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Whole-body mri

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https://www.readbyqxmd.com/read/28095379/diffusion-tensor-imaging-detects-occult-cerebellar-injury-in-severe-neonatal-hypoxic-ischemic-encephalopathy
#1
Monica E Lemmon, Matthias W Wagner, Thangamadhan Bosemani, Kathryn A Carson, Frances J Northington, Thierry A G M Huisman, Andrea Poretti
BACKGROUND: Despite the benefits of whole-body hypothermia therapy, many infants with hypoxic-ischemic encephalopathy (HIE) die or have significant long-term neurodevelopmental impairment. Prospectively identifying neonates at risk of poor outcome is essential but not straightforward. The cerebellum is not classically considered to be a brain region vulnerable to hypoxic-ischemic insults; recent literature suggests, however, that the cerebellum may be involved in neonatal HIE. In this study, we aimed to assess the microstructural integrity of cerebellar and linked supratentorial structures in neonates with HIE compared to neurologically healthy neonatal controls...
January 18, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28091804/baseline-results-from-the-uk-signify-study-a-whole-body-mri-screening-study-in-tp53-mutation-carriers-and-matched-controls
#2
Sibel Saya, Emma Killick, Sarah Thomas, Natalie Taylor, Elizabeth K Bancroft, Jeanette Rothwell, Sarah Benafif, Alexander Dias, Christos Mikropoulos, Jenny Pope, Anthony Chamberlain, Ranga Gunapala, Louise Izatt, Lucy Side, Lisa Walker, Susan Tomkins, Jackie Cook, Julian Barwell, Vicki Wiles, Lauren Limb, Diana Eccles, Martin O Leach, Susan Shanley, Fiona J Gilbert, Helen Hanson, David Gallagher, Bala Rajashanker, Richard W Whitehouse, Dow-Mu Koh, S Aslam Sohaib, D Gareth Evans, Rosalind A Eeles
In the United Kingdom, current screening guidelines for TP53 germline mutation carriers solely recommends annual breast MRI, despite the wide spectrum of malignancies typically seen in this group. This study sought to investigate the role of one-off non-contrast whole-body MRI (WB MRI) in the screening of asymptomatic TP53 mutation carriers. 44 TP53 mutation carriers and 44 population controls were recruited. Scans were read by radiologists blinded to participant carrier status. The incidence of malignancies diagnosed in TP53 mutation carriers against general population controls was calculated...
January 16, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28090448/quantitative-techniques-for-musculoskeletal-mri-at-7-tesla
#3
REVIEW
Neal K Bangerter, Meredith D Taylor, Grayson J Tarbox, Antony J Palmer, Daniel J Park
Whole-body 7 Tesla MRI scanners have been approved solely for research since they appeared on the market over 10 years ago, but may soon be approved for selected clinical neurological and musculoskeletal applications in both the EU and the United States. There has been considerable research work on musculoskeletal applications at 7 Tesla over the past decade, including techniques for ultra-high resolution morphological imaging, 3D T2 and T2* mapping, ultra-short TE applications, diffusion tensor imaging of cartilage, and several techniques for assessing proteoglycan content in cartilage...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28090444/bone-marrow-edema-like-lesions-bmels-are-associated-with-higher-t1%C3%AF-and-t2-values-of-cartilage-in-anterior-cruciate-ligament-acl-reconstructed-knees-a-longitudinal-study
#4
Jingshan Gong, Valentina Pedoia, Luca Facchetti, Thomas M Link, C Benjamin Ma, Xiaojuan Li
BACKGROUND: To evaluate the longitudinal changes of bone marrow edema-like lesions (BMELs) in patients after anterior cruciate ligament (ACL) reconstruction and to investigate the effect of BMELs on cartilage matrix composition changes measured using MR T1ρ and T2 mapping. METHODS: Patients with acute ACL tear were enrolled in a prospective study. MR imaging was performed at baseline (before surgeries) and at 6-month, 1-year and 2-year after ACL reconstruction...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28088340/the-role-of-magnetic-resonance-imaging-techniques-in-evaluation-and-management-of-the-idiopathic-inflammatory-myopathies
#5
REVIEW
Jessica Day, Sandy Patel, Vidya Limaye
Magnetic resonance imaging (MRI) is an important tool in the evaluation of neuromuscular disorders. MRI accurately demonstrates muscle oedema, atrophy, subcutaneous pathology and fatty infiltration and also highlights the distribution of muscle involvement. This review examines the role of MRI in evaluation of the idiopathic inflammatory myopathies (IIMs), a heterogeneous group of autoimmune conditions characterised by muscle inflammation and a variety of extra-muscular manifestations. MRI has a clear role in aiding diagnosis of these conditions, guiding muscle biopsy, differentiating subtypes of IIM using a pattern-based approach, and monitoring disease activity in a longitudinal fashion...
November 5, 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28062546/the-clinical-importance-of-quantifying-fat-distribution-during-androgen-deprivation
#6
Stephen John Foulkes, Robin M Daly, Steve Fraser
Androgen deprivation therapy (ADT) is now considered a mainstay in the treatment of metastatic and locally advanced prostate cancer (PCa). Despite well-established benefits of ADT in relation to overall survival, this treatment has been associated with a number of adverse effects, particularly with regard to key cardiometabolic risk factors including the development of insulin resistance, dyslipidaemia and increases in total and regional fat mass. In non-ADT populations, increased levels of visceral adipose tissue (VAT) are thought to be a key mediator of the increased cardiometabolic risk associated with weight gain, but this has received limited attention in men treated with ADT...
January 6, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28060123/whole-body-mri-virtual-autopsy-using-diffusion-weighted-imaging-with-background-suppression-dwibs-at-3-t-in-a-child-succumbing-to-chordoma
#7
Savvas Andronikou, Marnie L Kemp, Michelle Meiring
BACKGROUND: We report the use of diffusion-weighted imaging with background suppression (DWIBS) in pediatric virtual magnetic resonance imaging (MRI) autopsy of a child who succumbed to chordoma. CASE DESCRIPTION: A 10-year-old girl who succumbed to relapse of a chordoma underwent whole-body virtual MRI autopsy 12 hours postmortem with short Tau inversion recovery (STIR) and DWIBS on 3 T, which demonstrated the primary mass, local and cardiac invasion, and metastatic disease to the thorax, abdomen, head/neck, and musculoskeletal system...
January 5, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28048696/mo-fg-campus-iep3-01-evaluation-of-specific-absorption-rate-and-temperature-increase-induced-by-artificial-medical-implants-during-mri-scan
#8
Y Seo
PURPOSE: Heating of patients or burning of biological tissues around medical implants by RF power during MRI scan is a significant patient safety concern. The purpose of this study is to not only measure SAR values, but also RF-induced temperature elevation due to artificial hip joints during MRI scans. METHODS: SAR measurement experiment was performed on three discrete manufacturers at 1.5 and 3T. Three MRI RF sequences (T1w TSE, T2w inversion recovery, and T2w TSE) with imaging parameters were selected...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048528/we-h-206-01-photoacoustic-tomography-multiscale-imaging-from-organelles-to-patients-by-ultrasonically-beating-the-optical-diffusion-limit
#9
L Wang
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048364/we-fg-207a-01-introduction-to-dedicated-breast-ct-early-studies
#10
S Vedantham
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048323/su-d-207a-05-investigating-sparse-sampled-mri-for-motion-management-in-thoracic-radiotherapy
#11
P Sabouri, T Arai, A Sawant
PURPOSE: Sparse sampling and reconstruction-based MRI techniques represent an attractive strategy to achieve sufficiently high image acquisition speed while maintaining image quality for the task of radiotherapy guidance. In this study, we examine rapid dynamic MRI using a sparse sampling sequence k-t BLAST in capturing motion-induced, cycle-to-cycle variations in tumor position. We investigate the utility of long-term MRI-based motion monitoring as a means of better characterizing respiration-induced tumor motion compared to a single-cycle 4DCT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048035/mo-fg-campus-iep3-02-gradient-nonlinearity-calibration-and-correction-for-full-volume-imaging-of-a-compact-asymmetric-mri-gradient-system
#12
S Tao, J Trzasko, Y Shu, P Weavers, J Gunter, J Huston, S Lee, E Tan, M Bernstein
PURPOSE: Due to engineering limitations, the spatial encoding gradient fields generated by an MRI scanner are inherently nonlinear and images must undergo geometric correction prior to display. The gradient nonlinearity (GNL) of a conventional symmetric whole-body gradient is typically characterized using a spherical harmonic polynomial (SHP) expansion of magnetic gradient fields with up to fifth-order terms. Only odd-order terms are required due to design symmetry (i.e., 3rd/5th-order)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047869/we-h-206-02-recent-advances-in-multi-modality-molecular-imaging-of-small-animals
#13
B Tsui
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047717/we-fg-207a-02-why-we-need-breast-ct-clinical-perspective
#14
A O'Connell
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047652/su-f-sps-07-magnetic-resonance-spectroscopy-findings-in-early-phase-psychosis
#15
A Wright, R Ma, T Hummer, M Francis, N Mehdiyoun, U Dydak, A Breier
PURPOSE: Schizophrenia is a psychiatric disorder characterized by disordered thoughts, abnormal social behaviors, flat affect, and auditory or visual hallucinations. The current study aims to investigate alterations in brain metabolism in patients near the onset of psychosis (early-phase psychosis, EPP), to characterize abnormalities during the early stages of schizophrenia. To this end, we used magnetic resonance imaging (MRI) and spectroscopy (MRS) to measure metabolite levels and subsequently monitor the effect of treatment with N-acetylcysteine (NAC)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047587/th-cd-207a-01-evaluation-of-lung-tumor-motion-management-strategy-with-dynamic-mri
#16
R Farah, S Park, S Shea, E Tryggestad, J Wong, R Hales, J Lee
PURPOSE: The purpose of this study is to develop a method to track and examine the correlation between the 3D motion of a lung tumor and an external surrogate with dynamic MRI. METHODS: Dynamic MRI was obtained from lung cancer patients. To examine the motion correlation between external surrogates and the tumor, we placed four fiducials on the patient's chest at different locations. We acquired a contiguous multi-slice 2D cine MRI (sagittal) to capture the lung and whole tumor, followed by a two-slice 2D cine MRI (sagittal) to simultaneously track the tumor and fiducials...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047520/we-fg-207a-05-dedicated-breast-ct-as-a-diagnostic-imaging-tool-physics-and-clinical-feasibility
#17
A Karellas
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047507/su-f-i-27-measurement-of-sar-and-temperature-elevation-during-mri-scans
#18
Y Seo
PURPOSE: The poor reliability and repeatability of the manufacturer-reported SAR values on clinical MRI systems have been acknowledged. The purpose of this study is to not only measure SAR values, but also RF-induced temperature elevation at 1.5 and 3T MRI systems. METHODS: SAR measurement experiment was performed at 1.5 and 3T. Three MRI RF sequences (T1w TSE, T1w inversion recovery, and T2w TSE) with imaging parameters were selected. A hydroxyl-ethylcelluose (HEC) gelled saline phantom mimicking human body tissue was made...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047205/we-h-206-03-promises-and-challenges-of-benchtop-x-ray-fluorescence-ct-xfct-for-quantitative-in-vivo-imaging
#19
S Cho
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047068/we-fg-207a-03-low-dose-cone-beam-breast-ct-physics-and-technology-development
#20
J Boone
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
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