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Far lateral approach

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https://www.readbyqxmd.com/read/29649954/anatomical-considerations-and-open-surgery-to-treat-juxtarenal-abdominal-aortic-aneurysms
#1
Georgiana Samoila, Ian Michael Williams
INTRODUCTION: Historically, the open approach to the abdominal aorta has been transperitoneal (TP). In comparison, a retroperitoneal (RP) incision exposes the lateral wall of the suprarenal aorta for clamp application and midline structures such as the duodenum and pancreas are not encountered. Proximal clamp position for open repair of juxtarenal abdominal aortic aneurysm (JR-AAA) is suprarenal, supra-superior mesenteric, or supraceliac. While RP and TP approaches have previously been compared for physiological reasons, there are currently no randomized controlled trials comparing these methods from an anatomical perspective...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29623081/a-new-in-vivo-model-to-study-protective-immunity-to-zika-virus-infection-in-mice-with-intact-type-i-interferon-signaling
#2
Loulieta Nazerai, Amalie Skak Schøller, Peter Overbeck Sharma Rasmussen, Søren Buus, Anette Stryhn, Jan Pravsgaard Christensen, Allan Randrup Thomsen
The association between recent Zika virus (ZIKV) infection and neurological complications, microcephaly in the fetus, and Guillain-Barré syndrome in adults underscores the necessity for a protective vaccine. Rational vaccine development requires an in-depth understanding of the mechanisms which could protect against infection with this virus. However, so far, such an analysis has been hampered by the absence of a suitable small animal model. Unlike the situation in humans, ZIKV only replicates effectively in the peripheral organs of mice, if type I IFN signaling is interrupted...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29621594/rock-inhibition-in-models-of-neurodegeneration-and-its-potential-for-clinical-translation
#3
REVIEW
Jan Christoph Koch, Lars Tatenhorst, Anna-Elisa Roser, Kim-Ann Saal, Lars Tönges, Paul Lingor
Neurodegenerative disorders like Parkinson's disease, Alzheimer's disease, or amyotrophic lateral sclerosis are affecting a rapidly increasing population worldwide. While common pathomechanisms such as protein aggregation, axonal degeneration, dysfunction of protein clearing and an altered immune response have been characterized, no disease-modifying therapies have been developed so far. Interestingly, a significant involvement of the Rho kinase (ROCK) signaling pathway has been described in all of these mechanisms making it a promising target for new therapeutic approaches...
April 2, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29589455/-supracondylar-fracture-of-the-humerus-in-childhood
#4
P Havránek, T Pešl, J Hendrych, M Kučerová
INTRODUCTION: Supracondylar fracture of the humerus can be considered the most serious fracture in childhood. Problems with its diagnostics and treatment as well as its complications and sequels have not been fully solved yet. That is evidenced by a large amount of articles with frequently inconsistent conclusions. The aim is to evaluate contemporary diagnostic and therapeutic approach based on our own clinical experience. METHODS: A total of 2847 children with skeletal injury were treated by the authors during the year 2016...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29579392/template-assisted-scalable-nanowire-networks
#5
Martin Friedl, Kristopher Kristopher Cerveny, Pirmin Weigele, Gözde Tütüncüoglu, Sara Marti-Sanchez, Chunyi Huang, Taras Patlatiuk, Heidi Potts, Zhiyuan Sun, Megan O Hill, Lucas Güniat, Wonjong Kim, Mahdi Zamani, Vladimir G Dubrovskii, Jordi Arbiol, Lincoln J Lauhon, Dominik Max Zumbühl, Anna Fontcuberta I Morral
Topological qubits based on Majorana fermions have the potential to revolutionize the emerging field of quantum computing by making information processing significantly more robust to decoherence. Nanowires (NWs) are a promising medium for hosting these kinds of qubits, though branched NWs are needed to perform qubit manipulations.3 Here we report gold-free templated growth of III-V NWs by molecular beam epitaxy using an approach that enables patternable and highly regular branched NW arrays on a far greater scale than what has been reported thus far...
March 26, 2018: Nano Letters
https://www.readbyqxmd.com/read/29573996/from-melody-to-words-the-role-of-sex-hormones-in-early-language-development
#6
REVIEW
Kathleen Wermke, Anja Quast, Volker Hesse
Human infants are the most proficient of the few vocal learner species. Sharing similar principles in terms of the generation and modification of complex sounds, cross-vocal learner comparisons are a suitable strategy when it comes to better understanding the evolution and mechanisms of auditory-vocal learning in human infants. This approach will also help us to understand sex differences in relation to vocal development towards language, the underlying brain mechanisms thereof and sex-specific hormonal effects...
March 21, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29570012/validation-of-diffusion-tensor-imaging-tractography-to-visualize-the-dentatorubrothalamic-tract-for-surgical-planning
#7
Andreas Nowacki, Jürgen Schlaier, Ines Debove, Claudio Pollo
OBJECTIVE The dentatorubrothalamic tract (DRTT) has been suggested as the anatomical substrate for deep brain stimulation (DBS)-induced tremor alleviation. So far, little is known about how accurately and reliably tracking results correspond to the anatomical DRTT. The objective of this study was to systematically investigate and validate the results of different tractography approaches for surgical planning. METHODS The authors retrospectively analyzed 4 methodological approaches for diffusion tensor imaging (DTI)-based fiber tracking using different regions of interest in 6 patients with essential tremor...
March 23, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29541887/how-i-do-it-surgical-clipping-of-vertebrobasilar-junction-aneurysms-through-a-far-lateral-transcondylar-approach
#8
Vladimir Nakov, Toma Spiriev, Evgeni Stavrev
BACKGROUND: Vertebrobasilar junction aneurysms occur rarely, but have a higher rupture rate than supratentoral aneurysms, and higher morbidity and mortality. Their location ventral to the neuroaxis makes them a challenging surgical lesion. METHODS: In this paper, we share our experience with the surgical technique for the management of these complex aneurysms. CONCLUSION: An in-depth understanding of the anatomy of these aneurysms, careful preoperative planning, and a meticulous surgical technique, including knowledge of every detail of the procedure-positioning, an advanced skull base technique, and careful aneurysm dissection and clipping-is essential for a successful outcome of the surgery...
March 14, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29537957/beyond-the-scope-open-treatment-of-femoroacetabular-impingement
#9
Michael Ryan, Thomas Youm, Jonathan Vigdorchik
Hip arthroscopy as we know it today developed over the last 15 to 20 years, yet its true beginning is far more dated. Initially developed as a means of removing loose bodies or as a means of lavage, hip arthroscopy was not utilized to treat femoroacetabular impingement (FAI) until much later. Its usefulness as a means of treating FAI did not arise until hip impingement was understood to be causal in the development of degenerative changes of the labrum and articular surfaces. As our understanding of FAI grew, the tools for treating it developed in tandem...
March 2018: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/29527396/how-to-perform-the-wiltse-posterolateral-spinal-approach-technical-note
#10
A Guiroy, A Sícoli, N Gonzalez Masanés, A Morales Ciancio, M Gagliardi, A Falavigna
Background: The paraspinal, posterolateral, or Wiltse approach is an old technique that observes the principles of an MIS procedure. The aim of this study was to provide a step-by-step description from the literature of the Wiltse paraspinal approach and analyze its main advantages and limitations. Methods: Here, we provide a step-by-step description of the Wiltse approach. Utilizing PubMed and Lilacs and the Mesh terms "Wiltse approach," "paraspinal approach," "muscle sparing approach," and "lumbar spine," we identified 10 papers...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29521811/carbenoxolone-as-a-novel-therapy-for-attenuation-of-cancer-induced-bone-pain
#11
Sarah Falk
Pain is a major complication for cancer patients significantly compromising their quality of life. Current treatment is far from optimal and particularly bone-related cancer pain poses an increasing clinical and socio-economical problem. Connexins, key proteins in cell-cell communication, have the potential to affect cancer-induced bone pain at multiple levels, including nociceptive signaling and bone degradation. This study tested the analgesic potential of carbenoxolone, a broad-acting connexin blocker, in a mouse model of cancer-induced bone pain...
March 6, 2018: Pain
https://www.readbyqxmd.com/read/29499424/transnasal-endoscopic-and-lateral-approaches-to-the-clivus-a-quantitative-anatomical-study
#12
Francesco Doglietto, Marco Ferrari, Davide Mattavelli, Francesco Belotti, Vittorio Rampinelli, Hussein Kheshaifati, Davide Lancini, Alberto Schreiber, Tommaso Sorrentino, Marco Ravanelli, Barbara Buffoli, Lena Hirtler, Roberto Maroldi, Piero Nicolai, Luigi Rodella, Marco Maria Fontanella
BACKGROUND: Transnasal endoscopic approaches to the clivus have been recently established. Comparative analyses with "classic" lateral approaches are limited. OBJECTIVE: To compare transnasal endoscopic and lateral approaches to the clivus, quantifying exposure and working volume of each approach in the anatomy laboratory. MATERIALS AND METHODS: Five injected specimens (10 sides) underwent high-resolution computed tomography. In each specimen, transnasal endoscopic (Paraseptal, Transrostral, Extended Transrostral, Transethmoidal, Extended Transclival approach without and with intradural hypophysiopexy) and lateral approaches (Retrosigmoid, Far-lateral, Presigmoid retro- and trans-labyrinthine) to the clivus were performed...
February 27, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29493041/sleep-deprivation-compromises-resting-state-emotional-regulatory-processes-an-eeg-study
#13
Jinxiao Zhang, Esther Yuet Ying Lau, Janet H Hsiao
Resting-state spontaneous neural activities consume far more biological energy than stimulus-induced activities, suggesting their significance. However, existing studies of sleep loss and emotional functioning have focused on how sleep deprivation modulates stimulus-induced emotional neural activities. The current study aimed to investigate the impacts of sleep deprivation on the brain network of emotional functioning using electroencephalogram during a resting state. Two established resting-state electroencephalogram indexes (i...
March 1, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29483070/enhancing-survivorship-care-planning-for-patients-with-localized-prostate-cancer-using-a-couple-focused-mhealth-symptom-self-management-program-protocol-for-a-feasibility-study
#14
Lixin Song, Kaitlyn L Dunlap, Xianming Tan, Ronald C Chen, Matthew E Nielsen, Rebecca L Rabenberg, Josephine K Asafu-Adjei, Bridget F Koontz, Sarah A Birken, Laurel L Northouse, Deborah K Mayer
BACKGROUND: This project explores a new model of care that enhances survivorship care planning and promotes health for men with localized prostate cancer transitioning to posttreatment self-management. Survivorship care planning is important for patients with prostate cancer because of its high incidence rate in the United States, the frequent occurrence of treatment-related side effects, and reduced quality of life (QOL) for both men and their partners. A key component of comprehensive survivorship care planning is survivorship care plans (SCPs), documents that summarize cancer diagnosis, treatment, and plans for follow-up care...
February 26, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29479657/quantitative-evaluation-of-different-far-lateral-approaches-to-the-cranio-vertebral-junction-using-the-microscope-and-the-endoscope-a-cadaveric-study-using-a-tumor-model
#15
Pengfei Wu, Roberto Colasanti, Jungshun Lee, Alba Scerrati, Serdar Ercan, Jun Zhang, Mario Ammirati
BACKGROUND: Several far lateral approaches have been proposed to deal with cranio-vertebral junction (CVJ) tumors including the basic, transcondylar, and supracondylar far lateral approaches (B-FLA, T-FLA, and S-FLA). However, the indications on when to use one versus the other are not well systematized yet. Our purpose is to evaluate in an experimental cadaveric setting which approach is best suited to remove tumors of different sizes. METHODS: We implanted at the CVJ, using a transoral approach, tumor models of different sizes (five 1-cm3 and five 3-cm3 tumors) in ten embalmed cadaveric heads...
February 26, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29477700/the-nuchal-lines-as-anatomical-landmarks-to-dissect-the-muscles-in-the-far-lateral-approach
#16
Alvaro Campero, Juan F Villalonga, Ramiro Lopez Elizalde, Pablo Ajler
BACKGROUND: A critical step in the far lateral approach (FLA) is the exposure of V3 segment of the vertebral artery (VA), located in the depth of the suboccipital triangle (SOT). A safe exposure of the SOT is achieved by means of a plane-by-plane dissection, which carries the risk of devascularization. A suitable alternative is to lift a cutaneous muscle flap including the 3 first muscle planes, and leave the deepest plane (SOT) attached to the skull base. To achieve this, it is necessary to have superficial anatomic repairs to help us identify our cleavage site...
February 22, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29458230/perioperative-complications-of-congenital-diaphragmatic-hernia-repair
#17
Catarina Barroso, Jorge Correia-Pinto
Although improvements have been made, the management of congenital diaphragmatic hernia (CDH) remains a major challenge for perinatologists and neonatal surgeons. Many aspects of the disease remain unknown and, being a rare entity, evidence-based data are hard to find. Surgical morbidity is considerable and affects long-term quality of life. Perioperative complications have been reviewed focusing on thoracoscopic repair. Intraoperative acidosis was more severe during thoracoscopy when compared with open surgery (OS), though it is possible that later neurodevelopment was not affected...
February 19, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29444272/right-far-lateral-approach-for-resection-of-foramen-magnum-meningioma-3-dimensional-operative-video
#18
William T Couldwell
No abstract text is available yet for this article.
February 10, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29431820/single-crystal-diamond-membranes-for-nanoelectronics
#19
Kerem Bray, Hiromitsu Kato, Rodolfo Previdi, Russell Sandstrom, Kumaravelu Ganesan, Masahiko Ogura, Toshiharu Makino, Satoshi Yamasaki, Andrew P Magyar, Milos Toth, Igor Aharonovich
Single crystal, nanoscale diamond membranes are highly sought after for a variety of applications including nanophotonics, nanoelectronics and quantum information science. However, so far, the availability of conductive diamond membranes has remained an unreachable goal. In this work we present a complete nanofabrication methodology for engineering high aspect ratio, electrically active single crystal diamond membranes. The membranes have large lateral directions, exceeding ∼500 × 500 μm2 and are only several hundreds of nanometers thick...
February 12, 2018: Nanoscale
https://www.readbyqxmd.com/read/29429397/pre-movement-and-during-movement-visual-search-behaviours-vary-depending-on-expertise-and-anxiety-levels-in-ten-pin-bowling
#20
Wan Xiu Goh, Bernice H Y Lim, Matthew James Wylde, Michele Macnaughton, Jia Yi Chow, Marcus J C Lee
This study investigated the pre-movement and during-movement visual search behaviour (VSB) and quiet eye (QE) of 11 elite versus 10 sub-elite ten-pin bowlers, performing under high-anxiety and low-anxiety conditions. Pre-movement and independent of expertise, bowlers had more fixations and directed them to more locations when performing under high-anxiety compared with low-anxiety. Elite bowlers fixated at more locations closer to the pins in pre-movement than during-movement, with pre-movement QE occurring mostly at the breakpoint and middle arrows...
February 10, 2018: Journal of Sports Sciences
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