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Nonmelanoma

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https://www.readbyqxmd.com/read/29786848/annual-report-to-the-nation-on-the-status-of-cancer-part-i-national-cancer-statistics
#1
Kathleen A Cronin, Andrew J Lake, Susan Scott, Recinda L Sherman, Anne-Michelle Noone, Nadia Howlader, S Jane Henley, Robert N Anderson, Albert U Firth, Jiemin Ma, Betsy A Kohler, Ahmedin Jemal
BACKGROUND: The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) collaborate to provide annual updates on cancer occurrence and trends in the United States. METHODS: Incidence data were obtained from the CDC-funded and NCI-funded population-based cancer registry programs and compiled by NAACCR. Data on cancer deaths were obtained from the National Center for Health Statistics National Vital Statistics System...
May 22, 2018: Cancer
https://www.readbyqxmd.com/read/29785825/pembrolizumab-treatment-of-a-patient-with-xeroderma-pigmentosum-with-disseminated-melanoma-and-multiple-nonmelanoma-skin-cancers
#2
K H Kraemer, D Tamura, S G Khan
No abstract text is available yet for this article.
May 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29752800/raman-biophysical-markers-in-skin-cancer-diagnosis
#3
Xu Feng, Austin J Moy, Hieu T M Nguyen, Yao Zhang, Jason Zhang, Matthew C Fox, Katherine R Sebastian, Jason S Reichenberg, Mia K Markey, James W Tunnell
Raman spectroscopy (RS) has demonstrated great potential for in vivo cancer screening; however, the biophysical changes that occur for specific diagnoses remain unclear. We recently developed an inverse biophysical skin cancer model to address this issue. Here, we presented the first demonstration of in vivo melanoma and nonmelanoma skin cancer (NMSC) detection based on this model. We fit the model to our previous clinical dataset and extracted the concentration of eight Raman active components in 100 lesions in 65 patients diagnosed with malignant melanoma (MM), dysplastic nevi (DN), basal cell carcinoma, squamous cell carcinoma, and actinic keratosis...
May 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29746428/review-of-nonmelanoma-skin-cancer-in-african-americans-hispanics-and-asians
#4
Shauna Higgins, Azadeh Nazemi, Maggie Chow, Ashley Wysong
BACKGROUND: Skin cancer has traditionally been studied in Caucasian skin. Although it does occur with increased relative frequency in Caucasians, patients with skin of color suffer from elevated morbidity and mortality when diagnosed with skin cancer. OBJECTIVE: To detail the unique demographic and clinical features of nonmelanoma skin cancer (NMSC) in patients with skin of color, including Hispanic, African American, and Asian patients. MATERIALS AND METHODS: A complete PubMed search was conducted spanning dates from 1947 to June 2017 yielding a total of 185 manuscripts, from which 45 were included in this review...
May 9, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29746279/free-style-capillary-perforator-based-island-flaps-for-reconstruction-of-skin-cancer-defects-of-the-face-body-and-extremities
#5
Giuseppe Visconti, Marzia Salgarello
BACKGROUND: The perforator flap concept has revolutionized reconstructive surgery. Recently, the attention has moved toward flaps based on capillary perforators, which have been usually neglected in the past as reliable perforators. The aim of this article is to report a series of freestyle capillary perforator-based island flap (c-PBIF) for reconstruction of skin cancer defects of the face, body, and extremities. PATIENTS AND METHODS: Between September 2015 and July 2017, 20 consecutive patients underwent c-PBIF reconstruction of facial, body, and limb defects after melanoma and nonmelanoma skin cancer excision...
April 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29742179/demographic-and-tumor-characteristics-of-patients-younger-than-50-years-with-nonmelanoma-skin-cancer-referred-for-mohs-micrographic-surgery
#6
Nicola A Quatrano, Euphemia W Mu, David E Orbuch, Adele Haimovic, Roy G Geronemus, Jeremy A Brauer
BACKGROUND: An increase in nonmelanoma skin cancer (NMSC) in younger patients has been reported. Many are treated with Mohs micrographic surgery (MMS). OBJECTIVE: Investigate patient and tumor characteristics in patients less than 50 years undergoing MMS for NMSC at a large, referral-based practice. METHODS & MATERIALS: Retrospective chart review of 1,332 tumors occurring in 1,018 consecutive patients over a five-year period. RESULTS: 81...
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29710082/accuracy-of-skin-cancer-diagnosis-by-physician-assistants-compared-with-dermatologists-in-a-large-health-care-system
#7
Alyce M Anderson, Martha Matsumoto, Melissa I Saul, Aaron M Secrest, Laura K Ferris
Importance: Physician assistants (PAs) are increasingly used in dermatology practices to diagnose skin cancers, although, to date, their diagnostic accuracy compared with board-certified dermatologists has not been well studied. Objective: To compare diagnostic accuracy for skin cancer of PAs with that of dermatologists. Design, Setting, and Participants: Medical record review of 33 647 skin cancer screening examinations in 20 270 unique patients who underwent screening at University of Pittsburgh Medical Center-affiliated dermatology offices from January 1, 2011, to December 31, 2015...
April 18, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29701018/advances-in-optical-coherence-tomography-in-dermatology-a-review
#8
Jonas Olsen, Jon Holmes, Gregor B Jemec
Optical coherence tomography (OCT) was introduced as an imaging system, but like ultrasonography, other measures, such as blood perfusion and polarization of light, have enabled the technology to approach clinical utility. This review aims at providing an overview of the advances in clinical research based on the improving technical aspects. OCT provides cross-sectional and en face images down to skin depths of 0.4 to 2.00 mm with optical resolution of 3 to 15  μm. Dynamic optical coherence tomography (D-OCT) enables the visualization of cutaneous microvasculature via detection of rapid changes in the interferometric signal of blood flow...
April 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29698213/what-do-germans-want-to-know-about-skin-cancer-a-nationwide-google-search-analysis-from-2013-to-2017
#9
Stefanie Seidl, Barbara Schuster, Melvin Rüth, Tilo Biedermann, Alexander Zink
BACKGROUND: Experts worldwide agree that skin cancer is a global health issue, but only a few studies have reported on world populations' interest in skin cancer. Internet search data can reflect the interest of a population in different topics and thereby identify what the population wants to know. OBJECTIVE: Our aim was to assess the interest of the German population in nonmelanoma skin cancer (NMSC) and melanoma. METHODS: Google AdWords Keyword Planner was used to identify search terms related to NMSC and melanoma in Germany from November 2013 to October 2017...
April 13, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29684233/secondary-prevention-strategies-for-nonmelanoma-skin-cancer
#10
REVIEW
Adriana T Lopez, Richard D Carvajal, Larisa Geskin
Skin cancer is the most commonly diagnosed cancer in the United States and has become a major public health problem that continues to grow. Despite numerous initiatives and increased public awareness of the dangers of skin cancer, the incidence of skin cancer continues to rise worldwide. This highlights the need for a critical review of existing skin cancer prevention strategies as a means to determine where targeted efforts may improve patient outcomes. In this article, we review the published literature and evaluate secondary prevention strategies for nonmelanoma skin cancer...
April 15, 2018: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/29661854/targeting-toll-like-receptors-in-cancer-prevention
#11
EDITORIAL
Karen S Sfanos
There is a pressing need for the development of new prevention strategies for the most common worldwide malignancy, nonmelanoma skin cancer (NMSC), as sun protection efforts have not proven to be completely effective. Interestingly, despite the known circumstance that individuals undergoing chronic immunosuppression are at a substantially increased risk for developing NMSC, in this issue of Cancer Prevention Research , Blohm-Mangone and colleagues provide new evidence that topical application of the Toll-like receptor 4 (TLR4) antagonist resatorvid may be efficacious as a chemopreventive agent in NMSC specifically via blocking UV-induced inflammatory signaling...
April 16, 2018: Cancer Prevention Research
https://www.readbyqxmd.com/read/29648613/trending-on-pinterest-an-examination-of-pins-about-skin-tanning
#12
Smita C Banerjee, Vivian M Rodríguez, Kathryn Greene, Jennifer L Hay
Rates of melanoma and nonmelanoma skin cancers are on the rise in the USA with data revealing disproportionate increase in female young adults. The popularity of intentional skin tanning among U.S. adolescents is attributed to several factors, including prioritization of physical appearance, media images of tanned celebrities, ease of availability of artificial tanning facilities, and more recently, the prevalence and celebration of tanned skin on social media. Pinterest, as the third most popular social media platform, was searched for "pins" about skin tanning...
April 10, 2018: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/29622273/fr-risk-of-nonmelanoma-skin-cancer-in-patients-on-hemodialysis
#13
P Aguayo Carreras, J Tercedor Sánchez, R Ruiz Villaverde
No abstract text is available yet for this article.
April 2, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29596618/patterns-in-health-care-access-and-affordability-among-cancer-survivors-during-implementation-of-the-affordable-care-act
#14
Ryan D Nipp, Amy M Shui, Giselle K Perez, Anne C Kirchhoff, Jeffrey M Peppercorn, Beverly Moy, Karen Kuhlthau, Elyse R Park
Importance: Cancer survivors face ongoing health issues and need access to affordable health care, yet studies examining health care access and affordability in this population are lacking. Objectives: To evaluate health care access and affordability in a national sample of cancer survivors compared with adults without cancer and to evaluate temporal trends during implementation of the Affordable Care Act. Design, Setting, and Participants: We used data from the National Health Interview Survey from 2010 through 2016 to conduct a population-based study of 30 364 participants aged 18 years or older...
March 29, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29594182/model-based-quantitative-optical-biopsy-in-multilayer-in-vitro-soft-tissue-models-for-whole-field-assessment-of-nonmelanoma-skin-cancer
#15
Bala Nivetha Kanakaraj, Sujatha Narayanan Unni
Optical techniques such as fluorescence and diffuse reflectance spectroscopy are proven to have the potential to provide tissue discrimination during the development of malignancies and hence treated as potential tools for noninvasive optical biopsy in clinical diagnostics. Quantitative optical biopsy is challenging and hence the majority of the existing strategies are based on a qualitative assessment of the concerned tissue. Light-tissue interaction models as well as precise optical phantoms can greatly help in the former and here we present a pilot study to assess the optical properties of a multilayer tissue-specific optical phantom with the help of a database generated using multilayer-Monte Carlo (MCML) models...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29579884/prevalence-and-survival-of-cancer-after-pancreas-kidney-transplantation
#16
M V Pendón-Ruiz de Mier, M L Agüera, M D Navarro, A Rodriguez-Benot, P Aljama
BACKGROUND: Malignancy is an important cause of mortality in solid organ transplantation. There have been few studies of de novo solid organ malignancy (NSOM) after pancreas-kidney transplantation (PKT). The aim of this study was analyze the prevalence of NSOM and transplant outcomes. METHODS: We studied the development of NSOM after PKT in our center from May 1990 to February 2017. We analyzed demographic characteristics, prevalence of cancer, and survival after cancer diagnosis...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29577672/cancer-risk-in-patients-with-alopecia-areata-a-nationwide-population-based-matched-cohort-study
#17
Chih-Chiang Chen, Yun-Ting Chang, Han-Nan Liu, Yi-Ju Chen
Alopecia areata (AA) is an organ-specific autoimmune disorder. Defective immune system related disorders are prone to increase the risk of cancer formation. However, the association among AA and variety of cancer types had never been studied. A nationwide population-based matched cohort study was conducted to evaluate the cancer risk in patients with AA. Records from Taiwan National Health Insurance Research Database were analyzed. Cases of AA from 1997 to 2013 and cancers registered in the catastrophic illness profile from the same time period were collected...
March 25, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29570823/a-pediatric-case-of-squamous-cell-cancer-in-situ-in-the-setting-of-sclerodermatous-graft-versus-host-disease-and-voriconazole-treatment
#18
Alvin W Li, Leah E Lalor, Fernanda Bellodi Schmidt, Minnelly Luu
Sclerodermatous graft-versus-host disease is a subtype of cutaneous chronic graft-versus-host disease that is characterized by sclerosis of the skin and subcutaneous tissue, resulting in debilitating contractures, among other life-threatening complications. Children with sclerodermatous graft-versus-host disease are at high risk of developing nonmelanoma skin cancer because of several risk factors, including young age at transplantation, prolonged immunosuppression, and exposure to photosensitizing antimicrobial prophylaxis such as voriconazole...
March 23, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29566922/nonsurgical-treatment-of-nonmelanoma-skin-cancer-in-the-mature-patient
#19
Romana Čeović, Mikela Petković, Zrinka Bukvić Mokos, Krešimir Kostović
Nonmelanoma skin cancer (NMSC) is the most common cancer, with the median age at NMSC diagnosis is 71 years. Treatment options for NMSC include surgical therapy, which is usually the first-choice treatment, and nonsurgical modalities. Therapeutic modalities depend on tumor localization, histologic type, and biologic behavior, as well as patient comorbidities, age, and life expectancy. Nonsurgical treatments include cryotherapy, local therapies (imiquimod, 5-fluorouracil, ingenol mebutate, and diclofenac), photodynamic therapy, radiotherapy, and hedgehog inhibitors...
March 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29559812/a-cohort-study-on-the-risk-of-lymphoma-and-skin-cancer-in-users-of-topical-tacrolimus-pimecrolimus-and-corticosteroids-joint-european-longitudinal-lymphoma-and-skin-cancer-evaluation-joelle-study
#20
Jordi Castellsague, Josephina G Kuiper, Anton Pottegård, Ingegärd Anveden Berglind, Daniel Dedman, Lia Gutierrez, Brian Calingaert, Myrthe Pp van Herk-Sukel, Jesper Hallas, Anders Sundström, Arlene M Gallagher, James A Kaye, Carolina Pardo, Kenneth J Rothman, Susana Perez-Gutthann
Background: There is a concern that topical tacrolimus and pimecrolimus, indicated for second-line treatment of atopic dermatitis, may increase the risk of lymphoma and skin cancer, particularly in children. Objective: The aim of this study was to compare incidence rates (IRs) of lymphoma and skin cancer between new users of topical tacrolimus or pimecrolimus and users of moderate- to high-potency topical corticosteroids (TCSs) and untreated subjects. Methods: This is a multicenter cohort study with frequency matching by strata of propensity scores in population databases in the Netherlands, Denmark, Sweden, and the UK...
2018: Clinical Epidemiology
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