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Fernanda Ferrari Esteves Torres, Juliane Maria Guerreiro-Tanomaru, Roberta Bosso-Martelo, Gisselle Moraima Chavez-Andrade, Mario Tanomaru Filho
OBJECTIVE: To evaluate the absorption/fluid uptake, solubility and porosity of White mineral trioxide aggregate (MTA) Angelus, Biodentine (BIO), and zinc oxide-eugenol (ZOE). MATERIAL AND METHODS: Solubility was evaluated after immersion in distilled water for 7 and 30 days. Porosity was evaluated using digital inverted microscope, scanning electron microscope (SEM) and micro-computed tomography (micro-CT). For the fluid uptake test, specimens were immersed in Hank's balanced salt solution (HBSS) for 1, 7, 14 and 28 days...
2018: Journal of Applied Oral Science: Revista FOB
Huijun Yan, Sylvie Baudino, Jean-Claude Caissard, Florence Nicolè, Hao Zhang, Kaixue Tang, Shubin Li, Shugang Lu
The floral volatile compound eugenol is an important constituent in many aromatic plants, being a floral attractant for pollinators as well as having antimicrobial activity. Rose flowers emit eugenol and its derivatives. We recently reported a eugenol synthase gene (RcEGS1) (JQ522949) that was present in petals of R. chinensis cv. Old Blush. RcEGS1 has its highest expression levels in the petals compared to other tissues; it has higher transcript levels at the developmental blooming stage and lower levels at budding and senescence stages...
May 10, 2018: Plant Physiology and Biochemistry: PPB
Patrizia Monti, Gaia Rocchitta, Salvatore Marceddu, Maria A Dettori, Davide Fabbri, Samir Jaoua, Quirico Migheli, Giovanna Delogu, Pier A Serra
Interference rejection in amperometric biosensors can be more effective introducing some modifiers during electro-deposition of permselective film. Addition of β-cyclodextrin (βCD), a cyclic oligosaccharide composed of seven glucose units, to the ortho-phenylendiamine (oPD) monomer were already demonstrated to provide an enhancement in ascorbic acid (AA) rejection. Here we evaluated the improvement in permselectivity of poly-eugenol and poly-magnolol films electro-polymerized in presence of different amounts of βCD or eugenol-βCD inclusion complex for amperometric biosensor application...
August 15, 2018: Talanta
Swati Dalmia, Abhidnya Gaikwad, Roshan Samuel, Gayatri Aher, Meenal Gulve, Swapnil Kolhe
Objective: The aim of this in vitro study is to compare the antimicrobial efficacy of four different endodontic sealers against Enterococcus faecalis . Material and Method: Four different endodontic sealers, namely, resin based (AH Plus), zinc oxide-eugenol based (Tubliseal), calcium hydroxide based (Sealapex), and mineral trioxide aggregate (MTA Fillapex) based were tested for their antimicrobial efficacy against E. faecalis using agar diffusion method. Four wells were made by the removal of agar at equidistant points and filled with freshly mixed respective root canal sealers and were inoculated with E...
March 2018: Journal of International Society of Preventive & Community Dentistry
Ying Shao, Chunhua Wu, Tiantian Wu, Yuan Li, Shiguo Chen, Chunhong Yuan, Yaqin Hu
Eugenol is widely used in food industries where it encounters major concerns such as its poor solubility and stability. Herein, a novel eugenol-nanoemulsion was prepared by using ultrasonication as emulsification techniques, chitosan nanoparticle as carrier, and surfactant, as emulsifier. The results indicated that droplet size and encapsulation efficiency of the nanoemulsions was significantly affected by testing factors. The selected parameters for nanoemulsions were determined as chitosan-eugenol ratio of 1:1, Tween20 1 wt/v%, ultrasonic power 450 W and ultrasonic time 6 min...
August 1, 2018: Carbohydrate Polymers
Meirong Quan, Qi Zhi Liu, Zhi Long Liu
The essential oil of Stachys riederi var. japonica (Family: Lamiaceae) was extracted by hydrodistillation and determined by GC and GC-MS. A total of 40 components were identified, representing 96.01% of the total oil composition. The major compounds in the essential oil were acetanisole (15.43%), anisole (9.43%), 1,8-cineole (8.07%), geraniol (7.89%), eugenol (4.54%), caryophyllene oxide (4.47%), caryophyllene (4.21%) and linalool (4.07%). Five active constituents (acetanisole, anisole, 1,8-cineole, eugenol and geraniol) were identified by bioactivity-directed fractionation...
May 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Preet Bano Singh, Alix Young, Synnøve Lind, Marie Cathinka Leegaard, Alessandra Capuozzo, Valentina Parma
Despite the fact that human body odors can transfer anxiety-related signals, the impact of such signals in real-life situations is scant. In this study, the effects of anxiety chemosignals on the performance of dental students operating on simulation units, wearing t-shirts imbued with human sweat and masked with eugenol were tested. Twenty-four 4th year dental students (17F) donated their body odors in two sessions (Anxiety and Rest). Twenty-four normosmic, sex- and age-matched test subjects who were3rd year dental students performed three dental procedures while smelling masked anxiety body odors, masked rest body odors or masker alone...
May 15, 2018: Chemical Senses
Ajeet Kumar Singh, Sanjay Kumar, Manjula Vinayak
INTRODUCTION: Pain is an unpleasant sensation triggered by noxious stimulation. It is one of the most prevalent conditions, limiting productivity and diminishing quality of life. Non steroidal anti inflammatory drugs (NSAIDs) are widely used as pain relievers in present day practice as pain is mostly initiated due to inflammation. However, due to potentially serious side effects, long term use of these antihyperalgesic drugs raises concern. Therefore there is a demand to search novel medicines with least side effects...
May 16, 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
Vasileios Paraskeuas, Konstantinos Fegeros, Irida Palamidi, Christine Hunger, Konstantinos C Mountzouris
The effects of inclusion levels of a phytogenic feed additive (PFA), characterized by menthol anethol and eugenol, on broiler growth performance, nutrient digestibility, biochemical biomarkers and total antioxidant capacity (TAC) of plasma and meat, as well as on the relative expression of selected cytokines, were studied in a 42-d experiment. A total of 225 one-day-old male Cobb broiler chickens were assigned into 3 treatments, with 5 replicates of 15 chickens each. Chickens were fed maize-soybean meal basal diets following a 3 phase (i...
June 2017: Animal nutrition
Zahra Jamali, Vajiheh Alavi, Ebrahim Najafpour, Naser Asl Aminabadi, Sajjad Shirazi
OBJECTIVE: This study was conducted to compare the efficacy of 3Mixtatin (a combination of simvastatin and 3Mix antibiotic) with MTA and Formocresol for the pulpotomy of primary molars. STUDY DESIGN: 114 children aged 3-6 years old with 150 primary molars were randomly allocated to three groups. MTA, Formocresol or 3Mixtatin were used for Pulpotomies. Hard setting zinc oxide eugenol was used to cover these materials. The teeth were restored with amalgam. Blinded radiographic and clinical examinations were conducted at 6, 12 and 24 months after treatment for the presence of pain, tenderness to palpation and percussion, sinus tract, swelling, presence of internal or external root resorption, inter-radicular radiolucency, and periapical lesion...
May 15, 2018: Journal of Clinical Pediatric Dentistry
Zhenguang Li, Wenhong Hu, Yunhui Zhao, Lixia Ren, Xiaoyan Yuan
Integrated antibacterial and antifouling surfaces in favor of avoiding implant-related infections are necessarily required for biomaterials when they contact with the body fluid. In this work, an antibacterial and antifouling membrane was developed via cross-linking chitosan-g-eugenol and the zwitterionic copolymer poly(sulfobetaine methylacrylate-co-2-aminoethyl methacrylate) on the electrospun polycarbonate urethane substrate using genipin as a cross-linker. Antibacterial assays demonstrated that the prepared membranes had efficient antibacterial activity with 92...
April 27, 2018: Colloids and Surfaces. B, Biointerfaces
C W Pires, T L Lenzi, F Z M Soares, R O Rocha
AIM: This was to evaluate the influence of root canal filling pastes on microshear bond strength (µSBS) of an adhesive system to primary dentine. METHODS: Human (32) primary molars were randomly assigned into four experimental groups (n = 8): zinc oxide eugenol paste (ZOE); iodoform paste (Guedes-Pinto paste); calcium hydroxide paste thickened with zinc oxide; and no filling paste (control). Flat dentine surfaces were covered with a 1 mm-thick layer of the pastes for 15 min at 37 °C...
May 12, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
J Oh, M Harper, C H Lang, E H Wall, A N Hristov
This experiment was conducted to investigate the effects of phytonutrients, compared with monensin as a positive control, on productivity, milk fatty acids, fat mobilization, and blood cells in lactating dairy cows. Thirty-six Holstein cows were used in a 9-wk randomized complete block design study. Following a 2-wk covariate period, cows were blocked by days in milk, parity, and milk yield and randomly assigned to 1 of 3 treatments (12 cows/treatment): 450 mg/cow per day of monensin (MO), 250 mg/cow per day of capsicum plus 450 mg/cow per day of MO (MOCAP), and 1,000 mg/cow per day of a mixture of cinnamaldehyde, eugenol, and capsicum (CEC)...
May 9, 2018: Journal of Dairy Science
Jose E J Akhil, Babaji Prashant, K K Shashibushan
OBJECTIVES: Successful pulpectomy in primary teeth depends on quality of obturation. It can be evaluated using digital intra-oral receptor (D.I.O.R) and cone beam computed tomography (C.B.C.T). The purposes of this study were to compare 3 different obturation techniques such as lentulospiral, insulin syringe, and endodontic plugger in primary incisors and to evaluate its quality of obturation using D.I.O.R and C.B.C.T technique. MATERIALS AND METHODS: Thirty-three extracted primary incisors were biomechanically prepared and obturated with zinc oxide eugenol cement by 3 different obturation techniques...
May 10, 2018: Clinical Oral Investigations
G Bandeira Junior, F J Sutili, L T Gressler, V L Ely, B P Silveira, C Tasca, M Reghelin, L B Matter, A P C Vargas, B Baldisserotto
AIMS: This study investigated the antibacterial activity of five phytochemicals (carvacrol, citral, eugenol, linalool, and thymol) alone or in combination with florfenicol or oxytetracycline against bacteria isolated from silver catfish (Rhamdia quelen). We also analyzed the potential of these compounds to inhibit biofilm formation and hemolysis caused by the bacteria. METHODS AND RESULTS: Bacteria were tested with antimicrobials to calculate the multiple antibiotic resistance (MAR)...
May 9, 2018: Journal of Applied Microbiology
Grant T McQuate, Jane E Royer, Charmaine D Sylva
Bactrocera latifrons (Hendel) (Diptera: Tephritidae) is a pest fruit fly species native to Oriental Asia which has invaded and established in Hawaii and Tanzania and has been recovered in detection trapping in California. It is largely non-responsive to the male lures cuelure and methyl eugenol. Alpha-ionol + cade oil is a moderately effective male B. latifrons attractant, but is not as attractive as cuelure or methyl eugenol are to other fruit fly species. An improved attractant is therefore desired. With the recent success in finding other non-responsive fruit fly species attracted to isoeugenol, methyl-isoeugenol, or dihydroeugenol in Australia and other countries, we wanted to assess whether B...
May 1, 2018: Insects
Satish Kanhar, Atish Kumar Sahoo, Ajay Kumar Mahapatra
The purpose of this study was to evaluate ameliorative effects of Homalium nepalense Benth. (Flacourtiaceae) on CCl4 -induced hepatocellular injury in rats. Oxygen-radical absorbance-capacity (ORAC) and cell-based-antioxidant-protection-in-erythrocytes (CAP-e) were performed and found that the ethyl acetate fractions of bark (HNEB) and leaf (HNEL) showed a remarkable degree of antioxidant activities in a dose dependent manner. Antioxidant potential HNEB was higher than HNEL and was comparable with trolox. HNEB and HNEL at 300 and 400 mg/kg showed significant hepatoprotective activities against CCl4 -induced hepatotoxicity as evidenced by restoration of SGOT, SGPT, ALP, TB and TP level...
April 23, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
D Staseviciene, A Chomiciene, L Malinauskiene, J Grigaitiene
Sweet bay or Laurus nobilis is a typical plant in Mediterranean region and is used as an ornamental or herbal plant. Laurel leaf and fruit oil is widely use in cosmetic products and in folk medicine because of its anti-inflammatory, analgesic, antioxidant and antibacterial features (1, 2). Over 20 constituents such as sesquiterpene lactones (SLs), linalool, terpinelol, eugenol and others are found in laurel fruit oil (3, 4). The positive patch test result to SLs can be a possible marker to fragrance allergy (5)...
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Feng Liu, Xia DU, Pei-Rong Liu, Yu-Hong Sun, Yan-Min Zhang
Guanxinshutong capsule (GXSTC) is an effective and safe traditional Chinese medicine used in the treatment of cardiovascular diseases (CVDs) for many years. However, the targets of this herbal formula and the underlying molecular mechanisms of action involved in the treatment of CVDs are still unclear. In the present study, we used a systems pharmacology approach to identify the active ingredients of GXSTC and their corresponding targets in the calcium signaling pathway with respect to the treatment of CVDs...
April 2018: Chinese Journal of Natural Medicines
Taciane Maíra Magalhães Hipólito, Guilherme Tadeu Lemos Bastos, Thúlio Wliandon Lemos Barbosa, Thiago Belarmino de Souza, Luiz Felipe Leomil Coelho, Amanda Latércia Tranches Dias, Ihosvany Camps Rodríguez, Marcelo Henrique Dos Santos, Danielle Ferreira Dias, Lucas Lopardi Franco, Diogo Teixeira Carvalho
Seventeen new synthetic derivatives of eugenol (6, 8-15 and 8'-15') were planned following literature reports on antifungal activities of nitroeugenol and eugenol glucoside. The anti-Candida activity of these compounds was investigated by in vitro assay and the cytotoxicity evaluation was performed with the most active compounds. The peracetylated glucosides presented better biological results than their hydroxylated analogues. The glucoside 11, a 4-nitrobenzamide, showed the best potency (MIC50 range 11.0-151...
April 25, 2018: Chemical Biology & Drug Design
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