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resonance prostate multiparametric

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https://www.readbyqxmd.com/read/29135073/prostate-cancer-detection-using-quantitative-t2-and-t2-weighted-imaging-the-effects-of-5-alpha-reductase-inhibitors-in-men-on-active-surveillance
#1
Francesco Giganti, Giulio Gambarota, Caroline M Moore, Nicola L Robertson, Neil McCartan, Charles Jameson, Simon R J Bott, Mathias Winkler, Brandon Whitcher, Ramiro Castro-Santamaria, Mark Emberton, Clare Allen, Alex Kirkham
BACKGROUND: T2 -weighted imaging (T2 -WI) information has been used in a qualitative manner in the assessment of prostate cancer. Quantitative derivatives (T2 relaxation time) can be generated from T2 -WI. These outputs may be useful in helping to discriminate clinically significant prostate cancer from background signal. PURPOSE/HYPOTHESIS: To investigate changes in quantitative T2 parameters in lesions and noncancerous tissue of men on active surveillance for prostate cancer taking dutasteride 0...
November 14, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29133278/imaging-for-the-detection-of-locoregional-recurrences-in-biochemical-progression-after-radical-prostatectomy-a-systematic-review
#2
REVIEW
Kristina Sandgren, Philippe Westerlinck, Joakim H Jonsson, Lennart Blomqvist, Camilla Thellenberg Karlsson, Tufve Nyholm, Piet Dirix
CONTEXT: Local and regional recurrence after radical prostatectomy (RP) can be treated using salvage radiotherapy (SRT). If the recurrence can be delineated on diagnostic imaging, this could allow for increasingly individualized SRT. OBJECTIVE: This systematic review aimed at evaluating the evidence regarding the usefulness of positron emission tomography (PET) and magnetic resonance imaging (MRI) in identifying local and regional recurrences, with the aim to further individualize the SRT treatment...
November 10, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29126575/validation-of-prostate-imaging-reporting-and-data-system-version-2-a-retrospective-analysis
#3
Michael Nguyentat, Alexander Ushinsky, Alessandra Miranda-Aguirre, Edward Uchio, Chandana Lall, Layla Shirkhoda, Thomas Lee, Christopher Green, Roozbeh Houshyar
PURPOSE: Use of magnetic resonance imaging (MRI)/transrectal ultrasound fusion biopsies to determine the accuracy of multiparametric MRI (mpMRI), using Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2), for detecting clinically significant prostate cancer in the overall gland and specifically the peripheral zone (PZ) and transitional zone (TZ). METHODS: A retrospective analysis of patients who underwent fusion biopsy identified 137 men with 231 prostate lesions was approved by the Institutional Review Board...
October 12, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29115970/comparison-of-68-ga-psma-11-pet-ct-with-mpmri-for-preoperative-lymph-node-staging-in-patients-with-intermediate-to-high-risk-prostate-cancer
#4
Qing Zhang, Shiming Zang, Chengwei Zhang, Yao Fu, Xiaoyu Lv, Qinglei Zhang, Yongming Deng, Chuan Zhang, Rui Luo, Xiaozhi Zhao, Wei Wang, Feng Wang, Hongqian Guo
BACKGROUND: To evaluate the diagnostic value of (68)Ga-PSMA-11 PET-CT with multiparametric magnetic resonance imaging (mpMRI) for lymph node (LN) staging in patients with intermediate- to high-risk prostate cancer (PCa) undergoing radical prostatectomy (RP) with pelvic lymph node dissection (PLND). METHODS: We retrospectively identified 42 consecutive patients with intermediate- to high-risk PCa according to D'Amico and without concomitant cancer. Preoperative (68)Ga-PSMA-11 PET-CT, pelvic mpMRI and subsequent robot assisted laparoscopic RP with PLND were performed in all patients...
November 7, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29111176/fluorine-18-prostate-specific-membrane-antigen-1007-positron-emission-tomography-computed-tomography-and-multiparametric-magnetic-resonance-imaging-in-diagnostics-of-local-recurrence-in-a-prostate-cancer-patient-after-recent-radical-prostatectomy
#5
Kiryl Paddubny, Martin T Freitag, Clemens Kratochwil, Stefan Koerber, Jan P Radtke, Ruslan Sakovich, Klaus Kopka, Frederik L Giesel
No abstract text is available yet for this article.
October 5, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29107031/prospective-multicenter-phase-ii-study-on-focal-therapy-hemiablation-of-the-prostate-with-high-intensity-focused-ultrasound-hifu
#6
Roman Ganzer, Boris Hadaschik, Sascha Pahernik, Daniel Koch, Daniel Baumunk, Timur Kuru, Axel Heidenreich, Jens-Uwe Stolzenburg, Martin Schostak, Andreas Blana
PURPOSE: To evaluate Focal therapy (FT) by means of high-intensity focussed ultrasound (HIFU) hemiablation in a prospective trial. MATERIALS AND METHODS: Prospective multicentre single arm study in patients with unilateral low/intermediate risk PC, treated from April 2013 through March 2016 in Germany (AUO study protocol AP 68/11). Unilateral PC was assessed by transrectal ultrasound (TRUS)-guided biopsy and multiparametric magnetic resonance imaging (mpMRI). Hemiablation was performed with the Ablatherm or Focal One device...
October 26, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29102671/preliminary-diagnostic-accuracy-of-multiparametric-magnetic-resonance-imaging-to-detect-residual-prostate-cancer-following-focal-therapy-with-irreversible-electroporation
#7
Matthijs J Scheltema, John I Chang, Willemien van den Bos, Maret Böhm, Warick Delprado, Ilan Gielchinsky, Theo M de Reijke, Jean J de la Rosette, Amila R Siriwardana, Ron Shnier, Phillip D Stricker
BACKGROUND: It is recommended to perform multiparametric magnetic resonance imaging (mpMRI) in the follow-up following focal therapy of prostate cancer (PCa). OBJECTIVE: To determine the diagnostic accuracy of mpMRI to detect residual PCa following focal therapy with irreversible electroporation. DESIGN, SETTING, AND PARTICIPANTS: Seventy-six patients with biopsy-proven localized PCa consented for primary irreversible electroporation between February 2013 and March 2016...
November 1, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29098169/optimized-b-value-selection-for-the-discrimination-of-prostate-cancer-grades-including-the-cribriform-pattern-using-diffusion-weighted-imaging
#8
Sarah L Hurrell, Sean D McGarry, Amy Kaczmarowski, Kenneth A Iczkowski, Kenneth Jacobsohn, Mark D Hohenwalter, William A Hall, William A See, Anjishnu Banerjee, David K Charles, Marja T Nevalainen, Alexander C Mackinnon, Peter S LaViolette
Multiparametric magnetic resonance imaging (MP-MRI), including diffusion-weighted imaging, is commonly used to diagnose prostate cancer. This radiology-pathology study correlates prostate cancer grade and morphology with common b-value combinations for calculating apparent diffusion coefficient (ADC). Thirty-nine patients undergoing radical prostatectomy were recruited for MP-MRI prior to surgery. Diffusion imaging was collected with seven b-values, and ADC was calculated. Excised prostates were sliced in the same orientation as the MRI using 3-D printed slicing jigs...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29094851/prospective-nonrandomized-study-of-diagnostic-accuracy-comparing-prostate-cancer-detection-by-transrectal-ultrasound-guided-biopsy-to-magnetic-resonance-imaging-with-subsequent-mri-guided-biopsy-in-biopsy-na%C3%A3-ve-patients
#9
Roberto Castellucci, Ana I Linares Quevedo, Francisco J Sánchez Gómez, Jesús Díez Rodríguez, Leopoldo Cogorno, Isidro Cogollos Acuña, Isabel Salmerón Béliz, Marta Muñoz Fernández de Legaría, Luis Martínez Piñeiro
BACKGROUND: To evaluate the diagnostic efficacy in cancer prostate (PCa) of Multiparametric prostate magnetic resonance imaging (mp-MRI) targeted biopsy compared to standard systematic transrectal ultrasound-guided biopsy (TRUSGB) in biopsy-naïve patients. METHODS: A total of 168 biopsy-naïve men with clinical suspicion of PCa due to elevated PSA levels and/or an abnormal digital rectal examination were consecutively enrolled from July 2011 to July 2014. All patients underwent TRUSGB...
December 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29093748/a-systematic-review-on-multiparametric-mr-imaging-in-prostate-cancer-detection
#10
REVIEW
Roberta Fusco, Mario Sansone, Vincenza Granata, Sergio Venanzio Setola, Antonella Petrillo
Background: Literature data suggest that multi-parametric Magnetic Resonance Imaging (MRI), including morphologic T2-weigthed images (T2-MRI) and functional approaches such as Dynamic Contrast Enhanced-MRI (DCE-MRI), Diffusion Weighted Imaging (DWI) and Magnetic Resonance Spectroscopic Imaging (MRSI), give an added value in the prostate cancer localization and local staging. Methods: We performed a systematic review of literature about the role and the potentiality of morphological and functional MRI in prostate cancer, also in a multimodal / multiparametric approach, and we reported the diagnostic accuracy results for different imaging modalities and for different MR coil settings: endorectal coil (ERC) and phased array coil (PAC)...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29083999/multiparametric-mri-fusion-guided-biopsy-for-the-diagnosis-of-prostate-cancer
#11
Claudia Kesch, Viktoria Schütz, Svenja Dieffenbacher, David Bonekamp, Boris Alexander Hadaschik, Markus Hohenfellner, Jan P Radtke
PURPOSE OF REVIEW: To discuss the timing, benefits, limitations and current controversies of multiparametric magnet resonance imaging (mpMRI) combined with fusion-guided biopsy and consider how additional incorporation of multivariable risk stratification might further improve prostate cancer diagnosis. RECENT FINDINGS: MpMRI has been proven advantageous over standard practice for biopsy-naïve men and men with previous biopsy in large prospective studies providing level 1b evidence...
October 27, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/29077588/implementation-of-a-5-minute-magnetic-resonance-imaging-screening-protocol-for-prostate-cancer-in-men-with-elevated-prostate-specific-antigen-before-biopsy
#12
Jakob Weiss, Petros Martirosian, Mike Notohamiprodjo, Sascha Kaufmann, Ahmed E Othman, Ulrich Grosse, Konstantin Nikolaou, Sergios Gatidis
PURPOSE: The aims of this study were to establish a 5-minute magnetic resonance (MR) screening protocol for prostate cancer in men before biopsy and to evaluate effects on Prostate Imaging Reporting and Data System (PI-RADS) V2 scoring in comparison to a conventional, fully diagnostic multiparametric MR imaging (mpMRI) approach. MATERIALS AND METHODS: Fifty-two patients with elevated prostate-specific antigen levels and without prior biopsy were prospectively included in this institutional review board-approved study...
October 26, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/29074136/new-approach-to-guide-target-prostate-biopsy-technique-and-initial-experience
#13
Enrique Gómez Gómez, José Valero Rosa, Julia Carrasco Valiente, Francisco Triviño Tarradas, Francisco Anglada Curado, Daniel López Ruiz, María José Requena Tapia
OBJECTIVE: To describe the technique of transrectal biopsy with a new device that fuses multiparametric magnetic resonance (mpMRI) and ultrasound images in real time to guide target biopsies and to evaluate our initial experience. METHODS: Patients with persistent suspicion of prostate cancer despite a previous negative biopsy and who had an mpMRI before the biopsy were selected. All patients underwent target biopsy plus standard systematic biopsy. Significant prostate cancer (sig PCa) was defined according to the Epstein criteria for standard biopsy and Gleason grade of >7 and a positive core length of >5 mm for target biopsy...
September 4, 2017: Urology
https://www.readbyqxmd.com/read/29063480/an-update-of-pitfalls-in-prostate-mpmri-a-practical-approach-through-the-lens-of-pi-rads-v-2-guidelines
#14
REVIEW
Valeria Panebianco, Francesco Giganti, Yu Xuan Kitzing, François Cornud, Riccardo Campa, Gianluca De Rubeis, Antonio Ciardi, Carlo Catalano, Geert Villeirs
OBJECTIVES: The aim of the current report is to provide an update in the imaging interpretation of prostate cancer on multiparametric magnetic resonance imaging (mpMRI), with a special focus on how to discriminate pathological tissue from the most common pitfalls that may be encountered during daily clinical practice using the Prostate Imaging Reporting and Data System (PI-RADS) version 2 guidelines. METHODS: All the cases that are shown in this pictorial review comply with the European Society of Urogenital Radiology (ESUR) guidelines for technical mpMRI requirements...
October 23, 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/29057288/fully-automated-segmentation-of-prostate-whole-gland-and-transition-zone-in-diffusion-weighted-mri-using-convolutional-neural-networks
#15
Tyler Clark, Junjie Zhang, Sameer Baig, Alexander Wong, Masoom A Haider, Farzad Khalvati
Prostate cancer is a leading cause of cancer-related death among men. Multiparametric magnetic resonance imaging has become an essential part of the diagnostic evaluation of prostate cancer. The internationally accepted interpretation scheme (Pi-Rads v2) has different algorithms for scoring of the transition zone (TZ) and peripheral zone (PZ) of the prostate as tumors can appear different in these zones. Computer-aided detection tools have shown different performances in TZ and PZ and separating these zones for training and detection is essential...
October 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29053402/what-are-we-missing-false-negative-cancers-at-multiparametric-mr-imaging-of-the-prostate
#16
Samuel Borofsky, Arvin K George, Sonia Gaur, Marcelino Bernardo, Matthew D Greer, Francesca V Mertan, Myles Taffel, Vanesa Moreno, Maria J Merino, Bradford J Wood, Peter A Pinto, Peter L Choyke, Baris Turkbey
Purpose To characterize clinically important prostate cancers missed at multiparametric (MP) magnetic resonance (MR) imaging. Materials and Methods The local institutional review board approved this HIPAA-compliant retrospective single-center study, which included 100 consecutive patients who had undergone MP MR imaging and subsequent radical prostatectomy. A genitourinary pathologist blinded to MP MR findings outlined prostate cancers on whole-mount pathology slices. Two readers correlated mapped lesions with reports of prospectively read MP MR images...
October 20, 2017: Radiology
https://www.readbyqxmd.com/read/29046984/spatial-tracking-of-targeted-prostate-biopsy-locations-moving-towards-effective-focal-partial-prostate-gland-ablation-with-improved-treatment-planning
#17
REVIEW
Steven Sidelsky, Shaan Setia, Srinivas Vourganti
The ability to selectively characterize, localize, and predict the specific areas of the prostate gland which harbor the worst biologic behavior is requisite for optimal prostate cancer therapy, especially in the emerging field of partial prostate gland ablation (focal therapy). In this manuscript, we highlight contemporary techniques in target tracking for focal therapy planning. Multiparametric magnetic resonance imaging has emerged as a dominant strategy to localize biopsy sites most likely to contain high-grade lesions...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29045233/the-current-state-of-mr-imaging-targeted-biopsy-techniques-for-detection-of-prostate-cancer
#18
REVIEW
Sadhna Verma, Peter L Choyke, Steven C Eberhardt, Aytekin Oto, Clare M Tempany, Baris Turkbey, Andrew B Rosenkrantz
Systematic transrectal ultrasonography (US)-guided biopsy is the standard approach for histopathologic diagnosis of prostate cancer. However, this technique has multiple limitations because of its inability to accurately visualize and target prostate lesions. Multiparametric magnetic resonance (MR) imaging of the prostate is more reliably able to localize significant prostate cancer. Targeted prostate biopsy by using MR imaging may thus help to reduce false-negative results and improve risk assessment. Several commercial devices are now available for targeted prostate biopsy, including in-gantry MR imaging-targeted biopsy and real-time transrectal US-MR imaging fusion biopsy systems...
November 2017: Radiology
https://www.readbyqxmd.com/read/29023572/computer-aided-detection-in-prostate-cancer-diagnostics-a-promising-alternative-to-biopsy-a-retrospective-study-from-104-lesions-with-histological-ground-truth
#19
Anika Thon, Ulf Teichgräber, Cornelia Tennstedt-Schenk, Stathis Hadjidemetriou, Sven Winzler, Ansgar Malich, Ismini Papageorgiou
BACKGROUND: Prostate cancer (PCa) diagnosis by means of multiparametric magnetic resonance imaging (mpMRI) is a current challenge for the development of computer-aided detection (CAD) tools. An innovative CAD-software (Watson Elementary™) was proposed to achieve high sensitivity and specificity, as well as to allege a correlate to Gleason grade. AIM/OBJECTIVE: To assess the performance of Watson Elementary™ in automated PCa diagnosis in our hospital´s database of MRI-guided prostate biopsies...
2017: PloS One
https://www.readbyqxmd.com/read/28990929/multiparametric-magnetic-resonance-imaging-for-active-surveillance-of-prostate-cancer
#20
Julie Y An, Abhinav Sidana, Peter L Choyke, Bradford Wood, Peter A Pinto, İsmail Barış Türkbey
Active surveillance has gained popularity as an acceptable management option for men with low-risk prostate cancer. Successful utilization of this strategy can delay or prevent unnecessary interventions - thereby reducing morbidity associated with overtreatment. The usefulness of active surveillance primarily depends on correct identification of patients with low-risk disease. However, current population-wide algorithms and tools do not adequately exclude high-risk disease, thereby limiting the confidence of clinicians and patients to go on active surveillance...
September 29, 2017: Balkan Medical Journal
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