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https://www.readbyqxmd.com/read/28937919/neurosurgical-management-of-a-rare-congenital-supratentorial-neurenteric-cyst-with-associated-nasal-dermal-sinus-case-report
#1
Paul MacMahon, Stanca Iacob, Sarah E Bach, Eric T Elwood, Julian J Lin, Anthony M Avellino
The authors describe the case of a patient with the classic clinical presentation and radiographic features of a nasal dermal sinus with an associated intracranial cyst; however, histopathology revealed that the intracranial cyst was neurenteric instead of the typical epidermoid or dermoid cyst. Preoperative assessment included CT and MRI, which revealed a direct communication between the patient's nasal polypoid lesion and the anterior skull base via the foramen cecum. At the hands of a multidisciplinary plastic surgery and neurosurgery team, the patient underwent concurrent gross-total resection of the nasal polypoid lesion, the intracranial intradural cystic lesion, and their interconnecting tract...
September 15, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28932376/pulmonary-nodules-in-a-patient-with-rheumatoid-arthritis-which-diagnostic-approach-is-the-most-appropriate
#2
Ines Mahmoud, Aicha Ben Tekaya, Rawdha Tekaya, Olfa Saidane, Leila Gafsi, Mathilde Benhammou, Fautrel Bruno, Leila Abdelmoula
BACKGROUND: Pulmonary nodular excavation should firstly evoke tuberculosis or necrosis broncho-pulmonary tumor, particularly: epidermoid carcinoma. The case discussed here illustrated these difficulties in patients with rheumatoid arthritis (RA). CASE PRESENTATION: A 63-year-old woman was presented with a-three-year history of RA and a recent discovery of an excavated pulmonary nodule. Initial investigations focused on a rheumatoid origin. The evolution of the disease was worrisome and surgical exploration was deemed mandatory...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28932061/epidermal-cysts-a-clinicopathological-analysis-with-emphasis-on-unusual-findings
#3
Jitendra Singh Nigam, Jyotsna Naresh Bharti, Vivek Nair, Chitrawati Bal Gargade, Archana Hemant Deshpande, Biswajit Dey, Ashok Singh
BACKGROUND: Epidermoid cysts, one of the common benign intradermal or subcutaneous tumors commonly result from the trauma to the pilosebaceous unit in the hair bearing area. In areas without hair, these cysts are considered implantation and proliferation of squamous epithelium into the dermis due to injury. AIMS: The aim is to evaluate the clinicopathological details with emphasis on unusual findings related to epidermoid cysts. STUDY DESIGN: This is a retrospective cross-sectional study carried out over 2 years...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28924550/establishment-and-characterization-of-arsenic-trioxide-resistant-kb-ato-cells
#4
Yun-Kai Zhang, Chunling Dai, Chun-Gang Yuan, Hsiang-Chun Wu, Zhijie Xiao, Zi-Ning Lei, Dong-Hua Yang, X Chris Le, Liwu Fu, Zhe-Sheng Chen
Arsenic trioxide (ATO) is used as a chemotherapeutic agent for the treatment of acute promyelocytic leukemia. However, increasing drug resistance is reducing its efficacy. Therefore, a better understanding of ATO resistance mechanism is required. In this study, we established an ATO-resistant human epidermoid carcinoma cell line, KB/ATO, from its parental KB-3-1 cells. In addition to ATO, KB/ATO cells also exhibited cross-resistance to other anticancer drugs such as cisplatin, antimony potassium tartrate, and 6-mercaptopurine...
September 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28923322/cycloartane-type-triterpene-glycosides-anopanins-a-c-with-monoacyldigalactosylglycerols-from-anodendron-paniculatum
#5
Viet Duc Ho, Thi Nhu Hanh Hoang, Quoc Hung Vo, Van Kiem Phan, Tuan Anh Le, Viet Ty Pham, Minh Hien Nguyen, Takeshi Kodama, Takuya Ito, Hiroyuki Morita, Ain Raal, Thi Hoai Nguyen
Three cycloartane-type triterpene glycosides (anopanins A-C), together with three known monoacyldigalactosylglycerols gingerglycolipids A-C and (2S)-1-O-palmitoyl-3-O-[α-d-galactopyranosyl-(1→6)-β-d-galactopyranosyl]-sn-glycerol, were isolated from the aerial parts of Anodendron paniculatum collected in Viet Nam. The chemical structures of the present compounds were elucidated by means of 1D and 2D NMR and HRESIMS spectroscopy, and by comparing to the reported data in the literature. These compounds did not show significant growth inhibitory activities (IC50 > 100 μg/mL) against the tested cancer cell lines LU-1 (lung adenocarcinoma), KB (epidermoid carcinoma), Hep-G2 (hepatoma cancer), MKN-7 (stomach cancer), and SW-480 (colon adenocarcinoma)...
September 15, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28914873/-the-extended-endoscopic-endonasal-transsphenoidal-approach-in-surgery-for-epidermoid-cysts-of-the-chiasmatic-region
#6
D V Fomichev, P L Kalinin, M A Kutin, O I Sharipov, I V Chernov
Surgical treatment for epidermoid cysts of the chiasmatic region is a challenge because of the tendency to a massive spread of epidermoid masses through the cerebrospinal fluid pathways and a significant lesion deviation from the midline. PURPOSE: To analyze capabilities of the extended endoscopic endonasal transsphenoidal approach in surgery for epidermoid cysts. MATERIAL AND METHODS: The study included 6 patients with epidermoid cysts of the chiasmatic region who were operated on using the extended anterior endoscopic endonasal transsphenoidal approach at the Burdenko Neurosurgical Institute in the past 5 years...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28899831/acquired-chiari-i-malformation-with-syringomyelia-secondary-to-colloid-cyst-with-hydrocephalus-case-report-and-review-of-literature
#7
Amit Kumar Thotakura, Nageswara R Marabathina
INTRODUCTION: Acquired Chiari malformation and associated syringomyelia have been previously described following lumbar puncture/drainage, lumboperitoneal shunts, and spontaneous CSF leakage. In addition to these etiologies, space-occupying lesions such as meningiomas, epidermoid cysts, medulloblastomas, and arachnoid cysts are rare causes of acquired Chiari malformation and syringomyelia. We report a rare case of colloid cyst with hydrocephalus causing secondary Chiari malformation with syringomyelia...
September 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28891704/mucoepidermoid-carcinoma-in-the-skull-of-an-orange-winged-amazon-parrot-amazona-amazonica
#8
Melissa R Nau, James W Carpenter, Denise Lin, Sanjeev Narayanan, Mackenzie Hallman
A 33-year-old female intact orange-winged Amazon parrot (Amazona amazonica) presented for a slowly growing mass over the right eye. A computed tomography scan performed with and without intravenous contrast revealed a heterogeneous mixed soft tissue and mineral-dense mass with a small area of non-contrast-enhancing fluid density located between the orbits at the caudal aspect of the nasal passages, with associated lysis of the right caudal nasal passage and the right frontal bone. Following euthanasia, the mass was found to consist of soft tissue between the right eye and nostril over the right frontal bone...
September 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28885435/treatment-of-metastatic-eyelid-carcinoma
#9
Paola Bonavolontà, Giovanni Dell'Aversana Orabona, Vincenzo Abbate, Giorgio Iaconetta, Giulio Bonavolontà, Luigi Califano
PURPOSE: The aim of this study was to report management and outcomes in patients affected by eyelids carcinomas involving regional lymph nodes. METHODS: We have retrospectively analyzed the data of patients affected by eyelids carcinoma with nodal involvement. The clinical records of 10 patients with malignant eyelid carcinoma and regional nodal metastasis treated between September 2011 and March 2015 have been analyzed. RESULTS: The study included 5 women and 5 men (median age 54,5 years; range 37-80 years)...
September 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28883682/role-of-mri-in-diagnosis-of-ruptured-intracranial-dermoid-cyst
#10
Sefedin Muçaj, Mehmet Sahin Ugurel, Kreshnike Dedushi, Naser Ramadani, Naim Jerliu
INTRODUCTION: Intracranial dermoid cystic tumors account for <1% of all intracranial masses. CASE REPORT: A 52-year-old male, having headaches, nausea and is presented with a history of 2 episodes of new onset seizures. On presentation, the patient had a normal physical exam, including a complete neurological and cranial nerve exam. METHODS: Precontrast MRI; TSE/T2Wsequence in axial/coronal planes; 3D - HI-resolution T1W sagittal; FLAIR/T2W axial; FLAIR/T2W, Flash/T2W oblique coronal plane, GRE/T2W axial...
June 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28880901/abo-blood-type-and-the-risk-of-cancer-findings-from-the-shanghai-cohort-study
#11
Joyce Yongxu Huang, Renwei Wang, Yu-Tang Gao, Jian-Min Yuan
ABO blood type is an inherited characteristic. The associations between ABO blood type and risk of all cancer and specific cancers were examined in a prospective cohort study of 18,244 Chinese men enrolled in 1986. During the 25 years of follow-up, 3,973 men developed cancer including 964 lung cancers, 624 colorectal cancers, 560 gastric cancers, 353 liver cancers, and 172 urinary bladder cancers. Hazard ratios (HR) for all cancer and specific cancers by ABO blood type were calculated using Cox proportional hazards models...
2017: PloS One
https://www.readbyqxmd.com/read/28880599/giant-plantar-epidermoid-cyst-with-invasion-of-the-interosseous-muscles
#12
Antonio Córdoba-Fernandez, Adrián Lobo-Martín, Carlos Escudero-Severín, Victoria Eugenia Córdoba-Jiménez
Epidermoid cysts of the sole of the foot are rare lesions that must be differentiated from other, more common subcutaneous pathologic abnormalities located on the sole. Cases of epidermoid cysts that extend to the interosseous musculature are rarer still. We report the case of a giant epidermal cyst in a 64-year-old individual that extended to the intrinsic musculature of the third space of the right foot and that was diagnosed after fine-needle aspiration biopsy and subsequent cytologic study. Differential diagnosis of these lesions should be made with the support of additional imaging tests, and diagnostic confirmation should always be obtained after surgical removal and subsequent histopathologic study...
July 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28880406/incidental-neuronal-intermediate-filament-inclusion-pathology-unexpected-biopsy-findings-in-a-37-year-old-woman-with-epilepsy
#13
Ellen Gelpi, Cristina Carrato, Laia Grau-López, Juan Luis Becerra, Roser Garcia-Armengol, Anna Massuet, Laura Cervera, Jordi Clarimon, Katrin Beyer, Ramiro Álvarez
We present unexpected neuropathological findings in a 37 year old woman who underwent surgery for removal of an epidermoid cyst. A first brain MRI at the age of 27 years (due to hyperprolactinemia) showed a cystic lesion in the right prepontine region involving the cisterna ambiens with supratentorial extension. The lesion remained stable until she was 32 year, when it increased in size causing partial compression of the parahippocampal gyrus, midbrain peduncle and lateral pons (Fig. 1). One year later, the patient started to present weekly seizures in form of partial focal complex seizures...
September 7, 2017: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/28877411/new-cytotoxic-triterpenoid-saponins-from-the-roots-of-albizia-gummifera-c-a-smith
#14
Line Made Simo, Olivier Placide Noté, Joséphine Ngo Mbing, Sarah Ali Aouazou, Dominique Guillaume, Christian Dominique Muller, Dieudonné Emmanuel Pegnyemb, Annelise Lobstein
As part of our search of new bioactive saponins from Cameroonian medicinal plants, two new oleanane-type saponins, named gummiferaosides D-E (1-2), along with one known saponin, julibroside J8 (3), were isolated from the roots of Albizia gummifera. Their structures were established on the basis of extensive 1D and 2D NMR ((1) H-, (13) C-NMR, DEPT, COSY, TOCSY, NOESY, HSQC, HSQC-TOCSY and HMBC) and HRESIMS studies, and by chemical evidence. The apoptotic effect of saponins 1-3 was evaluated on the A431 human epidermoid cancer cell...
September 6, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28871934/diffuse-palmoplantar-keratoderma-onychodystrophy-universal-hypotrichosis-and-cysts
#15
Tasleem Arif, Syed Suhail Amin, Mohammad Adil, Mohd Mohtashim
Dear Editor, Clouston syndrome, also called hidrotic ectodermal dysplasia (HED), is an autosomal dominant ectodermal dysplasia characterized by a clinical triad of onychodystrophy, generalized hypotrichosis, and palmoplantar keratoderma (1). Herein we report the case of a 24-year-old male with the distinctive clinical triad associated with multiple epidermoid cysts, which probably reflects the phenotype of Clouston syndrome. A 24-year-old male presented to our Department with diffuse thickening of the skin of his palms and soles since infancy...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28868198/malignant-squamous-cell-carcinoma-arising-in-a-previously-resected-cerebellopontine-angle-epidermoid
#16
Annika Mascarenhas, Alyssa Parsons, Caroline Smith, Cindy Molloy, Alistair Jukes
BACKGROUND: Malignant squamous cell differentiation of an epidermoid cyst can carry a significantly poor prognosis and very little is known about this entity. CASE DESCRIPTION: We present the case of a 35-year-old lady, with primary malignant squamous cell carcinoma (SCC) arising from a previously partially resected cerebellopontine angle epidermoid cyst almost 5 years after initial resection. We also review the relevant literature. CONCLUSION: The imaging findings, histopathology, and management of a malignant SCC arising from a benign epidermoid cyst are discussed with recommendation for increased surveillance and follow-up, even for classically accepted benign lesions...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28864403/clinical-outcomes-of-several-imrt-techniques-for-patients-with-head-and-neck-cancer-a-propensity-score-weighted-analysis
#17
Jean-Emmanuel Bibault, Sophie Dussart, Pascal Pommier, Magali Morelle, Marius Huguet, Pierre Boisselier, Bernard Coche-Dequeant, Marc Alfonsi, Etienne Bardet, Michel Rives, Valentin Calugaru, Enrique Chajon, Georges Noel, Hinda Mecellem, Stephanie Servagi Vernat, Lionel Perrier, Philippe Giraud
PURPOSE: The Advanced Radiotherapy Oto-Rhino-Laryngologie (ART-ORL) study (NCT02024035) was performed to prospectively evaluate the clinical and economic aspects of helical TomoTherapy and volumetric modulated arc therapy (RapidArc, Varian Medical Systems, Palo Alto, CA) for patients with head and neck cancer. METHODS AND MATERIALS: Fourteen centers participated in this prospective comparative study. Randomization was not possible based on the availability of equipment...
June 27, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28843754/thoracic-intradural-extramedullary-epidermoid-tumor-the-relevance-for-resection-of-classical-subarachnoid-space-microsurgical-anatomy-in-modern-spinal-surgery-technical-note-and-review-of-the-literature
#18
Giuseppe Mv Barbagallo, Massimiliano Maione, Giuseppe Raudino, Francesco Certo
BACKGROUND: Intradural epidermoid tumors of the spinal cord are commonly associated with spinal cord dysraphism or invasive procedures. We report the particular relationships between spinal subarachnoid compartments and a thoracic intradural-extramedullary epidermoid tumor, highlighting the relevant anatomical changes, which may influence microsurgery. METHODS: A 40 year old woman suffering from compressive myelopathy due to a thoracic epidermoid tumor extending from T3 to T4, and not associated with spina bifida, trauma, previous surgery or lumbar spinal puncture, underwent microsurgical excision...
August 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28832036/label-free-high-content-screening-using-raman-microspectroscopy-the-toxicological-response-of-different-cell-lines-to-amine-modified-polystyrene-nanoparticles-ps-nh2
#19
Esen Efeoglu, Marcus A Maher, Alan Casey, Hugh J Byrne
Nanotoxicology has become an established area of science due to growing concerns over the production and potential use of nanomaterials in a wide-range of areas from pharmaceutics to nanomedicine. Although different cytotoxicity assays have been developed and are widely used to determine the toxicity of nanomaterials, the production of multi-parametric information in a rapid and non-invasive way is still challenging, when the amount and diversity of physicochemical properties of nanomaterials are considered...
August 23, 2017: Analyst
https://www.readbyqxmd.com/read/28830738/mastoid-epidermoid-tumor-and-associated-dural-arteriovenous-fistula-with-venous-sinus-occlusion
#20
Jang W Yoon, Youssef J Hamade, Ramon Navarro, Benjamin L Brown, Larry Lundy, Rabih G Tawk
BACKGROUND: Dural arteriovenous fistula (DAVF) is an abnormal vascular connection between arterial and venous channels within dura mater. Although DAVFs have been linked to other types of intracranial tumors, this is the first case reporting the association between DAVF and an epidermoid tumor. CASE DESCRIPTION: A middle aged patient with chronic headache presented with Borden type II DAVF draining into the right transverse sigmoid junction, and was also found to have an epidermoid tumor over the right mastoid...
August 19, 2017: World Neurosurgery
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