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https://www.readbyqxmd.com/read/29782512/regulation-of-midgut-cell-proliferation-impacts-aedes-aegypti-susceptibility-to-dengue-virus
#1
Mabel L Taracena, Vanessa Bottino-Rojas, Octavio A C Talyuli, Ana Beatriz Walter-Nuno, José Henrique M Oliveira, Yesseinia I Angleró-Rodriguez, Michael B Wells, George Dimopoulos, Pedro L Oliveira, Gabriela O Paiva-Silva
Aedes aegypti is the vector of some of the most important vector-borne diseases like dengue, chikungunya, zika and yellow fever, affecting millions of people worldwide. The cellular processes that follow a blood meal in the mosquito midgut are directly associated with pathogen transmission. We studied the homeostatic response of the midgut against oxidative stress, as well as bacterial and dengue virus (DENV) infections, focusing on the proliferative ability of the intestinal stem cells (ISC). Inhibition of the peritrophic matrix (PM) formation led to an increase in reactive oxygen species (ROS) production by the epithelial cells in response to contact with the resident microbiota, suggesting that maintenance of low levels of ROS in the intestinal lumen is key to keep ISCs division in balance...
May 21, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29782501/disentangling-the-complexity-of-tropical-small-scale-fisheries-dynamics-using-supervised-self-organizing-maps
#2
Manuel Mendoza-Carranza, Elisabet Ejarque, Leopold A J Nagelkerke
Tropical small-scale fisheries are typical for providing complex multivariate data, due to their diversity in fishing techniques and highly diverse species composition. In this paper we used for the first time a supervised Self-Organizing Map (xyf-SOM), to recognize and understand the internal heterogeneity of a tropical marine small-scale fishery, using as model the fishery fleet of San Pedro port, Tabasco, Mexico. We used multivariate data from commercial logbooks, including the following four factors: fish species (47), gear types (bottom longline, vertical line+shark longline and vertical line), season (cold, warm), and inter-annual variation (2007-2012)...
2018: PloS One
https://www.readbyqxmd.com/read/29782476/acute-neuromuscular-adaptations-in-response-to-low-intensity-blood-flow-restricted-exercise-and-high-intensity-resistance-exercise-are-there-any-differences-erratum
#3
Pedro Fatela, Joana F Reis, Goncalo V Mendonca, Toma S Freitas, Maria J Valamatos, Janne Avela, Pedro Mil-Homens
No abstract text is available yet for this article.
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29782431/the-influence-of-3d-in-single-port-laparoscopy-surgery-an-experimental-study
#4
Jaime Vilaça, Mariana Leite, Jorge Correia-Pinto, Gerrit Högemann, Patrício Costa, Pedro Leão
The aim of this experimental study was to analyze the effect of 3-dimensional (3D) imaging in laparoendoscopic single-site surgery. End points were time, errors, and preference. Twenty-six participants were enrolled in the study, and these were divided into Beginners and Experts, in exercises either with a 2-dimensional or a 3D system. The 4 phantom exercises were chosen from the E-BLUS-European Training in Basic Laparoscopic Urological Skills from the American Fundamentals of Laparoscopic Surgery (FLS) system...
May 18, 2018: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29781934/absolute-reliability-and-concurrent-validity-of-the-stryd-system-for-the-assessment-of-running-stride-kinematics-at-different-velocities
#5
Felipe García-Pinillos, Luis E Roche-Seruendo, Noel Marcén-Cinca, Luis A Marco-Contreras, Pedro A Latorre-Román
García-Pinillos, F, Roche-Seruendo, LE, Marcen-Cinca, N, Marco-Contreras, LA, and Latorre-Román, PA. Absolute reliability and concurrent validity of the Stryd system for the assessment of running stride kinematics at different velocities. J Strength Cond Res XX(X): 000-000, 2018-This study aimed to determine the absolute reliability and to evaluate the concurrent validity of the Stryd system for measuring spatiotemporal variables during running at different velocities (8-20 km·h) by comparing data with another widely used device (the OptoGait system)...
May 17, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29780643/late-diagnosis-of-anomalous-aortic-origin-of-a-coronary-artery-from-the-inappropriate-sinus-of-valsalva-during-investigation-of-chest-pain
#6
Brunna Priscylla Américo Carvalho, Marcio Antônio Dos Santos, Wilson Pedro Guimarães Neto, Júlio César Queiroz De França, Márcio Rogério de Souza Braite, Rodrigo Bottura De Araújo, Isabella Gomes Carvalho, Moacir Fernandes de Godoy
In this work are reported two cases of anomalous aortic origin of a coronary artery (AAOCA), with the left main coronary artery (LMCA) arising at the right sinus of Valsalva in a 77-year-old woman and in a 79-year-old man submitted to angiography after positive ischemic tests. The origin of the LMCA or the left descendant artery (LDA) from the right sinus of Valsalva has a prevalence of 0.2%, the origin of the circumflex artery (CXA) from the right sinus 0.5%, and the origin of the right coronary artery (RCA) from the left sinus of Valsalva has a prevalence of 0...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29780509/self-complementary-nickel-halides-enable-multifaceted-comparisons-of-intermolecular-halogen-bonds-fluoride-ligands-vs-other-halides
#7
Vargini Thangavadivale, Pedro M Aguiar, Naseralla A Jasim, Sarah J Pike, Dan A Smith, Adrian C Whitwood, Lee Brammer, Robin N Perutz
The syntheses of three series of complexes designed with self-complementary motifs for formation of halogen bonds between an iodotetrafluorophenyl ligand and a halide ligand at square-planar nickel are reported, allowing structural comparisons of halogen bonding between all four halides C6 F4 I···X-Ni (X = F, Cl, Br, I). In the series trans -[NiX(2,3,5,6-C6 F4 I)(PEt3 )2 ] 1pX and trans -[NiX(2,3,4,5-C6 F4 I)(PEt3 )2 ] (X = F, Cl, Br, I) 1oX , the iodine substituent on the benzene ring was positioned para and ortho to the metal, respectively...
April 21, 2018: Chemical Science
https://www.readbyqxmd.com/read/29780302/unified-bayesian-estimator-of-eeg-reference-at-infinity-rrest-regularized-reference-electrode-standardization-technique
#8
Shiang Hu, Dezhong Yao, Pedro A Valdes-Sosa
The choice of reference for the electroencephalogram (EEG) is a long-lasting unsolved issue resulting in inconsistent usages and endless debates. Currently, both the average reference (AR) and the reference electrode standardization technique (REST) are two primary, apparently irreconcilable contenders. We propose a theoretical framework to resolve this reference issue by formulating both (a) estimation of potentials at infinity, and (b) determination of the reference, as a unified Bayesian linear inverse problem, which can be solved by maximum a posterior estimation...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29780037/past-and-present-work-practices-of-european-interventional-cardiologists-in-the-context-of-radiation-protection-of-the-eye-lens-results-of-the-euraloc-study
#9
Joanna Karolina Domienik-Andrzejewska, Olivera Ciraj-Bjelac, Panagiotis Askounis, Peter Covens, Octavian Dragusin, Sophie Jacob, Jad Farah, Emilio Gianicolo, Renato Padovani, Pedro Manuel Peixoto Teles, Anders Widmark, Lara Struelens
This paper investigates over five decades of work practices in interventional cardiology with special emphasis on radiation protection. The analysis is based on the data from more than 400 cardiologists from different European countries recruited for EURALOC study collected in the period from 2014 to 2016. Information on the types of procedures performed and their annual mean number, fluoroscopy time, access site choice, X-ray units and radiation protection means used was collected using an occupational questionnaire...
May 21, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29779951/is-the-paradigm-hf-cohort-representative-of-the-real-world-heart-failure-patient-population
#10
Gustavo Rodrigues, António Tralhão, Carlos Aguiar, Pedro Freitas, António Ventosa, Miguel Mendes
INTRODUCTION: A new drug with prognostic impact on heart failure, sacubitril/valsartan, has been introduced in current guidelines. However, randomized trial results can be compromised by lack of representativeness. We aimed to assess the representativeness of the PARADIGM-HF trial in a real-world population of patients with heart failure. METHODS: We reviewed the records of 196 outpatients followed in a heart failure clinic between January 2013 and December 2014...
May 17, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29779814/should-omega-3-fatty-acids-be-used-for-adjuvant-treatment-of-cancer-cachexia
#11
REVIEW
Daryna Sergiyivna Lavriv, Pedro Miguel Neves, Paula Ravasco
OBJECTIVES: Cancer cachexia is characterised by a progressive loss of muscle, resulting in functional impairment and shorter survival. Therefore, omega-3 has been studied for its role as an anti-cachectic therapy. This systematic review identified studies published on use of omega-3 in cancer cachexia in order to examine the potential benefit. METHODS: A systematic review of the literature using PubMed and B-on databases was conducted to identify clinical trials published between 2000 and 2015, to evaluate the effect of n-3 PUFAs on nutritional features and Quality of Life in cancer cachexia...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29779431/translation-and-cross-cultural-adaptation-of-the-pregnancy-physical-activity-questionnaire-ppaq-into-spanish
#12
Irene Coll-Risco, Daniel Camiletti-Moirón, Pedro Acosta-Manzano, Virginia A Aparicio
AIM: The objective of this study was to translate and transculturally adapt into Spanish the Pregnancy Physical Activity Questionnaire. METHODS: The translation procedure included a forward step (translation and synthesis) and a quantitative and qualitative control of the usefulness of the Pregnancy Physical Activity Questionnaire. Afterwards, a prefinal version of the Spanish adapted questionnaire was pretested on 58 pregnant women from Granada (south of Spain)...
May 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29779265/morphology-and-phylogenetic-position-of-gruberia-lanceolata-gruber-1884-ciliophora-heterotrichea-from-rio-de-janeiro-brazil
#13
Pedro H Campello-Nunes, Noemi M Fernandes, Franziska Szokoli, Giulio Petroni, Inácio D da Silva-Neto
Ciliates of the genus Gruberia are poorly studied. Consequently, most species lack detailed morphological descriptions, and all gene sequences in GenBank are not classified at the species level. In this study, a detailed morphological description of a population of G. lanceolata from Brazil is presented, based on live and protargol-stained organisms. We also present the 18S rRNA gene sequence and the phylogenetic position of this species. The primary characteristics of G. lanceolata from the Maricá Lagoon are as follows: an elongate fusiform body 280-870 × 40-160 μm in size; rosy cortical granules; a peristome occupying approximately 1/3-1/2 of body length; an adoral zone comprising 115-330 membranelles; a paroral membrane in 35-50 fragments; and a moniliform macronucleus with 11-16 nodules...
May 19, 2018: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/29779090/8th-international-conference-on-tumor-microenvironment-lisbon-portugal-june-10-14-2018
#14
Pedro Baleia
No abstract text is available yet for this article.
May 19, 2018: Cancer Microenvironment: Official Journal of the International Cancer Microenvironment Society
https://www.readbyqxmd.com/read/29778903/orcokinins-regulate-the-expression-of-neuropeptide-precursor-genes-related-to-ecdysis-in-the-hemimetabolous-insect-rhodnius-prolixus
#15
Juan Pedro Wulff, Natalia Capriotti, Sheila Ons
Ecdysis is a vital process for insects, during which they shed the old cuticle in order to emerge as the following developmental stage. Given its relevance for survival and reproduction, ecdysis is tightly regulated by peptidic hormones that conform an interrelated neuromodulatory network. This network was studied in species that undergo a complete metamorphosis, but not in hemimetabola. In a recent work, we demonstrated that orcokinin neuropeptides are essential for ecdysis to occur in the kissing bug Rhodnius prolixus...
May 17, 2018: Journal of Insect Physiology
https://www.readbyqxmd.com/read/29778806/evaluation-of-antioxidant-potential-of-novel-layered-double-hydroxides-with-caal-and-nial-loaded-with-olanzapine
#16
João Gomes Pontes-Neto, Danilo Augusto Ferreira Fontes, Magaly Andreza Marques de Lyra, Maria Dos Remédios Mendes de Brito, Luíse Lopes Chaves, Pedro José Rolim-Neto, Mônica Felts De La Roca Soares, Lucindo Jose Quintans Júnior, Rivelilson Mendes de Freitas, José Lamartine Soares-Sobrinho
Olanzapine (OLZ), Class II in the Biopharmaceutical Classification System, has low aqueous solubility, hindering its absorption after administration. It is used in the bipolar disorder and schizophrenia treatment, diseases that present the oxidative stress in their pathophysiology. In the search for new Drug Delivery Systems (DDS) that enhance the OLZ dissolution rate, it is also necessary to investigate its antioxidant potential for better understanding. Thus, this study aimed to evaluate the in vitro antioxidant potential of new olanzapine DDS based on two different types of Layered Double Hydroxides (LDH systems)...
May 17, 2018: Life Sciences
https://www.readbyqxmd.com/read/29778642/benefits-of-a-multicomponent-falls-unit-based-exercise-program-in-older-adults-with-falls-in-real-life
#17
Rafael García Molina, Marta Carolina Ruíz Grao, Alicia Noguerón García, Marta Martínez Reig, Mariano Esbrí Víctor, Míkel Izquierdo Redín, Pedro Abizanda Soler
BACKGROUND/OBJECTIVES: Multicomponent exercise programs are the cornerstone in preventing gait and balance impairments and falls in older adults. However, the effects of these programs in usual clinical practice have been poorly analyzed. DESIGN: 4-Month, twice-a-week multicomponent exercise program cohort study in real-life. SETTING: Falls Unit, Complejo Hospitalario Universitario of Albacete, Spain. PARTICIPANTS: Sixty-seven participants who had experienced a fall in the previous year were included...
May 17, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29778594/differetial-toxin-profiles-of-ciguatoxins-in-marine-organisms-chemistry-fate-and-global-distribution
#18
REVIEW
Lucía Soliño, Pedro Reis Costa
Ciguatoxins (CTXs) are fish metabolism products and a result of biotransformation of precursor gambiertoxins produced, in the first instance, by benthic dinoflagellates Gambierdiscus and Fukuyoa. Ciguatoxins are potent neurotoxins that selectively open voltage gated sodium channels in excitable cells causing the human food poisoning known as Ciguatera (CFP). Endemic from tropical areas in central Pacific and West Indian Ocean, and the Caribbean Sea, CTX may affects up to 500,000 people annually due to fish consumption...
May 17, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29778529/ap-1-takes-centre-stage-in-enhancer-chromatin-dynamics
#19
Pedro Madrigal, Kaur Alasoo
Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans have revealed a role for the transcription factor (TF) activator protein 1 (AP-1) in chromatin accessibility. Enhancer selection may be determined not only by cell type-specific sets of TFs but also by broadly expressed ones like AP-1.
May 16, 2018: Trends in Cell Biology
https://www.readbyqxmd.com/read/29778055/new-insights-into-the-effects-of-support-matrix-on-the-removal-of-organic-micro-pollutants-and-the-microbial-community-in-constructed-wetlands
#20
Liang Zhang, Tao Lyu, Carlos Andrés Ramírez Vargas, Carlos A Arias, Pedro N Carvalho, Hans Brix
Constructed wetlands (CWs) are an eco-friendly and cost-effective technology to remove organic micro-pollutants (OMPs) from wastewater. The support matrix is an important component in CWs as it has a primary role in the growth and development of plants and microbes. However, the roles of the support matrix in CWs in removing OMPs have not been systematically studied. Therefore, in this study, six common materials (sand, zeolite, blast iron slag, petcoke, polonite and crushed autoclaved aerated concrete (CAAC)) as support matrixes were firstly investigated by batch tests to explore their adsorption capacities to selected OMPs (ibuprofen, iohexol, tebuconazole and imazalil)...
May 16, 2018: Environmental Pollution
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