Sylwia Słuczanowska-Głabowska, Marzena Staniszewska, Mariola Marchlewicz, Ewa Duchnik, Karolina Łuczkowska, Krzysztof Safranow, Bogusław Machaliński, Andrzej Pawlik
Psoriasis is a common chronic, inflammatory skin disease characterised by keratinocyte hyperproliferation, parakeratosis, and T-cell infiltration. Adipose tissue has an endocrine function, producing an abundance of cytokines and adipokines. It has also been described that the major adipokines, leptin, resistin, and adiponectin, may be involved in the pathogenesis of psoriasis. The aim of the study was to examine the plasma levels of adiponectin, leptin, and resistin in patients with psoriasis and their correlations with disease activity parameters: Psoriasis Activity Severity Index (PASI), Dermatology Life Quality Index (DLQI), and Body Surface Area (BSA) index, as well as selected clinical parameters...
January 13, 2023: Journal of Clinical Medicine