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https://www.readbyqxmd.com/read/26294856/turning-nutrition-on-its-head-noakes-gets-his-day
#1
Chris Bateman
No abstract text is available yet for this article.
April 2015: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/26114326/relationships-between-cardiorespiratory-and-muscular-fitness-with-cardiometabolic-risk-in-adolescents
#2
Duncan S Buchan, Lynne M Boddy, John D Young, Stephen-Mark Cooper, Tim D Noakes, Craig Mahoney, Julian P H Shields, Julien S Baker
This study examined the independent relationships between cardiorespiratory and muscular fitness with cardiometabolic risk in adolescents. Subjects were 192 adolescents (118 boys), aged 15-17.5 years. The 2 m multi-stage fitness test assessed cardiorespiratory fitness and the counter movement jump assessed muscular fitness. Additional measures included interleukin-6, C-reactive protein, adiponectin, fibrinogen and plasminogen activator inhibitor-1. Regression analysis revealed that cardiorespiratory fitness was negatively related to cardiometabolic risk (β = -0...
2015: Research in Sports Medicine
https://www.readbyqxmd.com/read/24464269/effect-of-crystallinity-on-electrostatic-charging-in-dry-powder-inhaler-formulations
#3
Jennifer Wong, Philip Chi Lip Kwok, Tim Noakes, Ali Fathi, Fariba Dehghani, Hak-Kim Chan
PURPOSE: This study aimed to characterize inherent charge generated by micron-sized drug-only formulations of amorphous and crystalline salbutamol sulfate (SS). METHODS: Amorphous SS was produced by spray-drying whilst crystalline SS was produced by conditioning spray-dried SS with supercritical CO2 and menthol. Electrostatic charge of the powders was characterized in two ways. Firstly, the charge profile of the aerosols dispersed from an Aerolizer® was measured using a modified Electrostatic Low Pressure Impactor (ELPI™)...
July 2014: Pharmaceutical Research
https://www.readbyqxmd.com/read/23374311/inconvenient-truth-or-public-health-threat
#4
Chris Bateman
For Tim Noakes, the University of Cape Town's 'great centenary debate' on what constitutes a healthy diet was a 'kangaroo court', deliberately set up to discredit the 'inconvenient and threatening truths' behind his relatively recent and much-touted high-fat, no sugar, no carbohydrates eating regimen.
February 2013: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/23134510/identification-of-rna-bound-to-the-tdp-43-ribonucleoprotein-complex-in-the-adult-mouse-brain
#5
Ramesh K Narayanan, Marie Mangelsdorf, Ajay Panwar, Tim J Butler, Peter G Noakes, Robyn H Wallace
Cytoplasmic inclusions containing TDP-43 are a pathological hallmark of several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. TDP-43 is an RNA binding protein involved in gene regulation through control of RNA transcription, splicing and transport. However, the function of TDP-43 in the nervous system is largely unknown and its role in the pathogenesis of ALS is unclear. The aim of this study was to identify genes in the central nervous system that are regulated by TDP-43...
May 2013: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/19876642/evidence-of-increased-electro-mechanical-delay-in-the-left-and-right-ventricle-after-prolonged-exercise
#6
COMPARATIVE STUDY
Fang Chan-Dewar, David Oxborough, Rob Shave, Warren Gregson, Greg Whyte, Tim Noakes, Keith George
We assessed the time delay from the onset of QRS (Q) to peak systolic (S') and diastolic (E') tissue velocities in the left (LV) and right ventricle (RV) before and after prolonged exercise. Nineteen well-trained runners (mean +/- SD age, 41 +/- 9 years) had tissue-Doppler echocardiography performed before and after an 89 km ultra-marathon race. Longitudinal tissue motion was analysed in LV basal and mid-wall segments and RV free wall. Electromechanical coupling was assessed by the delay between Q and S' as well as E' tissue velocities...
February 2010: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/19222048/trauma-pod-a-semi-automated-telerobotic-surgical-system
#7
Pablo Garcia, Jacob Rosen, Chetan Kapoor, Mark Noakes, Greg Elbert, Michael Treat, Tim Ganous, Matt Hanson, Joe Manak, Chris Hasser, David Rohler, Richard Satava
BACKGROUND: The Trauma Pod (TP) vision is to develop a rapidly deployable robotic system to perform critical acute stabilization and/or surgical procedures, autonomously or in a teleoperative mode, on wounded soldiers in the battlefield who might otherwise die before treatment in a combat hospital could be provided. METHODS: In the first phase of a project pursuing this vision, a robotic TP system was developed and its capability demonstrated by performing selected surgical procedures on a patient phantom...
June 2009: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/18928034/jim-peters-collapse-in-the-1954-vancouver-empire-games-marathon
#8
Tim Noakes, Jackie Mekler, Dan Tunstall Pedoe
On 7 August 1954, the world 42 km marathon record holder, Jim Peters, collapsed repeatedly during the final 385 metres of the British Empire and Commonwealth Games marathon held in Vancouver, Canada. It has been assumed that Peters collapsed from heatstroke because he ran too fast and did not drink during the race, which was held in windless, cloudless conditions with a dry-bulb temperature of 28 degrees C. Hospital records made available to us indicate that Peters might not have suffered from exertional heatstroke, which classically produces a rectal temperature > 42 degrees C, cerebral effects and, usually, a fatal outcome without vigorous active cooling...
August 2008: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/18803433/meeting-the-global-demand-of-sports-safety-the-intersection-of-science-and-policy-in-sports-safety
#9
REVIEW
Toomas Timpka, Caroline F Finch, Claude Goulet, Tim Noakes, Kaissar Yammine
Sports and physical activity are transforming, and being transformed by, the societies in which they are practised. From the perspectives of both competitive and non-competitive sports, the complexity of their integration into today's society has led to neither sports federations nor governments being able to manage the safety problem alone. In other words, these agencies, whilst promoting sport and physical activity, deliver policy and practices in an uncoordinated way that largely ignores the need for a concurrent overall policy for sports safety...
2008: Sports Medicine
https://www.readbyqxmd.com/read/18664484/left-ventricular-wall-segment-motion-after-ultra-endurance-exercise-in-humans-assessed-by-myocardial-speckle-tracking
#10
Keith George, Rob Shave, David Oxborough, Tim Cable, Ellen Dawson, Nigel Artis, David Gaze, Tamara Hew-Butler, Karen Sharwood, Tim Noakes
AIMS: Assessment of the left ventricular responses to prolonged exercise has been limited by technology available to assess cardiac tissue movement. Recently developed strain and strain rate imaging provide the unique opportunity to assess tissue deformation in all planes of motion. METHODS AND RESULTS: Nineteen runners (mean+/-SD age; 41+/-9 years) were assessed prior to and within 60 min (34+/-10 min) of race finish (Comrades Marathon, 89 km). Standard echocardiography assessed ejection fraction and the ratio of early to atrial (E/A) peak transmitral blood flow velocities...
March 2009: European Journal of Echocardiography
https://www.readbyqxmd.com/read/17617170/the-effect-of-antecedent-fatiguing-activity-on-the-relationship-between-perceived-exertion-and-physiological-activity-during-a-constant-load-exercise-task
#11
Roger Eston, James Faulkner, Alan St Clair Gibson, Tim Noakes, Gaynor Parfitt
This study assessed the relationship between the rate of change of the rating of perceived exertion (RPE), physiological activity, and time to volitional exhaustion. After completing a graded exercise test, 10 participants cycled at a constant load equating to 75% of peak oxygen uptake (V O(2)peak) to exhaustion. Participants performed two further constant load exercise tests at 75%V O(2)peak in a fresh state condition within the next 7 days. The RPE was regressed against time and percentage of the time (%time) to volitional exhaustion in both conditions...
September 2007: Psychophysiology
https://www.readbyqxmd.com/read/17342885/fluid-guidelines-for-sport-interview-with-professor-tim-noakes-interview-by-louise-m-burke
#12
Tim Noakes
No abstract text is available yet for this article.
December 2006: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/14501315/fluid-replacement-during-marathon-running
#13
Tim Noakes et al.
During endurance exercise, about 75% of the energy produced from metabolism is in the form of heat, which cannot accumulate. The remaining 25% of energy available can be used for movement. As running pace increases, the rate of heat production increases. Also, the larger one's body mass, the greater the heat production at a particular pace. Sweat evaporation provides the primary cooling mechanism for the body, and for this reason athletes are encouraged to drink fluids to ensure continued fluid availability for evaporation and circulatory flow to the tissues...
September 2003: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/12831696/hyponatremia-in-distance-runners-fluid-and-sodium-balance-during-exercise
#14
REVIEW
Tim Noakes
Since its first description in 1985, two opposing theories have evolved to explain the etiology of symptomatic hyponatremia of exercise. The first holds that the condition occurs only in athletes who lose both water and sodium during exercise, and fail to fully replace their sodium losses. The second theory holds that the symptomatic form of this condition occurs in athletes who generate a whole body fluid overload as a result of an excessive fluid intake during prolonged exercise. It is argued that the promotion of the idea that athletes should drink as much as possible during exercise has produced, rather than prevented, the recent increase in the incidence of this condition...
August 2002: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/12656638/the-conscious-perception-of-the-sensation-of-fatigue
#15
REVIEW
Alan St Clair Gibson, Denise A Baden, Mike I Lambert, E Vicki Lambert, Yolande X R Harley, Dave Hampson, Vivienne A Russell, Tim D Noakes
In this review, fatigue is described as a conscious sensation rather than a physiological occurrence. We suggest that the sensation of fatigue is the conscious awareness of changes in subconscious homeostatic control systems, and is derived from a temporal difference between subconscious representations of these homeostatic control systems in neural networks that are induced by changes in the level of activity. These mismatches are perceived by consciousness-producing structures in the brain as the sensation of fatigue...
2003: Sports Medicine
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