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https://www.readbyqxmd.com/read/28823072/prevalence-and-predictors-of-digoxin-utilization-among-heart-failure-patients-with-reduced-ejection-fraction-in-qatar
#1
Alaa Abdullah Rahhal, Ahmed Awaisu, Kawthar M Tawengi, Safae AbuYousef, Lylia Mekideche
Background Digoxin is a cardiac glycoside that is recommended by clinical practice guidelines to be used in patients with heart failure with reduced ejection fraction (HFrEF) who still have persistent symptoms despite optimal medical therapy. However, this recommendation is based on limited and old trial data. Moreover, pharmacoepidemiologic studies are important in determining the prevalence of digoxin use and factors influencing this. Objective This study aimed to determine the prevalence and the predictors of digoxin utilization among patients with HFrEF with or without atrial fibrillation (AF) in Qatar...
August 19, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28823004/the-influence-of-ocular-sighting-dominance-on-fundus-torsion-in-patients-with-unilateral-congenital-superior-oblique-palsy
#2
Dae Hee Kim, Hyuna Kim, Hyun Taek Lim
PURPOSE: The purpose of our study was to determine whether ocular sighting dominance may influence the ocular torsion in patients with unilateral congenital superior oblique palsy (UCSOP). METHODS: This retrospective study included 22 UCSOP patients with radiologic evidence of unilateral superior oblique muscle hypoplasia on orbital magnetic resonance imaging and 66 healthy individuals with normal ocular motility as controls. Ocular torsion was assessed both quantitatively and qualitatively using digital fundus photography...
August 19, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28822999/preservation-of-remnant-with-poor-synovial-coverage-has-no-beneficial-effect-over-remnant-sacrifice-in-anterior-cruciate-ligament-reconstruction
#3
Bo Hyun Kim, Joong Il Kim, Osung Lee, Ki Woung Lee, Myung Chul Lee, Hyuk Soo Han
PURPOSE: The purpose of the study was to evaluate the influence of synovial coverage of the remnant on clinical outcomes and graft healing in anterior cruciate ligament (ACL) reconstruction. METHODS: Seventy-five patients who underwent second-look arthroscopy after a single-bundle ACL reconstruction using autologous quadriceps tendon graft were included. The patients were divided into two groups according to whether the remnant was preserved (group P, n = 42) or sacrificed (group S, n = 33)...
August 19, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28822943/sound-side-joint-contact-forces-in-below-knee-amputee-gait-with-an-esar-prosthetic-foot
#4
Mohammad Taghi Karimi, Firooz Salami, Amir Esrafilian, Daniel W W Heitzmann, Merkur Alimusaj, Cornelia Putz, Sebastian I Wolf
The incidence of knee and hip joint osteoarthritis in subjects with below knee amputation (BK) appears significantly higher compared to unimpaired subjects, especially in the intact side. However, it is controversial if constant higher loads on the sound side are one of the major factors for an increased osteoarthritis (OA) incidence in subjects with BK, beside other risk factors, e.g. with respect to metabolism. The aim wasto investigate joint contact forces (JCF) calculated by a musculoskeletal model in the intact side and to compare it with those of unimpaired subjects and to further elucidate in how far increased knee JCF are associated with increased frontal plane knee moments...
August 8, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28822935/assessing-urban-population-vulnerability-and-environmental-risks-across-an-urban-area-during-heatwaves-implications-for-health-protection
#5
H L Macintyre, C Heaviside, J Taylor, R Picetti, P Symonds, X-M Cai, S Vardoulakis
Heatwaves can lead to a range of adverse impacts including increased risk of illness and mortality; the heatwave in August 2003 has been associated with ~70,000 deaths across Europe. Due to climate change, heatwaves are likely to become more intense, more frequent and last longer in the future. A number of factors may influence risks associated with heat exposure, such as population age, housing type, and location within the Urban Heat Island, and such factors may not be evenly distributed spatially across a region...
August 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822902/pregnancy-outcome-is-influenced-by-luteal-area-during-diestrus-before-successful-insemination-but-not-by-milk-production-level
#6
H Berger, M Lietzau, A Tichy, K Herzog
The objective was to compare luteal area (LA), luteal blood flow (LBF), and progesterone (P4) concentration before and after artificial insemination (AI) in pregnant and open cows in the diestrus preceding insemination and during the first 21 d after insemination. A number of 119 multiparous German Holstein cows were examined using B-mode and color Doppler sonography in diestrus (15-5 d before AI) and on days 7, 14, and 21 post insemination (pi). Blood samples for determination of P4 concentration were collected at each examination...
April 14, 2017: Theriogenology
https://www.readbyqxmd.com/read/28822867/de-novo-assembly-and-characterization-of-seabass-lateolabrax-japonicus-transcriptome-and-expression-of-hepatic-genes-following-different-dietary-phosphorus-calcium-levels
#7
Kang-Le Lu, Zhong-Li Ji, Samad Rahimnejad, Chun-Xiao Zhang, Ling Wang, Kai Song
Fish farming seriously influences the aquatic environment because most dietary phosphorus (P) is excreted in the effluent. To increase the P utilization in fish, molecular techniques should be explored given the remarkable development of these techniques. Thus, to identify the candidate genes related to P utilization and molecular alterations following administration of a P-deficient diet in seabass Lateolabrax japonicus, we assessed the de novo pituitary, gill, intestine, liver, kidney, scales and vertebra transcriptomes, and we compared the expression of hepatic genes with three diets varying in P and Ca levels: diet I (0...
August 9, 2017: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/28822799/effect-of-application-sequence-of-fluoride-and-cpp-acp-on-remineralization-of-white-spot-lesions-in-primary-teeth-an-in-vitro-study
#8
Ola B Al-Batayneh, Reem A Jbarat, Susan N Al-Khateeb
OBJECTIVE: To explore how application sequence of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride influences remineralization of enamel white spot lesions (WSL) in primary teeth. DESIGN: In this in-vitro study, artificial WSLs were created in 130 primary teeth. Teeth were divided into 4 groups (n=27) and a control group (n=22) and exposed to one of the following remineralization regimens for 10 weeks: Group-1; 500ppm fluoride dentifrice; Group-2; 10% w/v CPP-ACP; Group-3; fluoride applied first, then CPP-ACP; Group-4; CPP-ACP applied first, then fluoride, and Group-5 was control...
August 10, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28822797/influence-of-bcr-abl-transcript-type-on-outcome-in-patients-with-chronic-phase-chronic-myeloid-leukemia-treated-with%C3%A2-imatinib
#9
Katia Borgia Barbosa Pagnano, Eliana Cristina Miranda, Márcia Torresan Delamain, Gislaine Oliveira Duarte, Erich Vinicius de Paula, Irene Lorand-Metze, Carmino Antonio de Souza
BACKGROUND: The prognostic significance of breakpoint cluster region gene-Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL1) transcripts in chronic myeloid leukemia (CML) is still controversial. PATIENTS AND METHODS: All consecutive CML patients in chronic phase treated with imatinib in a single center were analyzed (n = 170). BCR-ABL1 transcript was evaluated using multiplex reverse transcription polymerase chain reaction. Exclusively patients with BCR-ABL transcripts e13a2 and/or e14a2 were included in this analysis...
June 21, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28822760/anterior-chamber-perfusion-versus-posterior-chamber-perfusion-does-not-influence-measurement-of-aqueous-outflow-facility-in-living-mice-by-constant-flow-infusion
#10
Navita N Lopez, Gaurang C Patel, Urmimala Raychaudhuri, Subhash Aryal, Tien N Phan, Abbot F Clark, J Cameron Millar
Mice are now routinely utilized in studies of aqueous humor outflow dynamics. In particular, conventional aqueous outflow facility (C) is routinely measured via perfusion of the aqueous chamber by a number of laboratories. However, in mouse eyes perfused ex-vivo, values for C are variable depending upon whether the perfusate is introduced into the posterior chamber (PC) versus the anterior chamber (AC). Perfusion via the AC leads to posterior bowing of the iris, and traction on the iris root/scleral spur, which may increase C...
August 16, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28822755/does-the-transformation-of-dietitians-from-counseling-to-therapy-also-apply-to-the-physical-and-therapeutic-environment-a-case-study-of-israeli-practice
#11
Anat Gesser-Edelsburg, Yael Birman
BACKGROUND: Lifestyle change can be influenced through effective interaction between care receiver and care provider. The physical environment where the interaction occurs can affect the dynamics of long-term therapeutic treatment. There have been no studies on the perception of the physical environment in nutritional treatment. OBJECTIVE: Our aim was to ascertain the impact of the physical environment on the dynamics and communication between dietitian and patient based on perceptions of dietitians...
August 17, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28822694/sex-and-the-housing-effects-on-behavior-cortisol-levels-and-weight-in-zebrafish
#12
Gustavo Kellermann Reolon, Gabriela Madalena de Melo, João Gabriel Dos Santos da Rosa, Leonardo José Gil Barcellos, Carla Denise Bonan
Studies with zebrafish use acclimatizing periods of at least one week immediately before the experiments. During this time, animals can be housed in sexually segregated conditions (only females or males in the tank) or in mixed-sex conditions (both sexes in the tank). The influence of sex and housing conditions regarding the presence of one or two sexes is largely unknown in zebrafish. Our aim was to evaluate the influence that sex and housing regarding the sex of animals had in the open tank task, in the inhibitory avoidance memory test, in cortisol levels and weight in zebrafish...
August 16, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28822643/genetic-background-impacts-vaccine-induced-reduction-of-pneumococcal-colonization
#13
Kirsten Kuipers, Saskia van Selm, Fred van Opzeeland, Jeroen D Langereis, Lilly M Verhagen, Dimitri A Diavatopoulos, Marien I de Jonge
Vaccination has been one of the most successful strategies to reduce morbidity and mortality caused by respiratory infections. Recent evidence suggests that differences in the host genetic background and environmental factors may contribute to heterogeneity in the immune response to vaccination. During pre-clinical testing, vaccines are often evaluated in a single mouse inbred strain, which may not translate well to the heterogeneous human population. Here, we examined the influence of host genetic background on vaccine-induced protection against pneumococcal colonization in two commonly used inbred mouse strains, i...
August 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28822603/the-impact-of-hospital-volume-on-perioperative-outcomes-of-rectal-cancer
#14
F H W Jonker, J A W Hagemans, C Verhoef, J W A Burger
BACKGROUND: The purpose of this study was to investigate the impact of hospital volume on perioperative outcomes of clinical tumour stage (cT)1-3 and cT4 rectal cancer. METHODS: 16.162 patients operated for rectal cancer enrolled in the Dutch Surgical Colorectal Audit were included. Hospitals were divided into low (<20 cases/year), medium (21-50 cases/year) and high (>50 cases/year) volume for cT1-3 rectal cancer, and for cT4 rectal cancer into low (1-4 cases/year), medium (5-9 cases/year) and high (≥10 cases/year) volume...
July 29, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28822582/antibiofilm-properties-of-model-composites-containing-quaternary-ammonium-methacrylates-after-surface-texture-modification
#15
Guilherme Ferreira Rego, Marina Lermen Vidal, Gil Mendes Viana, Lucio Mendes Cabral, Luis Felipe Jochims Schneider, Maristela Barbosa Portela, Larissa Maria Cavalcante
OBJECTIVE: Investigate antimicrobial properties and surface texture of model composites with different concentration and alkyl chain length of quaternary ammonium monomers (QAS). METHODS: Monomers derived from QAS salts with alkyl chain lengths of 12 carbons ((dimethylaminododecyl methacrylate) DMADDM) and 16 carbons (dimethylaminohexadecyl methacrylate-DMAHDM) were obtained from the reactions of their respective organo-halides with the tertiary amine 2-(dimethylamino)ethyl methacrylate (DMAEMA)...
August 16, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28822565/the-influence-of-periodontal-status-on-endodontically-treated-teeth-9-year-survival-analysis
#16
Navid Khalighinejad, Anita Aminoshariae, James C Kulild, Jeannie Wang, Andre Mickel
INTRODUCTION: The aim of this study was to investigate the effect of periodontal status at the time of nonsurgical root canal treatment (NSRCT) on the survival rate of endodontically treated teeth (ETT). METHODS: In this retrospective investigation, molars that received NSRCT in an advanced specialty education program in endodontics from 2009 through 2017 were initially recruited. After the application of inclusion and exclusion criteria, 315 teeth were included in the study...
August 16, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28822553/vitamin-d-status-in-growing-dairy-goats-and-sheep-influence-of-ultraviolet-b-radiation-on-bone-metabolism-and-calcium-homeostasis
#17
M V Nemeth, M R Wilkens, A Liesegang
The aim of this study was to investigate how controlled UVB irradiation in combination with reduced nutritional vitamin D (vitD) supply affects vitD status and Ca metabolism of growing goats and sheep. The hypothesis was that, like dairy cows, goats and sheep are able to compensate for the missing nutritional supply of vitD through endogenous production in the skin, with the consequence of a high vitD status and a balanced Ca homeostasis. Sixteen lambs and 14 goat kids aged 3 and a half months were housed in an UVB free environment and fed hay and a vitD-free concentrate over a period of 13 wk...
August 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28822453/-influence-of-saccharomyces-boulardii-sachets-combined-with-bismuth-quadruple-therapy-for-initial-helicobacter-pylori-eradication
#18
X Y Zhu, J Du, J Wu, L W Zhao, X Meng, G F Liu
Objective: To evaluate the efficacy and safety of Saccharomyces boulardii Sachets combined with bismuth quadruple therapy for initial Helicobacter pylori(H.pylori) eradication. Methods: From March 2014 to March 2015, 240 participants from the third hospital of Hebei medical university with H. pylori infection were recruited and randomized into three groups: Quadruple therapy group received bismuth potassium citrate 220 mg bid + Rabeprazole 10 mg bid + amoxicillin 1 000 mg bid+ furazolidone 100 mg bid for 10 days...
August 8, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28822397/outcomes-after-mastectomy-and-lumpectomy-in-octogenarians-and-nonagenarians-with-early-stage-breast-cancer
#19
Amelia Y Merrill, Doris R Brown, Heidi D Klepin, Edward A Levine, Marissa Howard-Mcnatt
Prospective studies have shown equal outcomes after mastectomy or breast conservation in patients with invasive breast cancer; however, many of these studies excluded elderly patients. We identified patients in their eighties and nineties with clinical stage 0 to II breast cancer undergoing mastectomy or lumpectomy with or without radiation from the prospective sentinel lymph node database at Wake Forest Baptist Health and analyzed their treatment and survival. Of 92 patients, 24 (26.1%) underwent mastectomy, 22 (23...
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28822353/vdr-gene-variation-and-insulin-resistance-related-diseases
#20
Fei-Fei Han, Ya-Li Lv, Li-Li Gong, He Liu, Zi-Rui Wan, Li-Hong Liu
BACKGROUND: Vitamin D status may influence the risk of Insulin resistance related diseases such as Type 2 diabetes (T2DM), metabolic syndrome (MetS), and polycystic ovarian syndrome (PCOS). Several studies have assessed vitamin D receptor (VDR) gene polymorphism in relationship with these diseases; however, results remain inconsistent. Our study was conducted to elucidate whether VDR Gene polymorphisms could predict insulin resistance on a large scale. METHODS: A meta-analysis using MEDLINE and EMBASE, was performed up to December 16th, 2016...
August 19, 2017: Lipids in Health and Disease
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