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https://www.readbyqxmd.com/read/28319384/eugenol-nanoemulsion-stabilized-with-zein-and-sodium-caseinate-by-self-assembly
#1
Lei Wang, Yue Zhang
Eugenol-loaded nanoemulsion by zein and sodium caseinate (NaCas) was prepared without using specific equipment or organic solvents. The deprotonated eugenol in hot alkaline was added into NaCas/zein mixtures with different mass ratios at pH 11.5, and then neutralized to pH 7.0. The nanoemulsions showed well-defined diameter (around 109-139 nm) and negative surface potential (-28.5~ -35.8 mv). The entrapment efficiency (EE) of 1% v/v eugenol reached 84.24% by 2% m/v NaCas/zein at a mass ratio of 1:1. This formulation also showed the narrowest size distribution, extraordinary stability during ambient storage (22 oC) up to 30 days, and retained good re-dispersiblity after spray- or freeze- drying...
March 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28301018/physicochemical-properties-and-dentin-bond-strength-of-a-tricalcium-silicate-based-retrograde-material
#2
Camila de Paula Telles Pires Lucas, Raqueli Viapiana, Roberta Bosso-Martelo, Juliane Maria Guerreiro-Tanomaru, Josette Camilleri, Mário Tanomaru-Filho
The aim of this study was to evaluate the physicochemical properties and the apical dentin bond strength of the tricalcium silicate-based Biodentine in comparison to white MTA and zinc oxide eugenol-based cement (ZOE). Setting time and radiopacity were evaluated according to ISO 6876:2012 specification. Final setting time, compressive strength and pH were also assessed. Material's bond strength to the apical root canal dentin was measured by the push-out assay. Data were analyzed by ANOVA and Tukey-Krammer post-hoc test...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28294554/sequential-functionalization-of-a-natural-crosslinker-leads-to-designer-silicone-networks
#3
Scott E Laengert, Alyssa F Schneider, Yang Chen, Michael A Brook
Precise silicone networks are difficult to prepare from multiple starting materials because of poor special control over crosslink location, competing side reactions, and incompatible catalysts among other reasons. We demonstrate that cure processes catalyzed by B(C6F5)3 (the Piers-Rubinsztajn reaction) and platinum-catalyzed hydrosilylation are perfectly compatible, and can be used in either order. It is possible to perform three different, selective, sequential reactions in the same pot using H-terminated silicones as chain extenders in all cases to give explicit networks...
March 10, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28292339/comparison-of-ferric-sulfate-combined-mineral-trioxide-aggregate-pulpotomy-and-zinc-oxide-eugenol-pulpectomy-of-primary-maxillary-incisors-an-18-month-randomized-controlled-trial
#4
Trang D Nguyen, Peter L Judd, Edward J Barrett, Nicole Sidhu, Michael J Casas
PURPOSE: The purpose of this study was to compare outcomes and survival of ferric sulfate with mineral trioxide aggregate (FS+MTA) pulpotomy and root canal therapy (RCT) in carious vital primary maxillary incisors. METHODS: In this parallel group noninferiority trial, asymptomatic carious vital primary incisors with pulp exposure in healthy 18- to 46-month-olds were allocated randomly to receive FS+MTA pulpotomy or RCT between September 2010 and September 2012. Each incisor was classified into one of the following radiographic outcomes: N (incisor without pathologic change); Po (pathologic change present, follow-up recommended); Px (pathologic change present, extract...
January 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/28288780/neuroprotective-effects-of-gabaergic-phenols-correlated-with-their-pharmacological-and-antioxidant-properties
#5
Leticia Delgado-Marín, Mariela Sánchez-Borzone, Daniel A García
AIMS: Various investigations have demonstrated the protective capacity of general anesthetics as neuroprotective agents. The effects of propofol against ischemia are known to reside in its antioxidant properties and its GABAergic activity. Other aromatic alcohols have also been reported as able to protect neurons against oxidative damage. The aim of this work is to evaluate the potential neuroprotective effect of some phenols, structurally analogues of propofol, with proven GABAergic activity...
March 10, 2017: Life Sciences
https://www.readbyqxmd.com/read/28278638/phytochemical-study-and-biological-effects-of-the-essential-oil-of-fraxinus-dimorpha-coss-durieu-%C3%A2
#6
Soufiane M'sou, Mohamed Alifriqui, Abderrahmane Romane
The present study describes the phytochemical study, antioxidant and antimicrobial activities of Fraxinus dimorpha essential oil, obtained from the leaves collected in the High Atlas Mountains. Forty compounds representing 86.2% with (E)-nerolidol as a major constituent and 29 compounds corresponding to 80.3% with eugenol as main components were identified from Ait M'hamed and from Siti Fadma, respectively. The F. dimorpha essential oil presents IC50 using DPPH varying from 5.33 to 6.03 mg/mL and EC50 using FRAP varying from 0...
February 28, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28272477/chemosensitivity-of-mcf-7-cells-to-eugenol-release-of-cytochrome-c-and-lactate-dehydrogenase
#7
Rana Al Wafai, Warde El-Rabih, Meghri Katerji, Remi Safi, Marwan El Sabban, Omar El-Rifai, Julnar Usta
Phytochemicals have been extensively researched for their potential anticancer effects. In previous study, direct exposure of rat liver mitochondria to eugenol main ingredient of clove, uncoupled mitochondria and increased F0F1ATPase activity. In the present study, we further investigated the effects of eugenol on MCF-7 cells in culture. Eugenol demonstrated: a dose-dependent decrease in viability (MTT assay), and proliferation (real time cell analysis) of MCF-7 cells, (EC50: 0.9 mM); an increase in reactive oxygen species; a decrease in ATP level and mitochondrial membrane potential (MitoPT JC-1 assay); and a release of cytochrome-c and lactate dehydrogenase (Cytotoxicity Detection Kit (PLUS)) into culture media at eugenol concentration >EC50...
March 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28268019/a-novel-model-for-evaluating-the-flow-of-endodontic-materials-using-micro-computed-tomography
#8
Mario Tanomaru-Filho, Fernanda Ferrari Esteves Torres, Roberta Bosso-Martelo, Gisselle Moraima Chávez-Andrade, Idomeo Bonetti-Filho, Juliane Maria Guerreiro-Tanomaru
INTRODUCTION: Flow and filling ability are important properties of endodontic materials. The aim of this study was to propose a new technique for evaluating flow using micro-computed tomographic (μCT) imaging. METHODS: A glass plate was manufactured with a central cavity and 4 grooves extending out horizontally and vertically. The flow of MTA-Angelus (Angelus, Londrina, PR, Brazil), zinc oxide eugenol (ZOE), and Biodentine (BIO) (Septodont, Saint Maur des Fossés, France) was evaluated using International Standards Organization (ISO) 6876/2002 and a new technique as follows: 0...
March 3, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28258260/antimicrobial-efficacy-of-mixtures-of-nanosilver-and-zinc-oxide-eugenol-against-enterococcus-faecalis
#9
Roza Haghgoo, Motahareh Ahmadvand, Mohammad Nyakan, Mojtaba Jafari
AIM: This study aimed to assess the antimicrobial efficacy of 0, 0.5, 2, and 5 wt% nanosilver in conjunction with zinc oxide eugenol (ZOE) against Enterococcus faecalis. MATERIALS AND METHODS: Nanosilver in 0.5, 2, and 5 wt% concentrations was added to ZOE and the antibacterial activity of the mixtures on E. faecalis was assessed using disk diffusion method, and the results were reported as the diameter of the growth inhibition zone. RESULTS: The diameters of the growth inhibition zones around 0, 0...
March 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28254074/development-of-antibacterial-conjugates-using-sulfamethoxazole-with-monocyclic-terpenes-a-systematic-medicinal-chemistry-based-computational-approach
#10
Shasank S Swain, Sudhir K Paidesetty, Rabindra N Padhy
BACKGROUND AND OBJECTIVE: To develop 6 conjugate agents of the moribund antibiotic sulfamethoxazole (SMZ) joined to 6 individual monoterpenes, followed by protocols of medicinal chemistry as potent antibacterials, against multidrug resistant (MDR) human gruesome pathogenic bacteria. METHODS: Antibacterial activities of the proposed conjugates were ascertained by the 'prediction of activity spectra of substances' (PASS) program. Drug-likeness parameters and toxicity profiles of conjugates were standardized with the Lipinski rule of five, using cheminformatic tools, Molsoft, molinspiration, OSIRIS and ProTox...
March 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28242303/comparison-of-non-invasive-radiographic-measurements-of-soft-tissue-in-the-interdental-space-a-cadaver-study
#11
Kristian Kniha, Stephan Christian Möhlhenrich, Florian Peters, Tsanko Yovev, Manuel Räsch, Andreas Prescher, Frank Hölzle, Ali Modabber
When we use implants the aesthetic appearance of the patient is dependent to a large extent on identification of factors that influence the presence of interdental papillae. The aim of this study was to compare the accuracy of different non-invasive measurements to indicate the top of the interdental papilla on dental radiographs. The sample comprised six fresh, partly edentulous cadavers. The distance from the level of the interproximal bone next to the tip of the papilla was measured (n=330) on standard radiographic images...
February 24, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28223069/evaluation-of-antibacterial-potential-and-toxicity-of-plant-volatile-compounds-using-new-broth-microdilution-volatilization-method-and-modified-mtt-assay
#12
Marketa Houdkova, Johana Rondevaldova, Ivo Doskocil, Ladislav Kokoska
With aim to develop effective proof-of-concept approach which can be used in a development of new preparations for the inhalation therapy, we designed a new screening method for simple and rapid simultaneous determination of antibacterial potential of plant volatiles in the liquid and the vapour phase at different concentrations. In addition, EVA (ethylene vinyl acetate) capmat™ as vapour barrier cover was used as reliable modification of thiazolyl blue tetrazolium bromide (MTT) assay for cytotoxicity testing of volatiles on microtiter plates...
February 20, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28221905/efficacy-of-plant-derived-antimicrobials-in-controlling-enterohemorrhagic-escherichia-coli-virulence-in-vitro
#13
Sangeetha Ananda Baskaran, Anup Kollanoor-Johny, Meera Surendran Nair, Kumar Venkitanarayanan
Escherichia coli O157:H7 is a major foodborne pathogen that can cause serious human illness characterized by hemorrhagic diarrhea and kidney failure. The pathology of enterohemorrhagic E. coli O157:H7 (EHEC) infection is primarily mediated by verotoxins, which bind to the globotriaosylceramide receptor on host cells. Antibiotics are contraindicated for treating EHEC infection because they lead to increased verotoxin release, thereby increasing the risk of renal failure and death in patients. Thus, alternative strategies are needed for controlling EHEC infections in humans...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28213539/critical-concentration-of-lecithin-enhances-the-antimicrobial-activity-of-eugenol-against-escherichia-coli
#14
Haoshu Zhang, Edward G Dudley, P Michael Davidson, Federico Harte
Lecithin is a natural emulsifier used in a wide range of food and non-food applications to improve physical stability with no known bioactive effects. In this study, the effect of lecithin on the antimicrobial performance of a constant eugenol concentration was tested against three Escherichia coli strains (C600, 0.1229, and O157:H7 strain ATCC 700728). This was the first study focusing on lecithin at concentrations below those commonly used in foods to improve the stability of oil in water emulsions (≤ 10mg/100ml)...
February 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28213163/active-compound-diffusivity-of-particle-size-reduced-s-aromaticum-and-c-cassia-fused-starch-edible-films-and-the-shelf-life-of-mutton-capra-aegagrus-hircus-meat
#15
C Chandra Mohan, K Radha Krishnan, S Babuskin, K Sudharsan, Vajiha Aafrin, U Lalitha Priya, P Mariyajenita, K Harini, D Madhushalini, M Sukumar
In the present study, mathematical models were used to examine the effect of active compound diffusion from edible film (supplemented with S. aromaticum and C. cassia) on the microbial, physical and chemical quality of mutton stored at 4 and 10°C. Cinnamaldehyde and eugenol release from edible film into liquid was found to be 80% and 75% of the equilibrium concentration. Active compound release into meat was 42-51% for cinnamaldehyde and 38-48% for eugenol, in storage temperatures of 4-15°C. Developed mathematical models showed the diffusivity of cinnamaldehyde (0...
February 5, 2017: Meat Science
https://www.readbyqxmd.com/read/28213028/influence-of-application-sequence-and-timing-of-eugenol-and-lauric-arginate-lae-on-survival-of-spoilage-organisms
#16
Yudith Manrique, Monika Gibis, Herbert Schmidt, Jochen Weiss
The effectiveness of sequential applications of the antimicrobials eugenol and lauric arginate (LAE) was investigated against Staphylococcus carnosus, Listeria innocua, Escherichia coli K12, and Pseudomonas fluorescens. The antimicrobials were applied simultaneously at half of their minimum lethal concentrations (MLC) or sequentially at t = 0 h and t = 3, 4, 6 or 8 h. Bacterial survival was determined by direct plate counts. Survivals kinetic were fitted to a growth and mortality model to obtain characteristic parameters that described time-dependent changes from growth to mortality or vice versa...
June 2017: Food Microbiology
https://www.readbyqxmd.com/read/28179929/tooth-discoloration-resulting-from-a-nano-zinc-oxide-eugenol-sealer
#17
Mina Zarei, Maryam Javidi, Marzieh Jafari, Maryam Gharechahi, Pedram Javidi, Maryam Shayani Rad
INTRODUCTION: A desirable quality of any endodontic sealer is its ability to be tooth color friendly. Therefore the aim of the present study was to evaluate the tooth discoloration potential of a nano zinc oxide-eugenol (NZOE) sealer. METHODS AND MATERIALS: In order to evaluate tooth discoloration, the pulp chamber of 60 human maxillary central and lateral incisors were filled with one of the sealers, naming AH-26 (resin-based sealer), Pulpdent sealer (ZOE-based) and a NZOE experimental sealer...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28179927/subcutaneous-connective-tissue-reaction-to-a-new-nano-zinc-oxide-eugenol-sealer-in-rat-model
#18
Salma Omidi, Maryam Javidi, Mina Zarei, Siavash Mushakhian, Amirhossein Jafarian
INTRODUCTION: The aim of this animal study was to evaluate the histological response of the new nano zinc-oxide eugenol (NZOE) sealer in comparison with Pulp Canal Sealer (ZOE based) and AH-26 (epoxy resin sealer). METHODS AND MATERIALS: A total of 27 Wistar rats were used. Four polyethylene tubes were implanted in the back of each rat (three tubes containing the test materials and an empty tube as a control). Then, 9 animals were sacrificed at each interval of 15, 30 and 60 days, and the implants were removed with the surrounding tissues...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28179919/the-efficacy-of-passive-ultrasonic-activation-of-organic-solvents-on-dissolving-two-root-canal-sealers
#19
Letícia Trevisan, Isadora Razzera Huerta, Carina Michelon, Mariana De Carlo Bello, Rafael Pillar, Carlos Alexandre Souza Bier
INTRODUCTION: The aim of this in vitro study was to evaluate the dissolving efficacy of eucalyptol and orange oil solvents associated with passive ultrasonic activation (PUA) in zinc oxide-eugenol (ZOE) based and epoxy resin-based root canal sealers. METHODS AND MATERIALS: Seventy samples of each sealer were prepared and then randomized according to the solvent and the time of the ultrasonic activation (n=5). The mean amount of weight loss of sealers was calculated in percentages and was analyzed by using the Kruskal-Wallis and Bonferroni post-hoc tests...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28164397/four-main-active-ingredients-derived-from-a-traditional-chinese-medicine-guanxin-shutong-capsule-cause-cardioprotection-during-myocardial-ischemia-injury-calcium-overload-suppression
#20
Feng Liu, Zhuang-Zhuang Huang, Yu-Hong Sun, Ting Li, Dong-Hua Yang, Gang Xu, Ying-Ying Su, Tao Zhang
Guanxin Shutong capsule is a traditional Chinese medicine for the treatment of myocardial ischemia (MI). Previous studies have shown that the formula has four main active ingredients (FMAI), protocatechuic acid, cryptotanshinone, borneol, and eugenol. However, the mechanisms of action of these FMAI against MI injury are still not well known. The aim of the present study was to evaluate the protective effects of the FMAI on MI in vitro and in vivo. In vitro, rat neonatal cardiomyocytes were isolated, the cell viability and apoptosis rate were, respectively, measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method and fluorescence activating cell sorter, and the intracellular calcium concentration ([Ca(2+) ]i ) and CaM and CaMKII δ mRNA as well as protein levels were determined...
February 6, 2017: Phytotherapy Research: PTR
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