-of-older-persons-with-medically-unexplained-symptoms-older-persons-with-medically-explained-symptoms-and-older-persons-with-depression
#12
Denise J C Hanssen, Peter L B J Lucassen, Paul Naarding, Margot W M de Waal, Richard C Oude Voshaar
OBJECTIVES: The main objective of the current study is to compare chronic pain characteristics of older patients with Medically Unexplained Symptoms (MUS), to those of patients with Medically Explained Symptoms (MES), and to those of patients with Major Depressive Disorder (MDD). METHOD: By combining data from the OPUS and NESDO study, we compared pain characteristics of 102 older (>60 years) MUS-patients to 145 older MES-patients and 275 older MDD-patients in a case-control study design...
October 11, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29018561/disturbed-eeg-sleep-paranoid-cognition-and-somatic-symptoms-identify-veterans-with-post-traumatic-stress-disorder
#13
Harvey Moldofsky, Lorne Rothman, Robert Kleinman, Shawn G Rhind, J Donald Richardson
BACKGROUND: Chronic post-traumatic stress disorder (PTSD) behavioural symptoms and medically unexplainable somatic symptoms are reported to occur following the stressful experience of military combatants in war zones. AIMS: To determine the contribution of disordered EEG sleep physiology in those military combatants who have unexplainable physical symptoms and PTSD behavioural difficulties following war-zone exposure. METHOD: This case-controlled study compared 59 veterans with chronic sleep disturbance with 39 veterans with DSM-IV and clinician-administered PTSD Scale diagnosed PTSD who were unresponsive to pharmacological and psychological treatments...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/28985688/diagnosis-and-management-of-pancreatic-exocrine-insufficiency-pei-in-primary-care-consensus-guidance-of-a-canadian-expert-panel
#14
P Durie, J-D Baillargeon, S Bouchard, F Donnellan, S Zepeda-Gomez, C Teshima
Pancreatic exocrine insufficiency (PEI) results in maldigestion due to inadequate activity of pancreatic enzymes in the small bowel. PEI can arise from a variety of medical conditions that reduce enzyme synthesis within the pancreatic parenchyma or from secondary factors that may occur despite optimal parenchymal function, such as pancreatic duct obstruction or reduced or poorly synchronized enzyme release. The most characteristic symptom of PEI is steatorrhea - voluminous, lipid-rich stools; other common signs and symptoms include unexplained weight loss and deficiencies of fat-soluble vitamins and other micronutrients...
October 6, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28918724/why-medically-unexplained-symptoms-and-health-anxiety-don-t-need-to-make-your-heart-sink
#15
Jill M Newby, Gavin Andrews
No abstract text is available yet for this article.
June 19, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28899390/-if-it-s-a-medical-issue-i-would-have-covered-it-by-now-learning-about-fibromyalgia-through-the-hidden-curriculum-a-qualitative-study
#16
V Silverwood, C A Chew-Graham, I Raybould, B Thomas, S Peters
BACKGROUND: Fibromyalgia syndrome (FMS) is a long-term condition that affects between 1 and 5% of the general population and lies within the spectrum of medically unexplained symptoms (MUS). FMS can be difficult to diagnose and is usually done so as a diagnosis of exclusion. There is continuing debate regarding its legitimacy excluding other causes of symptoms. It is known that the diagnosis and management of MUS, including FMS, receives little attention in medical curricula and attitudes towards patients with FMS amongst medical professionals and trainees can be negative...
September 12, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28895496/coherent-care-pathways-for-medically-unexplained-symptoms
#17
Itoro Udo, Iniobong Udo
No abstract text is available yet for this article.
September 2017: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/28895486/iatrogenic-adrenal-insufficiency-secondary-to-combination-therapy-with-elvitegravir-cobicistat-tenofovir-disoproxil-fumarate-emtricitabine-and-interlaminar-triamcinolone-injection-in-an-aids-patient
#18
Chanie Wassner, Sutapa Maiti, Kurt Kodroff, Henry Cohen
We report the first identified case of suspected iatrogenic adrenal insufficiency after an interlaminar injection of triamcinolone acetonide while on concomitant Stribild (elvitegravir 150 mg/cobicistat 150 mg/tenofovir disoproxil fumarate 300 mg/emtricitabine 200 mg [EVG/c/TDF/FTC]). A 49-year-old female with HIV on EVG/c/TDF/FTC therapy presented to our endocrinology clinic to be evaluated for suspected Cushing syndrome. Prior to presentation, the patient had been given 2 interlaminar spinal injections of triamcinolone...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28867416/negative-affect-as-mediator-between-emotion-regulation-and-medically-unexplained-symptoms
#19
Jeanine Schwarz, Winfried Rief, Anna Radkovsky, Matthias Berking, Maria Kleinstäuber
BACKGROUND: Research on emotion regulation (ER) in medically unexplained physical symptoms (MUS) is rare. PURPOSE: The goal of this study was to compare ER skills between MUS-patients without comorbid depression, MUS-patients with comorbid depression (MUS+MDD), patients with major depressive disorder (MDD), and healthy controls. Additionally, we examined the mediating effect of depression and anxiety on the relationship between ER and somatization. METHODS: The Emotion-Regulation Skills Questionnaire (ERSQ) and other self-report measures were completed by 138 MUS-patients, 114 MUS+MDD-patients, 106 MDD-patients, and 100 healthy controls...
October 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28860774/bipolar-ii-disorder-as-the-initial-presentation-of-cadasil-an-underdiagnosed-manifestation
#20
Jianjun Wang, Jinfang Li, Fanxin Kong, Hanqing Lv, Zhouke Guo
Mood disturbances have been documented in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). The highly varied morbidity indicates that the affective symptoms in CADASIL have not been cataloged systematically, leading to ineffective treatment, affecting the patients' quality of life, and possibly resulting in suicide. We present a case of CADASIL with bipolar II disorder as the first manifestation. A middle-aged female reported recurrent depressive episodes and appeared treatment resistant to adequate dosages and durations of antidepressants...
2017: Neuropsychiatric Disease and Treatment
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