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https://www.readbyqxmd.com/read/28225700/seeking-legitimacy-for-dsm-5-the-bereavement-exception-as-an-example-of-failed-process
#1
James E Sabin, Norman Daniels
In 2013 the American Psychiatric Association (APA) published the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Even before publication, DSM-5 received a torrent of criticism, most prominently over removal of the "bereavement exclusion" for the diagnosis of major depression. We argue that while the APA can claim legitimate authority for deciding scientific questions, it does not have legitimacy for resolving what is ultimately a question of ethics and public policy. We show how the "accountability for reasonableness" framework for seeking legitimacy in health policy could have been used to achieve a better resolution of the conflict than actually occurred...
February 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28224338/the-response-of-phosphorus-uptake-strategies-of-microcystis-aeruginosa-to-hydrodynamics-fluctuations
#2
Yue Zheng, Wujuan Mi, Yonghong Bi, Zhengyu Hu
The mechanisms of hydrodynamic fluctuation that affect cyanobacterial physiological aspects are still unclear. This study was conducted to screen the effects of hydrodynamic fluctuation on phosphorus (P) uptake by Microcystis aeruginosa. Four levels of circumfluence (0, 100, 200, and 300 rpm) and three concentrations of P (0.5, 2.0, and 5.0 mgL(-1)) were used, and the specific growth rate, cell viability, P uptake kinetic, and alkaline phosphatase activity (APA) were determined. Results showed that M. aeruginosa had a higher specific growth rate, cell viability, and P uptake rate at low and moderate circumfluence, APA increased with a decrease of the cellular P quota (Qp)...
February 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28221077/stanley-stan-kuczaj-ii-1950-2016
#3
Jennifer Vonk
Presents an obituary for Stanley (Stan) Kuczaj II who passed away suddenly on April 14, 2016 at the age of 65 in his home in Hattiesburg Mississippi. The field of comparative cognition and animal behavior lost a leader, a friend, and a mentor that day. At the time of his passing, Stan was a fellow and the president of the Society for Comparative Psychology and Behavioral Neuroscience, Division 6, of the American Psychological Association (APA). He was also a fellow of the American Association for the Advancement of Science, APA's Divisions 3 and 7, and the Psychonomic Society...
February 2017: American Psychologist
https://www.readbyqxmd.com/read/28221076/lorraine-williams-greene-1950-2016
#4
Guy Seymour, Adrienne Bradford
Presents an obituary for Lorraine Williams Greene who died on February 25, 2016. Lorraine started her professional career as a school psychologist for the Atlanta Public Schools. For the rest of her life, she was involved in her community through her church, her sorority, the Coalition of One Hundred Black Women, and other national and local service organizations. Within the American Psychological Association (APA), Lorraine was active in Division 18, Psychologists in Public Service, first as Chair of the Police and Public Safety Section, then as the division's representative to APA Council, and, in 2016, as President-elect of the Division...
February 2017: American Psychologist
https://www.readbyqxmd.com/read/28221067/ethical-concerns-for-telemental-health-therapy-amidst-governmental-surveillance
#5
Samuel D Lustgarten, Alexander J Colbow
Technology, infrastructure, governmental support, and interest in mental health accessibility have led to a burgeoning field of telemental health therapy (TMHT). Psychologists can now provide therapy via computers at great distances and little cost for parties involved. Growth of TMHT within the U.S. Department of Veterans Affairs and among psychologists surveyed by the American Psychological Association (APA) suggests optimism in this provision of services (Godleski, Darkins, & Peters, 2012; Jacobsen & Kohout, 2010)...
February 2017: American Psychologist
https://www.readbyqxmd.com/read/28221065/the-american-psychological-association-task-force-assessment-of-violent-video-games-science-in-the-service-of-public-interest
#6
Sandra L Calvert, Mark Appelbaum, Kenneth A Dodge, Sandra Graham, Gordon C Nagayama Hall, Sherry Hamby, Lauren G Fasig-Caldwell, Martyna Citkowicz, Daniel P Galloway, Larry V Hedges
A task force of experts was convened by the American Psychological Association (APA) to update the knowledge and policy about the impact of violent video game use on potential adverse outcomes. This APA Task Force on Media Violence examined the existing literature, including the meta-analyses in the field, since the last APA report on media violence in 2005. Because the most recent meta-analyses were published in 2010 and reflected work through 2009, the task force conducted a search of the published studies from 2009-2013...
February 2017: American Psychologist
https://www.readbyqxmd.com/read/28220064/effect-of-experimentally-induced-trunk-muscular-tensions-on-the-sit-to-stand-task-performance-and-associated-postural-adjustments
#7
Alain Hamaoui, Caroline Alamini-Rodrigues
It has been shown that increased muscular activity along the trunk is likely to impair body balance, but there is little knowledge about its consequences on more dynamic tasks. The purpose of this study was to determine the effect of unilateral and bilateral increases of muscular tension along the trunk on the sit-to-stand task (STS) performance and associated anticipatory postural adjustments (APAs). Twelve healthy females (23 ± 3 years, 163 ± 0.06 cm, 56 ± 9 kg), free of any neurological or musculoskeletal disorders, performed six trials of the STS at maximum speed, in seven experimental conditions varying the muscular tension along each side of the trunk, using a specific bimanual compressive load paradigm...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28219207/-mutations-of-vitamin-d-receptor-gene-found-in-patients-with-multiple-myeloma
#8
Y Liu, H B Rui
Objective: To explore the mutations of vitamin D receptor (VDR) gene in patients with multiple myeloma (MM). Methods: Polymerase chain reaction (PCR) and direct DNA sequencing were used to detect the mutations of VDR gene(loci Fok Ⅰ, Bsm Ⅰ, Apa Ⅰ, Taq Ⅰ) in forty MM cases and 84 healthy control subjects. Results: A synonymous mutation (ATC→ATA , both encode isoleucine) at cDNA codon1421 of VDR gene was found in one MM patients, which correlated to a better therapeutic response. Rare Bsm Ⅰ AA genotype and Taq Ⅰ CC genotype were detected in a MM patient, which might be related to the relapsing and refracfory disease...
February 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28216725/autoantibodies-other-than-anti-desmogleins-in-pemphigus-vulgaris-patients
#9
Marwah Adly Saleh, Hedayat Salem, Hoda El Azizy
BACKGROUND: Pemphigus vulgaris (PV) is an immunoglobulin G-mediated autoimmune bullous skin disease. Nonorgan-specific antibodies were detected in Tunisian and Brazilian pemphigus patients with different prevalence. MATERIALS AND METHODS: Fifty PV patients and fifty controls were screened for antinuclear antibodies (ANAs), anti-smooth muscle antibodies (ASMAs), anti-parietal antibodies (APAs), anti-mitochondrial antibodies, and Anti-nuclear cytoplasmic antibodies (ANCA) by indirect immunofluorescence...
January 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28213690/anticipatory-postural-adjustments-associated-with-reaching-movements-are-programmed-according-to-the-availability-of-visual-information
#10
Roberto Esposti, Carlo Bruttini, Francesco Bolzoni, Paolo Cavallari
During goal-directed arm movements, the eyes, head, and arm are coordinated to look at and reach the target. We examined whether the expectancy of visual information about the target modifies Anticipatory Postural Adjustments (APAs). Ten standing subjects had to (1) move the eyes, head and arm, so as to reach, with both gaze and index-finger, a target of known position placed outside their visual field (Gaze-Reach); (2) look at the target while reaching it (Reach in Full Vision); (3) keep the gaze away until having touched it (Reach then Gaze) and (4) just Gaze without Reach the target...
February 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28213233/silver-nanoclusters-catalyzed-luminol-chemiluminescence-for-hydrogen-peroxide-and-uric-acid-detection
#11
Yingying Sheng, Hongli Yang, Ying Wang, Lu Han, Yanjun Zhao, Aiping Fan
In the present study, four kinds of bovine serum albumin (BSA) caped silver nanoclusters (Ag NCs) were prepared using different amount of BSA as template, respectively. The diameters of the four prepared BSA-Ag NCs were all less than 4nm which were obtained using high-resolution transmission electron microscopy (HRTEM). All of the BSA-Ag NCs showed catalytic activity in luminol-H2O2 chemiluminescent (CL) reaction. It was interesting that different CL kinetic curves were obtained in different BSA-Ag NCs catalyzed CL reaction...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28208816/posttraumatic-stress-disorder-in-the-dsm-5-controversy-change-and-conceptual-considerations
#12
REVIEW
Anushka Pai, Alina M Suris, Carol S North
The criteria for posttraumatic stress disorder PTSD have changed considerably with the newest edition of the American Psychiatric Association's (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Changes to the diagnostic criteria from the DSM-IV to DSM-5 include: the relocation of PTSD from the anxiety disorders category to a new diagnostic category named "Trauma and Stressor-related Disorders", the elimination of the subjective component to the definition of trauma, the explication and tightening of the definitions of trauma and exposure to it, the increase and rearrangement of the symptoms criteria, and changes in additional criteria and specifiers...
February 13, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28202497/deficiency-of-the-angiotensinase-aminopeptidase-a-increases-susceptibility-to-glomerular-injury
#13
Juan Carlos Q Velez, Ehtesham Arif, Jessalyn Rodgers, Megan P Hicks, John M Arthur, Deepak Nihalani, Evelyn T Bruner, Milos N Budisavljevic, Carl Atkinson, Wayne R Fitzgibbon, Michael G Janech
Aminopeptidase A (APA) is expressed in glomerular podocytes and tubular epithelia and metabolizes angiotensin II (AngII), a peptide known to promote glomerulosclerosis. In this study, we tested whether APA expression changes in response to progressive nephron loss or whether APA exerts a protective role against glomerular damage and during AngII-mediated hypertensive kidney injury. At advanced stages of FSGS, fawn-hooded hypertensive rat kidneys exhibited distinctly increased APA staining in areas of intact glomerular capillary loops...
February 15, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28202357/variations-in-the-arterial-blood-supply-to-the-penis-and-the-accessory-pudendal-artery-a-meta-analysis-and-review-of-its-implications-in-radical-prostatectomy
#14
Brandon Michael Henry, Przemysław A Pękala, Jens Vikse, Beatrice Sanna, Bendik Skinningsrud, Karolina Saganiak, Jerzy A Walocha, Krzysztof A Tomaszewski
PURPOSE: The aim of this meta-analysis was to analyze the available literature and provide comprehensive data on the prevalence and variations of accessory pudendal artery (APA) and the three types of penile blood supply (Type 1 - internal pudendal artery (IPA) only, Type 2 - IPA and APA), Type 3 - APA only) MATERIALS AND METHODS: We conducted an extensive search of the major databases and identified 23 studies (4,945 patients) suitable for inclusion in this meta-analysis. Studies eligible for inclusion included cadaveric, imaging or intraoperative studies...
February 12, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28192866/the-importance-of-medial-lateral-styloid-process-angulation-coronal-plane-angle-in-symptomatic-eagle-syndrome
#15
Veysel Burulday, Mehmet Hüseyin Akgül, Nuray Bayar Muluk, Burak Yağdıran, Mikail Inal
OBJECTIVES: We used three-dimensional computerized tomography (3DCT) to obtain images of Eagle Syndrome (ES) cases and measurements of relevant variables. METHODS: Twenty-five subjects with ES and 25 controls were included in this retrospective study. Styloid process length, anterior-posterior styloid process angulation (Sagittal plane angle) (APA), medial-lateral styloid process angulation (Coronal plane angle) (MLA), tonsil-stiloid distance and carotid-stiloid distance were measured on CT and 3DCT images, and cranial and neck angiography was obtained, from a total of 580 images...
February 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28190776/regulators-of-alternative-polyadenylation-operate-at-the-transition-from-mitosis-to-meiosis
#16
Lingjuan Shan, Chan Wu, Di Chen, Lei Hou, Xin Li, Lixia Wang, Xiao Chu, Yifeng Hou, Zhaohui Wang
In the sexually reproductive organisms, gametes are produced by meiosis following a limited mitotic amplification. However, the intrinsic program switching cells from mitotic to meiotic cycle is unclear. Alternative polyadenylation (APA) is a highly conserved means of gene regulation and is achieved by the RNA 3'-processing machinery to generate diverse 3'UTR profiles. In Drosophila spermatogenesis, we observed distinct profiles of transcriptome-wide 3'UTR between mitotic and meiotic cells. In mutant germ cells stuck in mitosis, 3'UTRs of hundreds of genes were consistently shifted...
January 27, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28185793/establishment-of-an-adjusted-prognosis-analysis-model-for-initially-diagnosed-non-small-cell-lung-cancer-with-brain-metastases-from-sun-yat-sen-university-cancer-center
#17
Xiao-Xiao Dinglin, Shu-Xiang Ma, Fang Wang, De-Lan Li, Jian-Zhong Liang, Xin-Ru Chen, Qing Liu, Yin-Duo Zeng, Li-Kun Chen
BACKGROUND: The current published prognosis models for brain metastases (BMs) from cancer have not addressed the issue of either newly diagnosed non-small-cell lung cancer (NSCLC) with BMs or the lung cancer genotype. We sought to build an adjusted prognosis analysis (APA) model, a new prognosis model specifically for NSCLC patients with BMs at the initial diagnosis using adjusted prognosis analysis (APA). PATIENTS AND METHODS: The model was derived using data from 1158 consecutive patients, with 837 in the derivation cohort and 321 in the validation cohort...
January 13, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28183635/mineralization-potential-of-cellulose-nanofibrils-reinforced-gelatine-scaffolds-for-promoted-calcium-deposition-by-mesenchymal-stem-cells
#18
Selestina Gorgieva, Lenart Girandon, Vanja Kokol
Cellulose-nanofibrils (CNFs) enriched gelatine (GEL) scaffolds were fabricated in-situ by the combined freeze-thawing process and carbodiimide crosslinking chemistry. The original- and variously surface anionised CNFs (carboxylated/CNF-COOH/, and phosphonated with 3-AminoPropylphosphoric Acid/CNF-COOH-ApA/) were used in order to tune the scaffolds' biomimetic structure towards a more intensive mineralization process. The pore size reduction (from 208±35μm to 91±35μm) after 50% v/v of CNFs addition to GEL was identified, while separated pore-walls' alignment vs...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28177885/aminopeptidase-a-initiates-tumorigenesis-and-enhances-tumor-cell-stemness-via-twist1-upregulation-in-colorectal-cancer
#19
Hui-Yu Chuang, Jeng-Kae Jiang, Muh-Hwa Yang, Hsei-Wei Wang, Ming-Chun Li, Chan-Yen Tsai, Yau-Yun Jhang, Jason C Huang
Metastasis accounts for the high mortality rate associated with colorectal cancer (CRC), but metastasis regulators are not fully understood. To identify a novel gene involved in tumor metastasis, we used oligonucleotide microarrays, transcriptome distance analyses, and machine learning algorithms to determine links between primary and metastatic colorectal cancers. Aminopeptidase A (APA; also known as ENPEP) was selected as our focus because its relationship with colorectal cancer requires clarification. Higher APA mRNA levels were observed in patients in advanced stages of cancer, suggesting a correlation between ENPEP and degree of malignancy...
February 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28174624/sex-differences-in-the-aging-pattern-of-renin-angiotensin-system-serum-peptidases
#20
A Fernández-Atucha, A Izagirre, A B Fraile-Bermúdez, M Kortajarena, G Larrinaga, P Martinez-Lage, E Echevarría, J Gil
BACKGROUND: Serum peptidases, such as angiotensin-converting enzyme (ACE), angiotensin-converting enzyme-2 (ACE2), neutral endopeptidase (NEP), aminopeptidase N (APN), and aminopeptidase A (APA), are important elements of the renin-angiotensin system (RAS). Dysregulation of these enzymes has been associated with hypertension and cardiovascular risk. In the present study, serum activities of RAS peptidases were analyzed to evaluate the existence of sexual differences, with a possible different pattern in pre- and post-andropausal/post-menopausal participants...
2017: Biology of Sex Differences
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