keyword
MENU ▼
Read by QxMD icon Read
search

Laser vein

keyword
https://www.readbyqxmd.com/read/29222552/animal-models-of-retinal-vein-occlusion
#1
Meiaad Khayat, Noemi Lois, Michael Williams, Alan W Stitt
Purpose: To provide a comprehensive and current review on the available experimental animal models of retinal vein occlusion (RVO) and to identify their strengths and limitations with the purpose of helping researchers to plan preclinical studies on RVO. Methods: A systematic review of the literature on experimental animal models of RVO was undertaken. Medline, SCOPUS, and Web of Science databases were searched. Studies published between January 1, 1965, and March 31, 2017, and that met the inclusion criteria were reviewed...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29217521/laser-balloon-or-wide-area-circumferential-irrigated-radiofrequency-ablation-for-persistent-atrial-fibrillation-a-multicenter-prospective-randomized-study
#2
Boris Schmidt, Petr Neuzil, Armin Luik, Joaquin Osca Asensi, Jan Wilko Schrickel, Thomas Deneke, Stefano Bordignon, Jan Petru, Matthias Merkel, Lucie Sediva, Annemarie Klostermann, Laura Perrotta, Oscar Cano, K R Julian Chun
BACKGROUND: Pulmonary vein isolation is the cornerstone of ablation for persistent atrial fibrillation (AF). The role of balloon catheters in this patient population remains ill defined. We sought to compare efficacy and safety of the laser balloon (LB) with wide-area circumferential pulmonary vein isolation using irrigated radiofrequency current (RF) ablation and 3-dimensional mapping. METHODS AND RESULTS: In 6 European centers, patients with persistent AF were prospectively randomized...
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29215307/effects-of-intravitreous-sodium-hydrosulfide-on-intraocular-pressure-and-retinopathy-in-ocular-hypertensive-rats
#3
M A Özer, Z Erişgin, S Özen, Y Tekelioğlu, S Takır
We investigated the possible neuroprotectant and intraocular pressure (IOP) lowering effects of intravitreous injection of sodium hydrosulfide (NaSH) in a rodent model of experimental glaucoma. Glaucoma currently is treated by controlling IOP using medications and/or surgery. These methods are not entirely adequate for all patients. We divided 24 rats into three groups. For the control group, the right eye was treated with intravitreous saline. For the glaucoma group, ocular hypertension was induced by photocoagulating three episcleral veins and the limbal plexus of the right eye using an argon laser, then saline was injected into the vitreous of these eyes during the third week...
December 7, 2017: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/29214668/photofrin%C3%A2-photodynamic-therapy-with-intratumor-photosensitizer-injection-provides-similar-tumor-response-while-reducing-systemic-skin-photosensitivity-pilot-murine-study
#4
Timothy M Baran
OBJECTIVES: The goal of this study was to compare tumor response to Photofrin® photodynamic therapy using intravenous and intratumoral injection of photosensitizer. Systemic skin photosensitivity and photosensitizer distribution were also compared between the two delivery methods. METHODS: SCCVII tumors were initiated in the hind legs of female C3H mice and grown to a volume of ∼1,000 mm3 . Photofrin® was delivered intravenously via the tail vein at a concentration of 2 mg/kg or intratumorally at concentrations ranging from 0...
December 7, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29206145/dual-wavelength-laser-speckle-contrast-imaging-dwlsci-improves-chronic-measurement-of-superficial-blood-flow-in-hands
#5
Lingke Zhang, Li Ding, Miao Li, Xiaoli Zhang, Diansan Su, Jie Jia, Peng Miao
Laser speckle contrast imaging (LSCI) has been widely used to determine blood flow and perfusion in biological tissues. The physical model of traditional LSCI ignores the effects of scattering property distribution in relation to speckle correlation time τc and blood flow v, which further results in biased estimation. In this study, we developed a dual-wavelength laser speckle contrast imaging (dwLSCI) method and a portable device for imaging the blood flow and tissue perfusion in human hands. Experimental data showed that dwLSCI could retrieve the vein vasculatures under the surface skin, and it further provided accurate measurements of vein blood flow signals, tissue perfusion signals, and fingertip perfusion signals, which assist with assessments of rehabilitation therapy for stroke patients...
December 5, 2017: Sensors
https://www.readbyqxmd.com/read/29204993/update-on-the-use-of-anti-vegf-intravitreal-therapies-for-retinal-vein-occulsions
#6
Yi Jiang, William F Mieler
The use of anti-vascular endothelial growth factor (VEGF) therapy in ophthalmology has profoundly changed our management and treatment of conditions such as cystoid macular edema, diabetic macular edema, choroidal neovascularization, and other proliferative retinopathies. Although initially used for the treatment of choroidal neovascularization in neovascular age-related macular degeneration, their application has spread rapidly for other indications as their outcomes have often outperformed previously existing treatments...
November 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29199233/inhibition-of-laser-induced-choroidal-neovascularization-by-hematoporphyrin-dimethylether-mediated-photodynamic-therapy-in-rats
#7
Yi-Jia Yan, Lei-Lei Bao, Li-Jun Zhang, Jun Bian, Tai-Shan Hu, Mei-Zhen Zheng, Dan-Ye Chen, Xin-Hai Yu, Zhi-Long Chen
This study aimed to investigate the effect of hematoporphyrin dimethylether (HDME)-mediated photodynamic therapy for laser-induced choroidal neovascularization (CNV) in adult Brown Norway rats. HDME was administered via tail vein at 14 d after the laser photocoagulation, and the rats received irradiance with a laser light at 570 nm at 15 min after injection. CNV was evaluated by fundus photography, fundus fluorescein angiography, optical coherence tomography, and hematoxylin and eosin staining. We found that CNV was occurred at 7 d after photocoagulation and reaching peak activity at 14 d after photocoagulation...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29190824/comparison-of-laser-and-circumlimbal-suture-induced-elevation-of-intraocular-pressure-in-albino-cd-1-mice
#8
Hsin-Hua Liu, Liwei Zhang, Meng Shi, Lu Chen, John G Flanagan
Animal models of ocular hypertension are important tools for glaucoma studies. Both acute transient models and chronic models of ocular hypertension may be useful to investigate specific aspects of neurodegeneration. In this study, we compare the intraocular pressure (IOP) and inner retinal changes induced by 1) laser photocoagulation of both episcleral veins and limbal vessels and 2) circumlimbal suture in CD-1 mice. The suture group is divided into 3 subgroups depending on the level of the immediate IOP spike (acute > 55 mmHg or chronic < 55 mmHg) and time period of monitoring (7 or 28 days)...
2017: PloS One
https://www.readbyqxmd.com/read/29190240/comparing-microperimetric-and-structural-findings-in-patients-with-branch-retinal-vein-occlusion-and-diabetic-macular-edema
#9
Amun Sachdev, Magdalena Edington, Rupal Morjaria, Victor Chong
PURPOSE: To compare retinal sensitivity and central retinal thickness in patients with focal diabetic macular edema (DME) and edema secondary to branch retinal vein occlusion (BRVO). METHODS: In this consecutive, cross-sectional, observational study, patients with either DME or BRVO underwent measurements for best-corrected visual acuity, microperimetry, and spectral domain optical coherence tomography. Retinal thickness and sensitivity were measured using Optos Spectral optical coherence tomography/scanning laser ophthalmoscopy (Optos plc, Dunfermline, Scotland, United Kingdom)...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29185100/spatial-distribution-of-cd115-and-cd11b-cells-and-their-temporal-activation-during-oxygen-induced-retinopathy-in-mice
#10
Claudia Brockmann, Sabrina Dege, Sergio Crespo-Garcia, Norbert Kociok, Tobias Brockmann, Olaf Strauß, Antonia M Joussen
PURPOSE: The model of oxygen-induced retinopathy (OIR) is widely used to analyze pathomechanisms in retinal neovascularization. Previous studies have shown that macrophages (MP) play a key role in vessel formation in OIR, the influence of microglia (MG) having been discussed. The aim of our study was to analyze the spatial and temporal distribution and activation of MP/MG expressing CD115 and CD11b during the process of neovascularization in OIR. METHODS: We used MacGreen mice expressing the green fluorescence protein (GFP) under the promoter for CD115...
November 28, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29179738/laser-modified-titanium-surfaces-enhance-the-osteogenic-differentiation-of-human-mesenchymal-stem-cells
#11
Tatiana A B Bressel, Jana Dara Freires de Queiroz, Susana Margarida Gomes Moreira, Jéssyca T da Fonseca, Edson A Filho, Antônio Carlos Guastaldi, Silvia Regina Batistuzzo de Medeiros
BACKGROUND: Titanium surfaces have been modified by various approaches with the aim of improving the stimulation of osseointegration. Laser beam (Yb-YAG) treatment is a controllable and flexible approach to modifying surfaces. It creates a complex surface topography with micro and nano-scaled patterns, and an oxide layer that can improve the osseointegration of implants, increasing their usefulness as bone implant materials. METHODS: Laser beam irradiation at various fluences (132, 210, or 235 J/cm2) was used to treat commercially pure titanium discs to create complex surface topographies...
November 28, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29173075/evaluation-of-plasma-growth-factors-vegf-pdgf-egf-ang1-and-ang2-in-patients-with-varicose-veins-before-and-after-treatment-with-endovenous-laser-ablation
#12
Nabil A Al-Zoubi, Rami J Yaghan, Tagleb S Mazahreh, Emad M Hijazi, Ahmad Alqudah, Yasmin N Owaisy, Shadi Hamouri, Nawaf J Al-Shatnawi
OBJECTIVE: To measure pre- and postoperative plasma concentrations of growth factors (VEGF, PDGF, EGF, ANG1, and ANG2) in patients with primary lower limb varicose veins (VVs) treated with endovenous laser ablation (EVLA). BACKGROUND: Many studies have explored the potential relationship between primary VVs and growth factors. No previous studies were done for patients treated with EVLA. MATERIALS AND METHODS: Blood samples were obtained from 30 patients with primary VVs undergoing treatment with EVLA before and 1 week after treatment...
November 27, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29165327/effects-of-dl-3-n-butylphthalide-on-cerebral-ischemia-infarction-in-rat-model-by-mass-spectrometry-imaging
#13
Run-Zhe Liu, Chao-Xin Fan, Zhi-Lin Zhang, Xin Zhao, Yi Sun, Hui-Hui Liu, Zong-Xiu Nie, Xiao-Ping Pu
Dl-3-n-butylphthalide (NBP) is a drug that is used in the treatment of ischaemic stroke. However, to the best of our knowledge, there are no systematic studies investigating the effects of dl-3-n-butylphtalide on the brain metabolism of small molecules. In this study, we first investigated the effects of dl-3-n-butylphthalide on the spatial distribution of small molecules in the brains of rats with permanent middle cerebral artery occlusion (pMCAO) using matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) imaging...
November 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29148707/versatile-supermolecular-inclusion-complex-based-on-host-guest-interaction-for-targeted-gene-delivery
#14
Yunxia Sun, Jingyi Zhu, Wen-Xiu Qiu, Qi Lei, Si Chen, Xian-Zheng Zhang
A facile and targeted gene delivery system was prepared by conjugating β-cyclodextrin modified polyethylenimine (PEI-CD) and adamantyl peptide (AdGRGDS) based on host-guest interaction. With the rational design between PEI-CD and AdGRGDS, PEI-CD/AdGRGDS gene delivery system showed excellent DNA binding capability, and exhibited good ability to compact DNA into uniform spherical nanoparticles. In vitro luciferase assay showed that gene expression transfected by PEI-CD/AdGRGDS was stronger than that by PEI-CD in HeLa cells, whereas, gene expression transfected by PEI-CD/AdGRGDS and PEI-CD was similar to each other in COS7 cells...
November 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29141184/unrecognized-venous-injuries-after-cardiac-implantable-electronic-device-transvenous-lead-extraction
#15
Khaldoun G Tarakji, Walid Saliba, Danny Markabawi, E Rene Rodriguez, Yoaav Krauthammer, Michael P Brunner, Ayman A Hussein, Bryan Baranowski, Daniel J Cantillon, Mohamed Kanj, Mark Niebauer, Jack Rickard, Thomas Callahan, Mingyuan Shao, David O Martin, Oussama M Wazni, Bruce L Wilkoff, Carmela D Tan
BACKGROUND: Major complication rate of transvenous lead extraction (TLE) is estimated around 1-2.0%. Laceration of the central veins can be fatal. OBJECTIVES: to define the incidence and extent of venous injuries on a microscopic level after TLE and compare it with the incidence of clinically documented events of venous laceration. METHODS: We studied all patients who underwent TLE at our tertiary center within 30 months via a variety of techniques...
November 7, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29109883/nd-yag-laser-photodisruption-for-multilevel-premacular-hemorrhage-due-to-isolated-retinal-venous-macroaneurysm
#16
Kenan Sonmez, Pehmen Y Ozcan
A 55-year-old man presented with sudden deterioration of vision in the right eye. His visual acuity was reduced to hand motion because of a large multilevel premacular hemorrhage. Nd:YAG laser was performed to drain the entrapped hemorrhage under the internal limiting membrane (ILM) and posterior hyaloid face in the macula into the vitreous. Immediately after laser treatment, streaming of red blood cells into the vitreous gel through the perforation site was observed. At the first-month follow-up, BCVA improved to 20/25 and ILM wrinkling was observed at the macula where the preretinal hemorrhage cleared...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29099501/efficacy-and-timing-of-adjunctive-therapy-in-the-anti-vegf-treatment-regimen-for-macular-oedema-in-retinal-vein-occlusion-12-month-real-world-result
#17
P L Lip, P Cikatricis, A Sarmad, E M Damato, R Chavan, A Mitra, S Elsherbiny, Y Yang, B Mushtaq
PurposeVarious combination treatment regimens have been tried to improve the short-term efficacy of intravitreal monotherapy for the treatment of macular oedema (MO) secondary to retinal vein occlusion (RVO). Our study introduces the RandOL protocol (Ranibizumab and Ozurdex with Laser photocoagulation) of initial anti-VEGF therapy, controlling recurrent non-ischaemic MO with an intravitreal steroid and applying laser therapy to non-perfused retina. We describe our 12-month follow-up experience on timing for adjunctive therapy and real-world effectiveness and safety data...
November 3, 2017: Eye
https://www.readbyqxmd.com/read/29098298/photocoagulation-of-the-retinal-nonperfusion-area-prevents-the-expression-of-the-vascular-endothelial-growth-factor-in-an-animal-model
#18
Makoto Gozawa, Yoshihiro Takamura, Seiji Miyake, Takehiro Matsumura, Masakazu Morioka, Yutaka Yamada, Masaru Inatani
Purpose: The purpose of this study was to evaluate whether photocoagulation of the retinal nonperfusion area suppresses ocular vascular endothelial growth factor (VEGF) expression in a rabbit retinal vein occlusion (RVO) model. Methods: The retinas of pigmented rabbits were made ischemic by a laser on the main branch of retinal veins following intravenous injection of Rose Bengal. The eyes were enucleated before treatment and at 1, 7, and 14 days after laser occlusion...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29097304/laser-responsive-liposome-for-selective-tumor-targeting-of-nitazoxanide-nanoparticles
#19
Wael M Darwish, Noha A Bayoumi, Mohamed T El-Kolaly
Nitazoxanide [2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide], usually referred as NTZ, is an antiparasites drug with a potential anti-cancer reactivity. However, the bioavailability of nitazoxanide is limited due to its poor water solubility. In this study, nitazoxanide could be successfully incorporated in a stable biocompatible liposome (NTZ-LP) using a modified thin film hydration technique. Further, a novel lipophilic phthalocyanine star polymer R4PcZn was prepared as photosensitizer and in situ incorporated with NTZ in the liposome formulation affording a laser-responsive liposome (NTZ-ZnPc-LP)...
October 31, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29097173/effect-of-tumescent-anesthesia-and-patient-positioning-on-laser-tip-junctional-distance-during-endovenous-laser-ablation
#20
Julien Al Shakarchi, Mark Kay, Smilen Kuyumdzhiev, Vasileios Psarros, Radu Rogoveanu, Rajiv Vohra
BACKGROUND: The correct positioning of the laser tip at the saphenofemoral or saphenopopliteal junction during endovenous laser therapy is paramount to ensure a safe and effective procedure. The aim of this study was to demonstrate how patient positioning and tumescence infiltration can affect this safe junctional distance. METHODS: A retrospective review of a prospectively maintained database was carried out for all patients who received endovenous laser treatment for symptomatic varicose veins between February 2008 and February 2014 in one surgeon's practice in a teaching hospital vascular unit...
October 30, 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
keyword
keyword
72993
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"