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sarcoidosis guidelines

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https://www.readbyqxmd.com/read/27894280/is-there-any-association-between-sarcoidosis-and-infectious-agents-a-systematic-review-and-meta-analysis
#1
Tiago Esteves, Gloria Aparicio, Vicente Garcia-Patos
BACKGROUND: During the last few years, investigators have debated the role that infectious agents may have in sarcoidosis pathogenesis. With the emergence of new molecular biology techniques, several studies have been conducted; therefore, we performed a meta-analysis in order to better explain this possible association. METHODS: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement from the Cochrane collaboration guidelines...
November 28, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27836307/early-detection-of-cardiac-involvement-in-sarcoidosis-with-2-dimensional-speckle-tracking-echocardiography
#2
Elie-Dan Schouver, Pamela Moceri, Denis Doyen, Nathalie Tieulie, Viviane Queyrel, Delphine Baudouy, Pierre Cerboni, Pierre Gibelin, Sylvie Leroy, Jean-Gabriel Fuzibet, Emile Ferrari
BACKGROUND/OBJECTIVES: Cardiac sarcoidosis (CS) is associated with high morbidity and sudden death. The absence of specific symptoms and lack of diagnostic gold standard technique is challenging. New imaging methods could improve the diagnosis of CS. The aim of our study was to assess the role of left ventricular (LV) longitudinal and circumferential strain as estimated by 2D speckle-tracking imaging in patients with diagnosed sarcoidosis without cardiac involvement according to the current guidelines...
October 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27795804/hepatic-sarcoidosis-a-case-series
#3
Rym Ennaifer, Shema Ayadi, Hayfa Romdhane, Myriam Cheikh, Houda Ben Nejma, Wassila Bougassas, Najet Bel Hadj
Sarcoidosis is a systemic non caseous granulomas disease. Liver is a common location but usually asymptomatic. Evidence based guidelines for this location treatment is lacking and the effect of corticosteroids may be inadequate. The aim of our study was to describe the clinical, biochemical, radiological and therapeutic features of seven patients with systemic sarcoidosis and liver involvement. A retrospective and descriptive monocentric study, over 3 years, including seven patients with systemic sarcoidosis and liver involvement...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27758984/clinical-features-of-sarcoidosis-in-oman-a-report-from-the-middle-east-region
#4
B Jayakrishnan, Nasser Al-Busaidi, Ahsan Al-Lawati, Jojy George, Omar A Al-Rawas, Yaqoub Al-Mahrouqi, Nabil Al-Lawati
BACKGROUND: Though clinical features of sarcoidosis follow a similar pattern, some heterogeneity is seen in different ethnic and racial groups. OBJECTIVES: To describe for the first time the clinical characteristics of sarcoidosis patients in the Sultanate of Oman. METHODS: The data on all cases of sarcoidosis followed up in the two tertiary hospitals in Oman were retrieved retrospectively. RESULTS: Of the 92 patients, for representing the ethnic data only Omani patients (n=83) were included...
October 7, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/27721933/intra-cardiac-distribution-of-late-gadolinium-enhancement-in-cardiac-sarcoidosis-and-dilated-cardiomyopathy
#5
Makoto Sano, Hiroshi Satoh, Kenichiro Suwa, Masao Saotome, Tsuyoshi Urushida, Hideki Katoh, Hideharu Hayashi, Takeji Saitoh
Cardiac involvement of sarcoid lesions is diagnosed by myocardial biopsy which is frequently false-negative, and patients with cardiac sarcoidosis (CS) who have impaired left ventricular (LV) systolic function are sometimes diagnosed with dilated cardiomyopathy (DCM). Late gadolinium enhancement (LE) in magnetic resonance imaging is now a critical finding in diagnosing CS, and the novel Japanese guideline considers myocardial LE to be a major criterion of CS. This article describes the value of LE in patients with CS who have impaired LV systolic function, particularly the diagnostic and clinical significance of LE distribution in comparison with DCM...
September 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/27663033/a-rare-presentation-of-histologically-proven-sarcoidosis-of-the-knee-a-case-report-and-brief-review-of-the-literature
#6
Evan Deschuyteneer, R Rongé, A Riffi, K De Pierre, F Vandenbroucke, C Boulet, A Goossens, W Vincken
We here report a patient with histologically proven sarcoidosis of the knee, a rare localization of sarcoidosis, which usually presents itself as a pulmonary disease. Case reports of radiological images that suggest osseous sarcoidosis of the appendicular skeleton are not so rare, however few are histologically proven. Since in our patient MRI could not distinguish between sarcoidosis and another (possibly malignant) disease, histological proof was obtained through a CT-guided biopsy. Imaging and treatment guidelines for extrapulmonary sarcoidosis are inexistent, due to lack of randomized trials...
September 23, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27630801/core-measures-for-congestive-heart-failure-in-a-tertiary-care-setting-in-pakistan
#7
Rizwan Zafar, Muhammad Haris, Salman Assad, Muhammad Usman Shabbir, Haider Ghazanfar, Sarah A Malik, Tehreem Khalid, Ali H Abbas, Asad A Saleem
PURPOSE:  Heart failure presents a huge burden for individual patients and the healthcare system as a whole. This study aims to assess the adherence to these core measures as identified by the Joint Commission on Accreditation of Healthcare Organizations (JCAHO)/ American Heart Association (AHA) by physicians of Pakistan. MATERIALS AND METHODOLOGY:  We conducted a cross-sectional study in Shifa International Hospital, Islamabad, Pakistan from the period of April 2013 to April 2016...
August 8, 2016: Curēus
https://www.readbyqxmd.com/read/27613395/isolated-cardiac-sarcoidosis-a-focused-review-of-an-under-recognized-entity
#8
David R Okada, Paco E Bravo, Tomas Vita, Vikram Agarwal, Michael T Osborne, Viviany Taqueti, Hicham Skali, Panithaya Chareonthaitawee, Sharmila Dorbala, Garrick Stewart, Marcelo Di Carli, Ron Blankstein
There is accumulating evidence for the existence of a phenotype of isolated cardiac sarcoidosis (ICS), or sarcoidosis that only involves the heart. In the absence of biopsy-confirmed cardiac sarcoidosis (CS), existing diagnostic criteria require the presence of extra-cardiac sarcoidosis as an inclusion criterion for the diagnosis of CS. Consequently, in the absence of a positive endomyocardial biopsy, ICS is not diagnosable by current guidelines. Therefore, there is uncertainty regarding the epidemiology, pathobiology, clinical characteristics, prognosis, and optimal treatment of ICS...
September 9, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27552344/physical-activity-and-training-in-sarcoidosis-review-and-experience-based-recommendations
#9
Bert Strookappe, Lesley Ann Saketkoo, Marjon Elfferich, Anne Holland, Jolanda De Vries, Ton Knevel, Marjolein Drent
INTRODUCTION: Sarcoidosis is a multisystemic inflammatory disorder with a great variety of symptoms, including fatigue, dyspnea, pain, reduced exercise tolerance and muscle strength. Physical training has the potential to improve exercise capacity and muscle strength, and reduce fatigue. The aim of this review and survey was to present information about the role of physical training in sarcoidosis and offer practical guidelines. AREAS COVERED: A systematic literature review guided an international consensus effort among sarcoidosis experts to establish practice-basic recommendations for the implementation of exercise as treatment for patients with various manifestations of sarcoidosis...
October 2016: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27443438/cardiac-sarcoidosis
#10
REVIEW
David H Birnie, Pablo B Nery, Andrew C Ha, Rob S B Beanlands
Clinically manifest cardiac involvement occurs in perhaps 5% of patients with sarcoidosis. The 3 principal manifestations of cardiac sarcoidosis (CS) are conduction abnormalities, ventricular arrhythmias, and heart failure. An estimated 20% to 25% of patients with pulmonary/systemic sarcoidosis have asymptomatic cardiac involvement (clinically silent disease). In 2014, the first international guideline for the diagnosis and management of CS was published. In patients with clinically manifest CS, the extent of left ventricular dysfunction seems to be the most important predictor of prognosis...
July 26, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27424821/recent-advances-in-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#11
REVIEW
Takahiro Nakajima, Kazuhiro Yasufuku, Taiki Fujiwara, Ichiro Yoshino
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive modality for sampling of mediastinal and hilar lymph nodes as well as pulmonary lesions adjacent to the airway. Guidelines for staging of lung cancer suggest that EBUS-TBNA should be considered the best first test of nodal staging for radiologically abnormal lymph nodes that are accessible by this approach. The application of EBUS-TBNA in pulmonary medicine and thoracic oncology is expanding with its role in the diagnosis of sarcoidosis, lymphoma, and tuberculosis...
July 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27215507/efficacy-of-adalimumab-in-sarcoidosis-patients-who-developed-intolerance-to-infliximab
#12
Heleen A Crommelin, Leone M van der Burg, Adriane D M Vorselaars, Marjolein Drent, Coline H M van Moorsel, Ger T Rijkers, Vera H M Deneer, Jan C Grutters
BACKGROUND: Tumor necrosis factor-alpha (TNF-α) inhibitors are regarded as the third-line therapy in sarcoidosis, the first choice generally being infliximab. To date, data regarding response to adalimumab in sarcoidosis patients intolerant to infliximab are lacking. The objective of this retrospective observational study was to establish if adalimumab could achieve stabilization or improvement of the disease in refractory sarcoidosis patients who developed intolerance to infliximab...
June 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27185993/bronchoalveolar-lavage-cellular-analyses-in-conjunction-with-high-resolution-computed-tomography-imaging-as-a-diagnostic-intervention-for-patients-with-suspected-interstitial-lung-disease
#13
Ammaiyappan Chockalingam, Ranganathan Duraiswamy, Madhavan Jagadeesan
BACKGROUND: Bronchoalveolar lavage (BAL) has gained acceptance for diagnosis of Interstitial lung disease (ILD). The advent of high-resolution computed tomography (HRCT) has reduced the clinical utility of BAL. This work has utilized the recommendations of the American Thoracic Society (ATS) to optimize BAL and the findings have been associated with clinical examination and HRCT to precisely narrow down the cause of ILD. MATERIALS AND METHODS: BAL was performed on ILD suspects at the target site chosen based on HRCT...
May 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27175775/hepatic-sarcoidosis-pathogenesis-clinical-context-and-treatment-options
#14
Umer Syed, Hassan Alkhawam, Mena Bakhit, Rafael A Ching Companioni, Aron Walfish
Sarcoidosis is typically characterized as a non-caseating granulomatous disease that has the ability to affect multiple different organ systems. Although extra-thoracic sarcoidosis can occur in the presence and also without lung involvement, isolated extra-pulmonary disease is rare. The liver is the third most commonly affected organ system after the lungs and lymph nodes. When discussing hepatic sarcoidosis it is important to keep in mind that many patients in this population may not present as one would typically expect since most of the patients are asymptomatic or have mild presentations...
September 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27151523/imaging-of-inflammation-in-unexplained%C3%A2-cardiomyopathy
#15
REVIEW
Ana Kadkhodayan, Panithaya Chareonthaitawee, Subha V Raman, Leslie T Cooper
Myocarditis is a recognized but underdiagnosed cause of cardiomyopathy due to its wide clinical spectrum and nonspecific presentation. Accurate diagnosis is important because 25% of patients with acute myocarditis develop cardiomyopathy, and of those, approximately 5% per year require heart transplantation or die. Current guidelines for the recognition and treatment of the inflammatory cardiomyopathies are limited. The gold standard for diagnosis, endomyocardial biopsy, has low sensitivity, and thus, multimodality imaging of inflammation plays a crucial role in defining the cardiac abnormalities and in assisting with diagnosis and management...
May 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27055839/validation-of-the-king-s-sarcoidosis-questionnaire-ksq-in-a-dutch-sarcoidosis-population
#16
Mirjam J G Van Manen, Monique Wapenaar, Bert Strookappe, Marjolein Drent, Marjon Elfferich, Jolanda de Vries, Harry R Gosker, Surinder S Birring, Amit S Patel, Leon van den Toorn, Bernt van den Blink, Karin Boomars, Elske Hoitsma, Marlies S Wijsenbeek
BACKGROUND: The King's Sarcoidosis Questionnaire (KSQ) is a brief questionnaire assessing health status using five modules (General Health Status, Lung, Eyes, Skin, Medication) in patients with sarcoidosis. The KSQ was only validated in one English sarcoidosis cohort. OBJECTIVE: The aim of this study was to validate the KSQ in a Dutch sarcoidosis population. METHODS: The KSQ was translated according to international guidelines and tested in interviews with patients...
2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/26989819/linear-endobronchial-and-endoesophageal-ultrasound-a-practice-change-in-thoracic-medicine
#17
REVIEW
Peter I Bonta, Laurence Crombag, Jouke T Annema
PURPOSE OF REVIEW: Linear endosonography, including intrathoracic lymph nodal sampling by endobronchial ultrasound with transbronchial needle aspiration (EBUS-TBNA) and endoesophageal ultrasound fine-needle aspiration (EUS-FNA), has an important role in the diagnosing and staging of lung cancer. Furthermore, endosonography is applied in the mediastinal evaluation of sarcoidosis, lymphoma, cysts, and nodal metastases of extrathoracic malignancies. Endosonography-related complications as well as sedation and training strategies are discussed...
May 2016: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/26628758/transbronchial-lung-biopsy-in-patients-with-diffuse-parenchymal-lung-disease-without-idiopathic-pulmonary-fibrosis-pattern-on-hrct-scan-experience-from-a-tertiary-care-center-of-north-india
#18
Girish Sindhwani, Nadia Shirazi, Rakhee Sodhi, Shailendra Raghuvanshi, Jagdish Rawat
BACKGROUND: Diffuse parenchymal lung diseases (DPLD) are a group of disorders characterized by chest radiological findings of bilateral diffuse shadowing. Lung biopsy is generally required to make an etiological diagnosis of DPLD's. Transbronchial lung biopsy (TBLB) is a minimally invasive method to achieve a lung sample which has been found to be a useful diagnostic tool in patients with DPLD. As per American Thoracic Society guidelines for management of idiopathic interstitial pneumonias, TBLB is not required in patients who have findings consistent with idiopathic pulmonary fibrosis (IPF) on HRCT scan thorax...
September 2015: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/26623120/ultrasound-techniques-in-the-evaluation-of-the-mediastinum-part-2-mediastinal-lymph-node-anatomy-and-diagnostic-reach-of-ultrasound-techniques-clinical-work-up-of-neoplastic-and-inflammatory-mediastinal-lymphadenopathy-using-ultrasound-techniques-and-how-to
#19
REVIEW
Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich
Ultrasound imaging has gained importance in pulmonary medicine over the last decades including conventional transcutaneous ultrasound (TUS), endoscopic ultrasound (EUS), and endobronchial ultrasound (EBUS). Mediastinal lymph node (MLN) staging affects the management of patients with both operable and inoperable lung cancer (e.g., surgery vs. combined chemoradiation therapy). Tissue sampling is often indicated for accurate nodal staging. Recent international lung cancer staging guidelines clearly state that endosonography should be the initial tissue sampling test over surgical staging...
October 2015: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/26543620/ultrasound-techniques-in-the-evaluation-of-the-mediastinum-part-i-endoscopic-ultrasound-eus-endobronchial-ultrasound-ebus-and-transcutaneous-mediastinal-ultrasound-tmus-introduction-into-ultrasound-techniques
#20
REVIEW
Christoph Frank Dietrich, Jouke Tabe Annema, Paul Clementsen, Xin Wu Cui, Mathias Maximilian Borst, Christian Jenssen
Ultrasound imaging has gained importance in pulmonary medicine over the last decades including conventional transcutaneous ultrasound (TUS), endoscopic ultrasound (EUS), and endobronchial ultrasound (EBUS). Mediastinal lymph node staging affects the management of patients with both operable and inoperable lung cancer (e.g., surgery vs. combined chemoradiation therapy). Tissue sampling is often indicated for accurate nodal staging. Recent international lung cancer staging guidelines clearly state that endosonography (EUS and EBUS) should be the initial tissue sampling test over surgical staging...
September 2015: Journal of Thoracic Disease
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