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Eugenol

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https://www.readbyqxmd.com/read/28937906/protein-activation-in-periapical-reaction-to-iodoform-containing-root-canal-sealer
#1
Nili Tickotsky, Moti Moskovitz
OBJECTIVES: An association between root canal sealers and periapical lesions in primary dentition has been suggested, yet the chemical-protein interactions that may be involved in it have not been studied. The present study explored root sealer components' effect on periapical tissue proteins using bioinformatics tools. STUDY DESIGN: For each chemical component of Endoflas F.S. root sealing material we identified the known and predicted target proteins, using STITCH (search tool for interactions of chemicals http://stitch...
September 22, 2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28933096/-in-vitro-and-in-vivo-recoveries-of-cutaneous-micro-dialysis-probe-of-paeonol-eugenol-and-piperine
#2
Chang Yang, Jie Bai, Shou-Ying Du, Ya-Hua Cui, Qin-Shuai Zhang, Jun-Ming Ma
To establish a method for detecting micro-dialysis recovery of paeonol, eugenol and piperine in Huoxue Zhitong patch, in order to provide the basis for further percutaneous pharmacokinetics studies. The concentrations of paeonol, eugenol and piperine in dialysates were determined by HPLC, and probe deliveries were calculated respectively. The effects of concentration and calibration approaches on the micro-dialysis probe deliveries of the three components were investigated, and their probe absorbability, in vitro and in vivo probe stability and repeatability were also studied...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28930241/chemical-composition-antimicrobial-and-antioxidant-activities-of-essential-oils-from-two-avicennia-schaueriana-stapf-leechm-ex-moldenke-acanthaceae-populations
#3
Kamilla N Machado, Telma M Kaneko, Maria Cláudia M Young, Cynthia Murakami, Inês Cordeiro, Paulo Roberto H Moreno
BACKGROUND: Avicennia schaueriana Stapf & Leechm. ex Moldenke (Acanthaceae) is a native species from the Brazilian mangroves presenting ecological and economic significance. This study compared the composition and the biological activities from the essential oils obtained from two A. schaueriana populations collected at Jureia-Itatins and Ilha do Cardoso. METHODS: Essential oils were obtained by conventional means, and their compositions were analyzed by GC-MS...
May 1, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28928533/control-of-aflatoxigenic-strains-by-cinnamomum-porrectum-essential-oil
#4
Oratai Sukcharoen, Pramote Sirirote, Dusanee Thanaboripat
Essential oil from the bark of Cinnamomum porrectum (Roxb.) Kosterm was obtained by hydrodistillation using a Clevenger-type system for 3 h and identified by gas chromatography-mass spectrometry. The compounds were safrole (93.9%), elemicine (4.3%) and methyl eugenol (1.7%). The effect of essential oil on mycelial growth, sporulation, and aflatoxin B1 production of Aspergillus parasiticus IMI 283883 and Aspergillus flavus IMI 242684 was evaluated using contact and vapor treatments. Aflatoxin B1 was determined using the Enzyme-linked immunosorbent assay...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28915591/eugenol-alleviated-breast-precancerous-lesions-through-her2-pi3k-akt-pathway-induced-cell-apoptosis-and-s-phase-arrest
#5
Min Ma, Yi Ma, Gui-Juan Zhang, Rui Liao, Xue-Feng Jiang, Xian-Xin Yan, Feng-Jie Bie, Xiao-Bo Li, Yan-Hong Lv
Eugenol can be separated from the oil extract of clove bud, and has many pharmacological functions such as anticancer and transdermal absorption. HER2/PI3K-AKT is a key signaling pathway in the development of breast cancer. In this study, 80 μM eugenol could significantly inhibit the proliferation of HER-2 positive MCF-10AT cells and the inhibition rate was up to 32.8%, but had no obvious inhibitory effect on MCF-7 and MCF-10A cells with HER2 weak expression. Eugenol also significantly induced human breast precancerous lesion MCF-10AT cell apoptosis and cell cycle S-phase arrest, but the biological effects nearly disappeared after HER2 over-expression through transfecting pcDNA3...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28914251/clinical-and-radiographic-comparison-of-platelet-rich-fibrin-and-mineral-trioxide-aggregate-as-pulpotomy-agents-in-primary-molars
#6
Surendra Patidar, Namita Kalra, Amit Khatri, Rishi Tyagi
AIM: This study aimed to evaluate and compare the Platelet-rich fibrin (PRF) and Mineral trioxide aggregate (MTA) as a pulpotomy agent in primary molars. MATERIAL AND METHODS: In this study, 50 primary molars from 50 healthy children aged 5-9 years requiring pulpotomy were randomly allocated into two groups. In PRF group, after coronal pulp removal and hemostasis, remaining pulp tissue was covered with PRF preparation. In the MTA group, the pulp stumps were covered with MTA (Pro Root MTA-Root Canal Repair Material, Dentsply International Inc...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28911620/composition-of-asarum-heterotropoides-var-mandshuricum-radix-oil-from-different-extraction-methods-and-activities-against-human-body-odor-producing-bacteria
#7
A S M Tanbirul Haque, Jin Nam Moon, P S Saravana, Adane Tilahun, Byung-Soo Chun
In this study, oils from Asarum heterotropoides were extracted by traditional solvent extraction and supercritical CO2 (SC-CO2) extraction methods and their antioxidant activities along with antimicrobial and inhibitory activities against five human body odor-producing bacteria (Staphylococcus epidermidis, Propionibacterium freudenreichii, Micrococcus luteus, Corynebacterium jeikeium, and Corynebacterium xerosis) were evaluated. The oil was found to contain 15 components, among which the most abundant component was methyl eugenol (37...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28885767/creating-peroxidase-oxidase-fusion-enzymes-as-toolbox-for-cascade-reactions
#8
Dana Colpa, Nikola Loncar, Mareike Schmidt, Marco Fraaije
In this work we prepared a set of bifunctional oxidase-peroxidases by fusing four distinct oxidases to a peroxidase. While such fusion enzymes have not been observed in nature, they could be expressed and purified with good yields. Characterization revealed that the artificial enzymes retained the capability to bind the two required cofactors and were catalytically active as oxidase and peroxidase. The peroxidase fusions of alditol oxidase and chitooligosaccharide oxidase could be used for selective detection of xylitol and cellobiose with a detection limit in the low µM range...
September 8, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28882947/expression-of-cyclooxygenase-2-nitric-oxide-synthase-2-and-heme-oxygenase-1-mrna-induced-by-bis-eugenol-in-raw264-7-cells-and-their-antioxidant-activity-determined-using-the-induction-period-method
#9
Yukio Murakami, Akifumi Kawata, Seiichiro Fujisawa
BACKGROUND/AIM: To clarify the mechanisms responsible for the anti-inflammatory/proinflammatory activities of eugenol-related compounds, we investigated the cytotoxicity and up-regulatory/down-refgulatory effects of the biphenols curcumin, bis-eugenol, magnolol and honokiol, and the monophenols eugenol and isoeugenol, on major regulators of cyclooxygenase-2 (Cox-2), nitric oxide synthase 2 (Nos2) and heme oxygenase-1 (HO-1) mRNA in RAW264.7 cells. MATERIALS AND METHODS: mRNA expression was investigated using real-time reverse transcriptase-polymerase chain reaction (RT-PCR), and the theoretical parameters were calculated using the DFT/B3LYP/6-31* method...
September 2017: In Vivo
https://www.readbyqxmd.com/read/28882342/the-analysis-of-aroma-flavor-compounds-in-green-tea-using-ice-concentration-linked-with-extractive-stirrer
#10
Abdullah H Alluhayb, Brian A Logue
Worldwide, green tea is one of the most popular beverages. It promotes blood circulation, liver function, and lowers the risk of cancer and cardiovascular diseases. This drink is characterized by the distinctive odors and flavors produced by its constituent compounds, with its value predicated on the amount and type of constituents extracted from the tea leaves during brewing. Ice concentration linked with extractive stirrer (ICECLES) is a novel sample preparation technique, especially applicable for the extraction of relatively polar compounds while retaining excellent extraction efficiencies for non-polar compounds...
August 25, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28881478/properties-of-bioroot-rcs-a-tricalcium-silicate-endodontic-sealer-modified-with-povidone-and-polycarboxylate
#11
F Siboni, P Taddei, F Zamparini, C Prati, M G Gandolfi
AIM: To evaluate the chemical and physical properties of a tricalcium silicate root canal sealer containing povidone and polycarboxylate (BioRoot RCS), a calcium silicate MTA-based sealer containing a salicylate resin (MTA Fillapex), a traditional eugenol-containing sealer (Pulp Canal Sealer) and an epoxy resin-based root canal sealer (AH Plus). METHODOLOGY: Calcium release, pH, setting time, water sorption, volume of open pores, volume of impervious portion, apparent porosity and weight loss were measured...
September 7, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28874840/uplc-q-tof-ms-based-metabonomic-studies-on-the-intervention-effects-of-aspirin-eugenol-ester-in-atherosclerosis-hamsters
#12
Ning Ma, Yajun Yang, Xiwang Liu, Xiaojun Kong, Shihong Li, Zhe Qin, Zenghua Jiao, Jianyong Li
Based on the pro-drug principle, aspirin and eugenol were used to synthesize aspirin eugenol ester (AEE) by esterification reaction. In present study, the anti-atherosclerosis effects of AEE were investigated in hamsters with the utilization of metabonomic approach based on UPLC-Q-TOF/MS. Biochemical parameters and histopathological injures in stomach, liver and aorta were evaluated. In atherosclerotic hamster, oral administration of AEE normalized biochemical profile such as reducing TG, TCH and LDL, and significantly reduced body weight gain, alleviated hepatic steatosis and improved pathological lesions in aorta...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28874207/evaluation-of-active-ingredients-and-larvicidal-activity-of-clove-and-cinnamon-essential-oils-against-anopheles-gambiae-sensu-lato
#13
Adelina Thomas, Humphrey D Mazigo, Alphaxard Manjurano, Domenica Morona, Eliningaya J Kweka
BACKGROUND: Mosquitoes are well-known vectors of many diseases including malaria and lymphatic filariasis. Uses of synthetic insecticides are associated with high toxicity, resistance, environmental pollution and limited alternative, effective synthetic insecticides. This study was undertaken to evaluate the larvicidal efficacy of clove and cinnamon essential oils against laboratory Anopheles gambiae (sensu stricto) and wild An. arabiensis larvae. METHODS: The standard WHO guideline for larvicides evaluation was used, and the GC-MS machine was used for active compounds percentage composition analysis and structures identification...
September 6, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28867749/nanoemulsion-a-suitable-nanodelivery-system-of-clove-oil-for-anesthetizing-nile-tilapia
#14
Kantaporn Kheawfu, Surachai Pikulkaew, Wasana Chaisri, Siriporn Okonogi
Clove oil ethanolic solution (CL-EtOH) have always been used for fish anesthesia. However, ethanol causes major side effect of fish hypersensivity. In this study, clove oil loaded nanoemulsion (CLN) was developed in order to enhance water miscibility of clove oil without using ethanol in the preparations. The obtained CLN was characterized in terms of droplet size, size distribution expressed as polydispersity index (PDI), and zeta potential. The anesthetic effect of CLN in comparison with CL-EtOH on Oreochromis niloticus (Nile tilapia) was investigated...
2017: Drug Discoveries & Therapeutics
https://www.readbyqxmd.com/read/28854647/chemical-degradation-of-tmr-multilure-dispensers-for-fruit-fly-detection-weathered-under-california-climatic-conditions
#15
COMPARATIVE STUDY
Roger I Vargas, Steven K Souder, Joseph G Morse, Elizabeth E Grafton-Cardwell, David R Haviland, John N Kabashima, Ben A Faber, Bruce Mackey, Eddie Nkomo, Peter J Cook, John D Stark
Degradation models for multilure fruit fly trap dispensers were analyzed to determine their potential for use in large California detection programs. Solid three-component male lure TMR (trimedlure [TML], methyl eugenol [ME], raspberry ketone [RK]) dispensers impregnated with DDVP (2, 2-dichlorovinyl dimethyl phosphate) insecticide placed inside Jackson traps were weathered during summer (8 wk) and winter (12 wk) in five citrus-growing areas. Additionally, TMR wafers without DDVP, but with an insecticidal strip, were compared to TMR dispensers with DDVP...
August 1, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28852637/an-in-vitro-study-to-evaluate-the-effect-of-eugenol-free-and-eugenol-containing-temporary-cements-on-the-bond-strength-of-resin-cement-and-considering-time-as-a-factor
#16
Lavanya Chiluka, Y Mahadev Shastry, Nidhi Gupta, K Mahendranadh Reddy, N B Prashanth, K Sravanthi
AIMS AND OBJECTIVES: The aim of this study was to assess the outcome of eugenol-free and eugenol-containing cements on the bond strength of resin cement. MATERIALS AND METHODS: Dentin was exposed in five groups of extracted teeth (20 specimens each). In Group 1, specimens were not given temporary cementation. In Groups 2 and 3, specimens were given temporary restoration fixed with eugenol-free temporary cement for 7 and 14 days, respectively. In Groups 4 and 5, specimens were given temporary restoration fixed with eugenol-containing temporary cement for 7 and 14 days, respectively...
July 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28852438/effect-of-eugenol-on-lithium-pilocarpine-model-of-epilepsy-behavioral-histological-and-molecular-changes
#17
Sara Joushi, Mahmoud Elahdadi Salmani
OBJECTIVES: Epilepsy establishment gives rise to biochemical and morphological changes in the hippocampus. Oxidative stress, morphological changes, and mossy fiber sprouting (MFS) in the hippocampus underpin the epilepsy establishment. Eugenol is the main component of the essential oil extracted from cloves with the potential to modulate neuronal excitability. Therefore, we investigated the effect of eugenol on convulsive behavior, oxidative stress, and histological changes of the hippocampus in lithium-pilocarpine model of epilepsy...
July 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28842540/critical-synergistic-concentration-of-lecithin-phospholipids-improve-the-antimicrobial-activity-of-eugenol-against-escherichia-coli
#18
Haoshu Zhang, Edward G Dudley, Federico Harte
In this study, the effect of individual lecithin phospholipids on the antimicrobial properties of eugenol against E. coli C600 was investigated. We tested five major phospholipids common in soy or egg lecithin (DPPC, DSPC, DPPE, DPPA and DPPS) and one synthetic cationic phospholipid (EPC 18:0). Among six phospholipids, DPPC, DSPC, DPPE, DPPA, and the cationic 18:0 EPC showed critical synergistic concentrations that significantly improve the inactivation effect of eugenol against E. coli after 30 min of exposure...
August 25, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28833280/acaricidal-activity-of-essential-oil-of-syzygium-aromaticum-hydrolate-and-eugenol-formulated-or-free-on-larvae-and-engorged-females-of-rhipicephalus-microplus
#19
F M Ferreira, C C Delmonte, T L P Novato, C M O Monteiro, E Daemon, F M P Vilela, M P H Amaral
The cattle tick, Rhipicephalus microplus (Canestrini, 1888) (Ixodida: Ixodidae), is the most important ectoparasite in cattle-breeding areas and is responsible for severe economic losses. Synthetic acaricides have been used to control this parasite. However, the need for safer products has stimulated the search for new acaricides, such as those to be obtained from medicinal plants. The essential oil of Syzygium aromaticum (clove) has many biological properties and shows great potential for use in veterinary applications...
August 18, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/28820497/anesthetic-agents-of-plant-origin-a-review-of-phytochemicals-with-anesthetic-activity
#20
REVIEW
Hironori Tsuchiya
The majority of currently used anesthetic agents are derived from or associated with natural products, especially plants, as evidenced by cocaine that was isolated from coca (Erythroxylum coca, Erythroxylaceae) and became a prototype of modern local anesthetics and by thymol and eugenol contained in thyme (Thymus vulgaris, Lamiaceae) and clove (Syzygium aromaticum, Myrtaceae), respectively, both of which are structurally and mechanistically similar to intravenous phenolic anesthetics. This paper reviews different classes of phytochemicals with the anesthetic activity and their characteristic molecular structures that could be lead compounds for anesthetics and anesthesia-related drugs...
August 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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