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https://www.readbyqxmd.com/read/28809372/coffee-is-protective-against-oral-and-pharyngeal-cancer-a-systematic-review-and-meta-analysis
#1
J Miranda, L Monteiro, R Albuquerque, J-J Pacheco, Z Khan, J Lopez-Lopez, S Warnakulasuryia
OBJECTIVES: Coffee is one of the most popular and consumable drinks worldwide. However, there are conflicting results on the influence of this drink in oral and pharyngeal cancer risk. To clarify this, we aimed to systemically review and carry out a meta-analysis of the relevant literature on the association between coffee and oral and pharyngeal cancer. STUDY DESIGN: We carried out an electronic search of publications up to August 2016 from PubMed, National Library of Medicines Medline, Embase, Science Direct and the Cochrane Central Register...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28804505/an-etiologic-prediction-model-incorporating-biomarkers-to-predict-the-bladder-cancer-risk-associated-with-occupational-exposure-to-aromatic-amines-a-pilot-study
#2
Giuseppe Mastrangelo, Angela Carta, Cecilia Arici, Sofia Pavanello, Stefano Porru
BACKGROUND: No etiological prediction model incorporating biomarkers is available to predict bladder cancer risk associated with occupational exposure to aromatic amines. METHODS: Cases were 199 bladder cancer patients. Clinical, laboratory and genetic data were predictors in logistic regression models (full and short) in which the dependent variable was 1 for 15 patients with aromatic amines related bladder cancer and 0 otherwise. The receiver operating characteristics approach was adopted; the area under the curve was used to evaluate discriminatory ability of models...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28768299/a-prospective-investigation-of-coffee-drinking-and-bladder-cancer-incidence-in-the-united-states
#3
Erikka Loftfield, Neal D Freedman, Maki Inoue-Choi, Barry I Graubard, Rashmi Sinha
BACKGROUND: In 1991, coffee was classified as a group 2B carcinogen, possibly carcinogenic to humans, based on limited epidemiologic evidence of a positive association with bladder cancer. In 2016, the International Agency for Research on Cancer downgraded this classification due to lack of evidence from prospective studies particularly for never smokers. METHODS: Baseline coffee drinking was assessed with a food frequency questionnaire in the NIH-AARP prospective cohort study...
September 2017: Epidemiology
https://www.readbyqxmd.com/read/28765341/coffee-and-green-tea-consumption-and-subsequent-risk-of-malignant-lymphoma-and-multiple-myeloma-in-japan-the-japan-public-health-center-based-prospective-study
#4
Tomotaka Ugai, Keitaro Matsuo, Norie Sawada, Motoki Iwasaki, Taiki Yamaji, Taichi Shimazu, Shizuka Sasazuki, Manami Inoue, Yoshinobu Kanda, Shoichiro Tsugane
Background: The aim of this study was to investigate the association of coffee and green tea consumption and the risk of malignant lymphoma and multiple myeloma in a large-scale population-based cohort study in Japan.Methods: In this analysis, a total of 95,807 Japanese subjects (45,937 men and 49,870 women; ages 40-69 years at baseline) of the Japan Public Health Center-based Prospective Study who completed a questionnaire about their coffee and green tea consumption were followed up until December 31, 2012, for an average of 18 years...
August 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28757581/identification-of-urinary-polyphenol-metabolite-patterns-associated-with-polyphenol-rich-food-intake-in-adults-from-four-european-countries
#5
Hwayoung Noh, Heinz Freisling, Nada Assi, Raul Zamora-Ros, David Achaintre, Aurélie Affret, Francesca Mancini, Marie-Christine Boutron-Ruault, Anna Flögel, Heiner Boeing, Tilman Kühn, Ruth Schübel, Antonia Trichopoulou, Androniki Naska, Maria Kritikou, Domenico Palli, Valeria Pala, Rosario Tumino, Fulvio Ricceri, Maria Santucci de Magistris, Amanda Cross, Nadia Slimani, Augustin Scalbert, Pietro Ferrari
We identified urinary polyphenol metabolite patterns by a novel algorithm that combines dimension reduction and variable selection methods to explain polyphenol-rich food intake, and compared their respective performance with that of single biomarkers in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The study included 475 adults from four European countries (Germany, France, Italy, and Greece). Dietary intakes were assessed with 24-h dietary recalls (24-HDR) and dietary questionnaires (DQ)...
July 25, 2017: Nutrients
https://www.readbyqxmd.com/read/28751477/associations-of-coffee-drinking-and-cancer-mortality-in-the-cancer-prevention-study-ii
#6
Susan M Gapstur, Rebecca L Anderson, Peter T Campbell, Eric J Jacobs, Terryl J Hartman, Janet S Hildebrand, Ying Wang, Marjorie L McCullough
BACKGROUND: Associations of coffee consumption with cancer mortality are inconsistent for many types of cancer, and confounding by smoking is an important concern. METHODS: Cox proportional hazards regression was used to estimate multivariable-adjusted hazard ratios (HR) for coffee consumption associated with death from all cancers combined and from specific cancer types among 922,896 Cancer Prevention Study-II participants aged 28-94 years who completed a four-page questionnaire and were cancer free at baseline in 1982...
July 27, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28746796/association-of-coffee-consumption-with-all-sites-cancer-incidence-and-mortality
#7
Junya Sado, Tetsuhisa Kitamura, Yuri Kitamura, Tomotaka Sobue, Yoshikazu Nishino, Hideo Tanaka, Tomio Nakayama, Ichiro Tsuji, Hidemi Ito, Takaichiro Suzuki, Kota Katanoda, Suketami Tominaga
The preventive effect of coffee on cancer at different sites has been reported, although the effect on all-sites cancer incidence has not been extensively investigated. We evaluated the association between frequency of coffee consumption and risk of all-sites cancer incidence and mortality among 39,685 men and 43,124 women (age 40 to 79 years, at baseline), in the Three Prefecture Cohort Study. The association between frequency of coffee consumption and risk of all-sites cancer incidence and mortality was assessed by a Cox proportional hazards regression model, adjusted for potential confounders...
July 26, 2017: Cancer Science
https://www.readbyqxmd.com/read/28733869/bmi-is-a-risk-factor-for-colorectal-cancer-mortality
#8
Aasma Shaukat, Allison Dostal, Jeremiah Menk, Timothy R Church
BACKGROUND: The relationship between dietary and lifestyle risk factors and long-term mortality from colorectal cancer is poorly understood. Several factors, such as obesity, intakes of red meat, and use of aspirin, have been reported to be associated with risk of colorectal cancer mortality, though these findings have not been replicated in all studies to date. METHODS: In the Minnesota Colon Cancer Control Study, 46,551 participants 50-80 years old were randomly assigned to usual care (control) or annual or biennial screening by fecal occult blood testing...
July 21, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28719146/natural-compounds-in-cancer-prevention-effects-of-coffee-extracts-and-their-main-polyphenolic-component-5-cqa-on-oncogenic-ras-proteins
#9
Alessandro Palmioli, Carlotta Cairamelli, Renata Tisi, Michela Spinelli, Gaia De Sanctis, Elena Sacco, Cristina Airoldi
Recent epidemiological studies demonstrate that consumption of healthy foods, especially rich in polyphenols content, might reduce the incidence of cancer and degenerative diseases. In particular, chlorogenic acids (CGAs) occur ubiquitously in food, representing the most abundant polyphenols in the human diet. A number of CGA beneficial biological effects, including anti-inflammatory activity, anti-carcinogenic activity and protection against neurodegenerative diseases have been reported. However, the molecular mechanisms at the basis of these biological activities have not yet been investigated in depth...
July 18, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28699042/is-the-non-sentinel-lymph-node-compartment-the-next-site-for-melanoma-progression-from-the-sentinel-lymph-node-compartment-in-the-regional-nodal-basin
#10
Andrei Rios-Cantu, Ying Lu, Victor Melendez-Elizondo, Michael Chen, Alejandra Gutierrez-Range, Niloofar Fadaki, Suresh Thummala, Carla West-Coffee, James Cleaver, Mohammed Kashani-Sabet, Stanley P L Leong
Melanoma patients with additional positive lymph nodes in the completion lymph node dissection (CLND) following a positive sentinel lymph node (SLN) biopsy would have a poorer prognosis than patients with no additional positive lymph nodes. We hypothesize that the progression of disease from the SLN to the non-SLN compartment is orderly and is associated with the worsening of the disease status. Thus, the SLN and non-SLN compartments are biologically different in that cancer cells, in general, arrive in the SLN compartment before spreading to the non-SLN compartment...
July 11, 2017: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/28698757/new-safety-margins-for-melanoma-surgery-nice-possibility-for-drinking-of-just-that-cup-of-coffee
#11
Georgi Tchernev, Anastasiya Atanasova Chokoeva
BACKGROUND: The American Joint Committee on Cancer (AJCC's) skin melanoma surgical treatment recommendations from 2011 are characterised by a prima facie "freedom of choice" regarding how extensive should be the excisions for melanomas with tumour thickness up to 2 mm and melanoma in situ. It is unclear why the recommended surgical security margins vary between 0.5 and 1 cm for melanoma in situ, whereas for melanomas with a tumour thickness of up to 1.99 mm, the range of variation is also between 1 and 2 cm, without specifying when the surgical field should be broader and, narrower, accordingly...
June 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28693281/coffee-reduces-kras-expression-in-caco-2-human-colon-carcinoma-cells-via-regulation-of-mirnas
#12
Takuya Nakayama, Megumi Funakoshi-Tago, Hiroomi Tamura
Previous epidemiological studies have demonstrated that moderate coffee consumption is associated with a lower risk of certain types of cancer, particularly colon cancer. To elucidate the molecular basis for this protective action, the effect of coffee on Caco-2 human colon carcinoma cells was investigated. Low concentrations of coffee (<5%) inhibited proliferation of Caco-2 cells without affecting cell viability. Coffee also reduced KRAS proto-oncogene, GTPase (KRAS) gene expression in a dose-dependent manner; however, caffeine, caffeic acid and chlorogenic acid, three major constituents of coffee, did not exhibit this effect...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28693038/coffee-drinking-and-mortality-in-10-european-countries-a-multinational-cohort-study
#13
Marc J Gunter, Neil Murphy, Amanda J Cross, Laure Dossus, Laureen Dartois, Guy Fagherazzi, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Krasimira Aleksandrova, Anne Tjønneland, Anja Olsen, Kim Overvad, Sofus Christian Larsen, Maria Luisa Redondo Cornejo, Antonio Agudo, María José Sánchez Pérez, Jone M Altzibar, Carmen Navarro, Eva Ardanaz, Kay-Tee Khaw, Adam Butterworth, Kathryn E Bradbury, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sara Grioni, Paolo Vineis, Salvatore Panico, Rosario Tumino, Bas Bueno-de-Mesquita, Peter Siersema, Max Leenders, Joline W J Beulens, Cuno U Uiterwaal, Peter Wallström, Lena Maria Nilsson, Rikard Landberg, Elisabete Weiderpass, Guri Skeie, Tonje Braaten, Paul Brennan, Idlir Licaj, David C Muller, Rashmi Sinha, Nick Wareham, Elio Riboli
Background: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective: To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Design: Prospective cohort study. Setting: 10 European countries. Participants: 521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition)...
August 15, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28693036/association-of-coffee-consumption-with-total-and-cause-specific-mortality-among-nonwhite-populations
#14
Song-Yi Park, Neal D Freedman, Christopher A Haiman, Loïc Le Marchand, Lynne R Wilkens, Veronica Wendy Setiawan
Background: Coffee consumption has been associated with reduced risk for death in prospective cohort studies; however, data in nonwhites are sparse. Objective: To examine the association of coffee consumption with risk for total and cause-specific death. Design: The MEC (Multiethnic Cohort), a prospective population-based cohort study established between 1993 and 1996. Setting: Hawaii and Los Angeles, California. Participants: 185 855 African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites aged 45 to 75 years at recruitment...
August 15, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28668478/preliminary-evidence-of-polymorphisms-of-cell-cycle-regulatory-genes-and-their-roles-in-urinary-tract-urothelial-cancer-susceptibility-and-prognosis-in-a-taiwan-population
#15
Ying-Chu Lin, Tzyh-Chyuan Hour, Yu-Chieh Tsai, Shu-Pin Huang, Wen-Jeng Wu, Chung-Hsin Chen, Yeong-Shiau Pu, Shiu-Dong Chung, Chao-Yuan Huang
OBJECTIVE: Our aims were to investigate the correlations between polymorphisms in the cell cycle regulatory genes (aurora kinase A [AURKA], survivin, p21, and p53) and UC risk and prognosis. PATIENTS AND METHODS: This study recruited 185 patients with UTUC, 46 patients with bladder cancer, and 188 hospital controls. Demographic data and possible confounding factors were collected using a standardized questionnaire. Genotyping was determined by real-time polymerase chain reaction and TaqMan probe methods...
June 28, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28662634/healthy-dietary-patterns-decrease-the-risk-of-colorectal-cancer-in-the-mecca-region-saudi-arabia-a-case-control-study
#16
Firas S Azzeh, Eyad M Alshammari, Awfa Y Alazzeh, Abdelelah S Jazar, Ibrahim R Dabbour, Hani A El-Taani, Ahmed A Obeidat, Fayrooz A Kattan, Sufyan H Tashtoush
BACKGROUND: Colorectal cancer (CRC) is the first most common cancer in males and the third most common cancer in females in Saudi Arabia. Dietary habits are strongly associated with the inhibition or proliferation of malignancy. Therefore, this study is aiming to investigate the risks and protective benefits of dietary factors affecting CRC in the Mecca region of Saudi Arabia. METHODS: A case-control study was conducted from June 2014 to March 2015. One hundred thirty-seven patients with colon and/or rectal cancer were recruited in the case group, while 164 healthy participants were recruited in the control group...
June 29, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28624617/core-shell-iron-oxide-layered-double-hydroxide-high-electrochemical-sensing-performance-of-h2o2-biomarker-in-live-cancer-cells-with-plasma-therapeutics
#17
Muhammad Asif, Hongwei Liu, Ayesha Aziz, Haitao Wang, Zhengyun Wang, Muhammad Ajmal, Fei Xiao, Hongfang Liu
In this work, we develop a new type of multifunctional core-shell nanomaterial by controllable integration of CuAl layered double hydroxides (LDHs) over the surface of iron oxides (Fe3O4) nanospheres (NSs) to fabricate (Fe3O4@CuAl NSs) hybrid material with interior tunability of LDH phase and explore its practical application in ultrasensitive detection of emerging biomarker, i.e., H2O2 as cancer diagnostic probe. In addition, atmospheric pressure plasmas (APPs) have also been used as potential therapeutic approach for cancer treatment...
June 3, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28612129/coffee-consumption-and-risk-of-non-hodgkin-s-lymphoma-evidence-from-the-italian-multicentre-case-control-study
#18
Stefano Parodi, Franco Domenico Merlo, Emanuele Stagnaro
PURPOSE: Several investigations have analysed the association between coffee intake and risk of cancer. Contradictory results were reported by the studies conducted in non-Hodgkin's lymphomas (NHL) few of which report results according to main NHL subgroups. The present study is aimed at evaluating the association between coffee consumption and the risk of NHL by analysing data from a large Italian multicentre case-control study that included 1,418 interviewed cases (1,301 B cell and 117 T cell NHL), diagnosed between 1990 and 1993, and 1,774 population healthy controls...
August 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28588600/date-palm-tree-phoenix-dactylifera-l-natural-products-and-therapeutic-options
#19
REVIEW
Reem A Al-Alawi, Jawhara H Al-Mashiqri, Jawaher S M Al-Nadabi, Badria I Al-Shihi, Younis Baqi
Many plants, including some of the commonly consumed herbs and spices in our daily food, can be safely and effectively used to prevent and/or treat some health concerns. For example, caffeine the active ingredient found in coffee beans (Coffea), shows biological activity in the treatment of the central nervous system (CNS) disorders, indole-3-carbinol, and 3,3'-diindolylmethane are both broccoli (Brassica oleracea) derived phytochemicals with potential anti-cancer activity, and resveratrol, isolated from grape (Vitis vinifera), is reported to extend lifespan and provide cardio-neuro-protective, anti-diabetic, and anti-cancer effects...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28578041/microbiota-source-impact-in-vitro-metabolite-colonic-production-and-anti-proliferative-effect-of-spent-coffee-grounds-on-human-colon-cancer-cells-ht-29
#20
Angélica María Hernández-Arriaga, B Dave Oomah, Rocio Campos-Vega
Human gut flora-mediated non-digestible fraction of spent coffee grounds (hgf-NDSCG) was evaluated for its chemopreventive effect and molecular mechanisms involved on human colon adenocarcinoma HT-29 cell survival using two different microbiota source [lean (L) and overweight (OW)]. The source of human gut flora (hgf) (L or OW) affected the pH of hgf-NDSCG only minimally, but linearly reduced those of hgf-inulin. The variability between lean and overweight microbiota was characterized by the metabolism and/or bioaccessibility of different phenolic metabolites, their intermediate and end products as well as by variable time courses...
July 2017: Food Research International
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