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https://www.readbyqxmd.com/read/28431540/prevention-of-advanced-glycation-end-products-formation-in-diabetic-rats-through-beta-cell-modulation-by-aegle-marmelos
#1
Rahman M Hafizur, Shahrukh Momin, Noor Fatima
BACKGROUND: Although the anti-diabetic activity of Aegle marmelos (AM) is known, however, its anti-glycation activity is not reported yet. In this study, we have investigated its anti-glycation activity under in vitro and in vivo conditions and determined possible mechanism(s) in streptozotocin-induced diabetic rats. METHODS: Effective dose of AM (400 mg/kg) was administrated orally to diabetic rats for 42 days. Thereafter, blood glucose, serum insulin, HbA1c, antioxidant status, and advanced glycation end-products (AGEs) were measured...
April 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28431295/clove-and-rosemary-essential-oils-and-encapsuled-active-principles-eugenol-thymol-and-vanillin-blend-on-meat-quality-of-feedlot-finished-heifers
#2
Jéssica de Oliveira Monteschio, Kennyson Alves de Souza, Ana Carolina Pelaes Vital, Ana Guerrero, Maribel Velandia Valero, Emília Maria Barbosa Carvalho Kempinski, Vinícius Cunha Barcelos, Karina Favoreto Nascimento, Ivanor Nunes do Prado
Forty Nellore heifers were fed (73days) with different diets: with or without essential oils (clove and/or rosemary essential oil) and/or active principle blend (eugenol, thymol and vanillin). The pH, fat thickness, marbling, muscle area and water losses (thawing and drip) were evaluated 24h post mortem on the Longissimus thoracis, and the effects of aging (14days) was evaluated on the meat cooking losses, color, texture and lipid oxidation. Antioxidant activity was also evaluated. Treatments had no effect (P>0...
April 5, 2017: Meat Science
https://www.readbyqxmd.com/read/28422054/growth-inhibition-of-sulfate-reducing-bacteria-in-produced-water-from-the-petroleum-industry-using-essential-oils
#3
Pamella Macedo de Souza, Fátima Regina de Vasconcelos Goulart, Joana Montezano Marques, Humberto Ribeiro Bizzo, Arie Fitzgerald Blank, Claudia Groposo, Maíra Paula de Sousa, Vanessa Vólaro, Celuta Sales Alviano, Daniela Sales Alviano Moreno, Lucy Seldin
Strategies for the control of sulfate-reducing bacteria (SRB) in the oil industry involve the use of high concentrations of biocides, but these may induce bacterial resistance and/or be harmful to public health and the environment. Essential oils (EO) produced by plants inhibit the growth of different microorganisms and are a possible alternative for controlling SRB. We aimed to characterize the bacterial community of produced water obtained from a Brazilian petroleum facility using molecular methods, as well as to evaluate the antimicrobial activity of EO from different plants and their major components against Desulfovibrio alaskensis NCIMB 13491 and against SRB growth directly in the produced water...
April 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28415462/microencapsulation-of-eugenol-molecules-by-%C3%AE-cyclodextrine-as-a-thermal-protection-method-of-antibacterial-action
#4
R Piletti, A M Bugiereck, A T Pereira, E Gussati, J Dal Magro, J M M Mello, F Dalcanton, R Z Ternus, C Soares, H G Riella, M A Fiori
Eugenol is natural oil that has excellent antibacterial properties but cannot be used to fabricate many products that require thermal processing. One possible alternative to the use of the eugenol molecules in high-temperature processes is the encapsulation of these molecules in a structure that is not toxic and is resistant to thermal treatment. This work investigated the encapsulation process of eugenol molecules in β-cyclodextrine and the antibacterial properties of eugenol-β-cyclodextrine (the eugenol-βCD complex) against Escherichia coli and Staphylococcus aureus...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28413973/docking-related-survey-on-natural-product-based-new-monoamine-oxidase-inhibitors-and-their-therapeutic-potential
#5
Priyanka Dhiman, Neelam Malik, Anurag Khatkar
This is an exciting period for research on monoamine oxidase and its effects on central nervous system. As the current hitting-one-target therapeutic strategy has become quite inefficient for the treatment of various neurological disorders. The objective of this review is to identify and critically discuss the computational development of multi-target natural and related ligand-MAO protein docking approaches in the study of monoamine oxidase (MAO) enzymes. Computational development of the new compounds form natural and related synthetic origin, active as MAO inhibitors (MAOIs) were discussed in some detail...
April 14, 2017: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/28407719/anti-inflammatory-activity-of-clove-eugenia-caryophyllata-essential-oil-in-human-dermal-fibroblasts
#6
Xuesheng Han, Tory L Parker
CONTEXT: Clove (Eugenia caryophyllata Thunb. [Myrtaceae]) essential oil (CEO) has been shown to possess antimicrobial, antifungal, antiviral, antioxidant, anti-inflammatory and anticancer properties. However, few studies have focused on its topical use. OBJECTIVE: We investigated the biological activity of a commercially available CEO in a human skin disease model. MATERIALS AND METHODS: We evaluated the effect of CEO on 17 protein biomarkers that play critical roles in inflammation and tissue remodelling in a validated human dermal fibroblast system, which was designed to model chronic inflammation and fibrosis...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28399279/the-botanical-monoterpenes-linalool-and-eugenol-flush-out-nymphs-of-triatoma-infestans-hemiptera-reduviidae
#7
A N Moretti, E A Seccacini, E N Zerba, D Canale, R A Alzogaray
Monoterpenes are the main components of essential oils. Some members of this chemical family present insecticidal activity. Triatoma infestans (Klug) is the main vector of Chagas disease in Argentina, Bolivia, Paraguay, and Perú. The objective of this work was to evaluate the effect of six monoterpenes (1,8-cineole, eugenol, linalool, menthol, α-terpineol, and thymol) on the locomotor and flushing out activity of T. infestans. A video tracking technique was used to evaluate the locomotor activity of nymphs exposed to different concentrations of these chemicals applied as films on filter paper...
March 29, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28392905/cinnamaldehyde-and-eugenol-change-the-expression-folds-of-akt1-and-dkc1-genes-and-decrease-the-telomere-length-of-human-adipose-derived-stem-cells-hascs-an-experimental-and-in-silico-study
#8
Abdorrahim Absalan, Seyed Alireza Mesbah-Namin, Taki Tiraihi, Taher Taheri
OBJECTIVES: To investigate the effect of cinnamaldehyde and eugenol on the telomere-dependent senescence of stem cells. In addition, to search the probable targets of mentioned phytochemicals between human telomere interacting proteins (TIPs) using in silico studies. MATERIALS AND METHODS: Human adipose derived stem cells (hASCs) were studied under treatments with 2.5 µM/ml cinnamaldehyde, 0.1 µg/ml eugenol, 0.01% DMSO or any additive. The expression of TERT, AKT1 and DKC1 genes and the telomere length were assessed over 48-hr treatment...
March 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28390465/antibiofilm-activity-of-five-different-endodontic-filling-materials-used-in-primary-teeth-using-confocal-laser-scanning-microscopy
#9
Katerine Jahnecke Pilownic, Ceci Nunes Carvalho, Ana Regina Romano, Renata Dornelles Morgental, Ya Shen, Markus Haapasalo, Fernanda Geraldo Pappen
PURPOSE: The purpose of this study was to evaluate the effect of five endodontic materials for primary teeth on in vitro mixed-species biofilms. METHODS: Zinc oxide eugenol (ZOE) cement, Vitapex, Calen paste thickened with zinc oxide (ZO), pure calcium hydroxide (Ca(OH)2) paste, and iodoform were evaluated. Sterile water was used as a control. Mixed-species biofilm was incubated in anaerobic conditions for 21 days. The biofilm specimens were placed in contact with the endodontic materials for periods of seven and 30 days...
March 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/28390451/a-comparative-volumetric-evaluation-of-four-obturating-techniques-in-primary-teeth-using-cone-beam-computed-tomography
#10
Aparna Singh, Nidhi Gupta, Nidhi Agarwal, Dipanshu Kumar, Ashish Anand
PURPOSE: To compare the volume of root canals of primary teeth filled by four different obturating techniques: (1) lentulospiral (LS); (2) insulin syringe (IS); (3) endodontic pressure syringe (EPS); and (4) the NaviTip system (NS) using cone beam computed tomography (CBCT). METHODS: 76 root canals of primary posterior teeth were selected and divided into four groups, according to the obturation technique. Biomechanical preparation of each root canal was completed with a number 30 K-file, and the volumes of the canals were then measured using CBCT...
March 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/28380280/alcohol-acyl-transferase-1-links-two-distinct-volatile-pathways-that-produce-esters-and-phenylpropenes-in-apple-fruit
#11
Yar-Khing Yauk, Edwige J F Souleyre, Adam J Matich, Xiuyin Chen, Mindy Y Wang, Blue Plunkett, Andrew P Dare, Richard V Espley, Sumathi Tomes, David Chagné, Ross G Atkinson
Fruit accumulate a diverse set of volatiles including esters and phenylpropenes. Volatile esters are synthesised via fatty acid degradation or from amino acid precursors with the final step being catalysed by alcohol acyl transferases (AATs). Phenylpropenes are produced as a side branch of the general phenylpropanoid pathway. Major QTLs on apple (Malus x domestica) LG2 for production of the phenylpropene estragole and volatile esters (including 2-methylbutyl acetate and hexyl acetate) both co-located with the MdAAT1 gene...
April 5, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28374545/identification-of-walnut-husk-juglans-regia-l-volatiles-and-the-behavioral-response-of-the-invasive-walnut-husk-fly-rhagoletis-completa-cresson
#12
Landry Sarles, Antoine Boullis, Bérénice Fassotte, Georges Lognay, Agnès Verhaeghe, Frédéric Francis, François J Verheggen
BACKGROUND: Several European countries are important walnut (Juglans regia L.) producers. However, these countries must contend with the recent introduction of the Walnut Husk Fly, Rhagoletis completa Cresson (Diptera, Tephritidae), which is causing severe economic losses, especially in organic production. Because most Tephritid fruit flies use kairomones in their search for host plants, we hypothesize that this highly specialist species orients toward the volatile blend released by walnut husks...
April 3, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28368215/effects-of-lipid-formulations-on-clove-extract-spray-dried-powders-comparison-of-physicochemical-properties-storage-stability-and-in-vitro-intestinal-permeation
#13
Diego F Cortes-Rojas, Claudia R F Souza, Mong-Jen Chen, Guenther Hochhaus, Wanderley P Oliveira
Clove is an aromatic plant spice with potent antioxidant and anti-inflammatory activity. Eugenol is the main compound which contributes to such medicinal and nutritional benefits. To date, the formulation of unstable, volatile, and poorly water soluble compounds remains a challenging task. Lipid formulations can be used to improve physicochemical and biopharmaceutical properties of poorly soluble compounds. The aim of the present study is to investigate the effects of lipids such as Gelucire and Compritol on physicochemical properties, stability and in vitro intestinal permeation of spray dried powdered formulations loaded with clove's bioactive compounds...
April 3, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28366608/the-effect-of-drought-stress-on-the-expression-of-key-genes-involved-in-the-biosynthesis-of-phenylpropanoids-and-essential-oil-components-in-basil-ocimum-basilicum-l
#14
Babak Abdollahi Mandoulakani, Elham Eyvazpour, Morteza Ghadimzadeh
Basil (Ocimum basilicum L.), a medicinal plant of the Lamiaceae family, is used in traditional medicine; its essential oil is a rich source of phenylpropanoids. Methylchavicol and methyleugenol are the most important constituents of basil essential oil. Drought stress is proposed to enhance the essential oil composition and expression levels of the genes involved in its biosynthesis. In the current investigation, an experiment based on a completely randomized design (CRD) with three replications was conducted in the greenhouse to study the effect of drought stress on the expression level of four genes involved in the phenylpropanoid biosynthesis pathway in O...
March 30, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28365674/neuroprotective-effects-of-eugenol-against-aluminiuminduced-toxicity-in-the-rat-brain
#15
Mahmoud M Said, Marwa M Abd Rabo
Aluminium (Al) is a neurotoxic metal that contributes to the progression of several neurodegenerative diseases. The aim of the present study was to evaluate the protective effect of dietary eugenol supplementation against aluminium (Al)- induced cerebral damage in rats. Male Wistar rats were divided into four groups: normal controls, rats fed a diet containing 6,000 μg g-1 eugenol, rats intoxicated daily with aluminium chloride (84 mg kg-1 body weight) p. o. and fed either a basal diet or a eugenol-containing diet...
March 1, 2017: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28358602/in-vitro-incorporation-of-radioiodinated-eugenol-on-adenocarcinoma-cell-lines-caco2-mcf7-and-pc3
#16
Emine Dervis, Ayfer Yurt Kilcar, Emin Ilker Medine, Volkan Tekin, Buse Cetkin, Emre Uygur, Fazilet Zumrut Biber Muftuler
Recently, the synthesis of radiolabeled plant origin compounds has been increased due to their high uptake on some cancer cell lines. Eugenol (EUG), a phenolic natural compound in the essential oils of different spices such as Syzygium aromaticum (clove), Pimenta racemosa (bay leaves), and Cinnamomum verum (cinnamon leaf), has been exploited for various medicinal applications. EUG has antiviral, antioxidant, and anti-inflammatory functions and several anticancer properties. The objective of this article is to synthesize radioiodinated ((131)I) EUG and investigate its effect on Caco2, MCF7, and PC3 adenocarcinoma cell lines...
April 2017: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/28357646/the-usefulness-of-non-toxic-plant-metabolites-in-the-control-of-bacterial-proliferation
#17
Sergio Gutiérrez, Alfredo Morán, Honorina Martínez-Blanco, Miguel A Ferrero, Leandro B Rodríguez-Aparicio
The effect of generally recognised as safe (GRAS) plant metabolites in regulating the growth of human pathogenic and probiotic bacteria and in the formation of biofilm was investigated. Thymol, carvacrol and eugenol showed the strongest antibacterial action against both pathogenic and probiotic microorganisms, at a subinhibitory concentration (SIC) of ≤50 μg ml(-1). Genistein, hydroquinone, p-hydroxybenzoic acid and resveratrol also showed antibacterial effects but at a wide concentration range (SIC = 50-1000 μg ml(-1))...
March 29, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28347181/verification-of-key-odorants-in-rose-oil-by-gas-chromatography-olfactometry-aroma-extract-dilution-analysis-odour-activity-value-and-aroma-recombination
#18
Zuobing Xiao, Jing Li, Yunwei Niu, Qiang Liu, Junhua Liu
Rose oil is much too expensive but very popular. It's well known that the flower oil's aroma profile hasn't been intensively investigated. In order to verify the aroma profile of rose oil, the synthetic blend of odorants was prepared and then compared with the original rose oil using electronic nose analysis (ENA) combined with quantitative descriptive analysis (QDA). The odorants from rose oils were screened out by Gas Chromatography-Olfactometry/aroma extract dilution analysis (GC-O/AEDA) combined with odour activity value (OAV)...
March 28, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28346030/antimicrobial-activity-of-eugenol-and-essential-oils-containing-eugenol-a-mechanistic-viewpoint
#19
Anna Marchese, Ramona Barbieri, Erika Coppo, Ilkay Erdogan Orhan, Maria Daglia, Seyed Fazel Nabavi, Morteza Izadi, Mohammad Abdollahi, Seyed Mohammad Nabavi, Marjan Ajami
Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families. It is one of the major constituents of clove (Syzygium aromaticum (L.) Merr. & L.M. Perry, Myrtaceae) oil and is largely used in both foods and cosmetics as a flavoring agent. A large body of recent scientific evidence supports claims from traditional medicine that eugenol exerts beneficial effects on human health. These effects are mainly associated with antioxidant and anti-inflammatory activities...
March 27, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28342670/chemical-composition-and-acaricide-activity-of-an-essential-oil-from-a-rare-chemotype-of-cinnamomum-verum-presl-on-rhipicephalus-microplus-acari-ixodidae
#20
Ildenice Nogueira Monteiro, Odair Dos Santos Monteiro, Lívio Martins Costa-Junior, Aldilene da Silva Lima, Eloisa Helena de Aguiar Andrade, José Guilherme Soares Maia, Victor Elias Mouchrek Filho
The Essential Oils (EOs) from the leaves of species Cinnamomum verum J. Presl are used in the pharmaceutical industry for their numerous biological activities. Currently, the main compound of C. verum EO is eugenol which has acaricidal activity; however, a rare chemotype with benzyl benzoate as the main component can be found. Benzyl benzoate is recognized as an acaricide; however, studies of the C. verum EOs benzyl benzoate chemotype on Rhipicephalus microplus were not reported. The aim of this study was to evaluate the acaricide activity of an EO from a rare chemotype of C...
March 18, 2017: Veterinary Parasitology
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