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https://www.readbyqxmd.com/read/28079699/a-new-technique-for-total-reconstruction-of-the-lower-lid
#1
Mehmet Mutaf, Metin Temel
BACKGROUND: Although several methods have been described for total lower eyelid reconstruction, it remains as a major challenge in reconstructive surgery. Here, we present a new technique, the Mutaf unequal Z-plasty procedure for reconstruction of defects of the lower eyelid. METHODS: In this technique, 2 skin flaps designed in an unequal Z-plasty manner are used to provide skin coverage. Except for 2 patients whose additional upper eyelid defects were closed with Fricke flap, all patients were reconstructed with Mutaf unequal Z-plasty procedure...
February 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28077650/melanin-or-melanin-like-substance-interacts-with-the-n-terminal-portion-of-prion-protein-and-inhibits-abnormal-prion-protein-formation-in-prion-infected-cells
#2
Taichi Hamanaka, Keiko Nishizawa, Yuji Sakasegawa, Ayumi Oguma, Kenta Teruya, Hiroshi Kurahashi, Hideyuki Hara, Suehiro Sakaguchi, Katsumi Doh-Ura
Prion diseases are progressive fatal neurodegenerative illnesses caused by the accumulation of transmissible abnormal prion protein (PrP). To find treatments for prion diseases, we searched for substances from natural resources that inhibit abnormal PrP formation in prion-infected cells. We found that high-molecular-weight components from insect cuticle extracts reduced abnormal PrP levels. The chemical nature of these components was consistent with that of melanin. In fact, synthetic melanin produced from tyrosine or 3-hydroxy-l-tyrosine inhibited abnormal PrP formation...
January 11, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28076252/a-clinical-aid-for-detecting-skin-cancer-the-triage-amalgamated-dermoscopic-algorithm-tada
#3
T Rogers, M L Marino, S W Dusza, S Bajaj, R P Usatine, M A Marchetti, A A Marghoob
PURPOSE: Family physicians (FPs) frequently evaluate skin lesions but may not have the necessary training to accurately and confidently identify lesions that require skin biopsy or specialist referral. We evaluated the diagnostic performance of a new, simplified dermoscopy algorithm for skin cancer detection. METHODS: In this cross-sectional, observation study, attendees of a dermoscopy course evaluated 50 polarized dermoscopy images of skin lesions (27 malignant and 23 benign) using the Triage Amalgamated Dermoscopic Algorithm (TADA)...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28073339/dermal-safety-assessment-of-arm-hammer-laundry-products-formulated-for-sensitive-skin
#4
Douglas M Frederick, Linda Vorwerk, Archana Gupta, Annahita Ghassemi
CONTEXT: The prevalence of sensitive skin among the general population in industrialized countries is reported to be over 50%. Sensitive skin subjects often report significant reactions to contact with cosmetics, soaps and other consumer products. OBJECTIVE: This paper describes the overall skin compatibility and mildness program for a newly developed, lightly fragranced, colorant free laundry product (i.e. Arm & Hammer™ Sensitive Skin plus Skin-Friendly Fresh Scent), specially formulated for individuals with sensitive skin...
January 11, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28071843/automated-measurement-of-pressure-injury-through-image-processing
#5
Dan Li, Carol Mathews
AIMS AND OBJECTIVES: Develop an image processing algorithm to automatically measure pressure injuries using electronic pressure injury images stored in nursing documentation. BACKGROUND: Photographing pressure injuries and storing the images in the electronic health record is standard practice in many hospitals. However, the manual measurement of pressure injury is time-consuming, challenging, and subject to intra-inter-reader variability with complexities of the pressure injury and the clinical environment...
January 10, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28054350/daily-variation-of-uv-induced-erythema-and-the-action-of-solar-filters
#6
Ana Flo, Ana C Calpena, Antoni Díez-Noguera, Alfons Del Pozo, Trinitat Cambras
UV rays may cause several degrees of skin damage, which makes sunscreen research necessary. In addition, skin sensitivity shows daily variations, which can interfere in the detection of the efficacy of the filters. Here, we studied the UV-induced erythema in hairless rats at two times of the day (light and darkness) using a colorimeter method. The effect of an emulsion with solar filters with or without melatonin was also assayed. Results indicate that the value of a* (from CIELAB color space values L* a* b) was the most useful variable to evaluate the erythema...
November 16, 2016: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28052103/bmi-and-whr-are-reflected-in-female-facial-shape-and-texture-a-geometric-morphometric-image-analysis
#7
Christine Mayer, Sonja Windhager, Katrin Schaefer, Philipp Mitteroecker
Facial markers of body composition are frequently studied in evolutionary psychology and are important in computational and forensic face recognition. We assessed the association of body mass index (BMI) and waist-to-hip ratio (WHR) with facial shape and texture (color pattern) in a sample of young Middle European women by a combination of geometric morphometrics and image analysis. Faces of women with high BMI had a wider and rounder facial outline relative to the size of the eyes and lips, and relatively lower eyebrows...
2017: PloS One
https://www.readbyqxmd.com/read/28051251/observation-of-clinical-efficacy-of-rt-pa-intravenous-thrombolytic-treatment-for-patients-combined-with-grade-0-1-diabetic-foot-by-wagner-classification-and-acute-ischemic-stroke
#8
C-H Li, Y Chen, C-H Zhang, Z Dong, Z Wang, S-N Zhao, Y-X Wang, Z-Y Lv, P-L Zhang
OBJECTIVE: To evaluate the safety and efficacy of rt-PA intravenous thrombolytic treatment for patients with diabetic foot (DF) and acute ischemic stroke. PATIENTS AND METHODS: A retrospective analysis was performed on 76 patients admitted between June 2012 to December 2015 presenting with acute ischemic stroke and Grade 0-1 DF a (Wagner classification). The treatment group consisted of 44 patients who received rt-PA intravenous thrombolytic treatment, while 32 cases in the control group did not...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28048632/tu-d-209-03-alignment-of-the-patient-graphic-model-using-fluoroscopic-images-for-skin-dose-mapping
#9
A Oines, A Oines, J Kilian-Meneghin, B Karthikeyan, S Rudin, D Bednarek
PURPOSE: The Dose Tracking System (DTS) was developed to provide realtime feedback of skin dose and dose rate during interventional fluoroscopic procedures. A color map on a 3D graphic of the patient represents the cumulative dose distribution on the skin. Automated image correlation algorithms are described which use the fluoroscopic procedure images to align and scale the patient graphic for more accurate dose mapping. METHODS: Currently, the DTS employs manual patient graphic selection and alignment...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048097/mo-fg-campus-iep1-04-kerma-area-product-calculation-for-non-uniform-x-ray-fields-using-a-skin-dose-tracking-system
#10
S Vijayan, Z Xiong, S Rudin, D Bednarek
PURPOSE: The functionality of the Dose-Tracking System (DTS) has been expanded to include the calculation of the Kerma-Area Product (KAP) for non-uniform x-ray fields such as result from the use of compensation filters during fluoroscopic procedures METHODS: The DTS calculates skin dose during fluoroscopic interventions and provides a color-coded dose map on a patient-graphic model. The KAP is the integral of air kerma over the x-ray field and is usually measured with a transmission-ionization chamber that intercepts the entire x-ray beam...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046579/tu-d-209-02-a-backscatter-point-spread-function-for-entrance-skin-dose-determination
#11
S Vijayan, Z Xiong, A Shankar, S Rudin, D Bednarek
PURPOSE: To determine the distribution of backscattered radiation to the skin resulting from a non-uniform distribution of primary radiation through convolution with a backscatter point spread function (PSF). METHODS: A backscatter PSF is determined using Monte Carlo simulation of a 1 mm primary beam incident on a 30 × 30 cm × 20 cm thick PMMA phantom using EGSnrc software. A primary profile is similarly obtained without the phantom and the difference from the total provides the backscatter profile...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043636/evaluation-the-virulence-of-mycobacterium-bovis-isolated-from-milk-samples-through-histopathological-study-in-laboratory-animals
#12
I M Al-Saqur, A N Al-Thwani, I M Al-Attar, M S Al-Mashhadani
INTRODUCTION: Mycobacterium bovis has a broad host range, and it is the principal agent responsible for tuberculosis (TB) in bovine, domestic and wild mammals. M. bovis also infects human, causing zoonotic TB through ingestion, inhalation and, less frequently by contact with mucous membranes and broken skin. Zoonotic TB was formerly an endemic disease, usually transmitted to man by consumption of raw cow's milk. It is indistinguishable clinically or pathologically from TB caused by M...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28038884/photoprotection-in-specific-populations-children-and-people-of-color
#13
Tania Cestari, Kesha Buster
Improved education on appropriate photoprotection in children is vital. Photoprotection for these individuals should include seeking shade, the use of physical agents (clothing, hat, sunglasses), and application of sunscreens on exposed areas. Avoidance of the use of tanning beds is an important component of education for teenagers. Ultraviolet radiation exposure induces DNA damage and photoaging in all skin types, including people of color. The extent of such damage is inversely related to constitutive skin pigmentation...
December 23, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28036304/a-mathematical-analysis-for-abcd-criteria-diagnosing-malignant-melanoma
#14
Hyunju Lee, Kiwoon Kwon
The medical community currently employs the ABCD (Asymmetry, Border irregularity, Color variegation, and Diameter of the lesion) criteria in the early diagnosis of a malignant melanoma. Although many image segmentation and classification methods are used to analyze the ABCD criteria, it is rare to see a study containing mathematical justification of the parameters that are used to quantify the ABCD criteria. In this paper, we suggest new parameters to assess Asymmetry, Border irregularity, and Color variegation and explain the mathematical meaning of the parameters...
December 30, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28035649/melanoma-perception-in-people-of-color-a-targeted-educational-intervention
#15
Lucy X Chao, Stavonnie S L Patterson, Alfred W Rademaker, Dachao Liu, Roopal V Kundu
BACKGROUND: Although melanoma is more common in non-Hispanic Whites, ethnic minorities face a greater risk of melanoma-related mortality, which may be partially attributed to presentation at atypical sites and a lack of awareness. OBJECTIVE: Our objective was to assess the effectiveness of a melanoma educational intervention targeted towards people of color. DESIGN: Participants received one of two scripted melanoma educational interventions in the summer of 2015...
December 29, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28031546/sunlight-exposure-and-vitamin-d-status-in-breastfed-infants
#16
Pinky Meena, Aashima Dabas, Dheeraj Shah, Rajeev Kumar Malhotra, S V Madhu, Piyush Gupta
OBJECTIVE: To correlate the sunlight exposure in first 6 months to vitamin D status at 6 months of age in predominantly breastfed infants; and to quantify the sunlight exposure required to achieve serum 25(OH)D level > 20 ng/mL, by 6 months of age. DESIGN: Prospective cohort. SETTING: Tertiary care hospital predominantly catering to urban poor population in Delhi. PARTICIPANTS: 132 healthy infants, delivered at term, and predominantly breastfed were enrolled at 6-8 weeks of age...
December 5, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/28030792/genomic-expression-differences-between-cutaneous-cells-from-red-hair-color-individuals-and-black-hair-color-individuals-based-on-bioinformatic-analysis
#17
Joan Anton Puig-Butille, Pol Gimenez-Xavier, Alessia Visconti, Jérémie Nsengimana, Francisco Garcia-García, Gemma Tell-Marti, Maria José Escamez, Julia Newton-Bishop, Veronique Bataille, Marcela Del Río, Joaquín Dopazo, Mario Falchi, Susana Puig
The MC1R gene plays a crucial role in pigmentation synthesis. Loss-of-function MC1R variants, which impair protein function, are associated with red hair color (RHC) phenotype and increased skin cancer risk. Cultured cutaneous cells bearing loss-of-function MC1R variants show a distinct gene expression profile compared to wild-type MC1R cultured cutaneous cells. We analysed the gene signature associated with RHC co-cultured melanocytes and keratinocytes by Protein-Protein interaction (PPI) network analysis to identify genes related with non-functional MC1R variants...
December 24, 2016: Oncotarget
https://www.readbyqxmd.com/read/28028453/identification-and-characterization-of-daldinia-eschscholtzii-isolated-from-skin-scrapings-nails-and-blood
#18
Kee Peng Ng, Chai Ling Chan, Su Mei Yew, Siok Koon Yeo, Yue Fen Toh, Hong Keat Looi, Shiang Ling Na, Kok Wei Lee, Wai-Yan Yee, Chee Sian Kuan
BACKGROUND: Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. METHODS: The nine isolates were identified based on colony morphology, light microscopy, and internal transcribed spacer (ITS)-based phylogeny. In vitro antifungal susceptibility of the fungal isolates was evaluated by the Etest to determine the minimum inhibitory concentration (MIC)...
2016: PeerJ
https://www.readbyqxmd.com/read/28028095/behavioral-responses-of-drosophila-suzukii-diptera-drosophilidae-to-visual-stimuli-under-laboratory-semifield-and-field-conditions
#19
Kevin B Rice, Brent D Short, Sharon K Jones, Tracy C Leskey
Drosophila suzukii Matsumura (Diptera: Drosophilidae) is an invasive pest in North America and Europe that attacks soft-skinned ripening fruit such as raspberries, blackberries, and blueberries. Little is known regarding the specific cues D. suzukii utilizes to locate and select host fruit, and inconsistencies in trap performance indicate the need for the development of improved monitoring and management techniques for this insect. Our studies focused on identifying attractive visual cues for adult D. suzukii and incorporating these cues into a potential attract-and-kill tactic for D...
December 2016: Environmental Entomology
https://www.readbyqxmd.com/read/28019642/recent-updates-on-melanocyte-biology-and-the-use-of-promising-bioactive-compounds-for-the-treatment-of-hypopigmentary-disorders-a-review
#20
Sharique A Ali, Ishrat Naaz, Kamal Uddin Zaidi, Ayesha Sharique Ali
Skin pigmentation is a broadly appearing phenomenon in nature which plays an important task of determining the appearance and biology of all vertebrates including human beings. Skin color is a crucial attribute, determined by the synthesis of melanin pigment within melanocytes by the process of melanogenesis and is regulated by many extrinsic as well as intrinsic factors. Tyrosinase catalyzes the key step of melanogenesis, dysfunction of tyrosinase leads to reduce melanin production which results in severe clinical and aesthetical problems of hypopigmentation...
December 23, 2016: Mini Reviews in Medicinal Chemistry
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