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Skull base tumor

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https://www.readbyqxmd.com/read/28739401/a-review-of-nasal-paranasal-and-skull-base-tumors-invading-the-orbit
#1
REVIEW
Morten Jørgensen, Steffen Heegaard
Tumors that invade the orbit are uncommon. The majority are meningiomas arising from the sphenoid ridge (66 %). Others are bone and cartilage tumors arising from the surrounding bones surrounding the orbit, pituitary adenomas, and epithelial tumors arising from the paranasal sinuses and nasal cavity. Meningiomas occur more often in females, whereas epithelial tumors have a predilection for males. Meningiomas and epithelial tumors typically present in the sixth decade of life, whereas bone tumors tend to affect individuals in their third decade of life...
July 21, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28736350/antibiotic-prophylaxis-in-endoscopic-endonasal-pituitary-and-skull-base-surgery
#2
Laura Milanese, Matteo Zoli, Giacomo Sollini, Chiara Martone, Corrado Zenesini, Carmelo Sturiale, Paolo Farneti, Giorgio Frank, Ernesto Pasquini, Diego Mazzatenta
OBJECTIVE: Postoperative infection is a potentially dramatic consequence in endoscopic endonasal surgery. The aim of this study is to assess the efficacy of our intraoperative antibiotic prophylaxis, analyzing the risk factors of postoperative meningitis in our series. METHODS: Each endoscopic endonasal procedure performed since 1998 in patients with no preoperative infections and a follow-up longer than 30 days have been included and retrospectively reviewed. Antibiotic protocol consisted in single antibiotic administration of ampicillin/sulbactam 3 g or cefazolin 2 g on induction, no postoperative administrations have been performed after 2005...
July 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28731197/metastatic-gallbladder-carcinoma-in-meningioma-a-case-report
#3
Burak Eren, Feyza Karagoz Guzey, Ilker Gulec, Azmi Tufan
Metastases from tumors to systemic cancers are rare. The most common intracranial recipient tumor is meningioma. Metastasis from gallbladder cancer has been previously reported from only one patient during autopsy. We present the case of a 72-year-old woman who underwent surgery for right frontal skull base meningioma.The tumor was completely removed. Histological specimens showed gallbladder carcinomatous metastasis with diffuse neuroendocrine differentiation in meningothelial meningioma. The Ki-67 proliferation index of the meningioma was 3%...
June 2, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28729769/recurrence-and-cancerization-of-ameloblastoma-multivariate-analysis-of-87-recurrent-craniofacial-ameloblastoma-to-assess-risk-factors-associated-with-early-recurrence-and-secondary-ameloblastic-carcinoma
#4
Rong Yang, Zheqi Liu, Sandhya Gokavarapu, Canbang Peng, Tong Ji, Wei Cao
OBJECTIVE: The recurrence and progression of ameloblastoma are unpredictable. Therefore, we examined the influence of clinical factors on recurrence time and analyzed the clinical factors associated with early recurrence and cancerization. We then developed a staging system to predict early recurrence and cancerization. METHODS: All of the primary craniofacial ameloblastoma patients treated in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were recorded...
June 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/28725522/pathogenetic-analysis-of-sinonasal-teratocarcinosarcomas-reveal-actionable-%C3%AE-catenin-overexpression-and-a-%C3%AE-catenin-mutation
#5
Andrew C Birkeland, Sarah J Burgin, Megan Yanik, Megan V Scott, Carol R Bradford, Jonathan B McHugh, Scott A McLean, Stephen E Sullivan, Jacques E Nor, Erin L McKean, J Chad Brenner
Objective  Sinonasal teratocarcinosarcomas are rare, aggressive tumors of the skull base. Treatment options are limited and outcomes are poor. Little is known in regard to the genetic factors regulating these tumors. Characterization of actionable molecular alterations in these tumors could provide potentially successful therapeutic options. Methods  We performed targeted exome sequencing on an index sinonasal teratocarcinosarcoma specimen to identify potential driver mutations. We performed immunohistochemical stains for β-catenin on paraffin-embedded tissue on the index tumor and a subsequent teratocarcinosarcoma...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28725518/preferences-and-utilities-for-health-states-after-treatment-of-olfactory-groove-meningioma-endoscopic-versus-open
#6
Christopher M Yao, Alyssa Kahane, Eric Monteiro, Fred Gentili, Gelareh Zadeh, John R de Almeida
Objectives  The purpose of this study is to report health utility scores for patients with olfactory groove meningiomas (OGM) treated with either the standard transcranial approach, or the expanded endonasal endoscopic approach. Design  The time trade-off technique was used to derive health utility scores. Setting  Healthy individuals without skull base tumors were surveyed. Main Outcome Measures  Participants reviewed and rated scenarios describing treatment (endoscopic, open, stereotactic radiation, watchful waiting), remission, recurrence, and complications associated with the management of OGMs...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28725517/preoperative-embolization-for-skull-base-meningiomas
#7
Kensuke Suzuki, Masaya Nagaishi, Yoshiyuki Matsumoto, Yoshiko Fujii, Yuki Inoue, Yoshiki Sugiura, Koji Hirata, Ryotaro Suzuki, Yosuke Kawamura, Ryuta Nakae, Yoshihiro Tanaka, Akio Hyodo
The results of preoperative embolization for skull base meningiomas were retrospectively evaluated to confirm the efficacy of this procedure. Skull base meningiomas that were treated with preoperative embolization were evaluated in 20 patients. The occluded arteries, embolic materials, treatment time, excision rate, neurologic manifestations, and complications were analyzed. The embolic material was 80% liquid, 30% coils, and 15% particles. The surgery was normally completed within 3 to 5 hours. Blood loss was normally approximately 250 mL, excluding four patients having the following conditions: malignant meningioma, a large tumor located on the medial side of the sphenoidal ridge, the petroclival tumor, and infiltrated tumor into the sigmoid sinus...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28713744/access-osteotomy-in-the-maxillofacial-skeleton
#8
REVIEW
K Kamalpathey, Maj Gen N K Sahoo, Col P K Chattopadhyay, Maj Yuvraj Issar
Surgical accesses for the facial skeleton are based on the concept of modular osteotomies. Various techniques and combination of osteotomies facilitate access to the most inaccessible tumors of craniomaxillofacial region. Most appropriate surgical access is determined by considering size, location, extension of the tumor, and experience of the surgical team. These are primarily used for tumors in the nasopharynx or the skull base. The aim of this paper is to review surgical accesses that aid in removal of inaccessible tumors of craniomaxillofacial region with series of cases operated in the Department of Oral and Maxillofacial Surgery, Armed Forces Medical College, Pune, India, between July 2008 and June 2010...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28708652/clinical-application-of-multimodal-neuronavigation-system-in-neuroendoscope-assisted-skull-base-chordoma-resection
#9
Xin Wang, Long Li, Yibao Wang, Jinqu Hu, Jinpeng Zhou, Zhitao Jing, Anhua Wu
Skull base chordoma is a rare tumor arising from embryonic remnants of the notochord with invasive potential. Due to the destruction of osseous landmarks and invasion of surrounding structures, surgical resection is challenging. The authors explored the clinical value of a multimodal neuronavigation system in skull base chordoma resection using a neuroendoscope. Between January 2012 and January 2016, the authors utilized neuroendoscopy to excise skull base chordoma in 93 patients. The authors performed 45 operations assisted by multimodal neuronavigation (neuronavigation group) and 48 without intraoperative imaging guidance (control group)...
July 13, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28699066/effect-comparisons-among-treatment-measures-on-progression-free-survival-in-patients-with-skull-base-chordomas-a-retrospective-study-of-234-post-surgical-cases
#10
Liang Wang, Kaibing Tian, Junpeng Ma, Ke Wang, Guijun Jia, Zhen Wu, Liwei Zhang, Junting Zhang
BACKGROUND: Skull base chordoma (SBC) is a rare and refractory tumor with a high rate of relapse. We aimed to investigate the relationships between different treatment measures and progression-free survival (PFS) outcomes. METHODS: Data from 234 SBC patients from one institution were retrieved from a prospectively maintained database. After grouping, the clinicopathological features and mean estimated PFS times were subject to inter-group and intra-group comparisons, and prognostic factors of PFS were estimated by statistical analyses...
July 11, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28692497/the-safety-and-accuracy-of-surgical-navigation-technology-in-the-treatment-of-lesions-involving-the-skull-base
#11
Bin Wei, Guowen Sun, Qingang Hu, Enyi Tang
OBJECTIVE: As compared with the normal anatomy, structures of the skull base and its surroundings have been dramatically altered of the lesion near the skull base. How to remove the lesion at the skull base was mainly depending on surgeon's personal experience during past years. In this study, the authors explored the safety and accuracy of the surgical navigation system in resecting lesions near the skull base. METHODS: The surgical cases consisted of 15 patients who underwent surgery involving the skull base with the using of surgical navigation technology...
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28689974/endoscopic-surgery-for-sinonasal-tumors-the-transcribriform-approach
#12
R Thomas, P Martin, D Patrick, M Justin
Over the past 10 to 20 years, endoscopic endonasal surgery has become for many teams the preferred treatment for sinonasal tumors. Technical advances in the field of surgical instrumentation (good visualization, hemostasis…) and the progress of imaging guidance (to avoid neurovascular complication) has made those procedures simpler and safer. Nevertheless, endonasal endoscopic procedures require a trained surgical team of ENT specialist and neurosurgeon. Endoscopic endonasal surgery has been reported to be feasible for all types of sinonasal tumors whether benign tumors such as inverted papillomas, or malignant tumors...
July 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28689230/the-extended-transnasal-transsphenoidal-approach-for-anterior-skull-base-meningioma-considerations-in-patient-selection
#13
Joseph P Castlen, David J Cote, Hasan A Zaidi, Edward R Laws
PURPOSE: In this study, we set out to define our institutional criteria for patient eligibility for transsphenoidal resection of parasellar meningiomas, and to report our experience with extended transnasal approaches for these lesions. We aimed to discuss the important considerations of patient selection and risk stratification to optimize outcomes for patients with these difficult lesions, and also include considerations that should be reviewed during surgical approach selection. METHODS: Medical records from Brigham and Women's Hospital were retrospectively reviewed for all patients who underwent transsphenoidal surgery for pituitary disease with the senior author from April 2008 to March 2017 (938 procedures)...
July 8, 2017: Pituitary
https://www.readbyqxmd.com/read/28686110/role-of-endoscopic-transnasal-surgery-for-skull-base-chondrosarcoma-a-retrospective-analysis-of-19-cases-at-a-single-institution
#14
Hirotaka Hasegawa, Masahiro Shin, Kenji Kondo, Shunya Hanakita, Akitake Mukasa, Taichi Kin, Nobuhito Saito
OBJECTIVE Skull base chondrosarcoma is one of the most intractable tumors because of its aggressive biological behavior and involvement of the internal carotid artery and cranial nerves (CNs). One of the most accepted treatment strategies for skull base chondrosarcoma has been surgical removal of the tumor in conjunction with proactive extensive radiation therapy (RT) to the original tumor bed. However, the optimal strategy has not been determined. The goal of this study was to evaluate the early results of endoscopic transnasal surgery (ETS)...
July 7, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28677936/impact-of-optic-canal-decompression-on-visual-outcome-in-subtotal-resected-skull-base-meningiomas
#15
Meike Unteroberdörster, Oliver Müller, Neriman Özkan, Daniela Pierscianek, Martin Hadamitzky, Bernadette Kleist, Ulrich Sure, Nicolai El Hindy
BACKGROUND: Visual impairment (VI) due to neoplastic infiltration of the optic canal (OC) is frequently seen in skull base meningiomas representing a significant restriction in patients` quality of life. However, the delicate anatomy of this region often prevents gross total tumor resection. The aim of the present study was to evaluate the impact of intradural OC decompression and postoperative oncological procedure on preservation of visual acuity in subtotal resected skull base meningiomas...
July 4, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28673887/clinical-radiological-and-pathological-features-of-56-cases-of-intracranial-lymphoplasmacyte-rich-meningioma
#16
Xiaogang Tao, Kun Wang, Jinqian Dong, Zonggang Hou, Zhen Wu, Junting Zhang, Baiyun Liu
OBJECTIVE: Intracranial lymphoplasmacyte-rich meningioma (LPRM) is rarely reported because of its extremely low incidence, and current understanding of this disease is poor. We analyzed the incidence and clinical, radiological, pathological, and prognostic features of intracranial LPRMs. METHODS: Approximately 10,908 intracranial meningiomas were surgically resected in Beijing Tiantan Hospital between June 2009 and November 2016. All pathologically proven LPRM cases were identified...
June 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28673886/newly-diagnosed-sellar-tumors-in-cancer-patients-a-diagnostic-challenge-and-management-dilemma
#17
Carlos R Goulart, Smita Upadhyay, Leo F S Ditzel Filho, Andre Beer-Furlan, Ricardo L Carrau, Luciano M Prevedello, Daniel M Prevedello
OBJECTIVE: The use of PET CT for staging in cancer patients and the widespread use of MRI led to an increased incidence of incidental sellar mass detection. The imaging findings can be suggestive of a benign pituitary tumor but metastasis can never be completely ruled out with non-invasive work-up. Appropriate diagnosis of these sellar masses is critical as the treatment paradigm might change in the presence of a pituitary metastasis. Moreover, definitive tissue diagnosis might prevent unnecessary radiotherapy to the skull base or even the need for systemic treatment when benign pituitary disease is confirmed...
June 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28667597/stereotactic-radiotherapy-as-primary-definitive-or-postoperative-treatment-of-intracranial-meningioma-of-who-grade-ii-and-iii-leads-to-better-disease-control-than-stereotactic-radiotherapy-of-recurrent-meningioma
#18
Dorota Lubgan, Sandra Rutzner, Ulrike Lambrecht, Karl Rössler, Michael Buchfelder, Ilker Eyüpoglu, Rainer Fietkau, Sabine Semrau
The aim of this study was to evaluate long-term clinical outcome, prognostic factors and quality of life after adjuvant or definitive fractionated stereotactic radiotherapy (SRT) of meningioma WHO grade II and III or at recurrence. 131 patients with 138 meningioma (64 WHO grade II, 16 WHO grade III, 58 without histology) of the skull base, falx and convexity were treated between 01/2002 and 01/2015 at the Erlangen University Hospital by fractionated stereotactic radiotherapy (SRT) as primary treatment (adjuvant or definitive) and at recurrence...
June 30, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28667391/-tumors-of-the-sellar-region
#19
REVIEW
J M Lieb, F J Ahlhelm
METHODICAL ISSUE: The anatomy of the sellar region is complex and tumors of the sellar region are very variable because they arise from the many different tissue types in the sellar region, ranging from benign to life-threatening. Despite this variety, approximately 80% of sellar region tumors are due to the 5 most common lesions: adenomas, meningiomas, aneurysms, astrocytomas and craniopharyngiomas. STANDARD RADIOLOGICAL METHODS: In addition to clinical and laboratory results, the magnetic resonance imaging (MRI) and computed tomography (CT) results including the exact anatomical position and the proliferation pattern of the lesion are decisive for the diagnosis...
June 30, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28665391/-tactics-of-reconstructive-closure-of-basal-defects-after-resection-of-midline-tumors-of-the-anterior-skull-base-a-literature-review
#20
D A Gol'bin, S N Mindlin
The purpose of this review is to analyze the techniques used to reconstruct midline defects in the anterior skull base after transcranial and endoscopic endonasal resection of skull base tumors. We provide brief information on the technique for preparing various flaps, indications and contraindications, and advantages and disadvantages. We analyze the international experience in the use of vascularized and non-vascularized flaps as well as the existing algorithms for reconstruction of complex defects of the midline structures of the skull base...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
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