keyword
MENU ▼
Read by QxMD icon Read
search

Arthritis juvenile

keyword
https://www.readbyqxmd.com/read/28921906/outcomes-of-severe-uveitic-glaucoma-treated-with-baerveldt-implant-can-blindness-be-prevented
#1
Annelie N Tan, Michiel F Cornelissen, Carroll A B Webers, Roel J Erckens, Tos T J M Berendschot, Henny J M Beckers
PURPOSE: To evaluate long-term outcomes on efficacy and safety of severe uveitic glaucoma treated with a Baerveldt glaucoma implant (BGI). METHODS: A retrospective study of 47 eyes of 47 patients with uveitic glaucoma treated by a BGI between September 2002 and September 2015. Main outcome measures were intraocular pressure (IOP), number of glaucoma medications, course of the uveitis, visual acuity (VA) and complications. RESULTS: Mean IOP dropped from 30...
September 18, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28917219/reuma-pt-contribution-to-the-knowledge-of-immune-mediated-systemic-rheumatic-diseases
#2
Maria José Santos, Helena Canhão, Ana Filipa Mourão, Filipa Oliveira Ramos, Cristina Ponte, Cátia Duarte, Anabela Barcelos, Fernando Martins, José António Melo Gomes
Patient registries are key instruments aimed at a better understanding of the natural history of diseases, at assessing the effectiveness of therapeutic interventions, as well as identifying rare events or outcomes that are not captured in clinical trials. However, the potential of registries goes far beyond these aspects. For example, registries promote the standardization of clinical practice, can also provide information on domains that are not routinely collected in clinical practice and can support decision-making...
September 14, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28916663/erratum-how-common-is-clinically-inactive-disease-in-a-prospective-cohort-of-patients-with-juvenile-idiopathic-arthritis-the-importance-of-definition
#3
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28916545/serologic-evidence-of-gut-driven-systemic-inflammation-in-juvenile-idiopathic-arthritis
#4
Lampros Fotis, Nurmohammad Shaikh, Kevin W Baszis, Charles M Samson, Raffi Lev-Tzion, Anthony R French, Phillip I Tarr
OBJECTIVE: Accumulating evidence links juvenile idiopathic arthritis (JIA) to nonhost factors such as gut microbes. We hypothesize that children with new-onset JIA have increased intestinal bacterial translocation and circulating lipopolysaccharide (LPS). METHODS: We studied systemic treatment-naive patients with JIA [polyarticular JIA, n = 22, oligoarticular JIA, n = 31, and spondyloarthropathies (SpA), n = 16], patients with established inflammatory bowel disease-related arthritis (IBD-RA, n = 11), and 34 healthy controls...
September 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28916542/comparative-effectiveness-of-tumor-necrosis-factor-agents-and-disease-modifying-antirheumatic-therapy-in-children-with-enthesitis-related-arthritis-the-first-year-after-diagnosis
#5
Pamela F Weiss, Rui Xiao, Timothy G Brandon, Ilaria Pagnini, Tracey B Wright, Timothy Beukelman, Esi Morgan-DeWitt, Chris Feudtner
OBJECTIVE: To characterize the effect of anti-tumor necrosis factor (TNF) therapy compared to conventional synthetic disease-modifying antirheumatic drugs (csDMARD) in children with enthesitis-related arthritis (ERA) over the first year after diagnosis. METHODS: We conducted a multicenter retrospective comparative effectiveness study of children diagnosed with ERA. We estimated the effect of anti-TNF therapy on clinical variables (active joint count, tender entheses count) and patient-reported pain and global assessment of disease activity over the first year after diagnosis using state-of-the-art comparative effectiveness analytic methods...
September 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28913656/new-insights-into-cardiac-involvement-in-juvenile-scleroderma-a-three-dimensional-echocardiographic-assessment-unveils-subclinical-ventricle-dysfunction
#6
Reyhan Dedeoglu, Amra Adroviç, Funda Oztunç, Sezgin Sahin, Kenan Barut, Ozgur Kasapcopur
Cardiac manifestations in juvenile scleroderma or systemic sclerosis (JSSc) have poor prognosis, begin in early stages of the disease, and remain clinically asymptomatic. New echocardiography modalities, such as 2D/3D speckle tracking (STE, strain analysis for regional and global ventricular functions), can detect cardiac involvement in early stages. We assessed 21 JSSc patients and 19 controls using 2D/3D STE. The left ventricular end diastolic volume, end systolic volume, and ejection fraction of the patient and control groups were significantly different (99...
September 14, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28911961/sociocultural-considerations-in-juvenile-arthritis-a-review
#7
REVIEW
Kimberly A Lewis, Sharon A Brown, Stefano Tiziani, Ruy Carrasco
PROBLEM: Juvenile Arthritis (JA) is one of the most common autoimmune diseases in children. A variety of sociocultural factors that influence health outcomes in children with JA have been examined in previous research. However, clinical guidelines to guide the care of these children lack support because this research has not been systematically examined and synthesized. ELIGIBILITY CRITERIA: Primary research articles from five internet databases were included if they were peer-reviewed articles in English of studies conducted in the U...
September 11, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28906090/multiple-keratoacanthoma-centrifugum-marginatum-associated-with-juvenile-idiopathic-arthritis-and-persistent-corneal-epithelial-defect-an-unusual-case
#8
Hamid R Jahadi Hosseini, Farhad Handjani, Hamid R Anvari Ardakani, Maryam S Sadati, Mohammad R Khalili, Adel Attarzadeh
We report here a case of a child with multiple keratoacanthoma centrifugum marginatum in association with corneal epithelial defect and juvenile arthritis. Keratoacanthoma is a skin tumor and the patient presented with an uncommon type of it.
October 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28900629/siae-rare-variants-in-juvenile-idiopathic-arthritis-and-primary-antibody-deficiencies
#9
Eirini Sevdali, Elena Tsitsami, Maria Tsinti, Evangelia Farmaki, Efimia Papadopoulou-Alataki, Anastasios E Germenis, Matthaios Speletas
Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare heterozygous loss-of-function mutations in SIAE gene in common autoimmune diseases, including juvenile idiopathic arthritis (JIA), yielded inconsistent results. Considering the distinct pathogenesis of the two main subtypes of JIA, autoinflammatory systemic (sJIA) and autoimmune oligo/polyarticular (aJIA), and a predisposition to autoimmunity displayed by patients and families with primary antibody deficiencies (PADs), the aim of our study was to analyze whether SIAE rare variants are associated with both the phenotype of JIA and the autoimmunity risk in families with PADs...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28887050/genome-engineering-for-personalized-arthritis-therapeutics
#10
REVIEW
Shaunak S Adkar, Jonathan M Brunger, Vincent P Willard, Chia-Lung Wu, Charles A Gersbach, Farshid Guilak
Arthritis represents a family of complex joint pathologies responsible for the majority of musculoskeletal conditions. Nearly all diseases within this family, including osteoarthritis, rheumatoid arthritis, and juvenile idiopathic arthritis, are chronic conditions with few or no disease-modifying therapeutics available. Advances in genome engineering technology, most recently with CRISPR-Cas9, have revolutionized our ability to interrogate and validate genetic and epigenetic elements associated with chronic diseases such as arthritis...
September 5, 2017: Trends in Molecular Medicine
https://www.readbyqxmd.com/read/28884897/shedding-light-on-alopecia-areata-in-pediatrics-a-retrospective-analysis-of-comorbidities-in-children-in-the-national-alopecia-areata-registry
#11
Jennifer Sorrell, Lynn Petukhova, Rachel Reingold, Angela Christiano, Maria Garzon
Alopecia areata (AA) is a common autoimmune disease and it is challenging to predict which patients will have severe disease. The purpose of this retrospective study was to identify comorbidities in children enrolled in the National Alopecia Areata Registry. Atopic dermatitis was more common in patients with severe AA than in those with mild disease. The most common autoimmune comorbidities were vitiligo, psoriasis, thyroid disease, and juvenile idiopathic arthritis.
September 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28871670/-early-detection-of-endothelial-dysfunction-in-children-with-autoimmune-diseases-by-a-novel-noninvasive-technique
#12
Liron Borenstein-Levin, Riva Brik, Giora Pillar, Yonatan Butbul Aviel
INTRODUCTION: Atherosclerosis is emerging as one of the most important causes of morbidity and mortality among patients with different rheumatologic disease. Endothelial dysfunction may be an early sign of atherosclerosis. OBJECTIVES: To evaluate the occurrence of endothelial dysfunction in children with autoimmune diseases, including juvenile idiopathic arthritis (JIA), systemic lupus erythematosus (SLE) and dermatomyositis, using a novel noninvasive technique...
July 2017: Harefuah
https://www.readbyqxmd.com/read/28870142/validation-of-the-standardized-universal-pain-evaluations-for-rheumatology-providers-for-children-and-youth-super-kidz
#13
Nadia J Luca, Jennifer N Stinson, Brian M Feldman, Susanne M Benseler, Dorcas Beaton, Sarah Campillo, Claire LeBlanc, Margaret van Wyk, Ahmed M Bayoumi
Study Design Longitudinal observational clinimetric study with repeated measures. Background No validated multi-dimensional pain measure for children and youth with juvenile idiopathic arthritis (JIA) exists. Objectives To determine the test-retest reliability, construct validity, and responsiveness of English and French versions of the Standardized Universal Pain Evaluations for Rheumatology Providers for Children and Youth (SUPER-KIDZ). Methods Measurement properties of SUPER-KIDZ (older child, younger child, and parent versions) were prospectively evaluated in patients aged 4-18 years with JIA at 2 centres...
September 4, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28865469/comics-as-an-educational-tool-for-children-with-juvenile-idiopathic-arthritis
#14
Amir Mendelson, Noa Rabinowicz, Yonit Reis, Gil Amarilyo, Liora Harel, Philip J Hashkes, Yosef Uziel
BACKGROUND: This study examined whether the comic book Neta and the Medikidz Explain JIA would improve disease-related knowledge and treatment adherence among patients with juvenile idiopathic arthritis (JIA). METHODS: In this prospective cohort study, JIA patients answered 20 multiple-choice knowledge questions about their disease, before and after reading the comic book. Demographic, clinical, health-related quality of life and adherence data were recorded and correlated to the responses...
September 2, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28864647/isolated-arthritis-of-the-temporomandibular-joint-as-the-initial-manifestation-of-juvenile-idiopathic-arthritis
#15
Boris Hügle, Lynn Spiegel, Julia Hotte, Stefan Wiens, Troels Herlin, Randy Q Cron, Matthew L Stoll, Surabhi Vinod, Peter Stoustrup, Thomas Klit Pedersen, Marinka Twilt
OBJECTIVE: To describe characteristics of patients with juvenile idiopathic arthritis (JIA) presenting with isolated arthritis of the temporomandibular joints (TMJ). METHODS: Patients with JIA with isolated TMJ arthritis from 4 large tertiary pediatric rheumatology centers were included. Demographic and clinical data were analyzed using descriptive statistics. RESULTS: Fifty-five patients were identified (65% bilateral presentation). Six patients developed arthritis in other joints (median time 6 mos); 4 patients developed uveitis, all prior to arthritis...
September 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28861733/patterns-of-uveitis-in-children-at-the-apex-institute-for-eye-care-in-india-analysis-and-review-of-literature
#16
Brijesh Takkar, Pradeep Venkatesh, Nripen Gaur, Sat Pal Garg, Rajpal Vohra, Supriyo Ghose
AIM: To study patterns of uveitis in Indian children and compare with data sets published earlier in the literature. METHODS: Consecutive patients below 16 years of age presenting to the uvea clinic of a tertiary eye care center were included prospectively through the period of July 2009-August 2013. Children with retinal vasculitis, exogenous endophthalmitis and masquerade syndromes were excluded from analysis. Uveitis was classified as per the nomenclature system adopted by the International Uveitis Study Group...
August 31, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28861674/-ocular-involvement-in-rheumatoid-arthritis-connective-tissue-diseases-and-vasculitis
#17
REVIEW
I Kötter, N Stübiger, C Deuter
There are many interfaces between ophthalmologists and rheumatologists. On the one hand ophthalmologists face the question if an inflammation of the eye is caused by systemic inflammatory rheumatic diseases and on the other hand rheumatologists have to consider that ocular manifestations are relatively common in some inflammatory rheumatic diseases. Furthermore, these ocular manifestations may influence therapeutic decisions of the rheumatologist. This article summarizes which ocular inflammations can be associated with rheumatoid arthritis, connective tissue diseases and vasculitides...
August 31, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28861079/tocilizumab-contributes-to-the-inflammatory-status-of-mature-dendritic-cells-through-interleukin-6-receptor-subunits-modulation
#18
Daniel Meley, Audrey Héraud, Valerie Gouilleux-Gruart, Fabrice Ivanes, Florence Velge-Roussel
Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other inflammatory diseases in close future. Dendritic cells (DCs) appear to be deeply involved in the immunopathology of these diseases, yet the effects of tocilizumab on these cells were poorly studied. In this study, we explored the effect of tocilizumab on the regulation of IL-6R subunits [gp130, soluble form of IL-6Rα (sIL-6Rα), and mIL-6Rα] in human monocyte-derived DCs...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28860338/hif1a-is-a-critical-downstream-mediator-for-hemophagocytic-lymphohistiocytosis
#19
Rui Huang, Yoshihiro Hayashi, Xiaomei Yan, Jiachen Bu, Jieyu Wang, Yue Zhang, Yile Zhou, Yuting Tang, Lingyun Wu, Zefeng Xu, Xin Liu, Qianfei Wang, Jianfeng Zhou, Zhijian Xiao, James P Bridges, Rebecca A Marsh, Kejian Zhang, Michael B Jordan, Yuhua Li, Gang Huang
Hemophagocytic lymphohistiocytosis is a life-threatening syndrome characterized by overwhelming immune activation. A steroid and chemotherapy-based regimen remains as the first-line of therapy but it has substantial morbidity. Thus, novel, less toxic therapy for hemophagocytic lymphohistiocytosis is urgently needed. Although differences exist between familial hemophagocytic lymphohistiocytosis and secondary hemophagocytic lymphohistiocytosis, they have many common features. Using bioinformatic analysis with familial hemophagocytic lymphohistiocytosis and systemic juvenile idiopathic arthritis, which is associated with secondary hemophagocytic lymphohistiocytosis, we identified a common hypoxia-inducible factor 1A (HIF1A) signature...
August 31, 2017: Haematologica
https://www.readbyqxmd.com/read/28858208/inflammatory-diseases-and-growth-effects-on-the-gh-igf-axis-and-on-growth-plate
#20
REVIEW
Francesca Cirillo, Pietro Lazzeroni, Chiara Sartori, Maria Elisabeth Street
This review briefly describes the most common chronic inflammatory diseases in childhood, such as cystic fibrosis (CF), inflammatory bowel diseases (IBDs), juvenile idiopathic arthritis (JIA), and intrauterine growth restriction (IUGR) that can be considered, as such, for the changes reported in the placenta and cord blood of these subjects. Changes in growth hormone (GH) secretion, GH resistance, and changes in the insulin-like growth factor (IGF) system are described mainly in relationship with the increase in nuclear factor-κB (NF-κB) and pro-inflammatory cytokines...
August 31, 2017: International Journal of Molecular Sciences
keyword
keyword
73049
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"