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Competence

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https://www.readbyqxmd.com/read/28346878/how-appropriate-are-the-english-language-test-requirements-for-non-uk-trained-nurses-a-qualitative-study-of-spoken-communication-in-uk-hospitals
#1
Carole Sedgwick, Mark Garner
BACKGROUND: Non-native speakers of English who hold nursing qualifications from outside the UK are required to provide evidence of English language competence by achieving a minimum overall score of Band 7 on the International English Language Testing System (IELTS) academic test. OBJECTIVES: To describe the English language required to deal with the daily demands of nursing in the UK. To compare these abilities with the stipulated levels on the language test. DESIGN: A tracking study was conducted with 4 nurses, and focus groups with 11 further nurses...
March 6, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28346833/arthroscopic-hip-surgery-in-the-elite-athlete-comparison-of-female-and-male-competitive-athletes
#2
Kotaro R Shibata, Shuichi Matsuda, Marc R Safran
BACKGROUND: Few studies have published the results of hip arthroscopic surgery in elite athletes and none studying a significant number of elite female athletes. PURPOSE: (1) To compare sex-based differences in the ability to return to prior competitive sports activity after arthroscopic hip surgery. (2) To compare sex-based differences in the type of sports activity, diagnosis, and treatment in athletes requiring hip arthroscopic surgery. STUDY DESIGN: Cohort study; Level of evidence, 3...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28346656/7-year-follow-up-after-stereotactic-ablative-radiotherapy-for-patients-with-stage-i-non-small-cell-lung-cancer-results-of-a-phase-2-clinical-trial
#3
Bing Sun, Eric D Brooks, Ritsuko U Komaki, Zhongxing Liao, Melenda D Jeter, Mary F McAleer, Pamela K Allen, Peter A Balter, James D Welsh, Michael S O'Reilly, Daniel Gomez, Stephen M Hahn, Jack A Roth, Reza J Mehran, John V Heymach, Joe Y Chang
BACKGROUND: The authors evaluated the efficacy, patterns of failure, and toxicity of stereotactic ablative radiotherapy (SABR) for patients with medically inoperable, clinical stage I non-small cell lung cancer (NSCLC) in a prospective clinical trial with 7 years of follow-up. Clinical staging was performed according to the seventh edition of the American Joint Committee on Cancer TNM staging system. METHODS: Eligible patients with histologically confirmed NSCLC of clinical stage I as determined using positron emission tomography staging were treated with SABR (50 grays in 4 fractions)...
March 27, 2017: Cancer
https://www.readbyqxmd.com/read/28346623/family-medicine-maternity-care-call-to-action-moving-toward-national-standards-for-training-and-competency-assessment
#4
Susanna R Magee, W Suzanne Eidson-Ton, Larry Leeman, Michael Tuggy, Thomas O Kim, Melissa Nothnagle, Joseph Breuner, Mark Loafman
Maternity care is an integral part of family medicine, and the quality and cost-effectiveness of maternity care provided by family physicians is well documented. Considering the population health perspective, increasing the number of family physicians competent to provide maternity care is imperative, as is working to overcome the barriers discouraging maternity care practice. A standard that clearly defines maternity care competency and a systematic set of tools to assess competency levels could help overcome these barriers...
March 2017: Family Medicine
https://www.readbyqxmd.com/read/28346622/future-of-family-medicine-faculty-development-in-sub-saharan-africa
#5
Paul R Larson, Patrick Chege, Bruce Dahlman, Christine Gibson, Ann Evensen, Maria C Colon-Gonzalez, Stephanie Onguka, Roberta Lamptey, William E Cayley, Bich-May Nguyen, Brian Johnson, Sawra Getnet, Memoona Hasnain
BACKGROUND AND OBJECTIVES: High-quality family medicine education is needed in sub-Saharan Africa to facilitate the future growth of primary care health systems. Current faculty educators recognize the value of dedicated teacher training and ongoing faculty development. However, they are constrained by inadequate faculty development program availability and institutional support. METHODS: A cross-sectional study design was used to conduct a qualitative needs assessment comprised of 37 in-depth, semi-structured interviews of individual faculty trainers from postgraduate family medicine training programs in eight sub-Saharan African countries...
March 2017: Family Medicine
https://www.readbyqxmd.com/read/28346621/current-status-of-family-medicine-faculty-development-in-sub-saharan-africa
#6
Paul R Larson, Patrick Chege, Bruce Dahlman, Christine Gibson, Ann Evensen, Maria C Colon-Gonzalez, Stephanie Onguka, Roberta Lamptey, William E Cayley, Bich-May Nguyen, Brian Johnson, Sawra Getnet, Memoona Hasnain
BACKGROUND AND OBJECTIVES: Reducing the shortage of primary care physicians in sub-Saharan Africa requires expansion of training programs in family medicine. Challenges remain in preparing, recruiting, and retaining faculty qualified to teach in these pioneering programs. Little is known about the unique faculty development needs of family medicine faculty within the sub-Saharan African context. The purpose of this study was to assess the current status and future needs for developing robust family medicine faculty in sub-Saharan Africa...
March 2017: Family Medicine
https://www.readbyqxmd.com/read/28346606/evidence-based-redesign-of-the-comlex-usa-series
#7
John R Gimpel, Dorothy Horber, Jeanne M Sandella, Janice A Knebl, John E Thornburg
To ensure that the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) reflects the evolving practice of osteopathic medicine, the National Board of Osteopathic Medical Examiners has developed new content and format specifications for an enhanced, competency-based examination program to be implemented with COMLEX-USA Level 3 in 2018. This article summarizes the evidence-based design processes that served as the foundation for blueprint development and the evidence supporting its validity...
April 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28346605/does-including-public-health-students-on-interprofessional-teams-increase-attainment-of-interprofessional-practice-competencies
#8
Pamela Ann Duffy, Julie A Ronnebaum, Teri A Stumbo, Kari Nies Smith, Rachel A Reimer
CONTEXT: Interprofessional education (IPE) creates dynamic experiential learning that can address social determinants of health that influence health outcomes. OBJECTIVE: To examine the effects of including public health students on IPE teams on the interprofessional practice domain constructs (values/ethics, roles/responsibilities, interprofessional communication, and teams and teamwork). METHODS: This single-case, mixed-methods study was performed using a grounded theory approach...
April 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28346537/deep-mutational-scanning-identifies-sites-in-influenza-nucleoprotein-that-affect-viral-inhibition-by-mxa
#9
Orr Ashenberg, Jai Padmakumar, Michael B Doud, Jesse D Bloom
The innate-immune restriction factor MxA inhibits influenza replication by targeting the viral nucleoprotein (NP). Human influenza virus is more resistant than avian influenza virus to inhibition by human MxA, and prior work has compared human and avian viral strains to identify amino-acid differences in NP that affect sensitivity to MxA. However, this strategy is limited to identifying sites in NP where mutations that affect MxA sensitivity have fixed during the small number of documented zoonotic transmissions of influenza to humans...
March 27, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28346095/identification-by-high-throughput-screening-of-pseudomonas-acyl-coenzyme-a-synthetase-inhibitors
#10
Lorenzo Turcano, Daniela Visaggio, Emanuela Frangipani, Antonino Missineo, Matteo Andreini, Sergio Altamura, Paolo Visca, Alberto Bresciani
Pseudomonas infections are common among hospitalized, immunocompromised, and chronic lung disease patients. These infections are recalcitrant to common antibacterial therapies due to inherent antibiotic resistance. To meet the need of new anti- Pseudomonas drugs, a sensitive, homogenous, and robust assay was developed with the aim of identifying inhibitors of acyl-coenzyme A synthetases (ACSs) from Pseudomonas. Given the importance of fatty acids for in vivo nutrition of Pseudomonas, such inhibitors might have the potential to reduce the bacterial fitness during infection...
January 1, 2017: SLAS Discov
https://www.readbyqxmd.com/read/28345980/palliative-care-nursing-for-patients-with-neurological-diseases-what-makes-the-difference
#11
Anna Dieplinger, Firuzan Sari Kundt, Stefan Lorenzl
Neurodegenerative diseases progress slowly, creating increasing physical disability with unpredictable disease trajectories. The disease's life-threatening nature often places these patients in palliative care. There are several factors that complicate the care of patients with neurodegenerative diseases in palliative care units. Owing to physical impairments, there are many communication barriers between patients and staff. Nurses are not able to duplicate the patient's meticulous daily routine leading to caregiver mistrust in the nurse's competencies...
March 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28345943/the-role-of-predictability-in-cooperative-and-competitive-joint-action
#12
Scott Glover, Peter Dixon
Predictability may be an important component of cooperative action, or it may arise as a by-product of involuntary entrainment with another's behavior. Further, differences previously observed in cooperative versus competitive actions may represent a fundamental distinction between behaviors with opposite goals, or they may simply reflect the output of different physical actions. The role of predictability in cooperative versus competitive behavior was directly tested using a joint sequential button-pressing task in which Participant 1 (P1) pressed a key followed by P2 pressing a key...
April 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28345810/an-untrodden-path-versatile-fabrication-of-self-supporting-polymer-stabilized-percolation-membranes-pspms-for-gas-separation
#13
Sebastian Friebe, Alexander Mundstock, Daniel Schneider, Jürgen Caro
The preparation and scalability of zeolite or MOF membranes remains a major challenge, thus preventing the application of these materials in large-scale gas separation. Additionally, several zeolite or MOF materials are quite difficult or nearly impossible to grow as defect-free layers and require expensive macroporous ceramic or polymer supports. Here, we present a new approach for self-supporting zeolite and MOF composite membranes, called Polymer-Stabilized Percolation Membranes (PSPMs) consisting of a pressed gas selective percolation network - in our case ZIF-8, NaX and MIL-140 - and a gas impermeable infiltrated epoxy resin for cohesion...
March 27, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28345803/an-evolving-approach-to-delirium-a-mixed-methods-process-evaluation-of-a-hospital-wide-delirium-program-in-new-zealand
#14
Abdullah Ao Alhaidari, Rosalind Ac Allen-Narker
OBJECTIVE: A process evaluation was carried out to assess and potentially improve the design and implementation of a hospital-wide delirium program. METHODS: A mixed-methods sequential-explanatory design was used; retrospective chart reviews for 100 older (75+) medical inpatients were conducted to measure nurses', doctors' and coders' adherence to key program processes following which interviews were conducted to identify potential barriers to implementation. RESULTS: Delirium occurred in 49% of patients...
March 27, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28345688/a-vacuum-ultraviolet-laser-pulsed-field-ionization-photoion-study-of-methane-ch4-determination-of-the-appearance-energy-of-methylium-from-methane-with-unprecedented-precision-and-the-resulting-impact-on-the-bond-dissociation-energies-of-ch4-and-ch4
#15
Yih-Chung Chang, Bo Xiong, David H Bross, Branko Ruscic, C Y Ng
We report on the successful implementation of a high-resolution vacuum ultraviolet (VUV) laser pulsed field ionization-photoion (PFI-PI) detection method for the study of unimolecular dissociation of quantum-state- or energy-selected molecular ions. As a test case, we have determined the 0 K appearance energy (AE0) for the formation of methylium, CH3(+), from methane, CH4, as AE0(CH3(+)/CH4) = 14.32271 ± 0.00013 eV. This value has a significantly smaller error limit, but is otherwise consistent with previous laboratory and/or synchrotron-based studies of this dissociative photoionization onset...
March 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28345402/clinical-and-functional-correlates-of-processing-speed-in-pediatric-attention-deficit-hyperactivity-disorder-a-systematic-review-and-meta-analysis
#16
Nathan E Cook, Ellen B Braaten, Craig B H Surman
It is well established that processing speed is negatively impacted in children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD). Unfortunately, exactly how processing speed vulnerabilities manifest in daily functioning has not been well established. To support clinical care of youth with ADHD, it is important to better understand the functional consequences and relevant outcomes associated with processing speed deficits. This systematic review and meta-analysis sought to identify the association between processing speed and clinical or functional correlates among children or adolescents diagnosed with ADHD...
March 27, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28345348/mechanistic-insights-into-the-rh-catalyzed-transannulation-of-pyridotriazole-with-phenylacetylene-and-benzonitrile-a-dft-study
#17
Chenli Wang, Yunfei Zhou, Xiaoguang Bao
Computational studies were carried out to explore the mechanisms of Rh2(OAc)4-catalyzed transannulation of pyridotriazole with phenylacetylene and benzonitrile, respectively. For the Rh2(OAc)4-catalyzed divergent cyclization with phenylacetylene, the major product (cyclopropene derivative) might be formed via [2 + 2] cycloaddition to yield a metallacyclobutene intermediate followed by a reductive elimination pathway, where carboxylate ligand lability is considered to release a vacant equatorial site for the formation of Rh-carbenoid...
March 27, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28345067/utility-of-360-degree-assessment-of-residents-in-a-turkish-academic-emergency-medicine-residency-program
#18
Cem Oktay, Yesim Senol, Stephan Rinnert, Yildiray Cete
OBJECTIVES: This study was designed to test a 360-degree assessment tool for four of the emergency medicine resident competencies as outlined by the Council of Residency Directors in Emergency Medicine on patient care, communication skills, professionalism and system based practice in an academic Emergency Department. MATERIAL AND METHODS: Using the competency framework of the American Accreditation Council for Graduate Medical Education, a 57 item-containing assessment tool was created...
March 2017: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28345023/enhancement-of-psma-directed-car-adoptive-immunotherapy-by-pd-1-pd-l1-blockade
#19
Inna Serganova, Ekaterina Moroz, Ivan Cohen, Maxim Moroz, Mayuresh Mane, Juan Zurita, Larissa Shenker, Vladimir Ponomarev, Ronald Blasberg
Chimeric antigen receptor (CAR) T cell therapy in hematologic malignancies has shown remarkable responses, but the same level of success has not been observed in solid tumors. A new prostate cancer model (Myc-CaP:PSMA(+)) and a second-generation anti-hPSMA human CAR T cells expressing a Click Beetle Red luciferase reporter) were used to study hPSMA targeting and assess CAR T cell trafficking and persistence by bioluminescence imaging (BLI). We investigated the antitumor efficacy of human CAR T cells targeting human prostate-specific membrane antigen (hPSMA), in the presence and absence of the target antigen; first alone and then combined with a monoclonal antibody targeting the human programmed death receptor 1 (anti-hPD1 mAb)...
March 17, 2017: Molecular Therapy Oncolytics
https://www.readbyqxmd.com/read/28345020/bacterial-carriers-for-glioblastoma-therapy
#20
Nalini Mehta, Johnathan G Lyon, Ketki Patil, Nassir Mokarram, Christine Kim, Ravi V Bellamkonda
Treatment of aggressive glioblastoma brain tumors is challenging, largely due to diffusion barriers preventing efficient drug dosing to tumors. To overcome these barriers, bacterial carriers that are actively motile and programmed to migrate and localize to tumor zones were designed. These carriers can induce apoptosis via hypoxia-controlled expression of a tumor suppressor protein p53 and a pro-apoptotic drug, Azurin. In a xenograft model of human glioblastoma in rats, bacterial carrier therapy conferred a significant survival benefit with 19% overall long-term survival of >100 days in treated animals relative to a median survival of 26 days in control untreated animals...
March 17, 2017: Molecular Therapy Oncolytics
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