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https://www.readbyqxmd.com/read/28884432/plasma-enterolactone-and-risk-of-prostate-cancer-in-middle-aged-swedish-men
#1
Peter Wallström, Isabel Drake, Emily Sonestedt, Bo Gullberg, Anders Bjartell, Håkan Olsson, Herman Adlercreutz, Matti J Tikkanen, Elisabet Wirfält
PURPOSE: Enterolactone (ENL) is formed in the human gut after consumption of lignans, has estrogenic properties, and has been associated with risk of prostate cancer. We examined the association between plasma ENL levels and prostate cancer in a nested case-control study within the population-based Malmö Diet and Cancer cohort. We also examined the association between plasma ENL and dietary and lifestyle factors. METHODS: The study population consisted of 1010 cases occurring during a mean follow-up of 14...
September 7, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28865736/association-between-inflammatory-diet-pattern-and-risk-of-colorectal-carcinoma-subtypes-classified-by-immune-responses-to-tumor
#2
Li Liu, Reiko Nishihara, Zhi Rong Qian, Fred K Tabung, Daniel Nevo, Xuehong Zhang, Mingyang Song, Yin Cao, Kosuke Mima, Yohei Masugi, Yan Shi, Annacarolina da Silva, Tyler Twombly, Mancang Gu, Wanwan Li, Tsuyoshi Hamada, Keisuke Kosumi, Kentaro Inamura, Jonathan A Nowak, David A Drew, Paul Lochhead, Katsuhiko Nosho, Kana Wu, Molin Wang, Wendy S Garrett, Andrew T Chan, Charles S Fuchs, Edward L Giovannucci, Shuji Ogino
BACKGROUND & AIMS: Dietary patterns affect systemic and local intestinal inflammation, which have been linked to colorectal carcinogenesis. Chronic inflammation can interfere with the adaptive immune response. We investigated whether the association of a diet that promotes intestinal inflammation with risk of colorectal carcinoma was stronger for tumors with lower lymphocytic reactions than tumors with higher lymphocytic reactions. METHODS: We collected data from the molecular pathological epidemiology databases of 2 prospective cohort studies: the Nurses' Health Study (since 1976) and the Health Professional Follow-up Study (since 1986)...
August 30, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28853910/coffee-consumption-and-disease-correlations
#3
Buşra Basar Gokcen, Nevin Sanlİer
Coffee is one of the most widely consumed beverages in the world. It has primarily consumed due to its stimulant effect and unique taste since the ancient times. Afterwards, its consumption has been historically associated with a lower risk of some diseases such as type 2 diabetes mellitus, obesity, cardiovascular disease and some type of cancer and thus it has also consumed due to health benefits. It contains many bioactive compounds such as caffeine, chlorogenic acids and diterpenoid alcohols which have so far been associated with many potential health benefits...
August 30, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28853102/an-up-to-date-meta-analysis-of-coffee-consumption-and-risk-of-prostate-cancer
#4
Jiadong Xia, Jie Chen, Jian-Xin Xue, Jie Yang, Zeng-Jun Wang
PURPOSE: Results of the association between coffee consumption (CC) and the risk of prostate cancer (PC) are still controversy. Based on published relevant studies, we conducted an up-to-date meta-analysis to investigatethis issue. MATERIALS AND METHODS: The protocol used in this article is in accordance with the PRISMA checklist. Eligible studies were screened and retrieved by using PUBMED and EMBASE as well as manual review of references up to July 2016. We calculated the pooled relative risk (RR) with 95% confidence interval (CI) with random effect models...
August 29, 2017: Urology Journal
https://www.readbyqxmd.com/read/28846640/coffee-consumption-and-risk-of-biliary-tract-cancers-and-liver-cancer-a-dose-response-meta-analysis-of-prospective-cohort-studies
#5
Justyna Godos, Agnieszka Micek, Marina Marranzano, Federico Salomone, Daniele Del Rio, Sumantra Ray
BACKGROUND: A meta-analysis was conducted to summarize the evidence from prospective cohort and case-control studies regarding the association between coffee intake and biliary tract cancer (BTC) and liver cancer risk. METHODS: Eligible studies were identified by searches of PubMed and EMBASE databases from the earliest available online indexing year to March 2017. The dose-response relationship was assessed by a restricted cubic spline model and multivariate random-effect meta-regression...
August 28, 2017: Nutrients
https://www.readbyqxmd.com/read/28832574/hot-infusions-and-risk-of-colorectal-cancer-in-uruguay-a-case-control-study
#6
A L Ronco, E De Stefani, E Lasalvia-Galante, B Mendoza, A Vazquez, G Sanchez
BACKGROUND/OBJECTIVES: The evidence of possible roles for the most common hot infusions intake (tea and coffee) in the risk of colorectal cancer (CRC) needs additional data. Regarding 'mate' intake (infusion of Ilex paraguariensis herb), a previous multi-site study reported lack of association for its highest intake on CRC risk. The present study was conducted to better understand the associations between the intake of this and other infusions and CRC risk. SUBJECTS/METHODS: Patients (611 CRC incident cases and 2394 controls, all belonging to public hospitals) were interviewed through a questionnaire, including socio-demographic, reproductive and lifestyle variables, and a food-frequency questionnaire of 64 items, analyzing tea, 'mate' and coffee intake (consumer status, daily intake, age at start and at quit)...
August 23, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28826374/coffee-caffeine-and-health-outcomes-an-umbrella-review
#7
Giuseppe Grosso, Justyna Godos, Fabio Galvano, Edward L Giovannucci
To evaluate the associations between coffee and caffeine consumption and various health outcomes, we performed an umbrella review of the evidence from meta-analyses of observational studies and randomized controlled trials (RCTs). Of the 59 unique outcomes examined in the selected 112 meta-analyses of observational studies, coffee was associated with a probable decreased risk of breast, colorectal, colon, endometrial, and prostate cancers; cardiovascular disease and mortality; Parkinson's disease; and type-2 diabetes...
August 21, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28809372/coffee-is-protective-against-oral-and-pharyngeal-cancer-a-systematic-review-and-meta-analysis
#8
J Miranda, L Monteiro, R Albuquerque, J-J Pacheco, Z Khan, J Lopez-Lopez, S Warnakulasuryia
OBJECTIVES: Coffee is one of the most popular and consumable drinks worldwide. However, there are conflicting results on the influence of this drink in oral and pharyngeal cancer risk. To clarify this, we aimed to systemically review and carry out a meta-analysis of the relevant literature on the association between coffee and oral and pharyngeal cancer. STUDY DESIGN: We carried out an electronic search of publications up to August 2016 from PubMed, National Library of Medicines Medline, Embase, Science Direct and the Cochrane Central Register...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28804505/an-etiologic-prediction-model-incorporating-biomarkers-to-predict-the-bladder-cancer-risk-associated-with-occupational-exposure-to-aromatic-amines-a-pilot-study
#9
Giuseppe Mastrangelo, Angela Carta, Cecilia Arici, Sofia Pavanello, Stefano Porru
BACKGROUND: No etiological prediction model incorporating biomarkers is available to predict bladder cancer risk associated with occupational exposure to aromatic amines. METHODS: Cases were 199 bladder cancer patients. Clinical, laboratory and genetic data were predictors in logistic regression models (full and short) in which the dependent variable was 1 for 15 patients with aromatic amines related bladder cancer and 0 otherwise. The receiver operating characteristics approach was adopted; the area under the curve was used to evaluate discriminatory ability of models...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28768299/a-prospective-investigation-of-coffee-drinking-and-bladder-cancer-incidence-in-the-united-states
#10
Erikka Loftfield, Neal D Freedman, Maki Inoue-Choi, Barry I Graubard, Rashmi Sinha
BACKGROUND: In 1991, coffee was classified as a group 2B carcinogen, possibly carcinogenic to humans, based on limited epidemiologic evidence of a positive association with bladder cancer. In 2016, the International Agency for Research on Cancer downgraded this classification due to lack of evidence from prospective studies particularly for never smokers. METHODS: Baseline coffee drinking was assessed with a food frequency questionnaire in the NIH-AARP prospective cohort study...
September 2017: Epidemiology
https://www.readbyqxmd.com/read/28765341/coffee-and-green-tea-consumption-and-subsequent-risk-of-malignant-lymphoma-and-multiple-myeloma-in-japan-the-japan-public-health-center-based-prospective-study
#11
Tomotaka Ugai, Keitaro Matsuo, Norie Sawada, Motoki Iwasaki, Taiki Yamaji, Taichi Shimazu, Shizuka Sasazuki, Manami Inoue, Yoshinobu Kanda, Shoichiro Tsugane
Background: The aim of this study was to investigate the association of coffee and green tea consumption and the risk of malignant lymphoma and multiple myeloma in a large-scale population-based cohort study in Japan.Methods: In this analysis, a total of 95,807 Japanese subjects (45,937 men and 49,870 women; ages 40-69 years at baseline) of the Japan Public Health Center-based Prospective Study who completed a questionnaire about their coffee and green tea consumption were followed up until December 31, 2012, for an average of 18 years...
August 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28757581/identification-of-urinary-polyphenol-metabolite-patterns-associated-with-polyphenol-rich-food-intake-in-adults-from-four-european-countries
#12
Hwayoung Noh, Heinz Freisling, Nada Assi, Raul Zamora-Ros, David Achaintre, Aurélie Affret, Francesca Mancini, Marie-Christine Boutron-Ruault, Anna Flögel, Heiner Boeing, Tilman Kühn, Ruth Schübel, Antonia Trichopoulou, Androniki Naska, Maria Kritikou, Domenico Palli, Valeria Pala, Rosario Tumino, Fulvio Ricceri, Maria Santucci de Magistris, Amanda Cross, Nadia Slimani, Augustin Scalbert, Pietro Ferrari
We identified urinary polyphenol metabolite patterns by a novel algorithm that combines dimension reduction and variable selection methods to explain polyphenol-rich food intake, and compared their respective performance with that of single biomarkers in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The study included 475 adults from four European countries (Germany, France, Italy, and Greece). Dietary intakes were assessed with 24-h dietary recalls (24-HDR) and dietary questionnaires (DQ)...
July 25, 2017: Nutrients
https://www.readbyqxmd.com/read/28751477/associations-of-coffee-drinking-and-cancer-mortality-in-the-cancer-prevention-study-ii
#13
Susan M Gapstur, Rebecca L Anderson, Peter T Campbell, Eric J Jacobs, Terryl J Hartman, Janet S Hildebrand, Ying Wang, Marjorie L McCullough
BACKGROUND: Associations of coffee consumption with cancer mortality are inconsistent for many types of cancer, and confounding by smoking is an important concern. METHODS: Cox proportional hazards regression was used to estimate multivariable-adjusted hazard ratios (HR) for coffee consumption associated with death from all cancers combined and from specific cancer types among 922,896 Cancer Prevention Study-II participants aged 28-94 years who completed a four-page questionnaire and were cancer free at baseline in 1982...
July 27, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28746796/association-of-coffee-consumption-with-all-sites-cancer-incidence-and-mortality
#14
Junya Sado, Tetsuhisa Kitamura, Yuri Kitamura, Tomotaka Sobue, Yoshikazu Nishino, Hideo Tanaka, Tomio Nakayama, Ichiro Tsuji, Hidemi Ito, Takaichiro Suzuki, Kota Katanoda, Suketami Tominaga
The preventive effect of coffee on cancer at different sites has been reported, although the effect on all-sites cancer incidence has not been extensively investigated. We evaluated the association between frequency of coffee consumption and risk of all-sites cancer incidence and mortality among 39,685 men and 43,124 women (age 40 to 79 years, at baseline), in the Three Prefecture Cohort Study. The association between frequency of coffee consumption and risk of all-sites cancer incidence and mortality was assessed by a Cox proportional hazards regression model, adjusted for potential confounders...
July 26, 2017: Cancer Science
https://www.readbyqxmd.com/read/28733869/bmi-is-a-risk-factor-for-colorectal-cancer-mortality
#15
Aasma Shaukat, Allison Dostal, Jeremiah Menk, Timothy R Church
BACKGROUND: The relationship between dietary and lifestyle risk factors and long-term mortality from colorectal cancer is poorly understood. Several factors, such as obesity, intakes of red meat, and use of aspirin, have been reported to be associated with risk of colorectal cancer mortality, though these findings have not been replicated in all studies to date. METHODS: In the Minnesota Colon Cancer Control Study, 46,551 participants 50-80 years old were randomly assigned to usual care (control) or annual or biennial screening by fecal occult blood testing...
July 21, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28719146/natural-compounds-in-cancer-prevention-effects-of-coffee-extracts-and-their-main-polyphenolic-component-5-o-caffeoylquinic-acid-on-oncogenic-ras-proteins
#16
Alessandro Palmioli, Carlotta Ciaramelli, Renata Tisi, Michela Spinelli, Gaia De Sanctis, Elena Sacco, Cristina Airoldi
Recent epidemiological studies have demonstrated that the consumption of healthy foods that are particularly rich in polyphenols might reduce the incidence of cancer and neurodegenerative diseases. In particular, chlorogenic acids (CGAs) occur ubiquitously in food and represent the most abundant polyphenols in the human diet. A number of beneficial biological effects of CGAs, such as anti-inflammatory activity, anti-carcinogenic activity, and protection against neurodegenerative diseases, have been reported...
July 18, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28699042/is-the-non-sentinel-lymph-node-compartment-the-next-site-for-melanoma-progression-from-the-sentinel-lymph-node-compartment-in-the-regional-nodal-basin
#17
Andrei Rios-Cantu, Ying Lu, Victor Melendez-Elizondo, Michael Chen, Alejandra Gutierrez-Range, Niloofar Fadaki, Suresh Thummala, Carla West-Coffee, James Cleaver, Mohammed Kashani-Sabet, Stanley P L Leong
Melanoma patients with additional positive lymph nodes in the completion lymph node dissection (CLND) following a positive sentinel lymph node (SLN) biopsy would have a poorer prognosis than patients with no additional positive lymph nodes. We hypothesize that the progression of disease from the SLN to the non-SLN compartment is orderly and is associated with the worsening of the disease status. Thus, the SLN and non-SLN compartments are biologically different in that cancer cells, in general, arrive in the SLN compartment before spreading to the non-SLN compartment...
July 11, 2017: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/28698757/new-safety-margins-for-melanoma-surgery-nice-possibility-for-drinking-of-just-that-cup-of-coffee
#18
Georgi Tchernev, Anastasiya Atanasova Chokoeva
BACKGROUND: The American Joint Committee on Cancer (AJCC's) skin melanoma surgical treatment recommendations from 2011 are characterised by a prima facie "freedom of choice" regarding how extensive should be the excisions for melanomas with tumour thickness up to 2 mm and melanoma in situ. It is unclear why the recommended surgical security margins vary between 0.5 and 1 cm for melanoma in situ, whereas for melanomas with a tumour thickness of up to 1.99 mm, the range of variation is also between 1 and 2 cm, without specifying when the surgical field should be broader and, narrower, accordingly...
June 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28693281/coffee-reduces-kras-expression-in-caco-2-human-colon-carcinoma-cells-via-regulation-of-mirnas
#19
Takuya Nakayama, Megumi Funakoshi-Tago, Hiroomi Tamura
Previous epidemiological studies have demonstrated that moderate coffee consumption is associated with a lower risk of certain types of cancer, particularly colon cancer. To elucidate the molecular basis for this protective action, the effect of coffee on Caco-2 human colon carcinoma cells was investigated. Low concentrations of coffee (<5%) inhibited proliferation of Caco-2 cells without affecting cell viability. Coffee also reduced KRAS proto-oncogene, GTPase (KRAS) gene expression in a dose-dependent manner; however, caffeine, caffeic acid and chlorogenic acid, three major constituents of coffee, did not exhibit this effect...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28693038/coffee-drinking-and-mortality-in-10-european-countries-a-multinational-cohort-study
#20
Marc J Gunter, Neil Murphy, Amanda J Cross, Laure Dossus, Laureen Dartois, Guy Fagherazzi, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Krasimira Aleksandrova, Anne Tjønneland, Anja Olsen, Kim Overvad, Sofus Christian Larsen, Maria Luisa Redondo Cornejo, Antonio Agudo, María José Sánchez Pérez, Jone M Altzibar, Carmen Navarro, Eva Ardanaz, Kay-Tee Khaw, Adam Butterworth, Kathryn E Bradbury, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sara Grioni, Paolo Vineis, Salvatore Panico, Rosario Tumino, Bas Bueno-de-Mesquita, Peter Siersema, Max Leenders, Joline W J Beulens, Cuno U Uiterwaal, Peter Wallström, Lena Maria Nilsson, Rikard Landberg, Elisabete Weiderpass, Guri Skeie, Tonje Braaten, Paul Brennan, Idlir Licaj, David C Muller, Rashmi Sinha, Nick Wareham, Elio Riboli
Background: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective: To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Design: Prospective cohort study. Setting: 10 European countries. Participants: 521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition)...
August 15, 2017: Annals of Internal Medicine
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