Nerea Méndez-Barbero, Carmen Gutiérrez-Muñoz, Rafael Blázquez-Serra, José Luis Martín-Ventura, Luis Miguel Blanco-Colio
The annexin superfamily consists of 12 proteins with a highly structural homology that binds to phospholipids depending on the availability of Ca2+ -dependent. Different studies of overexpression, inhibition, or using recombinant proteins have linked the main function of these proteins to their dynamic and reversible binding to membranes. Annexins are found in multiple cellular compartments, regulating different functions, such as membrane trafficking, anchoring to the cell cytoskeleton, ion channel regulation, as well as pro- or anti-inflammatory and anticoagulant activities...
February 20, 2021: Clínica e Investigación en Arteriosclerosis